EP1257473A2

EP1257473A2 - Closing cap for infusion and transfusion bottles

Info

Publication number: EP1257473A2
Application number: EP01909622A
Authority: EP
Inventors: Roland Amschlinger; Udo BÄCHLER
Original assignee: Helvoet Pharma NV
Current assignee: Datwyler Pharma Packaging Belgium NV
Priority date: 2000-02-18
Filing date: 2001-01-13
Publication date: 2002-11-20
Anticipated expiration: 2021-01-13
Also published as: JP2003532591A; WO2001060699A2; EP1257473B1; CN1205092C; US6868978B2; DE10007367A1; AU2001237300A1; US20030029828A1; DE50103622D1; WO2001060699A3; CN1431967A

Abstract

The invention relates to a closing cap for infusion and transfusion bottles. The inventive cap is provided with a flanged cap which encompasses a flanged neck of the bottle, secures a closing plug in the bottle and is provided with a middle recess that is closed by the middle region of a plastic lid in such a way that a ring zone (21) of the plastic lid (2) supports the edge of the middle recess from behind. At least one radially extending desired folding line (I) of the plastic lid (2) is embodied. Said line is formed by thinning the material. The aim of the invention is to indicate when said cap has been used. In an advantageous embodiment, the desired folding line (I) opens into a circumferential weakened area (S) that extends at a radial distance (y) from the centre (z) of the plastic lid (2).

Description

00001 Cap for infusion and transfusion bottles

00002

The invention relates to a closure cap for

00004 Infusion and transfusion bottles, with one

00005 flaring neck of the bottle encompassing a closure

00006 stopper crimp cap in the bottle, which

00007 has a central recess from the central area

00008 of a plastic cover is closed in such a way that

00009 a ring zone of the plastic cover the edge of the middle

Engages under recess, with at least one through

00011 material thinning, radially running nominal

00012 crease line of the plastic roof is formed.

00013

00014 A cap of this type is through the

00015 EP 0 291 658 AI known. The radial there, for example

00016 running crease line facilitates removal

00017 of the plastic cover, which as the top cap most

00018 protective metal cap crimped over. About their

00019 then exposed center recess becomes a puncture

00020 range of the stopper cannula or spike accessible

00021 Lich. The radial nominal bending line, implemented as a groove,

00022 continues according to an embodiment of the above

00023 precursor as a radial breakthrough in the wall of the

00024 cap-shaped plastic cover continues. The breakthrough

00025 opens on the front of the plastic lid edge.

00026

Knowing these requirements, the invention has

00028 task, a generic cap

00029 from the aspect of an indication of a start-up

Train 00030 advantageous.

00031

00032 This task is first and foremost

00033 a closure cap with the features of the claim

00034 1 solved, it being based on the fact that the target

00035 kink line in a radial distance from the center 00036 of the plastic cover circumferential weakening

00037 flows out. 00038

According to such an embodiment is a generic

00040 sealing cap of increased safety value achieved. The

00041 use leaves clear traces. A

00042 reuse of the cap in the sense of a

00043 counterfeiting is practically impossible. Such

00044 Protection against counterfeiting of medicines wins

00045 more and more important. The training according to the invention

00046 fertilizer leads to a kinking behavior that ruptures.

00047 The circumferential weakening around a center

00048 not only leads to a fracture crack with regard to the target buckling

00049 lines, but also for a white break indicator in art

00050 fabric lid, this is due to the given geometric

00051 arcuate articulated axis, which is more real but transverse

00052 for the upward folding direction of the folded part of the

00053 pronounced plastic cover. The sight remains best-

00054 hen. The desired effect is further increased by

00055 that the radially running nominal bending line is outside

00056 on the edge into an axial weakening of the plastic cover

00057 kels continues, with the target kink line into the

Shaped 00058 axial inner surface of the plastic cover

Is 00059. This axially oriented weakening occurs as

00060 additional fracture crack. The shape of the weakening

00061 on the inner surface makes the corresponding means

00062 practically not securing the originality from the outside

00063 recognizable. With the first attempt at opening occurs

00064, on the other hand, the crack immediately opens. It brings further

Invention in proposal that the material dilution in

00066 the area of the nominal bending lines is stronger than in the

00067 perimeter weakening. That has advantages with regard to one

00068 easier opening of the bottle, i.e. Kinking the

00069 plastic lid from the periphery. Then is

00070 provided that the circumferential weakening, in the transverse 00071 seen cut, is U-shaped groove. It creates one

