EP0540814A1 - Verschlusskappe für pharmazeutische Behälter - Google Patents

Verschlusskappe für pharmazeutische Behälter Download PDF

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Publication number
EP0540814A1
EP0540814A1 EP92108745A EP92108745A EP0540814A1 EP 0540814 A1 EP0540814 A1 EP 0540814A1 EP 92108745 A EP92108745 A EP 92108745A EP 92108745 A EP92108745 A EP 92108745A EP 0540814 A1 EP0540814 A1 EP 0540814A1
Authority
EP
European Patent Office
Prior art keywords
groove
closure cap
area
lid
plastic cover
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP92108745A
Other languages
German (de)
English (en)
French (fr)
Inventor
Klaus Derksen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pohl GmbH and Co KG
Original Assignee
Pohl GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pohl GmbH and Co KG filed Critical Pohl GmbH and Co KG
Publication of EP0540814A1 publication Critical patent/EP0540814A1/de
Ceased legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00—Closures not otherwise provided for
    • B65D51/002—Closures to be pierced by an extracting-device for the contents and fixed on the container by separate retaining means

Definitions

  • the invention relates to a closure cap for the sterile sealing of a bottle with pharmaceutical content sealed with a rubber-elastic sealing element, wherein a crimp capsule overlaps the sealing element with a lid area and the bottle neck with a flange edge and is connected to the bottle neck in an edge zone arranged below the edge of the bottle neck.
  • the lid area is covered by a plastic lid and in its central area is connected to the plastic lid by a first attachment point, the attachment point being enclosed by a circular tear line and the plastic lid having a diametrically extending predetermined kink, in which its cross section through a groove is weakened.
  • Such a cap is known from DE-PS 37 15 175.
  • the task of this known closure cap for infusion and transfusion bottles is that the closure cap can be detached relatively easily despite being firmly connected to the crimp cap.
  • the tear line essentially cylindrically surrounds the central area of the crimping capsule and that it is therefore difficult and cumbersome to separate the bottle, sealing element and crimping capsule after use with a view to recycling the parts.
  • the invention has for its object to develop a cap of the type mentioned in such a way that the crimp capsule and the sealing element and a lid used can be easily separated from the glass bottle to the mostly expensive bottle made of special glass for recycling feed.
  • the closure cap should be able to be opened easily and safely by the operating personnel using small forces, without the risk of an unintentional overall tearing of the crimp capsule from the bottle neck.
  • the closure cap according to the invention is characterized in that the lid area and the plastic lid are connected to one another radially outside the tear line by a second fastening point, that the groove intersects an imaginary connecting line of the first and the second fastening point essentially vertically and that the tear line is recessed in the area of the groove is.
  • the advantage here is that the closure cap ensures a germ-free seal between the plastic lid and the crimp cap, even with small bottle diameters, and a plastic lid arranged on the lid surface in a rotationally fixed manner, which releases the rubber-elastic sealing element in the middle area in a first operating section using small forces of the operating personnel . Due to the exposed center in the lid area, the liquid can now be removed from the bottle with a syringe.
  • Unintentional tearing of the crimp capsule is reliably prevented by the non-self-contained tear line and the desired kink and the second fastening point of the plastic cover arranged behind the desired kink in the opening direction.
  • the closure cap can be completely removed from the bottle by moving the plastic lid in the opening direction is lifted further from the lid area.
  • only a comparatively small expenditure of force is necessary, since the pulling out of the complete pulling-out part is facilitated by the plastic cover designed as a lever.
  • both the lid area and the flange edge of the aluminum crimp capsule have a segment-shaped recess that extends from the center of the lid area to the lower area of the flange edge.
  • the crimp capsule can be easily removed and then the rubber-elastic sealing element that was intended for sterile sealing of the bottle.
  • the groove can be opened in a direction facing away from the cover area.
  • the groove has a V-shaped cross section and that the groove is delimited by flank surfaces which form an angle of at least 85 ° and at most 150 °.
  • an obtuse angle which is approximately 100 to 135 ° is preferably used.
  • the preferably obtuse-angled design of the V-shaped groove is particularly advantageous when the pharmaceutical content of the bottle is not to be removed by completely removing the cap, but rather, for example, by a syringe which penetrates the central recess in the lid area and the rubber-elastic sealing elements. The part of the plastic cover which is initially lifted off and is at the front in the opening direction does not hinder the removal of the liquid, since it completely releases the central region of the crimp capsule.
  • the plastic cover can have a circularly delimited surface.
  • the production of such plastic lids and the closing of the bottles with pharmaceutical content in filling machines is particularly easy.
  • the filled bottles can also be stored in a particularly space-saving manner.
  • the plastic cover can at least partially cover the flange edge of the crimp capsule, the cover in the area of the groove being at least partially removed by recesses.
  • the advantage here is that the force required to expose the central recess in the cover surface is further reduced, which at the same time further reduces the already low risk of unintentional tearing of the entire crimp capsule.
