EP1219356B1 - Austragvorrichtung für fliessfähige Medien mittels einer Schubkolbenpumpe - Google Patents

Austragvorrichtung für fliessfähige Medien mittels einer Schubkolbenpumpe Download PDF

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Publication number
EP1219356B1
EP1219356B1 EP02007105A EP02007105A EP1219356B1 EP 1219356 B1 EP1219356 B1 EP 1219356B1 EP 02007105 A EP02007105 A EP 02007105A EP 02007105 A EP02007105 A EP 02007105A EP 1219356 B1 EP1219356 B1 EP 1219356B1
Authority
EP
European Patent Office
Prior art keywords
discharge device
discharge
outlet
pump
outlet opening
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP02007105A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP1219356A2 (de
EP1219356A3 (de
Inventor
Stefan Ritsche
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aptar Radolfzell GmbH
Original Assignee
Erich Pfeiffer GmbH
Ing Erich Pfeiffer GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19700437A external-priority patent/DE19700437B4/de
Application filed by Erich Pfeiffer GmbH, Ing Erich Pfeiffer GmbH filed Critical Erich Pfeiffer GmbH
Publication of EP1219356A2 publication Critical patent/EP1219356A2/de
Publication of EP1219356A3 publication Critical patent/EP1219356A3/de
Application granted granted Critical
Publication of EP1219356B1 publication Critical patent/EP1219356B1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/02—Membranes or pistons acting on the contents inside the container, e.g. follower pistons
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B15/00—Details of spraying plant or spraying apparatus not otherwise provided for; Accessories
    • B05B15/60—Arrangements for mounting, supporting or holding spraying apparatus
    • B05B15/65—Mounting arrangements for fluid connection of the spraying apparatus or its outlets to flow conduits
    • B05B15/652—Mounting arrangements for fluid connection of the spraying apparatus or its outlets to flow conduits whereby the jet can be oriented
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/0005—Components or details
    • B05B11/0037—Containers
    • B05B11/0039—Containers associated with means for compensating the pressure difference between the ambient pressure and the pressure inside the container, e.g. pressure relief means
    • B05B11/0044—Containers associated with means for compensating the pressure difference between the ambient pressure and the pressure inside the container, e.g. pressure relief means compensating underpressure by ingress of atmospheric air into the container, i.e. with venting means

