EG18408A - Process for preparing novel substituted quinoline derivatives - Google Patents

Process for preparing novel substituted quinoline derivatives

Info

Publication number
EG18408A
EG18408A EG520/87A EG52087A EG18408A EG 18408 A EG18408 A EG 18408A EG 520/87 A EG520/87 A EG 520/87A EG 52087 A EG52087 A EG 52087A EG 18408 A EG18408 A EG 18408A
Authority
EG
Egypt
Prior art keywords
6alkyl
phenyl
quinoline derivatives
novel substituted
substituted quinoline
Prior art date
Application number
EG520/87A
Other languages
English (en)
Original Assignee
Smith Kline French Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab
Application granted granted Critical
Publication of EG18408A publication Critical patent/EG18408A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • C07D215/44—Nitrogen atoms attached in position 4 with aryl radicals attached to said nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
EG520/87A 1986-09-05 1987-09-03 Process for preparing novel substituted quinoline derivatives EG18408A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868621425A GB8621425D0 (en) 1986-09-05 1986-09-05 Compounds

Publications (1)

Publication Number Publication Date
EG18408A true EG18408A (en) 1993-02-28

Family

ID=10603729

Family Applications (1)

Application Number Title Priority Date Filing Date
EG520/87A EG18408A (en) 1986-09-05 1987-09-03 Process for preparing novel substituted quinoline derivatives

Country Status (28)

Country Link
US (2) US4806549A (ko)
EP (1) EP0259174B1 (ko)
JP (1) JPH07602B2 (ko)
KR (1) KR950013850B1 (ko)
CN (1) CN1019802B (ko)
AT (1) ATE73776T1 (ko)
AU (1) AU598299B2 (ko)
CA (1) CA1308106C (ko)
CZ (1) CZ398291A3 (ko)
DE (1) DE3777505D1 (ko)
DK (1) DK159308C (ko)
EG (1) EG18408A (ko)
ES (1) ES2033316T3 (ko)
FI (1) FI88919C (ko)
GB (1) GB8621425D0 (ko)
GR (1) GR3004692T3 (ko)
HU (1) HU199804B (ko)
IE (1) IE61104B1 (ko)
IL (1) IL83691A (ko)
MX (1) MX9203550A (ko)
MY (1) MY102689A (ko)
NO (1) NO172388C (ko)
NZ (1) NZ221663A (ko)
PH (1) PH23695A (ko)
PT (1) PT85651B (ko)
WO (1) WO1988001621A1 (ko)
ZA (1) ZA876581B (ko)
ZW (1) ZW16787A1 (ko)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8610981D0 (en) * 1986-05-06 1986-06-11 Ici America Inc Quinoline amides
US4789678A (en) * 1986-08-25 1988-12-06 Hoechst-Roussel Pharmaceuticals, Inc. Memory enhancing α-alkyl-4-amino-3-quinolinemethanols and 1-(4-aralkylamino-3-quinolinyl)alkanones and related compounds
GB8804448D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804445D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
US5049567A (en) * 1988-02-25 1991-09-17 Smithkline Beckman Intercredit B.V. Substituted 4-aminoquinazoline derivatives and method of use
GB8804446D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804444D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804447D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804443D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
DK273689A (da) * 1988-06-06 1989-12-07 Sanofi Sa 4-amino-3-carboxyquinoliner og -naphthyridiner, fremgangsmaade til deres fremstilling og anvendelse deraf i laegemidler
FR2632305B1 (fr) * 1988-06-06 1992-05-15 Sanofi Sa Amino-4 aroyl-3 quinoleines et naphtyridines, leur procede de preparation et leur application en therapeutique
CA2011086A1 (en) * 1989-03-17 1990-09-17 Karl-Heinz Geiss 2-alkyl-4-arylmethylaminoquinolines, the use thereof and drugs prepared therefrom
GB8918265D0 (en) * 1989-08-10 1989-09-20 Smithkline Beckman Intercredit Compounds
AU634880B2 (en) * 1990-03-28 1993-03-04 Otsuka Pharmaceutical Co., Ltd. Quinoline derivative, antiulcer drug containing the same, and production of said derivative
GB9126438D0 (en) * 1991-12-12 1992-02-12 Smithkline Beecham Intercredit New quinoline derivatives
US5493027A (en) * 1993-01-22 1996-02-20 Board Of Regents, The University Of Texas System Anticonvulsive agents and uses thereof
US5362743A (en) * 1993-03-09 1994-11-08 Pfizer Inc. Aminoquinoline derivatives
IS4164A (is) * 1993-06-11 1994-12-12 Ab Astra Efnasambönd sem hindra flæði magasýru
US5556863A (en) * 1993-06-11 1996-09-17 Astra Aktiebolag Compound for gastric acid secretion inhibition
SE9302005D0 (sv) 1993-06-11 1993-06-11 Ab Astra New active compounds
US5650415A (en) * 1995-06-07 1997-07-22 Sugen, Inc. Quinoline compounds
IN188411B (ko) * 1997-03-27 2002-09-21 Yuhan Corp
US6852739B1 (en) * 1999-02-26 2005-02-08 Nitromed Inc. Methods using proton pump inhibitors and nitric oxide donors
GB2396815B (en) * 1999-10-27 2004-09-08 Phytopharm Plc A composition comprising a pregnenone derivative and an NSAID
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
AU2002342917A1 (en) * 2001-11-19 2003-06-10 Altana Pharma Ag Reversible proton pump inhibitors for the treatment of airway disorders
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
RS95304A (en) * 2002-05-07 2006-12-15 Altana Pharma Ag. New combination fortreating airway disorders
CA2493618A1 (en) * 2002-08-01 2004-02-12 Nitromed, Inc. Nitrosated proton pump inhibitors, compositions and methods of use
CA2503290C (en) 2003-03-10 2012-12-04 Altana Pharma Ag Novel process for the preparation of roflumilast
CN1874772A (zh) 2003-11-03 2006-12-06 阿斯利康(瑞典)有限公司 治疗隐匿性胃食管反流的咪唑并[1,2－a]吡啶衍生物
SE0400284D0 (sv) * 2004-02-10 2004-02-10 Astrazeneca Ab Novel compounds
CA2601250C (en) * 2005-03-16 2014-10-28 Nycomed Gmbh Taste masked dosage form containing roflumilast
US7803817B2 (en) 2005-05-11 2010-09-28 Vecta, Ltd. Composition and methods for inhibiting gastric acid secretion
US7981908B2 (en) 2005-05-11 2011-07-19 Vecta, Ltd. Compositions and methods for inhibiting gastric acid secretion
CA2658804A1 (en) 2006-07-25 2008-01-31 Vecta Ltd. Compositions and methods for inhibiting gastric acid secretion using derivatives of small dicarboxylic acids in combination with ppi
WO2008057802A2 (en) 2006-10-27 2008-05-15 The Curators Of The University Of Missouri Compositions comprising at least one acid labile proton pump inhibiting agents, optionally other pharmaceutically active agents and methods of using same
TW200829555A (en) * 2006-11-10 2008-07-16 Astrazeneca Ab Chemical compounds
CL2008000191A1 (es) * 2007-01-25 2008-08-22 Astrazeneca Ab Compuestos derivados de 4-amino-cinnotina-3-carboxamida; inhibidores de csf-1r quinasa; su proceso de preparacion; y su uso para tratar el cancer.
CN101980700A (zh) 2008-02-20 2011-02-23 密苏里大学董事会 包含奥美拉唑和兰索拉唑以及缓冲剂的组合的组合物及其使用方法
UY31812A (es) * 2008-05-07 2010-01-05 Astrazeneca Ab Derivados de cinolina como inhibidores de csf-1
US8247280B2 (en) 2009-10-20 2012-08-21 Taiwan Semiconductor Manufacturing Company, Ltd. Integration of low and high voltage CMOS devices
US20210177827A1 (en) * 2017-10-25 2021-06-17 Children`S Medical Center Corporation Papd5 inhibitors and methods of use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4343804A (en) * 1979-03-26 1982-08-10 A. H. Robins Company, Inc. 4-Amino-3-quinolinecarboxylic acids and esters-antisecretory anti-ulcer compounds
JO1406B1 (en) * 1984-11-02 1986-11-30 سميث كلاين اند فرينش لابوراتوريز ليمتد Chemical compounds
PH22302A (en) * 1985-02-11 1988-07-22 Fujisawa Pharmaceutical Co Piperidine compounds
EP0193329A3 (en) * 1985-02-22 1987-08-19 Beecham Group Plc Pyrazolopyridines, their preparation and pharmaceutical compositions containing them
US4789678A (en) * 1986-08-25 1988-12-06 Hoechst-Roussel Pharmaceuticals, Inc. Memory enhancing α-alkyl-4-amino-3-quinolinemethanols and 1-(4-aralkylamino-3-quinolinyl)alkanones and related compounds

