EE05183B1 - Asabitsklilised hendid, nende valmistamine ja kasutamine ravimitena ning neid sisaldav farmatseutiline kompositsioon - Google Patents
Asabitsklilised hendid, nende valmistamine ja kasutamine ravimitena ning neid sisaldav farmatseutiline kompositsioonInfo
- Publication number
- EE05183B1 EE05183B1 EEP200300046A EEP200300046A EE05183B1 EE 05183 B1 EE05183 B1 EE 05183B1 EE P200300046 A EEP200300046 A EE P200300046A EE P200300046 A EEP200300046 A EE P200300046A EE 05183 B1 EE05183 B1 EE 05183B1
- Authority
- EE
- Estonia
- Prior art keywords
- azabitic
- pharmaceuticals
- compounds
- preparation
- pharmaceutical composition
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0010121A FR2812635B1 (fr) | 2000-08-01 | 2000-08-01 | Nouveaux composes heterocycliques, preparation et utilisation comme medicaments notamment comme anti- bacteriens |
PCT/FR2001/002418 WO2002010172A1 (fr) | 2000-08-01 | 2001-07-24 | Composes azabicycliques, leur preparation et leur utilisation comme medicaments, notamment comme anti-bacteriens |
Publications (2)
Publication Number | Publication Date |
---|---|
EE200300046A EE200300046A (et) | 2004-10-15 |
EE05183B1 true EE05183B1 (et) | 2009-06-15 |
Family
ID=8853181
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EEP200300046A EE05183B1 (et) | 2000-08-01 | 2001-07-24 | Asabitsklilised hendid, nende valmistamine ja kasutamine ravimitena ning neid sisaldav farmatseutiline kompositsioon |
Country Status (42)
Country | Link |
---|---|
US (5) | US7112592B2 (es) |
EP (1) | EP1307457B1 (es) |
JP (2) | JP4515704B2 (es) |
KR (1) | KR100632906B1 (es) |
CN (1) | CN1289500C (es) |
AP (1) | AP1614A (es) |
AR (1) | AR031716A1 (es) |
AT (1) | ATE263768T1 (es) |
AU (2) | AU2001279905B2 (es) |
BG (1) | BG66094B1 (es) |
BR (1) | BRPI0112986B8 (es) |
CA (1) | CA2417475C (es) |
CR (1) | CR6895A (es) |
CZ (1) | CZ294956B6 (es) |
DE (1) | DE60102702T2 (es) |
DK (1) | DK1307457T3 (es) |
DZ (1) | DZ3397A1 (es) |
EA (1) | EA004920B1 (es) |
EC (1) | ECSP034460A (es) |
EE (1) | EE05183B1 (es) |
ES (1) | ES2220793T3 (es) |
FR (1) | FR2812635B1 (es) |
HK (1) | HK1060356A1 (es) |
HR (1) | HRP20030034B1 (es) |
HU (1) | HU226889B1 (es) |
IL (2) | IL154187A0 (es) |
MA (1) | MA26938A1 (es) |
ME (2) | ME00060B (es) |
MX (1) | MXPA03000881A (es) |
NO (1) | NO324940B1 (es) |
NZ (1) | NZ523707A (es) |
OA (1) | OA12347A (es) |
PL (2) | PL234468B1 (es) |
PT (1) | PT1307457E (es) |
RS (1) | RS50214B (es) |
SI (1) | SI1307457T1 (es) |
SK (1) | SK287597B6 (es) |
TR (1) | TR200400859T4 (es) |
TW (1) | TWI292401B (es) |
UA (1) | UA73791C2 (es) |
WO (1) | WO2002010172A1 (es) |
ZA (1) | ZA200300676B (es) |
Families Citing this family (95)
Publication number | Priority date | Publication date | Assignee | Title |
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FR2812635B1 (fr) * | 2000-08-01 | 2002-10-11 | Aventis Pharma Sa | Nouveaux composes heterocycliques, preparation et utilisation comme medicaments notamment comme anti- bacteriens |
FR2835186B1 (fr) * | 2002-01-28 | 2006-10-20 | Aventis Pharma Sa | Nouveaux composes heterocycliques, actifs comme inhibiteurs de beta-lactamases |