Definitions

  • the WO 93/00172 A shows a nebulizer with a long, relatively thin outlet trunk.
  • Applicant discloses using media reservoirs for only one discharge stroke, which are closed with a stopper simultaneously serving as a piston, whereby the stopper is pierced by a needle for actuation.
  • the EP-B-521,022 shows a dual atomizer in which the thrust piston pump is limited by a gate on the periphery of the housing, which is indexed for a second stroke.
  • the invention aims to design a dispensing device so that the application to certain locations, e.g. Within body openings, especially on hard to reach places to allow, while the dead volume of the dispensing device should be kept low.
  • the outlet trunk in a nasal passage, in particular the inner nostril for the application of a medicament, preferably a vaccine or immunizing agent against colds, such as influenza.
  • a medicament preferably a vaccine or immunizing agent against colds, such as influenza.
  • a medicament preferably a vaccine or immunizing agent against colds, such as influenza.
  • the described shape of the outlet spout allows the introduction into this area.
  • the outlet spout In order to allow insertion of the outlet spout into the corresponding curved areas of the nasal cavity, it can bend or the like, such as a bend, a kink or the like. have or branch off angled from the nozzle section. He himself also elastic or plastically flexible, i. be flexible, so that it adapts itself to the introduction into a nasal passage itself.
  • a disposable dual atomizer for dispensing two consecutive subbatches as a spray. He has on a base body a projecting nose adapter with nozzle actuation shoulders for supporting two fingers and an in the body hineinind Wegbaren operating part with an actuating sleeve and a media storage held therein, the closure piston plug can be pierced by a hollow needle.
  • a ring is attached via predetermined breaking points by means of spokes, which breaks off at a first actuation while maintaining a minimum actuation pressure. The spokes strike a stop and thereby limit the first partial stroke.
  • By rotation of the actuating sleeve of the actuating portion is brought into start position for the second stroke. There, inserted by means of material bridges intermediate webs are broken, whereby the second partial stroke is carried out while maintaining a minimum actuation force.
  • the pressure point fuse may contain at least one predetermined breaking point. Most preferably, it is provided on a snap-in ring, e.g. is formed on destructible material bridges on a forming an actuating handle, the media container receiving sleeve.
  • This snap-in ring makes it possible to provide the material bridges on one of the two parts to be joined, in which case after the separation of the material bridges of the snapped on the other part ring remains at this.
  • a stop is preferably provided, the stop elements are formed for example in the region of the ring-bearing spokes.
  • the main body movable part ie the actuating sleeve with the media storage
  • a fixed stop so as to ensure that not equal to the second Austraghubhand is triggered.
  • an unlocking operation is performed first, for example, by rotation of the two relatively movable parts against each other.
  • actuating sleeve now separated from the ring spokes can be rotated to a position where they lie in the range of webs, which in turn are connected via predetermined breaking points with the body.
  • This rotational position can by projecting wall sections be limited to prevent overspeeding.
  • a second actuation occurs, in turn break the predetermined breaking points between the web and the body, so that a executed with a minimum actuation force second discharge stroke is performed.
  • the media storage is hermetically sealed until it is used for the first time.
  • the associated with her or formed by her discharge remains open after the first stroke, so that in the subsequent second stroke immediately the atomization can begin.
  • the discharge device 11 shown in the drawing has a base body 12 which consists of plastic injection molding. He has a central elongated nozzle portion 13, in his inventive training in the 6 and 7 is shown and adapted in its shape and length to the particular application. In the present case, it is a so-called nose adapter, which is intended to be inserted into a nostril of a patient. At its upper ends, it has a discharge opening 14 in the form of a spray nozzle with an upstream angle chamber. At this point, a sleeve-shaped piston rod carrier 15 is provided inside the hollow nozzle portion 13, in which a likewise hollow piston rod 16 is pressed down.
  • a piston plunger 17 in shape a hollow steel needle beveled at its lower free end similar to a hypodermic needle, by means of a seal surrounding the needle 18.
  • This needle-shaped piston plunger 17 passes completely through the piston rod and is zoomed up to the discharge opening 14, so its interior forms a discharge channel 19.
  • the dispensed pharmaceutical medium 24 is provided in a medium container 20, which is formed as a cylindrical, closed down and open at the top, provided with a lateral flange glass container similar to an ampoule. It also forms the media reservoir and the pump chamber 23, so that its inner walls are simultaneously the cylinder bore of a thrust piston pump 46.
  • Your piston 21 is formed by a piston plug, which consists of rubber or rubber-like material and in the middle has a membrane 22 in the form of a middle piece with a small wall thickness, which can be pierced by the piston plunger 17.
  • the media container 20 is received in an actuating and receiving sleeve 25 which is in the form of a very elongated closed down plastic sleeve with inner support ribs for the media container. Its closed bottom 26 forms an actuating surface for the discharge device 11. It is guided between ribs 45 in the interior of the nozzle section together with the media container and axially movable therein.
