EE04720B1 - Pürrolidinüül-, piperidüül- või homopiperidüül-asendatud bensodioksaani, bensofuraani või bensopüraani derivaadid, nende valmistamismeetod, farmatseutiline kompositsioon ja selle valmistamismeetod - Google Patents
Pürrolidinüül-, piperidüül- või homopiperidüül-asendatud bensodioksaani, bensofuraani või bensopüraani derivaadid, nende valmistamismeetod, farmatseutiline kompositsioon ja selle valmistamismeetodInfo
- Publication number
- EE04720B1 EE04720B1 EEP200100640A EEP200100640A EE04720B1 EE 04720 B1 EE04720 B1 EE 04720B1 EE P200100640 A EEP200100640 A EE P200100640A EE P200100640 A EEP200100640 A EE P200100640A EE 04720 B1 EE04720 B1 EE 04720B1
- Authority
- EE
- Estonia
- Prior art keywords
- preparation
- homopiperidyl
- benzofuran
- piperidyl
- pyrrolidinyl
- Prior art date
Links
- IANQTJSKSUMEQM-UHFFFAOYSA-N 1-benzofuran Chemical class C1=CC=C2OC=CC2=C1 IANQTJSKSUMEQM-UHFFFAOYSA-N 0.000 title 2
- 238000000034 method Methods 0.000 title 2
- 150000001562 benzopyrans Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000005936 piperidyl group Chemical group 0.000 title 1
- LYKMMUBOEFYJQG-UHFFFAOYSA-N piperoxan Chemical class C1OC2=CC=CC=C2OC1CN1CCCCC1 LYKMMUBOEFYJQG-UHFFFAOYSA-N 0.000 title 1
- 125000000719 pyrrolidinyl group Chemical group 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nutrition Science (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99201746 | 1999-06-02 | ||
| PCT/EP2000/004747 WO2000075137A1 (en) | 1999-06-02 | 2000-05-23 | Pyrrolidinyl, piperidinyl or homopiperidinyl substituted (benzodioxan, benzofuran or benzopyran) derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EE200100640A EE200100640A (et) | 2003-02-17 |
| EE04720B1 true EE04720B1 (et) | 2006-10-16 |
Family
ID=8240259
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EEP200100640A EE04720B1 (et) | 1999-06-02 | 2000-05-23 | Pürrolidinüül-, piperidüül- või homopiperidüül-asendatud bensodioksaani, bensofuraani või bensopüraani derivaadid, nende valmistamismeetod, farmatseutiline kompositsioon ja selle valmistamismeetod |
Country Status (30)
| Country | Link |
|---|---|
| US (2) | US6900222B1 (de) |
| EP (1) | EP1187831B1 (de) |
| JP (1) | JP2003501428A (de) |
| KR (1) | KR100702526B1 (de) |
| CN (1) | CN1131862C (de) |
| AR (1) | AR033645A1 (de) |
| AT (1) | ATE279409T1 (de) |
| AU (1) | AU777601B2 (de) |
| BG (1) | BG65278B1 (de) |
| BR (1) | BR0011247A (de) |
| CA (1) | CA2374905C (de) |
| CZ (1) | CZ20014167A3 (de) |
| DE (1) | DE60014896T2 (de) |
| EA (1) | EA004648B1 (de) |
| EE (1) | EE04720B1 (de) |
| ES (1) | ES2231189T3 (de) |
| HR (1) | HRP20010869A2 (de) |
| HU (1) | HUP0201344A3 (de) |
| IL (1) | IL146824A0 (de) |
| MX (1) | MXPA01012323A (de) |
| MY (1) | MY120617A (de) |
| NO (1) | NO319950B1 (de) |
| NZ (1) | NZ515478A (de) |
| PL (1) | PL198532B1 (de) |
| SK (1) | SK286159B6 (de) |
| TR (1) | TR200103433T2 (de) |
| TW (1) | TW575571B (de) |
| UA (1) | UA73123C2 (de) |
| WO (1) | WO2000075137A1 (de) |
| ZA (1) | ZA200109863B (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1187829T3 (da) * | 1999-06-02 | 2004-04-13 | Janssen Pharmaceutica Nv | Aminoalkylsubstituerede (benzodioxan, benzofuran eller benzopyran) derivater |