Also Published As

Publication number Publication date
KR880701711A (ko) 1988-11-04
US4806550A (en) 1989-02-21
IE61104B1 (en) 1994-10-05
FI882089A0 (fi) 1988-05-04
DE3777505D1 (de) 1992-04-23
JPH07602B2 (ja) 1995-01-11
NO172388B (no) 1993-04-05
MY102689A (en) 1992-09-30
AU7874187A (en) 1988-03-24
IL83691A (en) 1993-08-18
ATE73776T1 (de) 1992-04-15
DK245888A (da) 1988-05-05
ZW16787A1 (en) 1988-05-25
CN1019802B (zh) 1992-12-30
CA1308106C (en) 1992-09-29
FI88919C (fi) 1993-07-26
GB8621425D0 (en) 1986-10-15
DK159308B (da) 1990-10-01
ES2033316T3 (es) 1993-03-16
CN87106163A (zh) 1988-03-16
NO172388C (no) 1993-07-14
DK159308C (da) 1991-03-11
NZ221663A (en) 1989-08-29
PT85651A (en) 1987-10-01
KR950013850B1 (ko) 1995-11-17
AU598299B2 (en) 1990-06-21
PH23695A (en) 1989-09-27
NO881940L (no) 1988-05-04
FI882089A (fi) 1988-05-04
IE872370L (en) 1988-03-05
GR3004692T3 (ko) 1993-04-28
CZ398291A3 (en) 1994-02-16
FI88919B (fi) 1993-04-15
EP0259174A1 (en) 1988-03-09
US4806549A (en) 1989-02-21
JPH01500664A (ja) 1989-03-09
DK245888D0 (da) 1988-05-05
PT85651B (pt) 1990-05-31
HU199804B (en) 1990-03-28
EP0259174B1 (en) 1992-03-18
HUT47913A (en) 1989-04-28
WO1988001621A1 (en) 1988-03-10
NO881940D0 (no) 1988-05-04
ZA876581B (en) 1989-04-26
MX9203550A (es) 1992-09-01

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