EG15009A - Process for preparing 4-amino-3-quinolinecarboxylic acids and esters-antisecretory;anti-ulcer compounds - Google Patents

Process for preparing 4-amino-3-quinolinecarboxylic acids and esters-antisecretory;anti-ulcer compounds

Info

Publication number
EG15009A
EG15009A EG80174A EG17480A EG15009A EG 15009 A EG15009 A EG 15009A EG 80174 A EG80174 A EG 80174A EG 17480 A EG17480 A EG 17480A EG 15009 A EG15009 A EG 15009A
Authority
EG
Egypt
Prior art keywords
antisecretory
esters
amino
preparing
quinolinecarboxylic acids
Prior art date
Application number
EG80174A
Other languages
English (en)
Inventor
Randal Harry
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Application granted granted Critical
Publication of EG15009A publication Critical patent/EG15009A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EG80174A 1979-03-26 1980-03-25 Process for preparing 4-amino-3-quinolinecarboxylic acids and esters-antisecretory;anti-ulcer compounds EG15009A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2398179A 1979-03-26 1979-03-26
US06/127,153 US4343804A (en) 1979-03-26 1980-03-04 4-Amino-3-quinolinecarboxylic acids and esters-antisecretory anti-ulcer compounds

Publications (1)

Publication Number Publication Date
EG15009A true EG15009A (en) 1985-03-31

Family

ID=26697875

Family Applications (1)

Application Number Title Priority Date Filing Date
EG80174A EG15009A (en) 1979-03-26 1980-03-25 Process for preparing 4-amino-3-quinolinecarboxylic acids and esters-antisecretory;anti-ulcer compounds

Country Status (31)

Country Link
US (1) US4343804A (es)
JP (1) JPH02117663A (es)
AR (1) AR230268A1 (es)
AT (1) AT372373B (es)
AU (1) AU528388B2 (es)
BR (1) BR8001779A (es)
CA (1) CA1147338A (es)
CH (1) CH644105A5 (es)
DE (1) DE3011490A1 (es)
DK (1) DK156056C (es)
EG (1) EG15009A (es)
ES (1) ES8103048A1 (es)
FI (1) FI77452C (es)
FR (1) FR2452485B1 (es)
GB (1) GB2047244B (es)
GR (1) GR68006B (es)
HK (1) HK67983A (es)
IE (1) IE49577B1 (es)
IL (1) IL59628A (es)
IN (1) IN151446B (es)
IT (1) IT1133079B (es)
MX (1) MX6264E (es)
NL (1) NL8001752A (es)
NO (1) NO153927C (es)
NZ (1) NZ193252A (es)
PH (1) PH16416A (es)
PL (1) PL125030B1 (es)
PT (1) PT71008B (es)
SE (1) SE435837B (es)
SG (1) SG33683G (es)
YU (1) YU41702B (es)

