EP1351663A1 - Preparations cosmetiques et/ou pharmaceutiques - Google Patents
Preparations cosmetiques et/ou pharmaceutiquesInfo
- Publication number
- EP1351663A1 EP1351663A1 EP02706696A EP02706696A EP1351663A1 EP 1351663 A1 EP1351663 A1 EP 1351663A1 EP 02706696 A EP02706696 A EP 02706696A EP 02706696 A EP02706696 A EP 02706696A EP 1351663 A1 EP1351663 A1 EP 1351663A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- sep
- proteins
- lea
- acid
- skin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
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- 239000000825 pharmaceutical preparation Substances 0.000 title claims abstract description 9
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- 230000005855 radiation Effects 0.000 claims description 9
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- AVKVDDQTHIQFSC-UHFFFAOYSA-N tetradecyl docosanoate Chemical compound CCCCCCCCCCCCCCCCCCCCCC(=O)OCCCCCCCCCCCCCC AVKVDDQTHIQFSC-UHFFFAOYSA-N 0.000 description 1
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- 108060008226 thioredoxin Proteins 0.000 description 1
- 239000010678 thyme oil Substances 0.000 description 1
- 229960000790 thymol Drugs 0.000 description 1
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- 125000002640 tocopherol group Chemical class 0.000 description 1
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- LABSPYBHMPDTEL-JGZVXCDNSA-N trehalose-6-phosphate Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@@H]1O[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](COP(O)(O)=O)O1 LABSPYBHMPDTEL-JGZVXCDNSA-N 0.000 description 1
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- VMYFZRTXGLUXMZ-UHFFFAOYSA-N triethyl citrate Natural products CCOC(=O)C(O)(C(=O)OCC)C(=O)OCC VMYFZRTXGLUXMZ-UHFFFAOYSA-N 0.000 description 1
- 235000013769 triethyl citrate Nutrition 0.000 description 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 1
- 230000001960 triggered effect Effects 0.000 description 1
- HTJNEBVCZXHBNJ-XCTPRCOBSA-H trimagnesium;(2r)-2-[(1s)-1,2-dihydroxyethyl]-3,4-dihydroxy-2h-furan-5-one;diphosphate Chemical compound [Mg+2].[Mg+2].[Mg+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.OC[C@H](O)[C@H]1OC(=O)C(O)=C1O HTJNEBVCZXHBNJ-XCTPRCOBSA-H 0.000 description 1
- OEIXGLMQZVLOQX-UHFFFAOYSA-N trimethyl-[3-(prop-2-enoylamino)propyl]azanium;chloride Chemical compound [Cl-].C[N+](C)(C)CCCNC(=O)C=C OEIXGLMQZVLOQX-UHFFFAOYSA-N 0.000 description 1
- QXJQHYBHAIHNGG-UHFFFAOYSA-N trimethylolethane Chemical compound OCC(C)(CO)CO QXJQHYBHAIHNGG-UHFFFAOYSA-N 0.000 description 1
- FQAZRHVERGEKOS-UHFFFAOYSA-N tripropan-2-yl 2-hydroxypropane-1,2,3-tricarboxylate Chemical compound CC(C)OC(=O)CC(O)(C(=O)OC(C)C)CC(=O)OC(C)C FQAZRHVERGEKOS-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- A61K8/602—Glycosides, e.g. rutin
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- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
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- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
