EE05157B1 - N-[(asendatud bensüül)-4-piperidinüüli v?i pürrolidinüül]aminohüdroksüalkoksüfenüülide derivaadid, meetod nende valmistamiseks ning nende kasutamine meditsiinis - Google Patents
N-[(asendatud bensüül)-4-piperidinüüli v?i pürrolidinüül]aminohüdroksüalkoksüfenüülide derivaadid, meetod nende valmistamiseks ning nende kasutamine meditsiinisInfo
- Publication number
- EE05157B1 EE05157B1 EEP200200704A EEP200200704A EE05157B1 EE 05157 B1 EE05157 B1 EE 05157B1 EE P200200704 A EEP200200704 A EE P200200704A EE P200200704 A EEP200200704 A EE P200200704A EE 05157 B1 EE05157 B1 EE 05157B1
- Authority
- EE
- Estonia
- Prior art keywords
- hydroxyalkoxyphenyls
- pyrrolidinyl
- piperidinyl
- medicine
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0002331A SE0002331D0 (sv) | 2000-06-20 | 2000-06-20 | Novel compounds |
SE0004480A SE0004480D0 (sv) | 2000-12-05 | 2000-12-05 | Novel compounds |
PCT/SE2001/001377 WO2001098273A1 (fr) | 2000-06-20 | 2001-06-14 | Nouveaux composes |
Publications (2)
Publication Number | Publication Date |
---|---|
EE200200704A EE200200704A (et) | 2004-08-16 |
EE05157B1 true EE05157B1 (et) | 2009-04-15 |
Family
ID=26655154
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EEP200200704A EE05157B1 (et) | 2000-06-20 | 2001-06-14 | N-[(asendatud bensüül)-4-piperidinüüli v?i pürrolidinüül]aminohüdroksüalkoksüfenüülide derivaadid, meetod nende valmistamiseks ning nende kasutamine meditsiinis |
Country Status (22)
Country | Link |
---|---|
US (3) | US6911458B2 (fr) |
EP (1) | EP1299357A1 (fr) |
JP (1) | JP4022142B2 (fr) |
KR (1) | KR100799061B1 (fr) |
CN (1) | CN1307157C (fr) |
AR (1) | AR028948A1 (fr) |
AU (2) | AU2001274763B2 (fr) |
BR (1) | BR0111667A (fr) |
CA (1) | CA2414095C (fr) |
CZ (1) | CZ20024146A3 (fr) |
EE (1) | EE05157B1 (fr) |
HU (1) | HUP0301187A3 (fr) |
IL (2) | IL153167A0 (fr) |
IS (1) | IS6658A (fr) |
MX (1) | MXPA02012425A (fr) |
MY (1) | MY136520A (fr) |
NO (1) | NO324698B1 (fr) |
NZ (1) | NZ523047A (fr) |
PL (1) | PL203936B1 (fr) |
RU (2) | RU2419608C2 (fr) |
SK (1) | SK17932002A3 (fr) |
WO (1) | WO2001098273A1 (fr) |
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AR035230A1 (es) * | 2001-03-19 | 2004-05-05 | Astrazeneca Ab | Compuestos de bencimidazol, proceso para su preparacion, composicion farmaceutica, proceso para la preparacion de dicha composicion farmaceutica, y usos de estos compuestos para la elaboracion de medicamentos |
SE0202133D0 (sv) | 2002-07-08 | 2002-07-08 | Astrazeneca Ab | Novel compounds |
CA2515838A1 (fr) * | 2003-02-17 | 2004-08-26 | F. Hoffmann-La Roche Ag | Derives de piperidine-benzenesulfonamide |
US7851615B2 (en) | 2003-04-17 | 2010-12-14 | Alnylam Pharmaceuticals, Inc. | Lipophilic conjugated iRNA agents |
US7723509B2 (en) | 2003-04-17 | 2010-05-25 | Alnylam Pharmaceuticals | IRNA agents with biocleavable tethers |
JP4597976B2 (ja) | 2003-04-17 | 2010-12-15 | アルナイラム ファーマシューティカルズ インコーポレイテッド | 修飾iRNA剤 |
US8017762B2 (en) | 2003-04-17 | 2011-09-13 | Alnylam Pharmaceuticals, Inc. | Modified iRNA agents |
US8796436B2 (en) | 2003-04-17 | 2014-08-05 | Alnylam Pharmaceuticals, Inc. | Modified iRNA agents |
US7732442B2 (en) | 2003-09-05 | 2010-06-08 | Ono Pharmaceutical Co., Ltd. | Chemokine receptor antagonist and medical use thereof |
SE0303090D0 (sv) | 2003-11-20 | 2003-11-20 | Astrazeneca Ab | Novel compounds |
SE0303541D0 (sv) | 2003-12-22 | 2003-12-22 | Astrazeneca Ab | New compounds |
CA2617127A1 (fr) * | 2005-08-01 | 2007-02-08 | Astrazeneca Ab | Nouveaux derives de piperidine en tant que modulateurs de recepteur de chimiokine utiles pour le traitement des affections respiratoires |
