EE04240B1 - (S)-omeprasooli kaaliumisool - Google Patents

(S)-omeprasooli kaaliumisool

Info

Publication number
EE04240B1
EE04240B1 EEP200100395A EEP200100395A EE04240B1 EE 04240 B1 EE04240 B1 EE 04240B1 EE P200100395 A EEP200100395 A EE P200100395A EE P200100395 A EEP200100395 A EE P200100395A EE 04240 B1 EE04240 B1 EE 04240B1
Authority
EE
Estonia
Prior art keywords
omeprazole
potassium salt
potassium
salt
Prior art date
Application number
EEP200100395A
Other languages
English (en)
Estonian (et)
Inventor
Nilsson Maths
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of EE200100395A publication Critical patent/EE200100395A/xx
Publication of EE04240B1 publication Critical patent/EE04240B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
EEP200100395A 1999-01-28 2000-01-18 (S)-omeprasooli kaaliumisool EE04240B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9900274A SE9900274D0 (sv) 1999-01-28 1999-01-28 New compound
PCT/SE2000/000087 WO2000044744A1 (en) 1999-01-28 2000-01-18 Potassium salt of ($i(s))-omeprazole

Publications (2)

Publication Number Publication Date
EE200100395A EE200100395A (et) 2002-10-15
EE04240B1 true EE04240B1 (et) 2004-02-16

Family

ID=20414267

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200100395A EE04240B1 (et) 1999-01-28 2000-01-18 (S)-omeprasooli kaaliumisool

Country Status (40)