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- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/004—Aftersun preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/007—Preparations for dry skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
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- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/02—Preparations for cleaning the hair
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Alternative & Traditional Medicine (AREA)
- Medical Informatics (AREA)
- Dermatology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Biochemistry (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0100492A FR2819414A1 (fr) | 2001-01-15 | 2001-01-15 | Preparations cosmetiques et/ou pharmaceutiques comprenant des extraits de plantes dites a resurrection |
FR0100492 | 2001-01-15 | ||
PCT/EP2002/000055 WO2002055049A1 (fr) | 2001-01-15 | 2002-01-05 | Preparations cosmetiques et/ou pharmaceutiques |
Publications (1)
Publication Number | Publication Date |
---|---|
EP1351663A1 true EP1351663A1 (fr) | 2003-10-15 |
Family
ID=8858833
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP02703537A Withdrawn EP1351662A1 (fr) | 2001-01-15 | 2002-01-05 | Preparations cosmetiques et/ou pharmaceutiques |
EP02706696A Withdrawn EP1351663A1 (fr) | 2001-01-15 | 2002-01-05 | Preparations cosmetiques et/ou pharmaceutiques |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP02703537A Withdrawn EP1351662A1 (fr) | 2001-01-15 | 2002-01-05 | Preparations cosmetiques et/ou pharmaceutiques |
Country Status (5)
Country | Link |
---|---|
US (3) | US20040109880A1 (fr) |
EP (2) | EP1351662A1 (fr) |
JP (2) | JP2004520338A (fr) |
FR (1) | FR2819414A1 (fr) |
WO (2) | WO2002055049A1 (fr) |
Families Citing this family (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8352400B2 (en) | 1991-12-23 | 2013-01-08 | Hoffberg Steven M | Adaptive pattern recognition based controller apparatus and method and human-factored interface therefore |
US7966078B2 (en) | 1999-02-01 | 2011-06-21 | Steven Hoffberg | Network media appliance system and method |
DE10132003A1 (de) * | 2001-07-03 | 2003-01-30 | Merz & Co Gmbh & Co | Fett(öl)haltiges Mittel, enthaltend Zwiebelextrakt, seine Herstellung und seine Verwendung zur Pflege, Vorbeugung oder Behandlung von geschädigtem Hautgewebe, insbesondere von Narben |
FR2835746B1 (fr) * | 2002-02-14 | 2006-05-26 | Vincience | Composition cosmetique ou pharmaceutique comprenant des hsp et des retinoides, procede de traitement et utilisation |
US20050048460A1 (en) * | 2003-05-29 | 2005-03-03 | The Regents Of The University Of California | Preservative and method for preserving cells |
FR2855968B1 (fr) | 2003-06-13 | 2012-11-30 | Coletica | Stimulation de la synthese et de l'activite d'une isoforme de la lysyl oxydase-like loxl pour stimuler la formation de fibres elastiques |
DE10329004A1 (de) * | 2003-06-27 | 2005-01-13 | Kaanya Cosmetics Gmbh | Kosmetisches Verfahren zur Verminderung sichtbarer Alterungszeichen der Haut |
ME01881B (fr) | 2004-01-22 | 2014-12-20 | Univ Miami | Formulations topiques de coenzyme q10 et procedes d'utilisation |
