EE05162B1 - Meetod optiliselt aktiivsete amiinide saamiseks - Google Patents

Meetod optiliselt aktiivsete amiinide saamiseks

Info

Publication number
EE05162B1
EE05162B1 EEP200200268A EEP200200268A EE05162B1 EE 05162 B1 EE05162 B1 EE 05162B1 EE P200200268 A EEP200200268 A EE P200200268A EE P200200268 A EEP200200268 A EE P200200268A EE 05162 B1 EE05162 B1 EE 05162B1
Authority
EE
Estonia
Prior art keywords
optically active
preparation
active amines
amines
racemic
Prior art date
Application number
EEP200200268A
Other languages
English (en)
Inventor
Ditrich Klaus
Siegel Wolfgang
Original Assignee
Basf Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Aktiengesellschaft filed Critical Basf Aktiengesellschaft
Publication of EE200200268A publication Critical patent/EE200200268A/et
Publication of EE05162B1 publication Critical patent/EE05162B1/et

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/08Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom
    • C07C217/10Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/04Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
    • C07C215/06Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
    • C07C215/08Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with only one hydroxy group and one amino group bound to the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/08Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
EEP200200268A 1999-11-25 2000-11-13 Meetod optiliselt aktiivsete amiinide saamiseks EE05162B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19956786A DE19956786A1 (de) 1999-11-25 1999-11-25 Verfahren zur Herstellung optisch aktiver Amine
PCT/EP2000/011191 WO2001038292A2 (de) 1999-11-25 2000-11-13 Verfahren zur herstellung optisch aktiver amine

Publications (2)

Publication Number Publication Date
EE200200268A EE200200268A (et) 2003-06-16
EE05162B1 true EE05162B1 (et) 2009-04-15

Family

ID=7930317

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200200268A EE05162B1 (et) 1999-11-25 2000-11-13 Meetod optiliselt aktiivsete amiinide saamiseks

Country Status (16)

Country Link
US (2) US7078226B1 (et)
EP (1) EP1232279B1 (et)
JP (1) JP4776846B2 (et)
KR (1) KR100677798B1 (et)
CN (1) CN1204262C (et)
AT (1) ATE290099T1 (et)
AU (1) AU2356101A (et)
BR (1) BR0015805B1 (et)
CA (1) CA2396661C (et)
DE (2) DE19956786A1 (et)
EE (1) EE05162B1 (et)
IL (2) IL149048A0 (et)
NO (1) NO328104B1 (et)
RU (1) RU2293724C9 (et)
UA (1) UA77651C2 (et)
WO (1) WO2001038292A2 (et)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2843112B1 (fr) * 2002-07-30 2004-10-22 Clariant Procede de preparation d'amines primaires.
GB0306267D0 (en) 2003-03-19 2003-04-23 Ineos Fluor Ltd Process
KR100739537B1 (ko) 2004-01-07 2007-07-13 주식회사 카이로라이트 카이랄 무기-유기 혼성 다공성 물질 및 이의 제조 방법
DE102005028492A1 (de) * 2005-06-20 2006-12-28 Basf Ag Verfahren zur Herstellung von optisch aktiven Aminoalkylphenolen
DE102005063192A1 (de) * 2005-12-30 2007-07-05 Basf Ag Racematspaltung von 2,6-trans-Dimethyl-morpholin
EP2099298A4 (en) * 2006-12-07 2010-01-06 Helsinn Healthcare Sa CRYSTALLINE AND AMORPHOUS FORMS OF PALONOSETRON HYDROCHLORIDE
DK2387556T3 (da) 2009-01-16 2014-11-03 Basf Se Separation af en enantiomerblanding af (r)- og (s)-3-amino-1-butanol
JP6687596B2 (ja) * 2015-02-17 2020-04-22 アモーレパシフィック コーポレーションAmorepacific Corporation N−[4−(1−アミノエチル)−フェニル]−スルホンアミド誘導体のキラル分割方法
KR102565407B1 (ko) * 2016-01-04 2023-08-10 (주)아모레퍼시픽 극성 비양자성 용매를 이용한 n-[4-(1-아미노에틸)-페닐]-술폰아미드 유도체의 카이랄 분할 방법
CN117945937B (zh) * 2024-01-26 2024-07-30 重庆华森制药股份有限公司 一种制备高光学纯度苯磺酸美洛加巴林的方法

