EE05458B1 - CTL4 lahustuvad mutantsed molekulid ja nende kasutamine - Google Patents

CTL4 lahustuvad mutantsed molekulid ja nende kasutamine

Info

Publication number
EE05458B1
EE05458B1 EEP200200659A EEP200200659A EE05458B1 EE 05458 B1 EE05458 B1 EE 05458B1 EE P200200659 A EEP200200659 A EE P200200659A EE P200200659 A EEP200200659 A EE P200200659A EE 05458 B1 EE05458 B1 EE 05458B1
Authority
EE
Estonia
Prior art keywords
mutant molecules
amino acid
ctla4
ctl4
molecules
Prior art date
Application number
EEP200200659A
Other languages
English (en)
Estonian (et)
Inventor
J. Peach Robert
R. Naemura Joseph
S. Linsley Peter
Bajorath Jurgen
Original Assignee
Bristol-Myers Squibb Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol-Myers Squibb Company filed Critical Bristol-Myers Squibb Company
Priority to EEP201100050A priority Critical patent/EE05557B1/xx
Publication of EE200200659A publication Critical patent/EE200200659A/xx
Publication of EE05458B1 publication Critical patent/EE05458B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70521—CD28, CD152
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system
    • G01N33/505—Cells of the immune system involving T-cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Transplantation (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EEP200200659A 2000-05-26 2001-05-23 CTL4 lahustuvad mutantsed molekulid ja nende kasutamine EE05458B1 (et)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EEP201100050A EE05557B1 (et) 2000-05-26 2001-05-23 CTL4 lahustuvad mutantsed molekulid ja nende kasutamine

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US57992700A 2000-05-26 2000-05-26
US21406500P 2000-06-26 2000-06-26
PCT/US2001/017139 WO2001092337A2 (en) 2000-05-26 2001-05-23 Soluble ctla4 mutant molecules and uses thereof

Publications (2)

Publication Number Publication Date
EE200200659A EE200200659A (et) 2004-06-15
EE05458B1 true EE05458B1 (et) 2011-08-15

Family

ID=26908652

Family Applications (2)

Application Number Title Priority Date Filing Date
EEP200200659A EE05458B1 (et) 2000-05-26 2001-05-23 CTL4 lahustuvad mutantsed molekulid ja nende kasutamine
EEP201100050A EE05557B1 (et) 2000-05-26 2001-05-23 CTL4 lahustuvad mutantsed molekulid ja nende kasutamine

Family Applications After (1)

Application Number Title Priority Date Filing Date
EEP201100050A EE05557B1 (et) 2000-05-26 2001-05-23 CTL4 lahustuvad mutantsed molekulid ja nende kasutamine

Country Status (41)

Country Link
EP (3) EP3029062A1 (sr)
JP (1) JP4328525B2 (sr)
KR (2) KR100889887B1 (sr)
CN (2) CN101255192A (sr)
AR (1) AR031699A1 (sr)
AT (1) ATE271066T1 (sr)
AU (2) AU6346601A (sr)
BE (1) BE2011C041I2 (sr)
BR (1) BRPI0111191B8 (sr)
CA (1) CA2409748C (sr)
CY (2) CY2011019I1 (sr)
CZ (1) CZ304451B6 (sr)
DE (2) DE60104282T2 (sr)
DK (1) DK1248802T3 (sr)
EC (1) ECSP024365A (sr)
EE (2) EE05458B1 (sr)
EG (1) EG24459A (sr)
ES (2) ES2225549T3 (sr)
FR (1) FR11C0053I2 (sr)
GE (1) GEP20053658B (sr)
HK (1) HK1048126B (sr)
HU (2) HU228137B1 (sr)
IL (1) IL152315A (sr)
LT (1) LT5133B (sr)
LU (1) LU91902I2 (sr)
LV (1) LV12994B (sr)
MX (1) MXPA02011534A (sr)
MY (1) MY136113A (sr)
NO (2) NO330797B1 (sr)
PE (1) PE20011338A1 (sr)
PL (1) PL206267B1 (sr)
PT (1) PT1248802E (sr)
RU (1) RU2283847C2 (sr)
SI (1) SI1248802T1 (sr)
SK (1) SK288131B6 (sr)
TR (1) TR200402703T4 (sr)
TW (2) TWI314933B (sr)
UA (1) UA87432C2 (sr)
UY (1) UY26723A1 (sr)
WO (1) WO2001092337A2 (sr)
ZA (1) ZA200208944B (sr)

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BR112016015797B1 (pt) 2014-01-13 2022-10-11 Amgen Inc Método para diminuir o teor de glicoforma de alta manose de uma proteína recombinante e método de produção de uma proteína recombinante
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Also Published As

Publication number Publication date
CY1117625T1 (el) 2017-04-26
SK288131B6 (sk) 2013-10-02
WO2001092337A3 (en) 2002-05-10
EP1536234B1 (en) 2016-03-16
NO330797B1 (no) 2011-07-18
CA2409748C (en) 2008-09-16
ATE271066T1 (de) 2004-07-15
KR20070094019A (ko) 2007-09-19
LU91902I2 (fr) 2012-01-16
AR031699A1 (es) 2003-10-01
NO20025656D0 (no) 2002-11-25
NO2011027I1 (no) 2012-01-09
NO20025656L (no) 2002-11-25
MY136113A (en) 2008-08-29
HUP0302201A3 (en) 2010-01-28
EE05557B1 (et) 2012-08-15
UY26723A1 (es) 2001-12-28
BRPI0111191B8 (pt) 2021-05-25
JP2004511213A (ja) 2004-04-15
IL152315A0 (en) 2003-05-29
DK1248802T3 (da) 2004-11-15
PE20011338A1 (es) 2002-01-13
CN1441810A (zh) 2003-09-10
CN1309735C (zh) 2007-04-11
TWI314933B (en) 2009-09-21
CA2409748A1 (en) 2001-12-06
JP4328525B2 (ja) 2009-09-09
CZ304451B6 (cs) 2014-05-14
TWI319405B (en) 2010-01-11
TR200402703T4 (tr) 2004-11-22
BE2011C041I2 (sr) 2020-08-20
SI1248802T1 (en) 2005-02-28
DE60104282T2 (de) 2005-10-13
KR20030009502A (ko) 2003-01-29
DE122011100063I1 (de) 2012-06-14
EP1248802B9 (en) 2005-05-11
HK1071931A1 (en) 2005-08-05
AU2001263466B2 (en) 2006-04-27
AU2001263466C1 (en) 2006-10-26
UA87432C2 (uk) 2009-07-27
ZA200208944B (en) 2004-02-13
FR11C0053I1 (sr) 2012-01-13
HK1048126A1 (en) 2003-03-21
LV12994B (en) 2003-08-20
CY2011019I2 (el) 2016-12-14
NO2011027I2 (sr) 2011-12-15
PL206267B1 (pl) 2010-07-30
KR100895134B1 (ko) 2009-05-04
CN101255192A (zh) 2008-09-03
HUP0302201A2 (hu) 2003-10-28
IL152315A (en) 2010-04-15
SK15702002A3 (sk) 2004-01-08
PT1248802E (pt) 2004-11-30
CZ20023892A3 (cs) 2003-09-17
BR0111191A (pt) 2004-07-06
CY2011019I1 (el) 2016-12-14
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FR11C0053I2 (fr) 2013-01-11
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