SE0200919D0 - Chemical compounds - Google Patents

Chemical compounds

Info

Publication number
SE0200919D0
SE0200919D0 SE0200919A SE0200919A SE0200919D0 SE 0200919 D0 SE0200919 D0 SE 0200919D0 SE 0200919 A SE0200919 A SE 0200919A SE 0200919 A SE0200919 A SE 0200919A SE 0200919 D0 SE0200919 D0 SE 0200919D0
Authority
SE
Sweden
Prior art keywords
sup
chemical compounds
activity
compounds
solvate
Prior art date
Application number
SE0200919A
Other languages
English (en)
Inventor
John Cumming
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Priority to SE0200919A priority Critical patent/SE0200919D0/sv
Publication of SE0200919D0 publication Critical patent/SE0200919D0/sv
Priority to TW092105784A priority patent/TW200305417A/zh
Priority to CNA038064642A priority patent/CN1642913A/zh
Priority to US10/508,895 priority patent/US20050171353A1/en
Priority to PCT/SE2003/000480 priority patent/WO2003080574A1/en
Priority to JP2003578329A priority patent/JP2005526797A/ja
Priority to AU2003216012A priority patent/AU2003216012A1/en
Priority to KR10-2004-7015310A priority patent/KR20040094876A/ko
Priority to MXPA04009162A priority patent/MXPA04009162A/es
Priority to BR0308592-9A priority patent/BR0308592A/pt
Priority to IL16389603A priority patent/IL163896A0/xx
Priority to CA002479887A priority patent/CA2479887A1/en
Priority to EP03745059A priority patent/EP1490336A1/en
Priority to ARP030101026A priority patent/AR039125A1/es
Priority to ZA200407414A priority patent/ZA200407414B/en
Priority to NO20044545A priority patent/NO20044545L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
SE0200919A 2002-03-25 2002-03-25 Chemical compounds SE0200919D0 (sv)

Priority Applications (16)

Application Number Priority Date Filing Date Title
SE0200919A SE0200919D0 (sv) 2002-03-25 2002-03-25 Chemical compounds
TW092105784A TW200305417A (en) 2002-03-25 2003-03-17 Chemical compounds
EP03745059A EP1490336A1 (en) 2002-03-25 2003-03-24 Piperidine or 8-aza-bicyclo(3.2.1)oct-3-yl derivatives useful as modulators of chemokine receptor activity (especially ccr5)
AU2003216012A AU2003216012A1 (en) 2002-03-25 2003-03-24 Piperidine or 8-aza-bicyclo[3.2.1]oct-3-yl derivatives useful as modulators of chemokine receptor activity (especially CCR5)
BR0308592-9A BR0308592A (pt) 2002-03-25 2003-03-24 Derivados de piperidina ou 8-azabiciclo [3.2.1] oct-3-il-piperidina, de utilidade como moduladores da atividade do receptor de quimocina (especialmente ccr5)
PCT/SE2003/000480 WO2003080574A1 (en) 2002-03-25 2003-03-24 Piperidine or 8-aza-bicyclo[3.2.1]oct-3-yl derivatives useful as modulators of chemokine receptor activity (especially ccr5)
JP2003578329A JP2005526797A (ja) 2002-03-25 2003-03-24 ケモカイン受容体活性（特にｃｃｒ５）のモジュレーターとして有用なピペリジンまたは８−アザ−ビシクロ［３．２．１］オクタ−３−イル誘導体
CNA038064642A CN1642913A (zh) 2002-03-25 2003-03-24 用作趋化因子受体活性(尤其是ccr5)调节剂的哌啶或8－氮杂－二环[3.2.1]辛－3－基衍生物
KR10-2004-7015310A KR20040094876A (ko) 2002-03-25 2003-03-24 케모킨 수용체 활성 (특히 ｃｃｒ5)의 조절제로서 유용한피페리딘 또는 8-아자-바이시클로[3.2.1]옥트-3-일 유도체
MXPA04009162A MXPA04009162A (es) 2002-03-25 2003-03-24 Derivados de piperidina u 8-aza-biciclo[3.2.1]oct-3-ilo empleados como moduladores de actividad del receptor de quimiocina (especialmente ccr5).
US10/508,895 US20050171353A1 (en) 2002-03-25 2003-03-24 Piperidine or 8-aza-bicyclo[3.2.1]oct-3-yl derivatives useful as modulators of chemokine receptor activity (especially ccr5)
IL16389603A IL163896A0 (en) 2002-03-25 2003-03-24 Piperidine or 8-aza-bicycloÄ3.2.1Üoct-3-yl derivatives useful as modulators of chemokine receptoractivity (especially ccr5)
CA002479887A CA2479887A1 (en) 2002-03-25 2003-03-24 Piperidine or 8-aza-bicyclo¬3.2.1|oct-3-yl derivatives useful as modulators of chemokine receptor activity (especially ccr5)
ARP030101026A AR039125A1 (es) 2002-03-25 2003-03-25 Derivados de piperidina o 8-aza-biciclo(3.2.1.)octa-3-il derivados, utiles como moduladores de receptores de actividad de quemoquinas
ZA200407414A ZA200407414B (en) 2002-03-25 2004-09-15 Piperidine or 8-aza-bicyclo[3.2.1]oct-3-yl derivatives useful as modulators of chemokine receptor activity (especially CCR5).
NO20044545A NO20044545L (no) 2002-03-25 2004-10-22 Piperidin-eller 8-aza-bicyklo[3.2.1.]okt-3-yl derivater som er nyttige som modulatorer for kemokireseptoraktivitet (spesielt CCR5)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0200919A SE0200919D0 (sv) 2002-03-25 2002-03-25 Chemical compounds

Publications (1)