Country Link
US (1) US6511996B1 (sk)
EP (1) EP1149090B1 (sk)
JP (1) JP2002535401A (sk)
KR (1) KR100624054B1 (sk)
CN (1) CN1231477C (sk)
AR (1) AR022425A1 (sk)
AT (1) ATE236899T1 (sk)
AU (1) AU768676B2 (sk)
BG (1) BG65060B1 (sk)
BR (1) BR0007647A (sk)
CA (1) CA2357744C (sk)
CZ (1) CZ300504B6 (sk)
DE (1) DE60002042T2 (sk)
DK (1) DK1149090T3 (sk)
DZ (1) DZ3001A1 (sk)
EE (1) EE04240B1 (sk)
EG (1) EG23980A (sk)
ES (1) ES2193937T3 (sk)
HK (1) HK1041259B (sk)
HU (1) HU226766B1 (sk)
ID (1) ID30095A (sk)
IL (1) IL144107A0 (sk)
IS (1) IS2019B (sk)
MY (1) MY119095A (sk)
NO (1) NO319719B1 (sk)
NZ (1) NZ512804A (sk)
PL (1) PL197881B1 (sk)
PT (1) PT1149090E (sk)
RS (1) RS50200B (sk)
RU (1) RU2237666C2 (sk)
SA (1) SA00200895B1 (sk)
SE (1) SE9900274D0 (sk)
SI (1) SI1149090T1 (sk)
SK (1) SK285626B6 (sk)
TN (1) TNSN00017A1 (sk)
TR (1) TR200102138T2 (sk)
TW (1) TWI269795B (sk)
UA (1) UA71594C2 (sk)
WO (1) WO2000044744A1 (sk)
ZA (1) ZA200105526B (sk)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6875872B1 (en) * 1993-05-28 2005-04-05 Astrazeneca Compounds
SE9301830D0 (sv) * 1993-05-28 1993-05-28 Ab Astra New compounds
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
CN1842525A (zh) 2003-05-05 2006-10-04 兰贝克赛实验室有限公司 苯并咪唑衍生物的钡盐
US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
MXPA06011820A (es) * 2004-04-16 2006-12-15 Santarus Inc Combinacion de inhibidor de bomba de proton, agente regulador del ph y agente procinetico.
US8906940B2 (en) 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
NZ551970A (en) * 2004-06-24 2010-01-29 Astrazeneca Ab New process for the preparation of crystal modifications for use in the preparation of esomeprazole sodium salt
WO2006073779A1 (en) * 2004-12-30 2006-07-13 Transform Phamaceuticals, Inc. Novel omeprazole forms and related methods
ES2259269B1 (es) 2005-03-03 2007-11-01 Esteve Quimica, S.A. Procedimiento para la preparacion de derivados de 2-(2-piridilmetilsulfinil)-bencimidazol opticamente activos.
US7576219B2 (en) 2005-10-26 2009-08-18 Hanmi Pharm. Co., Ltd Crystalline S-omeprazole strontium hydrate, method for preparing same, and pharmaceutical composition containing same
EP1801110A1 (en) 2005-12-22 2007-06-27 KRKA, tovarna zdravil, d.d., Novo mesto Esomeprazole arginine salt
CN100384839C (zh) * 2006-02-17 2008-04-30 中国科学院上海有机化学研究所 [(取代的吡啶基)甲基]亚磺酰基-1h-苯并咪唑类化合物及其对映体的锌盐的制备方法
EP2040710A2 (en) * 2006-06-21 2009-04-01 Glenmark Pharmaceuticals Limited Novel polymorph of esomeprazole potassium and process for its preparation
EP2068841B1 (en) 2006-10-05 2018-09-26 Santarus, Inc. Novel formulations of proton pump inhibitors and methods of using these formulations
US20080103169A1 (en) 2006-10-27 2008-05-01 The Curators Of The University Of Missouri Compositions comprising acid labile proton pump inhibiting agents, at least one other pharmaceutically active agent and methods of using same
UY30755A1 (es) 2006-12-04 2008-07-31 Bayer Schering Pharma Ag Sal de potasio cristalina de analogos de lipoxina a4
FR2920428B1 (fr) * 2007-08-29 2012-06-15 Univ Rouen Procede de dedoublement de sels de l'omeprazole
WO2009074997A2 (en) * 2007-12-10 2009-06-18 Lee Pharma Ltd. A novel process for the preparation of crystalline magnesium salt of (s)-omeprazole di hydrate
EP2143722A1 (en) 2008-07-09 2010-01-13 Lek Pharmaceuticals D.D. Process for preparation of esomeprazole sodium of high chemical purity and new forms of esomeprazole sodium
WO2010097583A1 (en) 2009-02-24 2010-09-02 Cipla Limited Esomeprazole potassium polymorph and its preparation
WO2010122583A2 (en) 2009-04-24 2010-10-28 Rubicon Research Private Limited Oral pharmaceutical compositions of acid labile substances
WO2011071982A2 (en) 2009-12-08 2011-06-16 Codexis, Inc. Synthesis of prazole compounds
CN102319223B (zh) * 2011-09-21 2013-06-19 石药集团欧意药业有限公司 一种埃索美拉唑冻干制剂及其制备方法
CN102633776B (zh) * 2012-03-28 2014-06-18 中山市仁合药业有限公司 一种埃索美拉唑及其钠盐的制备方法
WO2024075017A1 (en) 2022-10-04 2024-04-11 Zabirnyk Arsenii Inhibition of aortic valve calcification