00072 Art Ringgraben. Its width can be chosen

00073 that the kink axis is accommodated as a chord. in the

00074 With regard to crack formation, it proves to be

00075 in part that the radial nominal folding line as, in

00076 seen cross section, V-recess is designed. The

00077 forms a notch valley that is easy to separate. A further education

Feature of the invention results from the fact that the

00079 bottom of the V-recess is lower than the sole

00080 the perimeter weakening. Leave fracture crack and white fracture

00081 can be clearly separated from each other. In single

00082 NEN the relevant training looks such that

00083 the wall thickness of the

00084 plastic cover radially outside is larger than radial

00085 inside. In other words: there are higher V-flanks on the outside

00086 reached. A good one, practically close to the middle

00087 taking the crimp cap going support of the plastic

00088 fabric lid is thereby ensured that

00089 the larger wall

00090 the plastic cover strengthens itself radially from the outside,

Spread over the circumference, continues in ribs that extend

Height compensating in the area of lower wall thickness

Raise 00093 and extend to the extent of the circumferential weakening. Advantage-

00094 adhesive, the ribs are in the bisector of the

00095 nominal bending lines are formed continuously. The latter lie

00096 ideally spaced from six equally spaced

00097 ordered nominal buckling lines, or the ones forming them

00098 recesses. A design of even independent

00099 meaning is on a closure that continues in

00100 central area of the plastic cover on the underside

00101 ring collar forms as a ring zone, for grasping the

00102 crimp cap from the central recess, achieved,

00103 by the ring collar continuing in lower gripping tongues

00104 sets which underpin the crimp cap. Such a

00105 wreath of undergrip tongues can be thermally spread 00106 and anchor it so well to the crimp cap. Finally, it is provided that the lower grip tongues detach from the plastic cover when the plastic cover is torn off without removing the 00109 crimp cap. Since the lower gripping tongues 00110 are resilient due to the restoring effect of the material of the plastic cover, the original spreading position 00113 is more or 00112 less exact, which, however, makes it very difficult or not possible for the 00114 lower gripping tongues to pass through the central recess 00115 fend to "thread". This security effect is also important 00116. 00117 00118 The subject matter of the invention is explained in more detail below with reference to 00119 of an exemplary embodiment illustrated in the drawing. It shows: 00121 00122 FIG. 1 the plastic cover of the closure cap in 00123 bottom view, greatly enlarged, 00124 00125 FIG. 2 the section along line II-II in FIG. 1, 00126 00127 FIG. 3 the section along line III-III in FIG. 1 , 00128 00129 Fig. 4 is a plan view of the cap, again showing 00130 an opening phase initiated from the periphery, 00132 00133 Fig. 5 is a side view of this, 00134 00135 Fig. 6 is a bottle provided with the closure dec00136 kel, in vertical section, 00137 locked, 00138 00139 FIG. 7 shows a representation corresponding to FIG. 6,

00140 and that when a border part of the

00141 plastic cover,

00142

00143 FIG. 8 shows a representation corresponding to FIG. 6,

00144 now when the plastic

00145 cover,

00146

00147 Fig. 9 depicting this situation the entnalime of

00148 content, for example of a medicament,

00149 (of course, the bottle is with after

00150 neck positioned below),

00151

00152 Fig. 10 the bottle in a state ready for disposal.

00153

00154 The illustrated cap 1 consists of a

00155 overlapping plastic cover 2 with underlying

00156 metallic crimp cap 3.

00157

00158 The brothels that astride the plastic cover 2

00159 cap 3 is a collar 4 of the flared neck 5 of a bottle

00160 cal 6, for example an infusion bottle,

00161 flared. The beaded rim bears the reference number 7.

00162 The overlying crimp edge is with 3 '

00163 designated.

00164

00165 The bottle 6 is made of glass, for example.

00166

00167 With regard to the metal crimp cap 3 is appropriate

00168 resorted to plastically deformable aluminum.