  • the recesses in the cover extend into the area of the inner surface of the plastic cover.
  • the plastic lid can be provided with an integrally molded opening tab.
  • the tear line can be provided with an extension parallel to the connecting line at least at one point, the extension preferably extending past the second fastening point into the area of the flange edge. This configuration ensures simple and targeted tearing off of the entire crimp capsule.
  • Removing the crimp capsule is even easier if the tear line ends in two extensions, the two extensions on either side of the second attachment point are provided. It is also possible to use such a crimp capsule in diameter ranges below 20 mm. To completely remove the crimp capsule, the pull-out part is separated from the crimp capsule in the opening direction. This essentially straight-line movement sequence requires the cap to be opened quickly.
  • Fig. 1 the bottle closed by the cap according to the invention is shown in a view.
  • the various opening sections of the closure cap until they are completely separated are shown in the corresponding order and in a sectional view.
  • the individual parts are shown greatly enlarged.
  • FIG. 2 shows the plastic cover from FIG. 1 in a top view and a section along the line A - A.
  • Fig. 3 the plastic lid of the closure cap according to the invention is shown in a view and a section.
  • a closure cap is shown, which is arranged on the bottle neck 2.1 of a bottle 2 with pharmaceutical content.
  • a sealing element 1 made of rubber-elastic material is arranged within the bottle neck 2.1 and covers the axial limitation of the bottle neck 2.1 in the radial direction.
  • the cap essentially comprises a crimp capsule 3 made of aluminum sheet, which the sealing element 1 with a lid area 3.1 and the bottle neck 2.1 with a Flange border 3.2 overlaps.
  • the crimp capsule 3 is fixed on the bottle neck 2.1 in the region of the edge zone 4, which is formed by a constriction.
  • the cover area 3.1 has a centrally arranged central recess 3.3, which is underneath a one-piece molded central area 5.1 of the plastic cover 5.
  • the plastic cover 5 is provided with a diametrically extending predetermined kink 8, so that the cover can be opened by the operating personnel using small forces. The following must be carried out for the function of the sealing cap:
  • the cap for infusion and transfusion bottles 2 has two functions.
  • a first opening section which is shown in the drawing in FIG. 1b
  • the plastic cover 5 the central region 5.1 of which engages under the central recess 3.3 of the crimp capsule 3, is first raised until the sealing element 1 arranged under the central recess 3.3 is exposed.
  • the plastic cover 5 is expediently bent up until the boundary lines of the desired kink 8 abut one another.
  • the open first section of the plastic cover 5 then, as in this example, forms an angle of 110 ° with the cover surface 3.1.
  • the central recess 3.3 of the crimp capsule 3 and the rubber-elastic sealing element 1 arranged underneath are particularly easy to access.
  • Very low forces for opening the central recess 3.3 are required if the plastic cover 5 has a reduced material thickness in the area of the predetermined kink 8.
  • the plastic cover 5 takes a pull-out part 7 through its central region 5.1 and the first fastening point 9.1, which is usually limited by a perforation of the crimp capsule 3.
  • a second attachment point 9.2 is arranged, which engages under a further recess of the cover area 3.1.
  • the crimp capsule 3 still holds the rubber-elastic sealing element 1 in FIG. 1b firmly on the bottle 2.
  • the liquid can be removed from the bottle 2 with a syringe through the sealing element 1, for example .
  • FIGS. 1c and 1d The second operating section for completely removing the closure cap is shown in FIGS. 1c and 1d.
  • the starting position is shown in FIG. 1b, in which the second fastening point 9.2 is formed by a recess in the cover surface 3.1 and a projection of the plastic cover 5. The projection engages under the recess in a manner similar to that in the area of the first fastening point 9.1.
  • tear line 14 can be designed differently, it being only of crucial importance that the perforation in the central region 5.1 is not circular cylindrical and is self-contained.
  • tear line 14 preferably extends essentially in the radial direction from the center of the lid area 3.1 past the second fastening point 9.2 to the area of the lower flange edge 3.2. This results in a segment-shaped opening of the crimp capsule 3 starting from the central recess 3.3 into the lower region of the flange edge 3.2.
  • Fig. 1d the cap is shown shortly before the complete removal from the bottle neck 2.1.
  • FIG. 2 shows a top view of the plastic cover 5 and a section of the plastic cover 5 along the line A -A.
  • the desired kink 8 is inserted in the opening direction 6 between the central region 5.1 and the second fastening point 9.2 arranged radially behind it.
  • the predetermined kink which forms the groove base of the V-shaped recess, is arranged in the direction of the second fastening point 9.2. This requires a greater leverage effect with respect to the opening of the central recess 3.3 under the central area 5.1.
  • the section in FIG. 2 shows the central region 5.1 of the plastic cover 5.
  • FIG. 3 a side view of the plastic cover 5 shown in FIG. 2 can be seen from the left and a representation cut along the line B -B.
  • the second attachment point 9.2 has a smaller diameter than the first attachment point 9.1.
  • the rear boundary, which partially covers the flange edge 3.2 of the crimp capsule 3, is used, as shown in FIGS. 1c and 1d, as a further lever for completely tearing off the closure cap.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Closures For Containers (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
EP92108745A 1991-10-04 1992-05-23 Verschlusskappe für pharmazeutische Behälter Ceased EP0540814A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4132896 1991-10-04
DE4132896A DE4132896C1 (ja) 1991-10-04 1991-10-04