FR2844273B1 (fr) | 2002-09-05 | 2008-04-04 | Aventis Pharma Sa | Nouveaux composes heterocycliques, procede et intermediaires de preparation et utilisation comme medicament, notamment comme inhibiteurs de beta-lactamases et anti-bacteriens. |
US7439253B2 (en) * | 2002-12-06 | 2008-10-21 | Novexel | Heterocyclic compounds, their preparation and their use as medicaments, in particular as antibacterials and beta-lactamase inhibitors |
FR2848210B1 (fr) * | 2002-12-06 | 2007-10-19 | Aventis Pharma Sa | Nouveaux composes heterocycliques, leur preparation et leur utilisation comme medicaments, notamment comme anti-bacteriens et inhibiteurs de beta-lactamases |
CN102988362B (zh) | 2005-12-07 | 2014-11-05 | 巴斯利尔药物股份公司 | 单环-内酰胺类抗生素与β-内酰胺酶抑制剂的有效的联合应用 |
EA017448B1 (ru) | 2006-07-13 | 2012-12-28 | Ачиллион Фармасьютикалз, Инк. | 4-амино-4-оксобутаноиловые пептиды как ингибиторы вирусной репликации |
US20090298878A1 (en) * | 2006-07-14 | 2009-12-03 | Akira Matsumura | Oxime compounds and the use thereof |
AU2007300531A1 (en) * | 2006-09-27 | 2008-04-03 | Merck Sharp & Dohme Corp. | Novel inhibitors of beta-lactamase |
KR20090064463A (ko) * | 2006-10-23 | 2009-06-18 | 아이알엠 엘엘씨 | 카텝신 프로테아제 억제제 |
EP2119702A4 (en) | 2007-01-31 | 2010-12-08 | Dainippon Sumitomo Pharma Co | amide derivative |
FR2914923B1 (fr) * | 2007-04-12 | 2013-06-14 | Novexel | Nouveaux composes heterocycliques azotes,leur preparation et leur utilisation comme medicaments antibacteriens. |
JP5323063B2 (ja) * | 2007-05-31 | 2013-10-23 | 塩野義製薬株式会社 | オキシイミノ化合物およびその使用 |
FR2921060B1 (fr) * | 2007-09-14 | 2012-06-15 | Novexel | Nouveau procede de preparation d'une piperidine disubsituee et nouveaux intermediaires |
ES2533826T3 (es) * | 2008-01-18 | 2015-04-15 | Merck Sharp & Dohme Corp. | Inhibidores de beta-lactamasa |
EP2346820B1 (en) | 2008-06-11 | 2013-02-13 | Shionogi & Co., Ltd. | Oxycarbamoyl compounds and the use thereof |
EP2135959A1 (en) | 2008-06-19 | 2009-12-23 | Novexel | Use of (1R,2S,5R) 1,6-Diazabicyclo [3,2,1]octane-2-carboxamide, 7-oxo-6-(sulfooxy)-, monosodium salt as a diagnostic reagent for detecting serine beta-lactamases |
FR2936798B1 (fr) * | 2008-10-03 | 2012-09-28 | Novexel | Nouveaux composes heterocycliques azotes, leur preparation et leur utilisation comme medicaments antibacteriens. |
FR2937034B1 (fr) | 2008-10-10 | 2012-11-23 | Novexel | Nouveaux composes heterocycliques azotes, leur preparation et leur utilisation comme medicaments antibacteriens |
US20120053350A1 (en) * | 2009-04-30 | 2012-03-01 | Ian Mangion | Preparation of alkyl esters of n-protected oxo-azacycloalkylcarboxylic acids |
EP2447264A4 (en) | 2009-06-24 | 2012-12-12 | Dainippon Sumitomo Pharma Co | N-SUBSTITUTED CYCLIC AMINO DERIVATIVE |
FR2951171A1 (fr) | 2009-10-09 | 2011-04-15 | Novexel | Nouveau sel de sodium d'un compose azabicyclique sous forme enantiomere cristallisee et nouvelles formes polymorphes et pseudopolymorphes ainsi que leur preparation |
CA2822758C (en) * | 2010-12-22 | 2018-03-20 | Meiji Seika Pharma Co., Ltd. | Optically active diazabicyclooctane derivative and process for preparing the same |
US8772490B2 (en) | 2010-12-22 | 2014-07-08 | Meiji Seika Pharma Co., Ltd. | Optically active diazabicyclooctane derivatives and process for preparing the same |