TW200738635A (en) * | 2005-08-02 | 2007-10-16 | Astrazeneca Ab | New salt |
TW200738634A (en) * | 2005-08-02 | 2007-10-16 | Astrazeneca Ab | New salt |
TW200734305A (en) * | 2005-08-02 | 2007-09-16 | Astrazeneca Ab | New salt III |
TW200744612A (en) * | 2005-08-26 | 2007-12-16 | Astrazeneca Ab | New combination |
JO2769B1 (en) | 2005-10-26 | 2014-03-15 | جانسين فارماسوتيكا ان. في | Rapid decomposition of physiologically antagonistic agents of the 2-dopamine receptor |
TW200800895A (en) * | 2005-11-02 | 2008-01-01 | Astrazeneca Ab | Novel compounds |
CN101437797A (zh) * | 2006-03-07 | 2009-05-20 | 阿斯利康(瑞典)有限公司 | 哌啶衍生物,制备它们的方法,它们作为治疗剂的用途和含有它们的药物组合物 |
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US20080064884A1 (en) * | 2006-05-10 | 2008-03-13 | Astrazeneca Ab | Novel Process 1 |
US20100041905A1 (en) * | 2006-07-18 | 2010-02-18 | Astrazeneca Ab | Process for the Preparation of Substituted 2-Acetylamino-Alkoxyphenyl |
JO2642B1 (en) | 2006-12-08 | 2012-06-17 | جانسين فارماسوتيكا ان. في | Dopamine 2 receptor antagonists are rapidly hydrolyzed |
GB0702456D0 (en) | 2007-02-08 | 2007-03-21 | Astrazeneca Ab | New combination |
JO2849B1 (en) | 2007-02-13 | 2015-03-15 | جانسين فارماسوتيكا ان. في | Dopamine 2 receptor antagonists are rapidly hydrolyzed |
US20110136843A1 (en) * | 2007-02-23 | 2011-06-09 | Tomas Eriksson | Novel Combination of Compounds to be Used in the Treatment of Airway Diseases, Especially Chronic Obstructive Pulmonary Disease (COPD) and Asthma |
WO2008121065A1 (fr) * | 2007-03-30 | 2008-10-09 | Astrazeneca Ab | Nouveaux dérivés de pyrrolidine utilisés comme antagonistes du récepteur de chimiokines |
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CN102171189B (zh) | 2008-07-31 | 2013-11-20 | 詹森药业有限公司 | 作为快速解离多巴胺2受体拮抗剂的哌嗪-1-基-三氟甲基取代的吡啶 |
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WO2011061527A1 (fr) | 2009-11-17 | 2011-05-26 | Astrazeneca Ab | Combinaisons qui comprennent un modulateur du récepteur glucocorticoïde, destinées au traitement de maladies respiratoires |
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GB0029562D0 (en) | 2000-12-04 | 2001-01-17 | Novartis Ag | Organic compounds |
GB2373186A (en) | 2001-02-23 | 2002-09-18 | Astrazeneca Ab | Pharmaceutical combinations of a CCR3 antagonist and a compound which is usefulreatment of asthma, allergic disease or inflammation |
AR035230A1 (es) | 2001-03-19 | 2004-05-05 | Astrazeneca Ab | Compuestos de bencimidazol, proceso para su preparacion, composicion farmaceutica, proceso para la preparacion de dicha composicion farmaceutica, y usos de estos compuestos para la elaboracion de medicamentos |
ES2296923T3 (es) | 2001-03-22 | 2008-05-01 | Glaxo Group Limited | Derivados formanilidas como agonistas del adrenorreceptor beta2. |
GB0107228D0 (en) | 2001-03-22 | 2001-05-16 | Astrazeneca Ab | Chemical compounds |
SE0101038D0 (sv) | 2001-03-23 | 2001-03-23 | Astrazeneca Ab | Novel compounds |
KR100406536B1 (ko) * | 2001-03-28 | 2003-11-20 | 주식회사 하이닉스반도체 | 산소확산방지막으로서 알루미늄 산화막을 구비하는강유전체 메모리 소자 및 그 제조 방법 |
GB0108046D0 (en) | 2001-03-30 | 2001-05-23 | Astrazeneca Ab | Chemical compounds |
EP1389616B1 (fr) | 2001-04-27 | 2011-07-27 | Mitsubishi Tanabe Pharma Corporation | Dérivés de 3,4-dihalobenzylpipéridine et leur utilisation médicale |
HUP0400070A2 (hu) | 2001-04-30 | 2004-04-28 | Glaxo Group Limited | 17alfa-helyzetben ciklusos észtercsoportot tartalmazó androsztán-17béta-karbotiosav-észter-származékok mint gyulladásgátló szerek, eljárás a vegyületek előállítására és ezeket tartalmazó gyógyszerkészítmények |
US6730951B2 (en) * | 2001-06-25 | 2004-05-04 | Matsushita Electric Industrial Co., Ltd. | Capacitor, semiconductor memory device, and method for manufacturing the same |