| JO2352B1 (en) * | 2000-06-22 | 2006-12-12 | جانسين فارماسيوتيكا ان. في | Compounds for the treatment of non-adaptation of the bottom of the uterus |
| JO2654B1 (en) | 2000-09-04 | 2012-06-17 | شركة جانسين فارماسوتيكا ان. في | Multiple aryl caroxa amides are useful as lipid - lowering agents |
| JO2409B1 (en) | 2000-11-21 | 2007-06-17 | شركة جانسين فارماسوتيكا ان. في | Second-phenyl carboxy amides are useful as lipid-lowering agents |
| US7208495B2 (en) * | 2001-07-05 | 2007-04-24 | Takeda Pharmaceutical Company Limited | Benzo-fused 5-membered hetrocycle compounds, process for preparation of the same, and use thereof |
| CN101880277A (zh) | 2003-04-24 | 2010-11-10 | 因塞特公司 | 作为金属蛋白酶抑制剂的氮杂螺烷衍生物 |
| CN1696115B (zh) * | 2004-05-11 | 2010-06-09 | 中国科学院上海药物研究所 | 合成砌块4-取代基-4-氨基-哌啶衍生物、其制备方法和用途 |
| GB201612938D0 (en) * | 2016-07-26 | 2016-09-07 | Almac Discovery Ltd | Pharmaceutical compounds |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US19051A (en) * | 1858-01-05 | sloan | ||
| US3910930A (en) | 1973-01-04 | 1975-10-07 | Janssen Pharmaceutica Nv | 1-{55 1-{8 2-(1,4-Benzodioxan-2-yl)-2-hydroxyethyl{9 -4-piperidyl{56 -2-benzimidazolinones |
| US3929801A (en) | 1973-11-20 | 1975-12-30 | Janssen Pharmaceutica Nv | 2-Benzimidazolinones |
| GR71865B (de) | 1978-03-20 | 1983-07-07 | Ciba Geigy | |
| ES469096A1 (es) | 1978-04-24 | 1978-11-16 | Antibioticos Sa | Un procedimiento para la preparacion dos sustancialmente insolubles en agua. |
| DE2852945A1 (de) | 1978-12-07 | 1980-06-26 | Boehringer Sohn Ingelheim | Benzodioxanyl-hydroxyaethylpiperidyl- imidazolidinone, verfahren zu ihrer herstellung und diese enthaltende arzneimittel |
| US4329348A (en) * | 1979-02-26 | 1982-05-11 | Ciba-Geigy Corporation | N-Oxacyclic-alkylpiperidines as psychostimulants |
| DE3124366A1 (de) | 1981-06-20 | 1982-12-30 | Hoechst Ag, 6000 Frankfurt | N-oxacyclyl-alkylpiperidin-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische praeparate und deren verwendung |
| FR2533584B1 (fr) | 1982-09-28 | 1986-03-21 | Pasteur Institut | Procede de detection du pouvoir mutagene de substances, susceptibles d'induire la deterioration d'adn cellulaires, mettant en jeu la production d'une reponse sos |
| DE3901814A1 (de) | 1988-07-28 | 1990-02-01 | Bayer Ag | Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga |
| DE4140540A1 (de) | 1991-12-09 | 1993-06-17 | Bayer Ag | Neue azaheterocyclylmethyl-chromane |
| SI9300097B (en) | 1992-02-27 | 2001-12-31 | Janssen Pharmaceutica Nv | (benzodioxan, benzofuran or benzopyran) alkylamino) alkyl substituted guanidines |
| DE4319038A1 (de) * | 1993-06-08 | 1994-12-15 | Bayer Ag | Verwendung von teilweise bekannten substituierten Chromanen als Arzneimittel, neue Wirkstoffe und Verfahren zu ihrer Herstellung |
| RU2129556C1 (ru) | 1993-08-19 | 1999-04-27 | Жансен Фармасетика Н.В. | Производное дигидробензопирана, обладающее сосудосуживающим действием, промежуточные соединения, способы получения, фармацевтическая композиция и способ ее получения |
| US5541199A (en) | 1995-06-02 | 1996-07-30 | American Home Products Corporation | Chroman-2-ylmethylamino derivatives |
