EP0815211A1 - Neue, definierte enzymmischungen zur zellgewinnung und für die wundbehandlung - Google Patents

Neue, definierte enzymmischungen zur zellgewinnung und für die wundbehandlung

Info

Publication number
EP0815211A1
EP0815211A1 EP96907436A EP96907436A EP0815211A1 EP 0815211 A1 EP0815211 A1 EP 0815211A1 EP 96907436 A EP96907436 A EP 96907436A EP 96907436 A EP96907436 A EP 96907436A EP 0815211 A1 EP0815211 A1 EP 0815211A1
Authority
EP
European Patent Office
Prior art keywords
collagenase
cells
gly
pro
enzymes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP96907436A
Other languages
German (de)
English (en)
French (fr)
Inventor
Claus Otto Markert
Hans Thom
Jürgen Weymann
Wolfgang Zahn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott GmbH and Co KG
Original Assignee
Knoll GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19532906A external-priority patent/DE19532906A1/de
Application filed by Knoll GmbH filed Critical Knoll GmbH
Publication of EP0815211A1 publication Critical patent/EP0815211A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/6448Elastases, e.g. pancreatic elastase (3.4.21.36); leukocyte elastase (3.4.31.37)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
EP96907436A 1995-03-16 1996-03-12 Neue, definierte enzymmischungen zur zellgewinnung und für die wundbehandlung Withdrawn EP0815211A1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE19509584 1995-03-16
DE19509584 1995-03-16
DE19532906A DE19532906A1 (de) 1995-03-16 1995-09-07 Neue, definierte Enzymmischungen zur Zellgewinnung und für die Wundbehandlung
DE19532906 1995-09-07
PCT/EP1996/001044 WO1996028543A1 (de) 1995-03-16 1996-03-12 Neue, definierte enzymmischungen zur zellgewinnung und für die wundbehandlung

Publications (1)

Publication Number Publication Date
EP0815211A1 true EP0815211A1 (de) 1998-01-07

Family

ID=26013440

Family Applications (1)

Application Number Title Priority Date Filing Date
EP96907436A Withdrawn EP0815211A1 (de) 1995-03-16 1996-03-12 Neue, definierte enzymmischungen zur zellgewinnung und für die wundbehandlung

Country Status (13)

Country Link
US (1) US6146626A (no)
EP (1) EP0815211A1 (no)
JP (1) JPH11501517A (no)
AU (1) AU702514B2 (no)
BR (1) BR9607143A (no)
CA (1) CA2213723A1 (no)
CZ (1) CZ280397A3 (no)
EA (1) EA000583B1 (no)
HU (1) HUP9901188A2 (no)
IL (1) IL117479A (no)
NO (1) NO974260L (no)
PL (1) PL322271A1 (no)
WO (1) WO1996028543A1 (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5718897A (en) * 1995-06-07 1998-02-17 Trustees Of Tufts College Enhancing keratinocyte migration and proliferation
US5830741A (en) * 1996-12-06 1998-11-03 Boehringer Mannheim Corporation Composition for tissue dissociation containing collagenase I and II from clostridium histolyticum and a neutral protease
WO2003011333A1 (en) * 2001-07-27 2003-02-13 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Botulinum toxin in the treatment or prevention of acne
US7364565B2 (en) 2001-07-27 2008-04-29 Ramot At Tel Aviv University Ltd. Controlled enzymatic removal and retrieval of cells
US7811560B2 (en) * 2006-01-30 2010-10-12 Auxilium Us Holdings, Llc Compositions and methods for treating collagen-mediated diseases
US8323642B2 (en) * 2006-12-13 2012-12-04 Depuy Mitek, Inc. Tissue fusion method using collagenase for repair of soft tissue
US20100159564A1 (en) * 2007-11-30 2010-06-24 Dwulet Francis E Protease resistant recombinant bacterial collagenases
MX2012006661A (es) 2009-12-08 2012-11-12 Healthpoint Ltd Composiciones enzimaticas de desbridamiento de heridas con actividad enzimatica mejorada.
HUE057423T2 (hu) 2012-01-12 2022-05-28 Endo Global Ventures Clostridium histolyticum enzim
CN115969318A (zh) 2017-03-01 2023-04-18 恩多风投有限公司 用于评估和治疗橘皮组织的装置和方法
AU2018244426A1 (en) 2017-03-28 2019-10-17 Endo Ventures Limited Improved method of producing collagenase
CN109694845A (zh) * 2018-12-25 2019-04-30 中国医学科学院北京协和医院 用于分离单细胞的试剂盒及其应用
WO2023228873A1 (ja) * 2022-05-24 2023-11-30 国立研究開発法人国立成育医療研究センター 肝細胞の製造方法、肝細胞の接着性改善剤、および肝細胞

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0673456B2 (ja) * 1986-04-26 1994-09-21 三共株式会社 ヒト・膵臓エラスタ−ゼ▲i▼
US5162205A (en) * 1986-04-26 1992-11-10 Sankyo Company, Limited Human pancreatic elastase I
AU4644793A (en) * 1992-06-22 1994-01-24 Trigen, Inc. Molecular cloning of the genes reponsible for collagenase production from clostridium histolyticum
WO1996000283A1 (en) * 1994-06-24 1996-01-04 Boehringer Mannheim Corporation A purified mixture of collagenases and two other proteases obtained from clostridium histolyticum

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO9628543A1 *

Also Published As

Publication number Publication date
CZ280397A3 (cs) 1998-04-15
HUP9901188A2 (hu) 1999-08-30
IL117479A0 (en) 1996-07-23
JPH11501517A (ja) 1999-02-09
EA000583B1 (ru) 1999-12-29
WO1996028543A1 (de) 1996-09-19
EA199700241A1 (ru) 1998-02-26
IL117479A (en) 1999-12-22
PL322271A1 (en) 1998-01-19
CA2213723A1 (en) 1996-09-19
US6146626A (en) 2000-11-14
BR9607143A (pt) 1997-11-25
AU702514B2 (en) 1999-02-25
NO974260D0 (no) 1997-09-15
AU5106696A (en) 1996-10-02
NO974260L (no) 1997-11-14
MX9706725A (es) 1997-11-29

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