00169

00170 is then part of the cap 1

00171 sealing plug 8. It is a hollow stop

00172 fen. The sits sealingly in a mouth 9 of the brothel

00173 neck 5 of bottle 6. 00174 The opening of a cavity 10 of the sealing plug 8 00175 faces the interior 11 of the bottle 6. The Höh00176 lung 10 lies in the actual plug-forming section 0000 and closes recognizably with a horizontal 00178 end face 12 of the collar 4 of the flange neck 5. The 00179 end face 12 is overlapped by an annular flange 13 00181 which is formed onto the sealing plug 8 00180 in the upper region and which is pressed firmly and thus sealingly against the said end face 18183 12 by means of the associated flange 00182. 00184 00185 The sealing plug 8 is realized as a pierceable 00186 sealing body. It consists of elastomeric 00187 material, such as butyl rubber. The Ste00188 chen is favored by the cavity 10. This thin-walled zone of the sealing plug 8, given in this way 00189, is declared 00190 as the puncture area 14. The cannula 15 of a Sprit00192 ze 16 shown in FIG. 9 can be regarded as the piercing tool 00191. On the other hand, the content 00193 can be taken from the liquid 00194 17 shown in dashed lines there also via the infusion set, this is done under 00195, the usual hanging, neck-down arrangement of the infusion bottle or transfusion bottle. The related spike is not shown ^¬ 00198. 00199 00200 To expose the central puncture area 14 00201, accordingly, the access of the sealing plug 8 arranged below the brothel 00202 cap 3 is required. Access has a central recess 18 in the ceiling of the flare 00204 cap 3. The central recess 18 is the central region 19 from above 00205 of the plastic cap 2 00207, which extends over the entire upper part of the crimp cap 3. 00208 00209 A ring zone 00211 ne 21 protrudes from the inside 00210 of the ceiling 20 of the plastic cover 2 into the center recess 18. The ring zone 21 occurs in a position-centered manner against 00212 a flanged and thus defused edge 22 of the 00213 center recess 18. 00214 00215 The ring zone 21 has from the plane the ceiling 20 has a 00216 projecting standing height of approximately the thickness of the material 00217 of the crimp cap 3. 00218 00219 The edge 22, which is crimped by folding, protrudes into a 00220 central recess 23 on the top of the sealing plug 8. The recess 23 is of the type 00222 therein also accommodate the plastic cover 2 on the flange 00223 cap 3 anchoring undergrip tongues 24. 00224 00225 Said lower gripping tongues 24 are based on a ring collar 00226 realized as ring zone 21. They are realized in the 00227 demolding state as a series of teeth essentially taking an 00228 cylindrical course (compare FIGS. 1 and 2). The lower gripping tongues 24, which were originally axially oriented accordingly 00003, are interrupted by gaps 25. It is a total of ^¬ 00232 including six lower gripping tongues 24, each of the same width, 00233 and smaller gaps 25 than the circumferential length of the lower 00234 gripping tongues 24. The ratio of gaps to 00235 tongues is between 1: 2 and 1: 5, preferably 1 00236: 3. 00237 00238 The undergrip tongues 24 can be slightly flared, 00239, so that a thermally / mechanically generated spread for 00240 provides the underhand with direction is. 00241 00242 The anchoring situation described is clear from 00243 Figures 6 ff. 00244 cap 1 and bottle 6 are rotationally symmetrical 00245's structure. The relevant longitudinal central axis 00246 bears the reference symbol xx. 00247 00248 The plastic cover 2 has radially extending nominal 00249 folding lines I. They are located on the inside 00250 of the ceiling 20 of the plastic cover 2 and are centered 00251. Said set buckling lines I are produced by Mate00252 thinning, this when injection molding 00253 plastic cover 2. 00254 00255 As can be seen clearly in FIG. 1 in particular, 00256 set buckling lines I are at a clear radial distance 00257 y from a center point z of plastic cover 2 beginning00258, realized. This distance y corresponds approximately to 00259 half the radius of the flat-pot-shaped plastic cover 00260 2. The material thinning ends in 00261 center-oriented a circumferential weakening S which runs concentrically to the center z of the plastic cover 00262 2 and into which it opens 00263 openly. The target crease lines I 00264 end peripherally. 00265 00266 As can be seen in FIG. 2, the radially extending nominal bending lines I continue on the outside edge into an axia00268 le weakening S 'of the plastic cover 2. Going over the 00269 inner corner, the desired kick line I 00270 continues into the axial inner surface 26 of the cylindrical cap wall 27 of the plastic cover 2. The corresponding shape extending over 90 ° is clearly shown in 00273 from FIG. 3. 00274 00275 The radially oriented desired kick line I is designed as a V-recess, seen in 00276 cross section. 