  • first pressure point fuse 27 On the outer circumference a first pressure point fuse 27 is formed. It consists of three connecting webs or spokes 29 ( Fig. 3 ), which are connected via material bridges 30 with a circumferential outer ring 28. This is received in a defined by a guide groove 42 circumferential position with its outer periphery in a snap connection 32 which is provided in a cylindrical base portion 34 of the body, namely at its lower edge.
  • the Material bridges are designed so that they break when applying a predetermined operating pressure ( Fig. 2 ).
  • An inner rib 48 of the base portion 34 secures the ring 28 in its axial position.
  • the base portion 34 extends downwardly from actuating shoulders 35, which are generally oval in area (FIG. Fig. 4 ) surrounding the central nozzle portion 13 and down a stiffening edge 36 have.
  • the spokes 29 have, as out Fig. 3 can be seen, lateral reinforcements and are stiffened by support ribs 31 in the axial direction.
  • the outer surface of the actuating sleeve 25 has an outer handle in the form of a corrugation.
  • Fig. 4 Inside the base portion 34 are made Fig. 4 provided to recognize walls 44 which project downwards. They form three arc sections 49 and then extend on both sides to the circumference of the base portion to the outside, so that they form slots 43 between them. Between the walls 44 are platelets or webs 40, which form a second pressure point fuse 39 for a second stroke. They are connected via material bridges 41 with the walls. One of the walls 44 is extended and forms a rotation stop 38 against which one of the spokes 29 strikes during one rotation.
  • the parts in the in Fig. 1 assembled situation shown.
  • the medium container 20 filled with the medium 24 is received in the actuating sleeve 25 and its pump chamber 23 is sealed by the piston plug 21 locked. It is located at a distance from the tip of the piston plunger 17 when the actuating sleeve is in the starting position, which is defined by the fact that the ring 28 of the first pressure point fuse 27 is engaged in the snap device 32 and rests against the underside of the ribs 48.
  • the resulting ready-to-use dispensing device is now grasped by the user as needed by placing two fingers on the actuating shoulders 35 and pressing the actuating surface 26 with the thumb.
  • a sufficient operating pressure tear the material bridges 30, which form a predetermined breaking point, so that the actuating sleeve now with a predetermined force and accordingly high operating speed in Fig. 1 is moved upward.
  • the piston rod 16 pushes the plunger stopper in the media container 20 and the medium 24 is released via the discharge channel 19 in the needle and the outlet opening 14 as a spray. This happens while the patient has inserted the neck portion 13 into one of his nostrils.
  • the patient may now insert the neck portion 13 into his second nostril after preparing the dispenser for the second dispensing stroke.
  • the Spokes 29 each stand at about 30 ° distance from the slots 43 in the walls 44. They were at the end of the first Austragshub stage approximately in the middle of sections 49 struck them. They are now rotated by the rotation until they are above the slots 43.
  • a rotation stop serves the downwardly extended wall portion which forms the rotation stop 38.
  • the discharge device makes it possible to output the individual partial batches with high dosing accuracy and reliability; if desired from in different quantities.
  • the partial strokes are different because of the idle paths to be traversed during the first actuation, which is taken into account in the design. It is possible to adapt the dispenser for other purposes, such as for medicines intended for eyes or other mating or multiple sites of use. Also for several successive applications in the form of spray or different output form, for example, the treatment at intervals of a few minutes to the same application site, the device can be used.
  • the discharge device 11 corresponds to the explained below according to the invention training of the Fig. 1 to 5 , Their description is referred to. The same parts bear the same reference numerals.
  • the spigot portion 13 tapers towards its end and merges into an outlet spout 50 integrally formed therewith and elongate and thin.
  • Its diameter is between 3 and 4 mm or below, but usually not more than 5 mm, and it is over 10 mm, preferably between 20 and 30 mm long.
  • the ratio Reusselbett to diameter is about 7 and should be advantageous over 5.
  • He is circular cylindrical and has at its end the outlet opening 15 in the form of a spray nozzle. This is a small diameter hole formed in the outlet spout 50 which, together with swirling channels 51 formed in the front end of a filler 52, forms a nozzle with a conical spray jet.
  • the filler 52 is formed integrally with the piston rod 16 and has on its outer side ducts 53 of very small cross-section in the form of molded-in longitudinal grooves.
  • the longitudinal piece fills an inner channel 54 of the hollow outlet spout 50, which minimizes the dead space for the exiting medium.
  • the ducts 53 are over a by a diameter reduction of the unit filler / piston rod formed distribution chamber 53 connected to the inner bore of the needle 17.
  • the outlet trunk 50 is flexibly flexible, in the region of a hinged kink 56, which lies in a central region of the outlet. It is formed by the fact that the filler 52a is reduced in diameter in the region of the kink in that it is easily flexible due to the flexibility of its material.
  • the material of the outlet spout is flexible enough that it allows a certain hose-like bend.
  • bellows-like folds could be molded to facilitate bending.
  • the outlet trunk is inserted by the doctor or another competent person and aligned accordingly. Thereafter, the discharge device is operated in the manner previously described to perform a first stroke section. Thereafter, the outlet trunk is inserted into the second nostril and the second lift section triggered after it has been unlocked, if necessary.
  • a certain hand position can be given by appropriate design of the finger support shoulders, so that the doctor automatically hits the right place.