| FR2744451B1 (fr) | 1996-02-01 | 1998-04-24 | Pf Medicament | Nouvelles imidazolidinones, pyrimidinones, et 1,3-diazepin-2 -ones, leur preparation et leurs applications en therapeutique |
| US6133277A (en) | 1997-12-05 | 2000-10-17 | Janssen Pharmaceutica N.V. | (Benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties |
| DK1187829T3 (da) | 1999-06-02 | 2004-04-13 | Janssen Pharmaceutica Nv | Aminoalkylsubstituerede (benzodioxan, benzofuran eller benzopyran) derivater |
| JO2352B1 (en) | 2000-06-22 | 2006-12-12 | جانسين فارماسيوتيكا ان. في | Compounds for the treatment of non-adaptation of the bottom of the uterus |
-
2000
- 2000-05-23 UA UA2001128826A patent/UA73123C2/uk unknown
- 2000-05-23 CN CN008083177A patent/CN1131862C/zh not_active Expired - Fee Related
- 2000-05-23 AU AU45685/00A patent/AU777601B2/en not_active Ceased
- 2000-05-23 NZ NZ515478A patent/NZ515478A/xx unknown
- 2000-05-23 ES ES00927243T patent/ES2231189T3/es not_active Expired - Lifetime
- 2000-05-23 CZ CZ20014167A patent/CZ20014167A3/cs unknown
- 2000-05-23 DE DE60014896T patent/DE60014896T2/de not_active Expired - Lifetime
- 2000-05-23 BR BR0011247-0A patent/BR0011247A/pt not_active Application Discontinuation
- 2000-05-23 PL PL352063A patent/PL198532B1/pl not_active IP Right Cessation
- 2000-05-23 IL IL14682400A patent/IL146824A0/xx not_active IP Right Cessation
- 2000-05-23 EA EA200101237A patent/EA004648B1/ru not_active IP Right Cessation
- 2000-05-23 JP JP2001502420A patent/JP2003501428A/ja not_active Withdrawn
- 2000-05-23 WO PCT/EP2000/004747 patent/WO2000075137A1/en not_active Ceased
- 2000-05-23 HR HR20010869A patent/HRP20010869A2/hr not_active Application Discontinuation
- 2000-05-23 EE EEP200100640A patent/EE04720B1/xx not_active IP Right Cessation
- 2000-05-23 TR TR2001/03433T patent/TR200103433T2/xx unknown
- 2000-05-23 CA CA2374905A patent/CA2374905C/en not_active Expired - Lifetime
- 2000-05-23 US US09/980,451 patent/US6900222B1/en not_active Expired - Lifetime
- 2000-05-23 KR KR1020017014585A patent/KR100702526B1/ko not_active Expired - Fee Related
- 2000-05-23 HU HU0201344A patent/HUP0201344A3/hu unknown
- 2000-05-23 EP EP00927243A patent/EP1187831B1/de not_active Expired - Lifetime
- 2000-05-23 MX MXPA01012323A patent/MXPA01012323A/es active IP Right Grant
- 2000-05-23 SK SK1692-2001A patent/SK286159B6/sk not_active IP Right Cessation
- 2000-05-23 AT AT00927243T patent/ATE279409T1/de not_active IP Right Cessation
- 2000-05-24 TW TW89109976A patent/TW575571B/zh not_active IP Right Cessation
- 2000-05-30 MY MYPI20002410A patent/MY120617A/en unknown
- 2000-06-01 AR ARP000102715A patent/AR033645A1/es active IP Right Grant
-
2001
- 2001-11-28 BG BG106157A patent/BG65278B1/bg unknown
- 2001-11-29 ZA ZA200109863A patent/ZA200109863B/xx unknown
- 2001-11-30 NO NO20015865A patent/NO319950B1/no not_active IP Right Cessation
-
2005
- 2005-03-14 US US11/079,606 patent/US7358239B2/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB4A | Valid patent at the end of a year |
Effective date: 20061231 |
|
| KB4A | Valid patent at the end of a year |
Effective date: 20071231 |
|
| KB4A | Valid patent at the end of a year |
Effective date: 20081231 |
|
| MM4A | Lapsed by not paying the annual fees |
Effective date: 20100523 |