00277 are notched valleys. In cross-section, these peri00278 pher connect to the equally profiled axial 00279 chung S 'in the ^" inner surface 26 of the cap wall 27. Seen in 00280 cross section, there is the same V-recess 00281, that is, a notch valley. The latter is of such depth, 00282 that only a rudimentary wall thickness - about 00283 a third - remains, which can be opened with moderate forces 00284 due to breakage crack. Just as with the attached 00285 plastic cover 2 the V-recess on the underside 00286 of the ceiling 20 is hidden from view, the V-Aus00287 recess is also forming the weakening S ', practically not recognizable from the outside 00288 00289 00290 With regard to the circular weakening S realized as a ring trench, another cross-section 00292 is based on the profile, namely a U-shaped groove whose 00293 depth is more than two thirds of the basic thickness of the 00294 ceiling 20. 00295 00296 The V-recesses of the nominal buckling lines I are radial 00297 penetrations of a radial upstream of the circumferential weakening S 00298 outwards Level 29. Accordingly, the material thinning in the area of the set buckling lines I is stronger than in the circumferential weakening S. 00301, namely, the valley bottom 30 of the V-recess of the predetermined kink line 00302 I is lower than the bottom 31 of the circular circumference ^¬ 00303 weakening S. This means that above the valley floor 00304 30 there remains a thinner residual wall on the ceiling 20 than 00305 above the floor 31 of the ring trench. The latter is more stable 00306 due to the low material accumulation, 00307 while the former zone is easier to tear down 00308. 00309 00310 The corresponding relationships are particularly clearly shown in FIG. 2. This representation also makes 00312 obvious that the wall thickness of the plastic cover 2, which is set by the predetermined bending line I through 00313, radially on the outside 00314 is larger than the radial inside. Radially outside, the 00315 V-flanks of the V-recess have a greater vertical slope 00316 height a than the slope height b 00317 measured in this direction in the area of step 29. 00318 00319 peripherally directed outwards, beyond step 29 00320 there is the basic thickness of the cover 20 of the plastic cover 00321. 00322 00323 In the area of step 29, however, there is, at least in part 00324 ell, a height compensation in this regard. 00325 is embodied in that step-compensating ribs 32 are formed 0000326. The relevant details are such 00327 that the larger wall thickness of the plastic cover 2 00329, penetrated by the V-recess of the desired folding line I 00328, extends from the outside radially over the circumference in 00330 the ribs 32, which are smaller in the area 00331 Elevate wall thickness to compensate for height and extend to 00332 circular circumferential weakening S, the groove 28, 00333. 00334 00335 The radially aligned, start the increment 33 00336 ^¬ the ribs 32 lie in the bisector 00337 respectively of adjacent target bending lines I Gradient. A total of 00338, six nominal Knick00339 lines I are distributed at equal angles. 00340 00341 To expose the central puncture area 14 00342 of the sealing plug 8, the edge of the cap of the plastic cover 00343 is gripped under 2 and bent upwards according to FIG. 7 00344. This leads to a fracture crack in the area of the 00345 jacket wall of the cap wall 27. The fracture crack continues, 00346 over the corner to the ceiling 20, in the central oriented 00347 oriented crease lines I of adjacent V-recesses 00348. With upward buckling there is a relative 00349 large sectoral gripping tongue. It can also be two 00350 or more. The upright sectoral gripping tongue 00351 makes it easier to tear off the plastic cover 2 in total, together with 00352. Reference is made to FIG. 8. In the case of two adjacent gripping tongues, the crack edges even increasingly overlap like scissors 00354. The initiation of the fracture crack or break cracks is also true to the line, since 00356 the foothills of the V-recesses in the front 00357 rounded edges of the cap wall 27 form small V-bays 27 '00358. That's where the crack will start. 00359 00360 When the plastic cover 2 is torn off, the 00361 lower gripping tongues 24 detach from their anchoring area. They 00362 are drawn over the edge 22 of the central recess 18. 00364 00365 By means of radially oriented cross ribbing, 23 strips can protrude from the bottom 00366 of the recess into the gaps 25, so 00367 that one can speak of a pocket with regard to the grip under the lower grip tongues 24 00368. 00369 00370 With regard to the fracture crack 00373 se, which clearly leaves traces, along the radially running nominal crease lines I 00372 and the axial weakening S ', a sectoral detachment of the lid part, the so-called gripping lug, occurs radially outside 00373, while it is on the top of the sole 31 00375 of the circumference. mgs weakening S comes to a white-bellied line 34 00 376. This appears as a chord within the radial dimension of the ring trench of the 00378 U-shaped groove 28, which is of sufficient width. Reference is made to FIG. There the 00379 ends the fracture cracks in alignment with the outer flank of the 00380 U-shaped groove 28, while the whitening line 34 as 00381 as already said, chord more affects the further inward 00382 de flank of the U-shaped groove 28 in a plane aligned 00383. The white line 34 forms the geometric 00384 Axis of the folded up sector. The stretched one