Landscapes

  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Reciprocating Pumps (AREA)
  • Details Of Reciprocating Pumps (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Valve Device For Special Equipments (AREA)
  • Threshing Machine Elements (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Closures For Containers (AREA)
  • Devices For Dispensing Beverages (AREA)
  • Coating Apparatus (AREA)
EP02007105A 1997-01-09 1998-01-08 Austragvorrichtung für fliessfähige Medien mittels einer Schubkolbenpumpe Expired - Lifetime EP1219356B1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE19700437 1997-01-09
DE19700437A DE19700437B4 (de) 1996-01-23 1997-01-09 Austragvorrichtung für fließfähige Medien mittels einer Schubkolbenpumpe
DE19723133 1997-06-03
DE19723133A DE19723133A1 (de) 1997-06-03 1997-06-03 Austragvorrichtung für Medien
EP98904040A EP0951362B1 (de) 1997-01-09 1998-01-08 Austragvorrichtung für fliessfähige medien mittels einer schubkolbenpumpe

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
EP98904040A Division EP0951362B1 (de) 1997-01-09 1998-01-08 Austragvorrichtung für fliessfähige medien mittels einer schubkolbenpumpe

Publications (3)

Publication Number Publication Date
EP1219356A2 EP1219356A2 (de) 2002-07-03
EP1219356A3 EP1219356A3 (de) 2002-08-28
EP1219356B1 true EP1219356B1 (de) 2010-07-28

Family

ID=7831207

Family Applications (3)

Application Number Title Priority Date Filing Date
EP02007105A Expired - Lifetime EP1219356B1 (de) 1997-01-09 1998-01-08 Austragvorrichtung für fliessfähige Medien mittels einer Schubkolbenpumpe
EP98904040A Expired - Lifetime EP0951362B1 (de) 1997-01-09 1998-01-08 Austragvorrichtung für fliessfähige medien mittels einer schubkolbenpumpe
EP98109321A Expired - Lifetime EP0882516B1 (de) 1997-06-03 1998-05-22 Spender für Medien

Family Applications After (2)

Application Number Title Priority Date Filing Date
EP98904040A Expired - Lifetime EP0951362B1 (de) 1997-01-09 1998-01-08 Austragvorrichtung für fliessfähige medien mittels einer schubkolbenpumpe
EP98109321A Expired - Lifetime EP0882516B1 (de) 1997-06-03 1998-05-22 Spender für Medien

Country Status (14)

Country Link
US (2) US6321942B1 (https=)
EP (3) EP1219356B1 (https=)
JP (2) JP4046769B2 (https=)
KR (2) KR100492350B1 (https=)
CN (1) CN1103642C (https=)
AT (3) ATE475487T1 (https=)
AU (2) AU734535B2 (https=)
BR (2) BR9807065A (https=)
CA (1) CA2277208C (https=)
DE (5) DE19723133A1 (https=)
DK (2) DK0951362T3 (https=)
ES (1) ES2176960T3 (https=)
PT (1) PT951362E (https=)
WO (1) WO1998030335A1 (https=)

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DE102012203866A1 (de) * 2011-03-16 2012-09-20 Consort Medical Plc Fluidabgabevorrichtung
DE102012203866B4 (de) * 2011-03-16 2013-08-29 Consort Medical Plc Fluidabgabevorrichtung
US8590750B2 (en) 2011-03-16 2013-11-26 Consort Medical Plc Fluid delivery device

Also Published As

Publication number Publication date
ATE277689T1 (de) 2004-10-15
CN1103642C (zh) 2003-03-26
AU6987498A (en) 1998-12-10
WO1998030335A1 (de) 1998-07-16
DE19723133A1 (de) 1998-12-10
EP0882516A1 (de) 1998-12-09
AU734535B2 (en) 2001-06-14
DE59812015D1 (de) 2004-11-04
BR9807065A (pt) 2000-05-02
JP4046769B2 (ja) 2008-02-13
KR100492350B1 (ko) 2005-05-31
EP1219356A2 (de) 2002-07-03
CA2277208C (en) 2007-12-11
EP1219356A3 (de) 2002-08-28
CN1250398A (zh) 2000-04-12
DK0951362T3 (da) 2002-07-15
KR100559101B1 (ko) 2006-07-25
PT951362E (pt) 2002-11-29
ATE475487T1 (de) 2010-08-15
KR19990006599A (ko) 1999-01-25
ES2176960T3 (es) 2002-12-01
DE59814459D1 (de) 2010-09-09
KR20000069945A (ko) 2000-11-25
AU6207598A (en) 1998-08-03
US6059150A (en) 2000-05-09
CA2277208A1 (en) 1998-07-16
JPH10338298A (ja) 1998-12-22
ATE219391T1 (de) 2002-07-15
JP2001509070A (ja) 2001-07-10
BR9801755A (pt) 1999-06-01
EP0882516B1 (de) 2004-09-29
DE59804505D1 (de) 2002-07-25
EP0951362A1 (de) 1999-10-27
EP0951362B1 (de) 2002-06-19
DE29824620U1 (de) 2001-11-15
DK0882516T3 (da) 2005-01-17
US6321942B1 (en) 2001-11-27
AU740121B2 (en) 2001-11-01

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