JP6023800B2 (ja) | 2011-06-17 | 2016-11-09 | アストラゼネカ アクチボラグ | trans−7−オキソ−6−(スルホオキシ)−1,6−ジアザビシクロ[3,2,1]オクタン−2−カルボキサミドとその塩が含まれる複素環式化合物を製造するための方法 |
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US8796257B2 (en) | 2011-12-02 | 2014-08-05 | Naeja Pharmaceutical Inc. | Bicyclic compounds and their use as antibacterial agents and β-lactamase inhibitors |
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US9512452B2 (en) | 2013-02-19 | 2016-12-06 | Api Corporation | L-lysine hydroxylase and production method for hydroxy-L-lysine and hydroxy-L-pipecolic acid using same |
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CN110078728B (zh) * | 2019-05-23 | 2020-10-23 | 江西富祥药业股份有限公司 | 一种阿维巴坦中间体、制备方法及其应用 |
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JPS4939678B1 (es) * | 1968-05-06 | 1974-10-28 | ||
US4024147A (en) * | 1972-06-30 | 1977-05-17 | John Wyeth & Brother Limited | Heterocyclic compounds |
US4049821A (en) * | 1976-05-12 | 1977-09-20 | A. H. Robins Company, Inc. | Method of treating allergy |
JPS63119471A (ja) * | 1986-09-02 | 1988-05-24 | ザ・ユニバーシテイ・オブ・メルボルン | 2−オキソ−4−カルボキシ−ピリミジン |
EP0260057A3 (en) * | 1986-09-02 | 1989-02-01 | The University Of Melbourne | 2-oxo-4-carboxy-pyrimidines |
JP2895630B2 (ja) * | 1993-12-29 | 1999-05-24 | フアイザー・インコーポレイテツド | ジアザビシクロニューロキニンアンタゴニスト |
TW358097B (en) * | 1996-05-24 | 1999-05-11 | Hoffmann La Roche | Beta-lactams and their process and pharmaceutical compositions |
HUP0001741A3 (en) * | 1996-08-02 | 2000-11-28 | Smithkline Beecham Plc | Azabicyclic carbamoyloxy mutilin derivatives for antibacterial use, process for preparing them, pharmaceuticals contg. them and their use |
SK101199A3 (en) * | 1997-02-10 | 2000-10-09 | Pfizer Prod Inc | 2-amino-6-(2-substituted-4-phenoxy)-substituted-pyridines, their use and pharmaceutical compositions based thereupon |
US6060585A (en) * | 1997-03-04 | 2000-05-09 | Wisconsin Alumni Research Foundation | β-polypeptide foldamers of well-defined secondary structure |
KR100207096B1 (ko) * | 1997-07-08 | 1999-07-15 | 이명환 | 시사프라이드의 제조 방법 |
JP2001508811A (ja) * | 1998-04-20 | 2001-07-03 | 藤沢薬品工業株式会社 | cGMP−ホスホジエステラーゼ阻害剤としてのアントラニル酸誘導体 |
GB9817029D0 (en) * | 1998-08-05 | 1998-09-30 | Smithkline Beecham Plc | Novel compounds |
FR2784682B1 (fr) * | 1998-10-15 | 2002-12-06 | Hoechst Marion Roussel Inc | Nouveaux derives 2-halogene de 5-0-desosaminylerythronolide a, leur procede de preparation et leur application comme medicaments |
ATE272633T1 (de) * | 1998-12-23 | 2004-08-15 | Lilly Co Eli | Aromatische amiden |
CA2358578A1 (en) * | 1999-01-02 | 2000-07-13 | Aventis Pharma Deutschland Gmbh | Novel malonic acid derivatives, processes for their preparation, their use and pharmaceutical compositions containing them (inhibition of factor xa activity) |
FR2812635B1 (fr) * | 2000-08-01 | 2002-10-11 | Aventis Pharma Sa | Nouveaux composes heterocycliques, preparation et utilisation comme medicaments notamment comme anti- bacteriens |
FR2835186B1 (fr) * | 2002-01-28 | 2006-10-20 | Aventis Pharma Sa | Nouveaux composes heterocycliques, actifs comme inhibiteurs de beta-lactamases |
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