HUP9901188A2 - Új, meghatározott enzimkeverékek sejtkinyeréshez és sebkezeléshez - Google Patents

Új, meghatározott enzimkeverékek sejtkinyeréshez és sebkezeléshez

Info

Publication number
HUP9901188A2
HUP9901188A2 HU9901188A HUP9901188A HUP9901188A2 HU P9901188 A2 HUP9901188 A2 HU P9901188A2 HU 9901188 A HU9901188 A HU 9901188A HU P9901188 A HUP9901188 A HU P9901188A HU P9901188 A2 HUP9901188 A2 HU P9901188A2
Authority
HU
Hungary
Prior art keywords
mixtures
treating wounds
enzyme mixtures
obtaining cells
new defined
Prior art date
Application number
HU9901188A
Other languages
English (en)
Inventor
Claus Otto Markert
Hans Thom
Jürgen Weymann
Wolfgang Zahn
Original Assignee
Knoll Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19532906A external-priority patent/DE19532906A1/de
Application filed by Knoll Aktiengesellschaft filed Critical Knoll Aktiengesellschaft
Publication of HUP9901188A2 publication Critical patent/HUP9901188A2/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6448—Elastases, e.g. pancreatic elastase (3.4.21.36); leukocyte elastase (3.4.31.37)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

A találmány Clőstridiűm histőlyticűmból származó tisztítőtt enzimekmeghatárőzőtt összetételű keverékeinek előállítására és alkalmazásáravőnatkőzik. Ezek az enzimek vagy keverékeik sejtek vagyszövetfragmentűmők emberi vagy állati szövetekből való reprődűkálható,standardizált kinyerésére alkalmazhatók. A találmány ennélfőgvaezeknek az enzimeknek - egyenként vagy keverékek alkőtórészeiként -közvetlen vagy közvetett gyógyászati alkalmazására - példáűlsebkezelésben - vőnatkőzik. ŕ
HU9901188A 1995-03-16 1996-03-12 Új, meghatározott enzimkeverékek sejtkinyeréshez és sebkezeléshez HUP9901188A2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19509584 1995-03-16
DE19532906A DE19532906A1 (de) 1995-03-16 1995-09-07 Neue, definierte Enzymmischungen zur Zellgewinnung und für die Wundbehandlung

Publications (1)

Publication Number Publication Date
HUP9901188A2 true HUP9901188A2 (hu) 1999-08-30

Family

ID=26013440

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9901188A HUP9901188A2 (hu) 1995-03-16 1996-03-12 Új, meghatározott enzimkeverékek sejtkinyeréshez és sebkezeléshez

Country Status (13)

Country Link
US (1) US6146626A (hu)
EP (1) EP0815211A1 (hu)
JP (1) JPH11501517A (hu)
AU (1) AU702514B2 (hu)
BR (1) BR9607143A (hu)
CA (1) CA2213723A1 (hu)
CZ (1) CZ280397A3 (hu)
EA (1) EA000583B1 (hu)
HU (1) HUP9901188A2 (hu)
IL (1) IL117479A (hu)
NO (1) NO974260L (hu)
PL (1) PL322271A1 (hu)
WO (1) WO1996028543A1 (hu)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5718897A (en) * 1995-06-07 1998-02-17 Trustees Of Tufts College Enhancing keratinocyte migration and proliferation
US5830741A (en) * 1996-12-06 1998-11-03 Boehringer Mannheim Corporation Composition for tissue dissociation containing collagenase I and II from clostridium histolyticum and a neutral protease
US7364565B2 (en) 2001-07-27 2008-04-29 Ramot At Tel Aviv University Ltd. Controlled enzymatic removal and retrieval of cells
KR100602308B1 (ko) * 2001-07-27 2006-07-18 더 보드 오브 수퍼바이저스 오브 루이지애나 스테이트 유니버시티 앤드 애그리컬춰럴 앤드 미케니칼 칼리지 여드름의 치료 또는 예방을 위한 보툴리눔 독소
US7811560B2 (en) * 2006-01-30 2010-10-12 Auxilium Us Holdings, Llc Compositions and methods for treating collagen-mediated diseases
US8323642B2 (en) * 2006-12-13 2012-12-04 Depuy Mitek, Inc. Tissue fusion method using collagenase for repair of soft tissue
US20100159564A1 (en) * 2007-11-30 2010-06-24 Dwulet Francis E Protease resistant recombinant bacterial collagenases
WO2011071986A1 (en) 2009-12-08 2011-06-16 Healthpoint, Ltd. Enzymatic wound debriding compositions with enhanced enzymatic activity
NZ750379A (en) 2012-01-12 2022-10-28 Auxilium Int Holdings Inc Clostridium histolyticum enzymes and methods for the use thereof
BR112019018277A2 (pt) 2017-03-01 2020-06-30 Endo Ventures Limited aparelho e método para avaliar e tratar celulite
MX2019011574A (es) 2017-03-28 2019-12-19 Endo Ventures Ltd Método mejorado para producir aplicaciones relacionadas con la colagenasa.
CN109694845A (zh) * 2018-12-25 2019-04-30 中国医学科学院北京协和医院 用于分离单细胞的试剂盒及其应用
WO2023228873A1 (ja) * 2022-05-24 2023-11-30 国立研究開発法人国立成育医療研究センター 肝細胞の製造方法、肝細胞の接着性改善剤、および肝細胞

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0673456B2 (ja) * 1986-04-26 1994-09-21 三共株式会社 ヒト・膵臓エラスタ−ゼ▲ｉ▼
US5162205A (en) * 1986-04-26 1992-11-10 Sankyo Company, Limited Human pancreatic elastase I
CA2138948A1 (en) * 1992-06-22 1994-01-06 Hun-Chi Lin Molecular cloning of the genes responsible for collagenase production from clostridium histolyticum
WO1996000283A1 (en) * 1994-06-24 1996-01-04 Boehringer Mannheim Corporation A purified mixture of collagenases and two other proteases obtained from clostridium histolyticum

Also Published As

Publication number Publication date
CZ280397A3 (cs) 1998-04-15
WO1996028543A1 (de) 1996-09-19
EA199700241A1 (ru) 1998-02-26
JPH11501517A (ja) 1999-02-09
IL117479A (en) 1999-12-22
IL117479A0 (en) 1996-07-23
NO974260D0 (no) 1997-09-15
NO974260L (no) 1997-11-14
BR9607143A (pt) 1997-11-25
CA2213723A1 (en) 1996-09-19
MX9706725A (es) 1997-11-29
AU5106696A (en) 1996-10-02
US6146626A (en) 2000-11-14
EP0815211A1 (de) 1998-01-07
PL322271A1 (en) 1998-01-19
EA000583B1 (ru) 1999-12-29
AU702514B2 (en) 1999-02-25

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