DK0786012T3 - Enzymatisk fremgangsmåde til fremstilling af kiral-alfa-tertiære carboxylsyreestere - Google Patents

Enzymatisk fremgangsmåde til fremstilling af kiral-alfa-tertiære carboxylsyreestere

Info

Publication number
DK0786012T3
DK0786012T3 DK95936341T DK95936341T DK0786012T3 DK 0786012 T3 DK0786012 T3 DK 0786012T3 DK 95936341 T DK95936341 T DK 95936341T DK 95936341 T DK95936341 T DK 95936341T DK 0786012 T3 DK0786012 T3 DK 0786012T3
Authority
DK
Denmark
Prior art keywords
carboxylic acid
acid esters
enzymatic process
tertiary carboxylic
preparing chiral
Prior art date
Application number
DK95936341T
Other languages
English (en)
Inventor
Fateme Sima Sariaslani
Barry Stieglitz
Vincent G Witterholt
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/457,891 external-priority patent/US5580783A/en
Application filed by Du Pont filed Critical Du Pont
Application granted granted Critical
Publication of DK0786012T3 publication Critical patent/DK0786012T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/005—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK95936341T 1994-10-12 1995-10-04 Enzymatisk fremgangsmåde til fremstilling af kiral-alfa-tertiære carboxylsyreestere DK0786012T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US32149694A 1994-10-12 1994-10-12
US08/457,891 US5580783A (en) 1994-10-12 1995-06-01 Enzymatic process for the preparation of chiral α-tertiary carboxylic acid esters
PCT/US1995/013225 WO1996012035A1 (en) 1994-10-12 1995-10-04 Enzymatic process for the preparation of chiral-alpha-tertiary carboxylic acid esters

Publications (1)

Publication Number Publication Date
DK0786012T3 true DK0786012T3 (da) 1999-08-23

Family

ID=26982998

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95936341T DK0786012T3 (da) 1994-10-12 1995-10-04 Enzymatisk fremgangsmåde til fremstilling af kiral-alfa-tertiære carboxylsyreestere

Country Status (10)

Country Link
EP (1) EP0786012B1 (da)
JP (1) JP3794702B2 (da)
CN (1) CN1160421A (da)
AU (1) AU3832995A (da)
CZ (1) CZ111197A3 (da)
DE (1) DE69506900T2 (da)
DK (1) DK0786012T3 (da)
ES (1) ES2128093T3 (da)
IL (1) IL115594A (da)
WO (1) WO1996012035A1 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2732679B1 (fr) * 1995-04-07 1997-04-30 Synthelabo Procede de preparation enzymatique d'un intermediaire de synthese de la befloxatone
IL153594A0 (en) * 2000-07-13 2003-07-06 Sankyo Co Amino alcohol derivatives and pharmaceutical compositions containing the same
WO2005049056A2 (en) * 2003-11-14 2005-06-02 Ucl Biomedica Plc Immune modulator comprising whole cell rhodococcus, gordonia, nocardia, dietzia, tsukamurella or nocardioides bacteria
CN1948499B (zh) * 2006-05-26 2010-12-08 江南大学 生物催化制备(r)-4,4,4-三氟-3-羟基丁酸乙酯的方法
CN102719496B (zh) * 2012-06-21 2014-08-06 浙江工业大学 一种微生物转化苯甲酰甲酸乙酯制备(s)-(+)-扁桃酸乙酯的方法
CN103290072B (zh) * 2013-02-28 2014-10-22 南京工业大学 一种酶法不对称还原制备(s)-4-氯-3羟基丁酸乙酯的方法
CN104313064A (zh) * 2014-10-01 2015-01-28 青岛科技大学 一种细胞法生产手性溴苯基丙酸甲酯的方法
CN105838772A (zh) * 2016-05-27 2016-08-10 苏州汉酶生物技术有限公司 (s)-5-氯-2,3-二氢-2-羟基-1-氧代-1h-茚-2-羧酸甲酯的生物制备方法
CN105969815B (zh) * 2016-06-07 2021-02-26 苏州汉酶生物技术有限公司 一种(s)-5-氯-2,3-二氢-2-羟基-1-氧代-1h-茚-2-羧酸甲酯的生物制备方法
CN110527646B (zh) * 2019-08-20 2021-05-11 浙江工业大学 热带芽孢杆菌wzz018及其应用
CN112345663B (zh) * 2020-10-22 2022-10-21 京博农化科技有限公司 一种5-氯-2-甲氧羰基-1-茚酮酯含量的分析方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0197474B1 (en) * 1985-04-01 1991-07-10 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Process for preparing optically active indoline-2-carboxylic acid
US4668628A (en) * 1985-04-01 1987-05-26 Stauffer Chemical Company Resolution of racemic mixtures of aliphatic acid esters
IL91453A0 (en) * 1988-09-02 1990-04-29 Tanabe Seiyaku Co Preparation of optically active 3-phenyl-glycidic acid esters
US5202260A (en) * 1991-05-08 1993-04-13 Genzyme Corporation Resolution of α-tertiary carboxylic acid esters using lipase from Candida lipolytica
CA2068038A1 (en) * 1991-05-08 1992-11-09 Christopher Yee Enzymatic resolution of .alpha.-tertiary carboxylic acid esters

Also Published As

Publication number Publication date
JP3794702B2 (ja) 2006-07-12
IL115594A (en) 2000-01-31
WO1996012035A1 (en) 1996-04-25
IL115594A0 (en) 1996-01-19
ES2128093T3 (es) 1999-05-01
EP0786012A1 (en) 1997-07-30
DE69506900D1 (de) 1999-02-04
EP0786012B1 (en) 1998-12-23
CZ111197A3 (en) 1997-07-16
JPH10507360A (ja) 1998-07-21
AU3832995A (en) 1996-05-06
CN1160421A (zh) 1997-09-24
DE69506900T2 (de) 1999-07-22

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