EP1257473A2 - Dispositif de fermeture pour flacons de perfusion et de transfusion - Google Patents

Dispositif de fermeture pour flacons de perfusion et de transfusion

Info

Publication number
EP1257473A2
EP1257473A2 EP01909622A EP01909622A EP1257473A2 EP 1257473 A2 EP1257473 A2 EP 1257473A2 EP 01909622 A EP01909622 A EP 01909622A EP 01909622 A EP01909622 A EP 01909622A EP 1257473 A2 EP1257473 A2 EP 1257473A2
Authority
EP
European Patent Office
Prior art keywords
plastic cover
cap
closure cap
line
particular according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP01909622A
Other languages
German (de)
English (en)
Other versions
EP1257473B1 (fr
Inventor
Roland Amschlinger
Udo BÄCHLER
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Datwyler Pharma Packaging Belgium NV
Original Assignee
Helvoet Pharma NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Helvoet Pharma NV filed Critical Helvoet Pharma NV
Publication of EP1257473A2 publication Critical patent/EP1257473A2/fr
Application granted granted Critical
Publication of EP1257473B1 publication Critical patent/EP1257473B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00—Closures not otherwise provided for
    • B65D51/002—Closures to be pierced by an extracting-device for the contents and fixed on the container by separate retaining means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1412—Containers with closing means, e.g. caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/18—Arrangements for indicating condition of container contents, e.g. sterile condition
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1406—Septums, pierceable membranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1468—Containers characterised by specific material properties
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S215/00—Bottles and jars
    • Y10S215/03—Medical

Definitions

  • the invention relates to a closure cap for
  • 00007 has a central recess from the central area
  • 00025 opens on the front of the plastic lid edge.
  • 00046 fertilizer leads to a kinking behavior that ruptures.
  • 00077 forms a notch valley that is easy to separate.
  • 00084 plastic cover radially outside is larger than radial
  • the ribs are in the bisector of the
  • 00101 ring collar forms as a ring zone, for grasping the
  • FIG. 4 is a plan view of the cap, again showing 00130 an opening phase initiated from the periphery, 00132 00133 Fig. 5 is a side view of this, 00134 00135 Fig. 6 is a bottle provided with the closure dec00136 kel, in vertical section, 00137 locked, 00138 00139 FIG. 7 shows a representation corresponding to FIG. 6,
  • FIG. 8 shows a representation corresponding to FIG. 6,
  • the illustrated cap 1 consists of a
  • 00159 cap 3 is a collar 4 of the flared neck 5 of a bottle
  • the bottle 6 is made of glass, for example.
  • the opening of a cavity 10 of the sealing plug 8 00175 faces the interior 11 of the bottle 6.
  • the Höh00176 lung 10 lies in the actual plug-forming section 0000 and closes recognizably with a horizontal 00178 end face 12 of the collar 4 of the flange neck 5.
  • the 00179 end face 12 is overlapped by an annular flange 13 00181 which is formed onto the sealing plug 8 00180 in the upper region and which is pressed firmly and thus sealingly against the said end face 18183 12 by means of the associated flange 00182.
  • the sealing plug 8 is realized as a pierceable 00186 sealing body. It consists of elastomeric 00187 material, such as butyl rubber.
  • the Ste00188 chen is favored by the cavity 10.
  • This thin-walled zone of the sealing plug 8, given in this way 00189, is declared 00190 as the puncture area 14.
  • the cannula 15 of a Sprit00192 ze 16 shown in FIG. 9 can be regarded as the piercing tool 00191.
  • the content 00193 can be taken from the liquid 00194 17 shown in dashed lines there also via the infusion set, this is done under 00195, the usual hanging, neck-down arrangement of the infusion bottle or transfusion bottle.
  • the related spike is not shown ⁇ 00198.
  • the access of the sealing plug 8 arranged below the brothel 00202 cap 3 is required.
  • Access has a central recess 18 in the ceiling of the flare 00204 cap 3.
  • the central recess 18 is the central region 19 from above 00205 of the plastic cap 2 00207, which extends over the entire upper part of the crimp cap 3.
  • 00208 00209 A ring zone 00211 ne 21 protrudes from the inside 00210 of the ceiling 20 of the plastic cover 2 into the center recess 18.
  • the ring zone 21 occurs in a position-centered manner against 00212 a flanged and thus defused edge 22 of the 00213 center recess 18.
  • the ring zone 21 has from the plane the ceiling 20 has a 00216 projecting standing height of approximately the thickness of the material 00217 of the crimp cap 3. 00218 00219
  • the recess 23 is of the type 00222 therein also accommodate the plastic cover 2 on the flange 00223 cap 3 anchoring undergrip tongues 24.
  • 00224 00225 Said lower gripping tongues 24 are based on a ring collar 00226 realized as ring zone 21.
  • the lower gripping tongues 24, which were originally axially oriented accordingly 00003, are interrupted by gaps 25. It is a total of ⁇ 00232 including six lower gripping tongues 24, each of the same width, 00233 and smaller gaps 25 than the circumferential length of the lower 00234 gripping tongues 24.
  • the ratio of gaps to 00235 tongues is between 1: 2 and 1: 5, preferably 1 00236: 3.
  • the undergrip tongues 24 can be slightly flared, 00239, so that a thermally / mechanically generated spread for 00240 provides the underhand with direction is.
  • 00241 00242 The anchoring situation described is clear from 00243 Figures 6 ff. 00244 cap 1 and bottle 6 are rotationally symmetrical 00245's structure.
  • the relevant longitudinal central axis 00246 bears the reference symbol xx. 00247 00248
  • the plastic cover 2 has radially extending nominal 00249 folding lines I. They are located on the inside 00250 of the ceiling 20 of the plastic cover 2 and are centered 00251.
  • Said set buckling lines I are produced by Mate00252 thinning, this when injection molding 00253 plastic cover 2. 00254 00255 As can be seen clearly in FIG. 1 in particular, 00256 set buckling lines I are at a clear radial distance 00257 y from a center point z of plastic cover 2 beginning00258, realized. This distance y corresponds approximately to 00259 half the radius of the flat-pot-shaped plastic cover 00260 2.
  • the material thinning ends in 00261 center-oriented a circumferential weakening S which runs concentrically to the center z of the plastic cover 00262 2 and into which it opens 00263 openly.
  • the target crease lines I 00264 end peripherally.
  • the radially extending nominal bending lines I continue on the outside edge into an axia00268 le weakening S 'of the plastic cover 2. Going over the 00269 inner corner, the desired kick line I 00270 continues into the axial inner surface 26 of the cylindrical cap wall 27 of the plastic cover 2. The corresponding shape extending over 90 ° is clearly shown in 00273 from FIG. 3. 00274 00275 The radially oriented desired kick line I is designed as a V-recess, seen in 00276 cross section. 00277 are notched valleys.
  • these peri00278 pher connect to the equally profiled axial 00279 chung S 'in the " inner surface 26 of the cap wall 27.
  • the V-recess on the underside 00286 of the ceiling 20 is hidden from view, the V-Aus00287 recess is also forming the weakening S ', practically not recognizable from the outside 00288 00289 00290
  • the circular weakening S realized as a ring trench
  • another cross-section 00292 is based on the profile, namely a U-shaped groove whose 00293 depth is more than two thirds of the basic thickness of the 00294 ceiling 20.
  • V-recesses of the nominal buckling lines I are radial 00297 penetrations of a radial upstream of the circumferential weakening S 00298 outwards Level 29. Accordingly, the material thinning in the area of the set buckling lines I is stronger than in the circumferential weakening S. 00301, namely, the valley bottom 30 of the V-recess of the predetermined kink line 00302 I is lower than the bottom 31 of the circular circumference ⁇ 00303 weakening S. This means that above the valley floor 00304 30 there remains a thinner residual wall on the ceiling 20 than 00305 above the floor 31 of the ring trench.
  • step 29 00320 there is the basic thickness of the cover 20 of the plastic cover 00321.
  • 00322 00323
  • 00325 is embodied in that step-compensating ribs 32 are formed 0000326.
  • 00390 can also be used to destroy an applied logo