Publication Number Publication Date
SE0200919D0 true SE0200919D0 (sv) 2002-03-25

Family

ID=20287391

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0200919A SE0200919D0 (sv) 2002-03-25 2002-03-25 Chemical compounds

Country Status (16)

Country Link
US (1) US20050171353A1 (sv)
EP (1) EP1490336A1 (sv)
JP (1) JP2005526797A (sv)
KR (1) KR20040094876A (sv)
CN (1) CN1642913A (sv)
AR (1) AR039125A1 (sv)
AU (1) AU2003216012A1 (sv)
BR (1) BR0308592A (sv)
CA (1) CA2479887A1 (sv)
IL (1) IL163896A0 (sv)
MX (1) MXPA04009162A (sv)
NO (1) NO20044545L (sv)
SE (1) SE0200919D0 (sv)
TW (1) TW200305417A (sv)
WO (1) WO2003080574A1 (sv)
ZA (1) ZA200407414B (sv)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR028948A1 (es) 2000-06-20 2003-05-28 Astrazeneca Ab Compuestos novedosos
SE0301369D0 (sv) * 2003-05-09 2003-05-09 Astrazeneca Ab Chemical compounds
SE0302090D0 (sv) * 2003-07-16 2003-07-16 Astrazeneca Ab Chemical compounds
US7498346B2 (en) * 2003-12-11 2009-03-03 Genzyme Corporation Chemokine receptor binding compounds
SE0303396D0 (sv) * 2003-12-16 2003-12-16 Astrazeneca Ab Chemical compounds
TW200538098A (en) * 2004-03-22 2005-12-01 Astrazeneca Ab Therapeutic agents
ES2277745B1 (es) * 2005-06-14 2008-06-01 Laboratorios Almirall S.A. Derivados n-amida de 8-azabiciclo /3.2.1/oct-3-ilo como antagonistas de ccr1.
JP2008543858A (ja) * 2005-06-15 2008-12-04 ジェンザイム・コーポレーション ケモカインレセプター結合化合物
CA2617127A1 (en) * 2005-08-01 2007-02-08 Astrazeneca Ab Novel piperidine derivatives as chemokine receptor modulators useful for the treatment of respiratory diseases.
CA2625047A1 (en) 2005-10-19 2007-04-26 F. Hoffmann-La Roche Ag Phenyl-acetamide nnrt inhibitors
DK2057125T3 (da) 2006-08-16 2011-05-16 Hoffmann La Roche Ikke-nucleosid revers transkriptase-inhibitorer
KR101475091B1 (ko) 2006-12-13 2014-12-22 에프. 호프만-라 로슈 아게 비뉴클레오시드 역전사 효소 억제제로서 2-(피페리딘-4-일)-4-페녹시- 또는 페닐아미노-피리미딘 유도체
WO2009010478A2 (en) * 2007-07-13 2009-01-22 Euroscreen S.A. Use of piperidine derivatives as agonists of chemokine receptor activity
CN101412692B (zh) * 2007-10-18 2012-10-17 中国科学院上海药物研究所 1-(3-氨基丙基)哌啶-4-氨基酰胺类化合物、其药物组合物及其制备方法和用途
CN101712679B (zh) * 2008-10-08 2013-04-10 中国科学院上海药物研究所 一种酰胺类化合物、其药物组合物及其制备方法和用途
CN102140104B (zh) * 2010-02-03 2014-11-12 中国科学院上海药物研究所 1-(3-(s)-氨基丙基)-哌啶-4-氨基酰胺类化合物、其药物组合物及其制备方法和用途
WO2012113103A1 (en) 2011-02-25 2012-08-30 Helsinn Healthcare S.A. Asymmetric ureas and medical uses thereof
CN106977511B (zh) * 2011-12-19 2019-04-12 中国科学院上海药物研究所 一种氨基丙基取代托烷胺类化合物、其药物组合物及其制备方法和用途
PL3390355T3 (pl) 2016-03-22 2023-05-02 Helsinn Healthcare S.A. Benzenosulfonylo-asymetryczne związki mocznikowe i ich zastosowania medyczne

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1013276A1 (en) * 1998-12-23 2000-06-28 Pfizer Inc. Aminoazacycloalkanes as CCR5 modulators
AU5473800A (en) * 1999-06-11 2001-01-02 Merck & Co., Inc. Cyclopentyl modulators of chemokine receptor activity
SE9902987D0 (sv) * 1999-08-24 1999-08-24 Astra Pharma Prod Novel compounds
GB0011838D0 (en) * 2000-05-17 2000-07-05 Astrazeneca Ab Chemical compounds
TR200400541T4 (tr) * 2000-05-26 2004-04-21 Pfizer Inc. Terapide faydalı tropan türevleri.
JP2004520423A (ja) * 2001-03-01 2004-07-08 アストラゼネカ・アクチエボラーグ Ｃｃｒ５モジュレーターとしてのｎ−ピペリジニル化合物
GB0107228D0 (en) * 2001-03-22 2001-05-16 Astrazeneca Ab Chemical compounds

Also Published As

Publication number Publication date
TW200305417A (en) 2003-11-01
AR039125A1 (es) 2005-02-09
CN1642913A (zh) 2005-07-20
MXPA04009162A (es) 2004-12-07
WO2003080574A1 (en) 2003-10-02
CA2479887A1 (en) 2003-10-02
JP2005526797A (ja) 2005-09-08
EP1490336A1 (en) 2004-12-29
US20050171353A1 (en) 2005-08-04
AU2003216012A1 (en) 2003-10-08
BR0308592A (pt) 2005-02-09
IL163896A0 (en) 2005-12-18
KR20040094876A (ko) 2004-11-10
NO20044545L (no) 2004-12-13
ZA200407414B (en) 2005-08-29

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