Family Cites Families (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE247144C (et) *
GB292615A (et) * 1927-06-23 1929-07-18 I.G. Farbenindustrie Aktiengesellschaft
DE551436C (de) * 1930-08-22 1932-06-02 I G Farbenindustrie Akt Ges Verfahren zur Darstellung von Diaminen
DE723498C (de) * 1939-01-19 1942-08-18 Ig Farbenindustrie Ag Verfahren zur Herstellung von aliphatischen Oxyaldehyden und Oxyketonen
US2424061A (en) * 1944-06-29 1947-07-15 Lilly Co Eli 9-amino-alkyl-amino-substituted acridine derivatives
GB609488A (en) * 1944-08-07 1948-10-01 Lilly Co Eli Production of propyldiamines and acridine compounds of propyldiamines
GB615715A (en) * 1945-02-22 1949-01-11 Sharples Chemicals Inc Improvements in or relating to amines and process of forming same
US2624753A (en) * 1948-06-30 1953-01-06 Monsanto Chemicals 5-n-butoxy-1-hexyl adipate and method for making the same
US2764615A (en) * 1952-05-01 1956-09-25 Purdue Research Foundation Alkoxyalkylamines and acid addition salts
GB739741A (en) * 1952-11-10 1955-11-02 Lilly Co Eli Improvements in or relating to substituted benzamidopropylamines and process of preparing the same
US3009915A (en) * 1958-10-01 1961-11-21 Sahyun 1, 4, 5, 6-tetrahydro-pirimidylmethylacetates and glycolates
BE795019A (fr) * 1972-02-07 1973-08-06 Ciba Geigy Composes anthraquinoniques, leur procede de preparation et leur utilisation
DE2509155A1 (de) * 1975-03-03 1976-09-09 Hoechst Ag 1,4-benzoxazinderivate und verfahren zu ihrer herstellung
IT1083904B (it) * 1976-08-31 1985-05-25 Lilly Co Eli Composizione erbicida acquatica a base di fenossi alchilammine sostituite
US4207343A (en) * 1978-06-22 1980-06-10 Eli Lilly And Company 1-Phenyl-3-(substituted phenoxy)propylamines
DE2935062A1 (de) * 1978-09-06 1980-03-20 Degussa Substituierte aminoalkylguanidine, deren herstellung und arzneimittel
FR2496653A1 (fr) * 1980-12-22 1982-06-25 Delalande Sa Nouveaux derives aminoalcoyl heterocycliques, leurs procedes de preparation et leur application en therapeutique
HU184392B (en) * 1981-03-04 1984-08-28 Gyogyszerkutato Intezet Process for producing new alkylene-diamine derivatives
EP0097202B1 (en) * 1982-06-23 1987-11-19 Teikoku Hormone Mfg. Co., Ltd. Hydrazinopyridazine compound, process for production thereof, and use thereof as medicament
JPS61145166A (ja) * 1984-12-12 1986-07-02 バイエル・アクチエンゲゼルシヤフト 新規な2,4‐ジアミノピリジン類
JPS61171458A (ja) * 1985-01-25 1986-08-02 Tokuyama Soda Co Ltd アミン化合物の製造方法
JPS61197558A (ja) * 1985-02-25 1986-09-01 Nippon Chemiphar Co Ltd 新規なキナルジン酸アミド誘導体およびその製造法
