EP1080113A4 - TREATMENT OF HUMAN TUMORS USING RADIATION AND GROWTH FACTOR RECEPTOR TYROSINE KINASE INHIBITORS - Google Patents

TREATMENT OF HUMAN TUMORS USING RADIATION AND GROWTH FACTOR RECEPTOR TYROSINE KINASE INHIBITORS

Info

Publication number
EP1080113A4
EP1080113A4 EP99924253A EP99924253A EP1080113A4 EP 1080113 A4 EP1080113 A4 EP 1080113A4 EP 99924253 A EP99924253 A EP 99924253A EP 99924253 A EP99924253 A EP 99924253A EP 1080113 A4 EP1080113 A4 EP 1080113A4
Authority
EP
European Patent Office
Prior art keywords
inhibitors
radiation
treatment
growth factor
factor receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99924253A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP1080113A1 (en
Inventor
Harlan W Waksal
Mansoor N Saleh
Francisco Robert
Donald Jay Buchsbaum
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UAB Research Foundation
ImClone LLC
Original Assignee
UAB Research Foundation
ImClone Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UAB Research Foundation, ImClone Systems Inc filed Critical UAB Research Foundation
Publication of EP1080113A1 publication Critical patent/EP1080113A1/en
Publication of EP1080113A4 publication Critical patent/EP1080113A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP99924253A 1998-05-15 1999-05-14 TREATMENT OF HUMAN TUMORS USING RADIATION AND GROWTH FACTOR RECEPTOR TYROSINE KINASE INHIBITORS Withdrawn EP1080113A4 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US79612 1987-07-30
US206138 1988-06-13
US8561398P 1998-05-15 1998-05-15
US7961298A 1998-05-15 1998-05-15
US85613P 1998-05-15
US20613898A 1998-12-07 1998-12-07
PCT/US1999/010741 WO1999060023A1 (en) 1998-05-15 1999-05-14 Treatment of human tumors with radiation and inhibitors of growth factor receptor tyrosine kinases

Publications (2)

Publication Number Publication Date
EP1080113A1 EP1080113A1 (en) 2001-03-07
EP1080113A4 true EP1080113A4 (en) 2002-04-17

Family

ID=27373511

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99924253A Withdrawn EP1080113A4 (en) 1998-05-15 1999-05-14 TREATMENT OF HUMAN TUMORS USING RADIATION AND GROWTH FACTOR RECEPTOR TYROSINE KINASE INHIBITORS

Country Status (14)

Country Link
EP (1) EP1080113A4 (xx)
JP (1) JP2002515511A (xx)
KR (1) KR20010071271A (xx)
CN (1) CN1314917A (xx)
AU (1) AU4079999A (xx)
BR (1) BR9910511A (xx)
CA (1) CA2332331A1 (xx)
CZ (1) CZ20004224A3 (xx)
HK (1) HK1040720A1 (xx)
IL (1) IL139707A0 (xx)
MX (1) MXPA00011248A (xx)
PL (1) PL348634A1 (xx)
SK (1) SK17282000A3 (xx)
WO (1) WO1999060023A1 (xx)

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SALEH M ET AL: "In vitro and in vivo evaluation of the cytotoxicity of radiation combined with chimeric monoclonal antibody to the epidermal growth factor receptor.", PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH ANNUAL, vol. 37, 1996, 87th Annual Meeting of the American Association for Cancer Research;Washington, D.C., USA; April 20-24, 1996, 1996, pages 612, XP001027768, ISSN: 0197-016X *
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See also references of WO9960023A1 *

Also Published As

Publication number Publication date
CA2332331A1 (en) 1999-11-25
EP1080113A1 (en) 2001-03-07
JP2002515511A (ja) 2002-05-28
BR9910511A (pt) 2001-11-20
CN1314917A (zh) 2001-09-26
CZ20004224A3 (cs) 2002-02-13
KR20010071271A (ko) 2001-07-28
AU4079999A (en) 1999-12-06
MXPA00011248A (es) 2004-09-06
HK1040720A1 (zh) 2002-06-21
PL348634A1 (en) 2002-06-03
IL139707A0 (en) 2002-02-10
SK17282000A3 (sk) 2002-04-04
WO1999060023A1 (en) 1999-11-25

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