Abstract

L'invention concerne un dispositif de fermeture pour flacons de perfusion et de transfusion, comprenant une collerette serrant le col du flacon et maintenant en place un bouchon de fermeture sur le flacon. Cette collerette présente un évidement médian fermé par la partie médiane d'un bouchon en plastique de telle sorte qu'une zone annulaire (21) du bouchon en plastique (2) enveloppe le bord de l'évidement médian. Au moins une ligne (I) de pliage radial est prévue sous la forme d'un amincissement du matériau du bouchon en plastique (2). Dans le but de perfectionner ledit dispositif, l'invention est caractérisée en ce que ladite ligne (I) de pliage se termine par un amincissement circonférentiel (S) à écartement (y) radial par rapport au point central (z) du bouchon en plastique (2).
EP01909622A 2000-02-18 2001-01-13 Dispositif de fermeture pour flacons de perfusion et de transfusion Expired - Lifetime EP1257473B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10007367A DE10007367A1 (de) 2000-02-18 2000-02-18 Verschlusskappe für Infusions- und Transfusionsflaschen
DE10007367 2000-02-18
PCT/EP2001/000376 WO2001060699A2 (fr) 2000-02-18 2001-01-13 Dispositif de fermeture pour flacons de perfusion et de transfusion

Publications (2)

Publication Number Publication Date
EP1257473A2 true EP1257473A2 (fr) 2002-11-20
EP1257473B1 EP1257473B1 (fr) 2004-09-15

Family

ID=7631384

Family Applications (1)