Publications (1)

Publication Number Publication Date
EP0540814A1 true EP0540814A1 (de) 1993-05-12

Family

ID=6442025

Family Applications (1)

Application Number Title Priority Date Filing Date
EP92108745A Ceased EP0540814A1 (de) 1991-10-04 1992-05-23 Verschlusskappe für pharmazeutische Behälter

Country Status (4)

Country Link
US (1) US5447247A (ja)
EP (1) EP0540814A1 (ja)
JP (1) JP2659893B2 (ja)
DE (1) DE4132896C1 (ja)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4238983C1 (ja) * 1992-11-19 1993-09-23 Pohl Gmbh & Co Kg, 7500 Karlsruhe, De
US5931828A (en) * 1996-09-04 1999-08-03 The West Company, Incorporated Reclosable vial closure
USD422712S (en) * 1997-09-12 2000-04-11 Becton, Dickinson And Company Closure for specimen collection container
FR2769003B1 (fr) * 1997-09-26 1999-11-19 Oreal Flacon en verre ou ceramique comportant un element rapporte
US6173851B1 (en) 1999-03-18 2001-01-16 Anesta Corporation Method and apparatus for the interim storage of medicated oral dosage forms
DE10007367A1 (de) * 2000-02-18 2001-08-23 Helvoet Pharma Verschlusskappe für Infusions- und Transfusionsflaschen
US7243799B2 (en) * 2001-05-15 2007-07-17 Cephalon, Inc. Portable container for disposing of a medicated oral dosage form
DE10138191B4 (de) * 2001-08-03 2004-02-26 Helvoet Pharma Belgium N.V. Verschluss für Infusions- oder Transfusionsflaschen
TWI303565B (en) * 2002-08-16 2008-12-01 Glaxosmithkline Biolog Sa Closure system,vial having the closure system,method of closing a vial,method of filling a pharmaceutical vial, and vial closure
KR200336235Y1 (ko) * 2003-08-30 2003-12-18 김상훈 병마개 및 이를 구비한 병
ES1055823Y (es) * 2003-10-27 2004-05-01 Salido Yolanda Chia Biberon esteril.
US8757408B2 (en) * 2007-07-19 2014-06-24 Brad T. Joubert Bottle closure with chamber for holding an item
US9371162B2 (en) * 2008-12-09 2016-06-21 Weatherchem Corporation One-piece dispensing closure
US8550313B2 (en) 2009-03-12 2013-10-08 Weatherchem Corporation Sift-resistant dispensing closure
DE102011002189A1 (de) * 2011-04-20 2012-10-25 Helvoet Pharma Belgium N.V. Verschlusskappe
WO2013034594A1 (en) 2011-09-06 2013-03-14 Novo Nordisk A/S Pharmaceutical container, a method of manufacture thereof and a kit containing the pharmaceutical container
FR2986782B1 (fr) * 2012-02-13 2014-03-07 Raymond A & Cie Dispositif de verrouillage de bouchon sur recipient a collerette, recipient a collerette obture par bouchon pourvu d'un tel dispositif de verrouillage
DE102012102881A1 (de) * 2012-04-03 2013-10-10 Datwyler Pharma Packaging International Nv Verfahren zur Herstellung einer Bördelkappe, Bördelkappe und Behältnis mit Bördelkappe
EP2842884A1 (en) * 2013-08-27 2015-03-04 F. Hoffmann-La Roche AG Cap for a container
FR3098504B1 (fr) * 2019-07-09 2021-06-04 A Raymond Et Cie coiffe de verrouillage pour récipient à col