00385 whitening line 34 is defined by the nutseiti-

00386 towards the output ends 35 of the target bending lines I, body

00387 borrowed from the V-recesses. 00388

00389 The broken ceiling, as shown in Figure 4,

00390 can also be used to destroy an applied logo

00391 serve and so the reuse of the closure

Exclude 00392 from this optical-visual side. 00393

00394 All disclosed features are (in themselves) inventive

00395 considerably. In the disclosure of the registration is hereby

00396 also the disclosure content of the associated / attached

00397 priority documents (copy of the pre-registration) fully

Include 00398 in content, also for the purpose of characteristics

00399 of these documents in claims of this application

00400 to be included.

Claims

00401 00402 claims 00403 00404 1. closure cap (1) for infusion and transfusion bottles 00405, with a stopper (8) in the 00407 bottle (6) with a flanged neck (5) of the bottle 00406 (6) securing crimp cap (3), which has a 00408 central recess (18) which is closed by the central region 00409 (19) of a plastic cover (2) such that an annular zone (21) of the plastic cover (2) 00411 the edge (22) of the Underneath the central recess (18), 00412 wherein at least one radially extending nominal crease line (I) of the plastic cover (2) formed by material thinning00413 is formed, characterized in that the nominal crease line (I) is at a radial distance of 00416 (y) to the center (z) of the plastic cover 00417 (2) circumferential weakening (S) opens. 00418 00419 2. Closure cap according to claim 1 or in particular da00420 according to, characterized in that the radially extending 00421 de nominal kick line (I) continues on the outer edge side in a 00422 axial weakening (S ¹ ) of the plastic cover (2) 00423, the nominal The short line (I) is formed 00425 into the -axial 00424 inner surface (26) of the plastic cover (2). 00426 00427 3. Closure cap according to one or more of the preceding claims 00428 or in particular according thereto, characterized in 00429 that the thinning of the material in the area 00430 of the predetermined fold lines (I) is stronger than in that of the 00431 circumferential weakening (S). 00432 00433 4. Cap according to one or more of the preceding claims or in particular according thereto, thereby 00435 characterized in that the circumferential weakening (S) is a U-shaped groove (28), seen in 00436 cross section. 00437 00438 5. Closure cap according to one or more of the preceding claims or in particular according to it, 00440 characterized in that the radial desired crease line (I) 00441 is designed as a V-recess, seen in cross section. 00442 00443 6. Cap according to one or more of the preceding 00444 claims or in particular according thereto, characterized in 00445 that the valley bottom (30) of the V-Ausnehm00446 ung is lower than the sole (31) of the circumferential weakening (S). 00448 00449 7. Closure cap according to one or more of the preceding 00450 claims or in particular according thereto, characterized 00451 in that the wall thickness of the plastic cover (2) penetrated by the desired kick line (I) 00452 is 00453 radially larger on the outside than radially on the inside. 00454 00455 8. Closure cap according to one or more of the preceding claims 00456 or in particular according thereto, characterized 00457 in that the larger wall thickness of the plastic cover 00459 (2) penetrated by the predetermined folding line (I) 00458 (2) extends radially from the outside over the circumference ver00460 divides, continues into ribs (32), which rise in the area 00461 of lower wall thickness to compensate for height and extend 00462 to the circumferential weakening (S). 00463 00464 9. Closure cap according to one or more of the preceding claims or in particular according to it, characterized in 00466 that the ribs (32) run in the angular neckline 00467 of the predetermined bending lines (I). 00468

00469 10. Closure cap according to one or more of the preceding claims or in particular according to it, gekenn00471 is characterized by six 00472 nominal bending lines (I) which are distributed at equal angles. 00473 00474 11. Closure cap according to one or more of the preceding claims, or in particular according to it, wherein in the 00476 central area of the plastic cover (2) on the underside 00477 an annular collar is designed as an annular zone (21) for 00478 to underneath the crimp cap (3) from the central recess 00479 ( 18), characterized in that the ring collar 00480 gene continues in lower gripping tongues (24) which underlie the 00481 crimp cap (3). 00482 00483 12. Closure according to one or more of the preceding00484 claims or in particular according thereto, characterized gekenn00485 that the lower gripping tongues (24) when the plastic cover (2) is torn off 00486 detach from it without taking the Bör00487 del cap (3). 00488