US8020343B2 (en) * | 2004-12-23 | 2011-09-20 | Becker Underwood Inc. | Enhanced shelf life and on seed stabilization of liquid bacterium inoculants |
US8011132B2 (en) * | 2004-12-23 | 2011-09-06 | Becker Underwood Inc. | Enhanced shelf life and on seed stabilization of liquid bacterium inoculants |
JP4562536B2 (ja) * | 2005-01-27 | 2010-10-13 | 株式会社ノエビア | 皮膚外用剤 |
KR100669362B1 (ko) | 2005-07-25 | 2007-01-16 | 한불화장품주식회사 | 포제를 이용한 권백추출물 제조 방법 및 이를 유효성분으로 함유하는 화장료 조성물 |
DE102005056538A1 (de) * | 2005-11-28 | 2007-05-31 | Merz Pharma Gmbh & Co. Kgaa | Zusammensetzungen, enthaltend Proteine zum Transfer / Recycling strukturell veränderter Lipide aus Biomembranen, sowie deren Anwendungen |
EP2136787B1 (fr) | 2007-03-22 | 2019-08-21 | Berg LLC | Formulations topiques ayant une biodisponibilité amplifiée |
EP3015104A1 (fr) | 2008-04-11 | 2016-05-04 | Berg LLC | Procédés et utilisation permettant d'induire l'apoptose dans des cellules cancéreuses |
WO2010022393A1 (fr) * | 2008-08-22 | 2010-02-25 | P.V. Creations | Produits de soin personnel contenant de l’eau de pluie |
EP2216074A1 (fr) | 2009-02-07 | 2010-08-11 | Cognis IP Management GmbH | Extrait de dolichos biflorus à utiliser dans un traitement cosmétique de la peau |
EP2218455A1 (fr) | 2009-02-07 | 2010-08-18 | Cognis IP Management GmbH | Extrait dolichos biflorus à utiliser dans un traitement thérateutique de la peau |
EP2405888B1 (fr) * | 2009-03-10 | 2018-04-11 | Alfa Biogene International B.V. | Produit de soins cutanés |
EP2110123B1 (fr) * | 2009-03-30 | 2016-03-23 | Shiseido Company, Ltd. | Proliférateur de fibroblaste |
EA034552B1 (ru) | 2009-05-11 | 2020-02-19 | БЕРГ ЭлЭлСи | Способ лечения или предотвращения прогрессирования онкологических заболеваний |
DE102009027696A1 (de) * | 2009-07-14 | 2011-02-10 | Westfälische-Wilhelms Universität Münster | Verwendung von Proanthocyanidinen zur Herstellung einer antiadhäsiven Zubereitung |
KR20200019738A (ko) | 2009-08-26 | 2020-02-24 | 마리 케이 인코포레이티드 | 식물 추출물을 포함하는 국소 피부 케어 제형 |
DE102009039393A1 (de) | 2009-08-31 | 2010-06-10 | Henkel Ag & Co. Kgaa | Antifalten-Kosmetikum mit einem Extrakt aus Sommer-Knotenblumen |
MX2012003563A (es) | 2009-09-24 | 2012-04-30 | Unilever Nv | Agente desinfectante que comprende eugenol, terpineol y timol. |
JP6059859B2 (ja) * | 2009-11-16 | 2017-01-11 | ビーエーエスエフ ビューティ ケア ソリューションズ フランス エスエーエスBASF Beauty Care Solutions France S.A.S. | 弾性繊維の形成を刺激するための、loxl(リシルオキシダーゼ類似)アイソフォームの合成及び活性の刺激 |
FR2953136B1 (fr) * | 2009-11-30 | 2012-05-11 | Expanscience Lab | Extrait de graines de vigna unguiculata et compositions cosmetiques, pharmaceutiques, dermatologiques, nutraceutiques ou alimentaires le comprenant |
ES2389367B2 (es) * | 2009-12-04 | 2013-05-09 | Universidad De Granada | Composición sintética con efecto xeroprotector. |
PE20130045A1 (es) | 2010-03-12 | 2013-01-28 | Berg Pharma Llc | FORMULACIONES INTRAVENOSAS DE COENZIMA Q10 (CoQ10) Y METODOS DE USO DE LAS MISMAS |
FR2958847B1 (fr) * | 2010-04-15 | 2013-06-28 | Isp Investments Inc | Utilisation d'un hydrolysat peptidique de pois en tant qu'agent actif hydratant |