JPS6354342A (ja) * 1986-08-26 1988-03-08 Daicel Chem Ind Ltd (±)−α−エチルベンジルアミンの光学分割方法
IL85988A (en) * 1987-04-09 1992-08-18 Lilly Co Eli 1-phenyl-3-naphthalenyloxy-propanamines,process for their preparation and pharmaceutical compositions containing them
US5039706A (en) * 1987-11-30 1991-08-13 Du Pont Merck Pharmaceutical Company Antiinflammatory PLA2 inhibitors
FI902321A0 (fi) * 1989-05-19 1990-05-09 Eisai Co Ltd Butensyraderivat.
JPH07119189B2 (ja) * 1989-09-28 1995-12-20 北陸製薬株式会社 光学活性なベンジルアルコール誘導体及びその用途
WO1991019002A1 (en) 1990-06-01 1991-12-12 Carlbiotech Ltd. A/S A process for chiral enrichment of asymmetric primary amines
US5057607A (en) 1990-06-08 1991-10-15 Eli Lilly And Company Enantiomerically selective biocatalyzed acylation
DE4232424A1 (de) * 1992-09-28 1994-03-31 Basf Ag Verfahren zur Herstellung von ungesättigten Aminen
DE4332738A1 (de) 1993-09-25 1995-03-30 Basf Ag Racematspaltung primärer und sekundärer Amine durch Enzym-katalysierte Acylierung
JP3312459B2 (ja) * 1993-12-28 2002-08-05 東レ株式会社 光学活性アミンの単離方法
PT801683E (pt) 1995-02-03 2002-09-30 Basf Ag Separacao de racematos de animais primarias e secundarias substituidas por heteroatomos por acilacao catalisada por enzimas
DE19534208A1 (de) 1995-09-15 1997-03-20 Basf Ag Spaltung von optisch aktiven Amiden
DE19535762A1 (de) * 1995-09-26 1997-03-27 Basf Ag Verfahren zur Racematspaltung
DE59608741D1 (de) 1995-12-06 2002-03-21 Bayer Ag Verfahren zur herstellung von optisch aktiven aminen
DE19603575A1 (de) * 1996-02-01 1997-08-07 Bayer Ag Verfahren zur Herstellung von optisch aktiven Aminen
US6166048A (en) * 1999-04-20 2000-12-26 Targacept, Inc. Pharmaceutical compositions for inhibition of cytokine production and secretion
DE19621686A1 (de) 1996-05-30 1997-12-04 Bayer Ag Verfahren zur Herstellung von optisch aktiven Aminen
DE19629692A1 (de) 1996-07-23 1998-01-29 Bayer Ag Verfahren zur Herstellung von racemischen Phenethylaminen
DE19727517A1 (de) * 1997-06-30 1999-01-07 Basf Ag Racematspaltung von Aminosäureestern durch Enzym-katalysierte Acylierung
WO1999016750A1 (en) * 1997-09-30 1999-04-08 Merck & Co., Inc. Thrombin inhibitors
DE19837745A1 (de) * 1998-08-20 2000-02-24 Basf Ag Enzymkatalysierte Racematspaltung von primären Aminen
BR0011534A (pt) * 1999-05-24 2002-02-26 Targacept Inc Alquilaminas aril substituìdas capazes de ativação de receptores colinérgicos nicotìnicos
AU777578B2 (en) * 1999-06-30 2004-10-21 Regents Of The University Of California, The Hexahydropyrrolo(1,2-C)pyrimidines as antiviral, antifungal and/or antitumor agents