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GB8610981D0 (en) * 1986-05-06 1986-06-11 Ici America Inc Quinoline amides
GB8621425D0 (en) * 1986-09-05 1986-10-15 Smith Kline French Lab Compounds
GB8804443D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804448D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804446D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804447D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804444D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804445D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
US5432182A (en) * 1989-02-23 1995-07-11 Smithkline Beecham Intercredit B.V. Compounds substituted quinoline derivatives
CA2011086A1 (en) * 1989-03-17 1990-09-17 Karl-Heinz Geiss 2-alkyl-4-arylmethylaminoquinolines, the use thereof and drugs prepared therefrom
DE3917233A1 (de) * 1989-05-26 1990-11-29 Basf Ag 8-substituierte 4-(heterocyclylmethylamino)-chinoline, ihre verwendung und daraus hergestellte arzneimittel
GB8918265D0 (en) * 1989-08-10 1989-09-20 Smithkline Beckman Intercredit Compounds
US5362743A (en) * 1993-03-09 1994-11-08 Pfizer Inc. Aminoquinoline derivatives
US5556863A (en) * 1993-06-11 1996-09-17 Astra Aktiebolag Compound for gastric acid secretion inhibition
IS4164A (is) * 1993-06-11 1994-12-12 Ab Astra Efnasambönd sem hindra flæði magasýru
PT720601E (pt) * 1993-08-10 2001-02-28 Black James Foundation Ligandos de receptores de gastrina e cck
US5650415A (en) * 1995-06-07 1997-07-22 Sugen, Inc. Quinoline compounds
KR0169813B1 (ko) * 1995-07-12 1999-01-15 김종인 4-아미노-3-아실나프티리딘 유도체
US5760041A (en) * 1996-02-05 1998-06-02 American Cyanamid Company 4-aminoquinazoline EGFR Inhibitors
US6875769B2 (en) * 1996-05-23 2005-04-05 Pfizer Inc. Substituted6,6-hetero-bicyclicderivatives
US5929080A (en) * 1997-05-06 1999-07-27 American Cyanamid Company Method of treating polycystic kidney disease
US6251912B1 (en) 1997-08-01 2001-06-26 American Cyanamid Company Substituted quinazoline derivatives
US6323209B1 (en) 1997-11-06 2001-11-27 American Cyanamid Company Method of treating or inhibiting colonic polyps
CN1144786C (zh) 1998-09-29 2004-04-07 美国氰胺公司 作为蛋白质酪氨酸激酶抑制剂的取代的3-氰基喹啉
NZ519380A (en) * 1999-12-28 2004-10-29 Eisai Co Ltd Heterocyclic compounds having sulfonamide groups
US6521618B2 (en) 2000-03-28 2003-02-18 Wyeth 3-cyanoquinolines, 3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors
US6576644B2 (en) * 2000-09-06 2003-06-10 Bristol-Myers Squibb Co. Quinoline inhibitors of cGMP phosphodiesterase
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
MY140561A (en) * 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
PL377847A1 (pl) 2003-01-14 2006-02-20 Arena Pharmaceuticals Inc. 1,2,3-Tripodstawione pochodne arylowe i heteroarylowe jako modulatory metabolizmu oraz profilaktyka i leczenie związanych z nim zaburzeń takich jak cukrzyca i hiperglikemia
ME00524B (me) 2003-03-10 2011-10-10 Astrazeneca Ab Novi postupak za dobijanje roflumilasta
EA010023B1 (ru) * 2003-07-14 2008-06-30 Арена Фармасьютикалз, Инк. Конденсированные арильные и гетероарильные производные в качестве модуляторов метаболизма и для профилактики и лечения расстройств, связанных с нарушением метаболизма
JP5383183B2 (ja) * 2005-03-16 2014-01-08 タケダ ゲゼルシャフト ミット ベシュレンクテル ハフツング ロフルミラストを含有する矯味された剤形
WO2011022216A1 (en) * 2009-08-17 2011-02-24 High Point Pharmaceuticals, Llc Substituted pyridine derivatives, pharmaceutical compositions, and methods of use to treat oxidative stress
EP3378854B1 (en) 2010-01-27 2022-12-21 Arena Pharmaceuticals, Inc. Processes for the preparation of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid and salts thereof
BR112013008100A2 (pt) 2010-09-22 2016-08-09 Arena Pharm Inc "moduladores do receptor de gpr19 e o tratamento de distúrbios relacionados a eles."
AU2016205361C1 (en) 2015-01-06 2021-04-08 Arena Pharmaceuticals, Inc. Methods of treating conditions related to the S1P1 receptor
SI3310760T1 (sl) 2015-06-22 2023-02-28 Arena Pharmaceuticals, Inc. Kristalinična L-argininska sol (R)-2-(7-(4-ciklopentil-3-(trifluorometil)benziloksi)-1,2,3,4- tetrahidrociklo-penta(b)indol-3-il)ocetne kisline za uporabo pri motnjah, povezanih z receptorjem S1P1
JP7165129B2 (ja) * 2016-11-11 2022-11-02 バイエル・アニマル・ヘルス・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 新規な駆虫性キノリン-3-カルボキサミド誘導体
KR20190116416A (ko) 2017-02-16 2019-10-14 아레나 파마슈티칼스, 인크. 원발 담즙성 담관염을 치료하기 위한 화합물 및 방법
US20210177827A1 (en) * 2017-10-25 2021-06-17 Children`S Medical Center Corporation Papd5 inhibitors and methods of use thereof
EP3790874B1 (en) 2018-05-09 2023-03-15 Bayer Animal Health GmbH Anthelmintic quinoline derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3470186A (en) * 1967-06-02 1969-09-30 American Cyanamid Co Substituted 4-anilino-3-quinolinecarboxylic acids and esters
JPS4838712A (es) * 1971-09-18 1973-06-07

Also Published As

Publication number Publication date
PL125030B1 (en) 1983-03-31
DE3011490A1 (de) 1981-03-12
FI77452B (fi) 1988-11-30
AR230268A1 (es) 1984-03-01
SE8002292L (sv) 1980-09-27
AU5684880A (en) 1980-10-02
IT1133079B (it) 1986-07-09
FI77452C (fi) 1989-03-10
NO800858L (no) 1980-09-29
US4343804A (en) 1982-08-10
ES489887A0 (es) 1981-02-16
JPH02117663A (ja) 1990-05-02
FI800910A (fi) 1980-09-27
CA1147338A (en) 1983-05-31
IL59628A0 (en) 1980-06-30
CH644105A5 (fr) 1984-07-13
ES8103048A1 (es) 1981-02-16
IL59628A (en) 1983-06-15
SG33683G (en) 1985-03-29
MX6264E (es) 1985-02-19
HK67983A (en) 1983-12-23
GR68006B (es) 1981-10-26
NL8001752A (nl) 1980-09-30
IE49577B1 (en) 1985-10-30
NO153927B (no) 1986-03-10
YU41702B (en) 1987-12-31
NO153927C (no) 1986-06-18
FR2452485A1 (fr) 1980-10-24
FR2452485B1 (fr) 1986-09-12
IN151446B (es) 1983-04-23
IE800605L (en) 1980-09-26
BR8001779A (pt) 1980-11-18
PH16416A (en) 1983-09-29
NZ193252A (en) 1984-04-27
YU84480A (en) 1983-10-31
DK156056B (da) 1989-06-19
AT372373B (de) 1983-09-26
DK128380A (da) 1980-09-27
AU528388B2 (en) 1983-04-28
DK156056C (da) 1989-11-06
GB2047244B (en) 1983-02-23
ATA156480A (de) 1983-02-15
GB2047244A (en) 1980-11-26
SE435837B (sv) 1984-10-22
PT71008A (en) 1980-04-01
IT8067465A0 (it) 1980-03-26
DE3011490C2 (es) 1988-12-22
PL222993A1 (es) 1981-01-30
PT71008B (en) 1981-06-25

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