BR112013013085B1 (pt) | 2010-12-07 | 2018-02-14 | Unilever N.V. | Composição de cuidados orais, enxaguante bucal, creme dental, dentífrico, método para desinfetar a cavidade oral e uso de uma composição |
KR101305698B1 (ko) * | 2011-03-29 | 2013-09-09 | 주식회사 바이오에프디엔씨 | 부활초 캘러스 추출물을 함유하는 피부 외용제 조성물 |
ES2762451T3 (es) | 2011-04-04 | 2020-05-25 | Berg Llc | Tratamiento de tumores del sistema nervioso central con coenzima Q10 |
KR102058256B1 (ko) | 2011-06-17 | 2020-01-22 | 버그 엘엘씨 | 흡입성 약제학적 조성물들 |
US9693941B2 (en) | 2011-11-03 | 2017-07-04 | Conopco, Inc. | Liquid personal wash composition |
WO2014065776A1 (fr) * | 2012-10-22 | 2014-05-01 | Empire Technology Development Llc | Agents hydrophiles pour peintures |
FR2997853B1 (fr) * | 2012-11-09 | 2016-11-04 | Oreal | Utilisation d'extrait de myrothamnus flabellifolia et de rhamnose pour lutter contre les signes du vieillissement cutane. |
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KR102436256B1 (ko) * | 2014-12-05 | 2022-08-25 | 코웨이 주식회사 | 미로탐누스 플라벨리폴리아 추출물을 함유하는 환경 스트레스에 대한 피부 보호 효능을 갖는 화장료 조성물 |
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US20190231677A1 (en) * | 2018-01-29 | 2019-08-01 | Mary Kay Inc. | Topical compositions |
CN109223660A (zh) * | 2018-11-22 | 2019-01-18 | 武汉跃莱健康产业有限公司 | 一种焕颜抗衰至肽面霜及其制备方法 |
WO2020172101A1 (fr) | 2019-02-18 | 2020-08-27 | Mary Kay Inc. | Compositions topiques pour la peau destinées au traitement de la rosacée et des rougeurs cutanées |
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KR102238966B1 (ko) * | 2020-07-23 | 2021-04-12 | (주)제니트리 | 자외선 노출에 의한 피부 과민 반응 예방 및 개선용 조성물과 이를 이용한 화장료 |
KR102238993B1 (ko) * | 2020-09-15 | 2021-04-12 | 스킨리버스랩주식회사 | 쌀 발효 추출물, 파인애플 추출물 및 글리세릴 글루코사이드 혼합물을 포함하는 피부 장벽 강화 또는 보습용 화장료 조성물 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2239345A (en) * | 1939-06-19 | 1941-04-22 | Inst Divi Themae Foundation | Proliferation stimulants and process of making same |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2230345A (en) * | 1938-04-25 | 1941-02-04 | Bendix Home Appliances Inc | Cleaning machine |
US2320479A (en) * | 1939-06-19 | 1943-06-01 | Inst Divi Thomae Foundation | Topical remedy |
US2320478A (en) * | 1939-06-19 | 1943-06-01 | Inst Divi Thomae Foundation | Toilet preparation |
DE1815201A1 (de) * | 1968-12-17 | 1970-07-02 | Haarmann & Reimer Gmbh | Verfahren zur Herstellung eines Roestaroma-Grundbouquets |
US4172887A (en) * | 1973-11-30 | 1979-10-30 | L'oreal | Hair conditioning compositions containing crosslinked polyaminopolyamides |
JPH0832621B2 (ja) * | 1985-02-28 | 1996-03-29 | 株式会社資生堂 | 皮膚外用剤 |
GB8607749D0 (en) * | 1986-03-27 | 1986-04-30 | Hetherington A M | Compounds & pharmaceutical preparations |
US5023090A (en) * | 1989-08-16 | 1991-06-11 | Levin Robert H | Topical compositions containing LYCD and other topically active medicinal ingredients for the treatment of ACNE |
JPH02255692A (ja) * | 1989-03-29 | 1990-10-16 | Mitsui Norin Kk | D―グルコーl―グリセロ―3―オクチュロースの製造方法 |