JP4467229B2 (ja) * | 2001-09-12 | 2010-05-26 | 株式会社ハイニックスセミコンダクター | 半導体素子の製造方法 |
TWI249515B (en) | 2001-11-13 | 2006-02-21 | Theravance Inc | Aryl aniline beta2 adrenergic receptor agonists |
GB0127547D0 (en) | 2001-11-16 | 2002-01-09 | Astrazeneca Ab | Chemical compounds |
SE0104251D0 (sv) | 2001-12-14 | 2001-12-14 | Astrazeneca Ab | Novel compounds |
TW200303304A (en) | 2002-02-18 | 2003-09-01 | Astrazeneca Ab | Chemical compounds |
SE0200919D0 (sv) | 2002-03-25 | 2002-03-25 | Astrazeneca Ab | Chemical compounds |
GB0207436D0 (en) | 2002-03-28 | 2002-05-08 | Glaxo Group Ltd | Novel compounds |
US6583507B1 (en) * | 2002-04-26 | 2003-06-24 | Bum Ki Moon | Barrier for capacitor over plug structures |
CA2499314C (fr) | 2002-10-11 | 2010-08-24 | Pfizer Inc. | Derives d'indole utilises comme agonistes beta-2 |
KR100578212B1 (ko) * | 2003-06-30 | 2006-05-11 | 주식회사 하이닉스반도체 | 엠티피 구조의 강유전체 캐패시터 및 그 제조 방법 |
US7180141B2 (en) * | 2004-12-03 | 2007-02-20 | Texas Instruments Incorporated | Ferroelectric capacitor with parallel resistance for ferroelectric memory |
CA2617127A1 (fr) | 2005-08-01 | 2007-02-08 | Astrazeneca Ab | Nouveaux derives de piperidine en tant que modulateurs de recepteur de chimiokine utiles pour le traitement des affections respiratoires |
TW200738634A (en) | 2005-08-02 | 2007-10-16 | Astrazeneca Ab | New salt |
TW200734305A (en) | 2005-08-02 | 2007-09-16 | Astrazeneca Ab | New salt III |
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2001
- 2001-06-11 AR ARP010102758A patent/AR028948A1/es unknown
- 2001-06-14 JP JP2002504229A patent/JP4022142B2/ja not_active Expired - Lifetime
- 2001-06-14 KR KR1020027017281A patent/KR100799061B1/ko not_active IP Right Cessation
- 2001-06-14 RU RU2006141320/04A patent/RU2419608C2/ru not_active IP Right Cessation
- 2001-06-14 US US10/311,841 patent/US6911458B2/en not_active Expired - Fee Related
- 2001-06-14 RU RU2002132385/04A patent/RU2298550C2/ru not_active IP Right Cessation
- 2001-06-14 IL IL15316701A patent/IL153167A0/xx unknown
- 2001-06-14 EE EEP200200704A patent/EE05157B1/xx not_active IP Right Cessation
- 2001-06-14 CA CA002414095A patent/CA2414095C/fr not_active Expired - Fee Related
- 2001-06-14 CN CNB018142141A patent/CN1307157C/zh not_active Expired - Fee Related
- 2001-06-14 SK SK1793-2002A patent/SK17932002A3/sk not_active Application Discontinuation
- 2001-06-14 WO PCT/SE2001/001377 patent/WO2001098273A1/fr active IP Right Grant
- 2001-06-14 CZ CZ20024146A patent/CZ20024146A3/cs unknown
- 2001-06-14 HU HU0301187A patent/HUP0301187A3/hu unknown
- 2001-06-14 MX MXPA02012425A patent/MXPA02012425A/es active IP Right Grant
- 2001-06-14 AU AU2001274763A patent/AU2001274763B2/en not_active Ceased
- 2001-06-14 BR BR0111667-3A patent/BR0111667A/pt not_active Application Discontinuation
- 2001-06-14 PL PL366198A patent/PL203936B1/pl not_active IP Right Cessation
- 2001-06-14 NZ NZ523047A patent/NZ523047A/en unknown
- 2001-06-14 EP EP01941406A patent/EP1299357A1/fr not_active Withdrawn
- 2001-06-14 AU AU7476301A patent/AU7476301A/xx active Pending
- 2001-06-18 MY MYPI20012866A patent/MY136520A/en unknown
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- 2002-11-28 IL IL153167A patent/IL153167A/en not_active IP Right Cessation
- 2002-12-17 NO NO20026064A patent/NO324698B1/no not_active IP Right Cessation
- 2002-12-17 IS IS6658A patent/IS6658A/is unknown
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KB4A | Valid patent at the end of a year |
Effective date: 20101231 |
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MM4A | Lapsed by not paying the annual fees |
Effective date: 20100614 |