Also Published As

Publication number Publication date
NO20022458D0 (no) 2002-05-24
US7358396B2 (en) 2008-04-15
CA2396661C (en) 2010-10-19
DE50009670D1 (de) 2005-04-07
BR0015805B1 (pt) 2013-04-30
IL149048A0 (en) 2002-11-10
EP1232279A2 (de) 2002-08-21
ATE290099T1 (de) 2005-03-15
RU2293724C2 (ru) 2007-02-20
CA2396661A1 (en) 2001-05-31
DE19956786A1 (de) 2001-05-31
EE200200268A (et) 2003-06-16
CN1204262C (zh) 2005-06-01
US7078226B1 (en) 2006-07-18
WO2001038292A2 (de) 2001-05-31
RU2293724C9 (ru) 2008-06-27
EP1232279B1 (de) 2005-03-02
NO20022458L (no) 2002-05-24
RU2002117053A (ru) 2004-01-20
US20060122429A1 (en) 2006-06-08
JP2003514888A (ja) 2003-04-22
KR100677798B1 (ko) 2007-02-05
WO2001038292A3 (de) 2002-02-28
UA77651C2 (en) 2007-01-15
JP4776846B2 (ja) 2011-09-21
NO328104B1 (no) 2009-12-07
IL149048A (en) 2007-03-08
KR20020051937A (ko) 2002-06-29
BR0015805A (pt) 2002-08-06
AU2356101A (en) 2001-06-04
CN1399687A (zh) 2003-02-26

Similar Documents

Publication Publication Date Title
ATE292959T1 (de) Verfahren zur herstellung von pankreasenzym enthaltende mikrosphären mit hoher stabilität
EA200001129A2 (ru) Способ получения 4-карбоксиамино-2-замещенного-1,2,3,4-тетрагидрохинолина
EE05162B1 (et) Meetod optiliselt aktiivsete amiinide saamiseks
DE60034885D1 (de) Enzymlauge und verfahren zu deren herstellung, enzymzubereitung, proteasezubereitungen und proteaseproduzierendes bakterium
AU7593701A (en) 5-trityloxymethyl-oxazolidinones and process for the preparation thereof
HUP0303926A3 (en) Process for the production of l-amino acids by fermentation using coryneform bacteria
ZA200001354B (en) Process for the production of L-amino acids by fermentation using coryneform bacteria.
DK0786012T3 (da) Enzymatisk fremgangsmåde til fremstilling af kiral-alfa-tertiære carboxylsyreestere
HUP0103764A2 (en) Process for producing non-proteinogenic amino acids by fermentation, and l-amino acids obtained by said process
CA2150526A1 (en) Biotechnological process for the preparation of cyclic s-.alpha.-amino carboxylic acids and r-.alpha.-amino carboxamides
MXPA02004829A (es) Metodo para la sintesis estereoselectiva de aminoacidos ciclicos.
AU4039799A (en) Method for the racemization of optically active amines
HUP0201850A2 (en) Method for the production of l-amino acids from their racemic n-acetyl-d,l-derivatives by enzymatic racemate cleavage by means of isolated recombinant enzymes
DE50213120D1 (de) Mikrobiologisches verfahren zur herstellung von amiden
FI19992095A (fi) Menetelmä ja entsyymivalmiste prosessiteollisuuteen
PT1140794E (pt) Novo processo de preparacao de aminoacidos quirais
DE60012802D1 (de) Verfahren zur Herstellung von optisch aktiven Cyanhydrinen
DK1001929T3 (da) Fremgangsmåde til fremstilling af 3-cyano-2,4-dihalogen-5-flour-benzoesyrer
IT1307976B1 (it) Processo per la preparazione di acidi benzofenonsolfonici.
AU2003215640A1 (en) Process for preparing optically active beta-aminocarboxylic acids from racemic n-acylated beta-aminocarboxylic acids
IL149891A0 (en) Method for the production of optically active cyanohydrins using r-oxynitrilase
MY127965A (en) Enzymatic process for the enantiomeric resolution of amino acids
SI1238094T1 (en) Method for the production of optically active cyanohydrins using r-oxynitrilase
DE60101351T2 (de) Verfahren zur herstellung optisch aktiver, n-substituierter azetidin-2-carbonsäuren
AU1838900A (en) Process for preparing optically active alpha-hydroxy acids and derivatives thereof

Legal Events

Date Code Title Description
KB4A Valid patent at the end of a year

Effective date: 20101231