IT1239281B (it) * | 1989-10-27 | 1993-10-19 | Indena Spa | Composizioni per la riduzione dei depositi di grasso superfluo a base di principi attivi di origine vegetale ad attivita' agonista dell'adenilato ciclasi o/e ad attivita' antifosfodiesterasica |
US5348945A (en) * | 1990-04-06 | 1994-09-20 | Wake Forest University | Method of treatment with hsp70 |
JPH06228071A (ja) * | 1993-01-29 | 1994-08-16 | Unitika Ltd | 物質の可溶化処理方法 |
DE4426216A1 (de) * | 1994-07-23 | 1996-01-25 | Merck Patent Gmbh | Benzyliden-Norcampher-Derivate |
DE4426215A1 (de) * | 1994-07-23 | 1996-01-25 | Merck Patent Gmbh | Ketotricyclo [5.2.1.0] decan-Derivate |
FR2735686B1 (fr) * | 1995-06-20 | 1997-09-26 | Oreal | Composition pour proteger et/ou lutter contre les taches et/ou le vieillissement de la peau, ses utilisations |
US5759524A (en) * | 1996-02-09 | 1998-06-02 | The Procter & Gamble Company | Photoprotective compositions |
JPH09249550A (ja) * | 1996-03-18 | 1997-09-22 | Shiseido Co Ltd | 皮膚外用剤 |
EP0818450B1 (fr) * | 1996-07-08 | 2003-01-15 | Ciba SC Holding AG | Dérivés de triazine en tant que filtre UV dans des produits antisolaires |
ES2246501T3 (es) * | 1996-11-29 | 2006-02-16 | Basf Aktiengesellschaft | Preparados cosmeticos y farmaceuticos que contienen filtros uv-a fotoestables. |
US5858712A (en) * | 1997-02-06 | 1999-01-12 | Incyte Pharmaceuticals, Inc. | CDNA encoding a LEA-motif developmental protein homologous to avian px19 |
EP1154753A1 (fr) * | 1999-02-22 | 2001-11-21 | Hemsy, René | Composition a base d'extraits vegetaux pour le soin des cheveux |
JP2001039848A (ja) * | 1999-07-27 | 2001-02-13 | Kao Corp | 皮膚外用剤 |
FR2809308B1 (fr) * | 2000-05-29 | 2003-12-26 | Seporga Lab | Preparations cosmetiques ou dermo-pharmaceutiques contenant des hsp et hsf provenant d'un extrait de champignons ou de levures stresses |
-
2001
- 2001-01-15 FR FR0100492A patent/FR2819414A1/fr not_active Withdrawn
-
2002
- 2002-01-05 JP JP2002555785A patent/JP2004520338A/ja active Pending
- 2002-01-05 WO PCT/EP2002/000055 patent/WO2002055049A1/fr active Application Filing
- 2002-01-05 US US10/250,814 patent/US20040109880A1/en not_active Abandoned
- 2002-01-05 EP EP02703537A patent/EP1351662A1/fr not_active Withdrawn
- 2002-01-05 WO PCT/EP2002/000053 patent/WO2002055048A1/fr active Search and Examination
- 2002-01-05 JP JP2002555784A patent/JP2004529866A/ja active Pending
- 2002-01-05 US US10/250,870 patent/US20040081714A1/en not_active Abandoned
- 2002-01-05 EP EP02706696A patent/EP1351663A1/fr not_active Withdrawn
-
2006
- 2006-10-12 US US11/546,588 patent/US20070134193A1/en not_active Abandoned
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2239345A (en) * | 1939-06-19 | 1941-04-22 | Inst Divi Themae Foundation | Proliferation stimulants and process of making same |
Also Published As
Publication number | Publication date |
---|---|
FR2819414A1 (fr) | 2002-07-19 |
EP1351662A1 (fr) | 2003-10-15 |
WO2002055048A1 (fr) | 2002-07-18 |
US20070134193A1 (en) | 2007-06-14 |
JP2004520338A (ja) | 2004-07-08 |
US20040109880A1 (en) | 2004-06-10 |
JP2004529866A (ja) | 2004-09-30 |
WO2002055049A1 (fr) | 2002-07-18 |
US20040081714A1 (en) | 2004-04-29 |
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