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1929797A1 (de) * 1968-06-24 1970-01-08 Wimmer Pharma Gummi Gmbh Verschlussanordnung fuer Medikamentenflaschen od.dgl.
EP0291658A1 (de) * 1987-05-07 1988-11-23 Pohl GmbH & Co. KG Verschlusskappe für Infusions und Transfusionsflaschen

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2395149A (en) * 1944-09-11 1946-02-19 John E B Shaw Parenteral bottle construction
AT278563B (de) * 1967-02-14 1970-02-10 Schmalbach Lubeca Verschlußdeckel aus Kunststoff
NO150234C (no) * 1977-05-09 1984-09-12 Asicomo As Kapselformet lukke for beholderaapning og fremgangsmaate til fremstilling av lukket
SE416191B (sv) * 1977-06-20 1980-12-08 Rigello Pak Ab Forslutningsanordning for forpackningsbehallare
US4289234A (en) * 1980-06-16 1981-09-15 Rutschke Roger M Cigarette package closure
JPS5859749U (ja) * 1981-10-16 1983-04-22 オリンパス光学工業株式会社 容器用キヤツプ
US4664277A (en) * 1983-03-14 1987-05-12 The West Company Bonded closure assembly
US4471879A (en) * 1983-08-04 1984-09-18 The West Company Metal overcap for pharmaceutical and similar containers
DE3336344C2 (de) * 1983-10-06 1986-05-07 Franz Pohl, Metall- und Kunststoffwarenfabrik GmbH, 7500 Karlsruhe Kappenverschluß für einen Behälter mit pharmazeutischem Inhalt
US4723693A (en) * 1986-10-02 1988-02-09 Dart Industries, Inc. Double hinging cap
IT213756Z2 (it) * 1988-04-18 1990-02-16 Capsulit Srl Cappuccio di sigillo particolarmente per flaconi di antibiotici e di infusione e trasfusione.
US5080245A (en) * 1990-03-22 1992-01-14 The West Company Incorporated Bidirectional scoring

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1929797A1 (de) * 1968-06-24 1970-01-08 Wimmer Pharma Gummi Gmbh Verschlussanordnung fuer Medikamentenflaschen od.dgl.
EP0291658A1 (de) * 1987-05-07 1988-11-23 Pohl GmbH & Co. KG Verschlusskappe für Infusions und Transfusionsflaschen

Also Published As

Publication number Publication date
DE4132896C1 (ja) 1993-01-21
JPH05270560A (ja) 1993-10-19
US5447247A (en) 1995-09-05
JP2659893B2 (ja) 1997-09-30

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