Application Number Title Priority Date Filing Date
EP01909622A Expired - Lifetime EP1257473B1 (fr) 2000-02-18 2001-01-13 Dispositif de fermeture pour flacons de perfusion et de transfusion

Country Status (7)

Country Link
US (1) US6868978B2 (fr)
EP (1) EP1257473B1 (fr)
JP (1) JP2003532591A (fr)
CN (1) CN1205092C (fr)
AU (1) AU2001237300A1 (fr)
DE (2) DE10007367A1 (fr)
WO (1) WO2001060699A2 (fr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10127823C1 (de) * 2001-06-07 2002-08-22 West Pharm Serv Drug Res Ltd Verschluss für eine Medikamentenflasche sowie Verfahren zu dessen Herstellung
US7611026B1 (en) 2002-08-12 2009-11-03 Rexam Closure Systems Inc. Tamper-evident closure having a sealing disk and package for high-temperature applications
US6874647B2 (en) * 2002-08-12 2005-04-05 Owens-Illinois Closure Inc. Plastic closure, closure and container package, and method of manufacture
AR040977A1 (es) * 2002-08-16 2005-04-27 Glaxosmithkline Biolog Sa Disposicion de cierre para un frasco para uso farmaceutico, el frasco, y procedimiento para su llenado y cerrado
US20040118802A1 (en) * 2002-12-19 2004-06-24 Lysfjord John Peter Safety seal for potent product
EP1647226B1 (fr) * 2003-07-18 2013-02-13 Sekisui Chemical Co., Ltd. Recipient ferme hermetiquement et recipient collecteur de substance d'essai sous vide
DE102004035162A1 (de) * 2004-07-20 2006-02-16 Helvoet Pharma Belgium N.V. Pharmazieprodukt-Behältnis
DE102004051300C5 (de) * 2004-10-20 2013-01-24 Fresenius Kabi Deutschland Gmbh Verschlusskappe für mit medizinischen Flüssigkeiten befüllte Behältnisse
US20060090671A1 (en) * 2004-10-29 2006-05-04 Len Ekkert Tamper-evident lid for container
EP1888424A4 (fr) 2005-01-25 2016-09-21 Medical Instill Tech Inc Fermeture de recipient avec une partie sus-jacente pouvant etre penetree par une aiguille et thermiquement rescellable et une partie sous-jacente compatible avec un produit liquide gras et procede correspondant
US20090084804A1 (en) * 2007-10-01 2009-04-02 Hospira, Inc. Snap-over port cap
US8091727B2 (en) * 2007-11-08 2012-01-10 Hospira, Inc. Snap-over clamshell protective port cap
US20090166311A1 (en) * 2007-12-27 2009-07-02 Helvoet Pharma Belgium N.V. Pharmaceutical closure with a laser-applied marking
US8210377B2 (en) * 2008-03-20 2012-07-03 Crown Packaging Technology, Inc. Closure edge protection via polymer coated metal
FR2950035B1 (fr) 2009-09-15 2011-09-02 Raymond A & Cie Coiffe de verrouillage pour recipient a col
FR2950865B1 (fr) 2009-10-01 2011-10-28 Raymond A & Cie Coiffe de verrouillage pour recipient a col avec une capsule a pattes de fixation
DE102011002189A1 (de) 2011-04-20 2012-10-25 Helvoet Pharma Belgium N.V. Verschlusskappe
ES2678545T3 (es) * 2011-09-29 2018-08-13 Ge Healthcare As Envase
US9402782B2 (en) 2011-12-15 2016-08-02 Ge Healthcare As Package with tamper-evident features
FR2986782B1 (fr) * 2012-02-13 2014-03-07 Raymond A & Cie Dispositif de verrouillage de bouchon sur recipient a collerette, recipient a collerette obture par bouchon pourvu d'un tel dispositif de verrouillage
EP2842884A1 (fr) * 2013-08-27 2015-03-04 F. Hoffmann-La Roche AG Fermeture de récipient
CN106963641B (zh) * 2016-01-14 2024-03-01 雷诺丽特恒迅包装科技（北京）有限公司 一种组合盖和具有该组合盖的输液容器
EP4026779A3 (fr) * 2017-12-22 2023-05-31 West Pharmaceutical Services, Inc. Système d'emballage pour un remplissage aseptique de faible volume
FR3098504B1 (fr) * 2019-07-09 2021-06-04 A Raymond Et Cie coiffe de verrouillage pour récipient à col

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Also Published As

Publication number Publication date
CN1205092C (zh) 2005-06-08
EP1257473B1 (fr) 2004-09-15
US20030029828A1 (en) 2003-02-13
JP2003532591A (ja) 2003-11-05
CN1431967A (zh) 2003-07-23
US6868978B2 (en) 2005-03-22
WO2001060699A2 (fr) 2001-08-23
AU2001237300A1 (en) 2001-08-27
WO2001060699A3 (fr) 2002-04-25
DE10007367A1 (de) 2001-08-23
DE50103622D1 (de) 2004-10-21

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