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7804231L (sv) 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
SE8301182D0 (sv) 1983-03-04 1983-03-04 Haessle Ab Novel compounds
GB2189698A (en) 1986-04-30 1987-11-04 Haessle Ab Coated omeprazole tablets
DE4035455A1 (de) 1990-11-08 1992-05-14 Byk Gulden Lomberg Chem Fab Enantiomerentrennung
US5877192A (en) 1993-05-28 1999-03-02 Astra Aktiebolag Method for the treatment of gastric acid-related diseases and production of medication using (-) enantiomer of omeprazole
SE9301830D0 (sv) * 1993-05-28 1993-05-28 Ab Astra New compounds
CA2170647C (en) 1994-07-08 2001-03-13 Pontus John Arvid Bergstrand Multiple unit tableted dosage form i
SE504459C2 (sv) 1994-07-15 1997-02-17 Astra Ab Förfarande för framställning av substituerade sulfoxider
GB9423968D0 (en) 1994-11-28 1995-01-11 Astra Ab Resolution
GB9423970D0 (en) 1994-11-28 1995-01-11 Astra Ab Oxidation
HRP960232A2 (en) 1995-07-03 1998-02-28 Astra Ab A process for the optical purification of compounds
SE510666C2 (sv) * 1996-12-20 1999-06-14 Astra Ab Nya Kristallmodifikationer
SE510650C2 (sv) * 1997-05-30 1999-06-14 Astra Ab Ny förening
SE510643C2 (sv) * 1997-06-27 1999-06-14 Astra Ab Termodynamiskt stabil omeprazol natrium form B

Also Published As

Publication number Publication date
NZ512804A (en) 2003-07-25
KR20010101699A (ko) 2001-11-14
EP1149090A1 (en) 2001-10-31
UA71594C2 (uk) 2004-12-15
RU2237666C2 (ru) 2004-10-10
CZ300504B6 (cs) 2009-06-03
SK10372001A3 (sk) 2002-02-05
HUP0105313A2 (hu) 2002-05-29
BG65060B1 (bg) 2007-01-31
PT1149090E (pt) 2003-07-31
HUP0105313A3 (en) 2003-01-28
PL197881B1 (pl) 2008-05-30
NO20013665D0 (no) 2001-07-26
WO2000044744A1 (en) 2000-08-03
IL144107A0 (en) 2002-05-23
BG105841A (en) 2002-04-30
ATE236899T1 (de) 2003-04-15
EG23980A (en) 2008-02-27
SA00200895B1 (ar) 2006-11-11
IS5989A (is) 2001-07-05
CA2357744C (en) 2009-06-16
CZ20012730A3 (cs) 2002-02-13
DE60002042D1 (de) 2003-05-15
AR022425A1 (es) 2002-09-04
JP2002535401A (ja) 2002-10-22
ZA200105526B (en) 2002-10-04
DZ3001A1 (fr) 2004-03-27
HU226766B1 (en) 2009-09-28
AU768676B2 (en) 2003-12-18
ID30095A (id) 2001-11-01
KR100624054B1 (ko) 2006-09-18
EE200100395A (et) 2002-10-15
SE9900274D0 (sv) 1999-01-28
IS2019B (is) 2005-06-15
YU53801A (sh) 2004-07-15
NO319719B1 (no) 2005-09-05
ES2193937T3 (es) 2003-11-16
DK1149090T3 (da) 2003-06-30
TWI269795B (en) 2007-01-01
DE60002042T2 (de) 2003-12-18
HK1041259A1 (en) 2002-07-05
NO20013665L (no) 2001-07-26
EP1149090B1 (en) 2003-04-09
BR0007647A (pt) 2001-10-16
AU2469400A (en) 2000-08-18
TR200102138T2 (tr) 2001-12-21
MY119095A (en) 2005-03-31
CA2357744A1 (en) 2000-08-03
CN1231477C (zh) 2005-12-14
HK1041259B (zh) 2003-10-24
SK285626B6 (sk) 2007-05-03
US6511996B1 (en) 2003-01-28
RS50200B (sr) 2009-07-15
CN1339034A (zh) 2002-03-06
TNSN00017A1 (fr) 2005-11-10
SI1149090T1 (en) 2003-10-31

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Legal Events

Date Code Title Description
KB4A Valid patent at the end of a year

Effective date: 20041231

KB4A Valid patent at the end of a year

Effective date: 20051231

KB4A Valid patent at the end of a year

Effective date: 20061231

KB4A Valid patent at the end of a year

Effective date: 20071231

KB4A Valid patent at the end of a year

Effective date: 20081231

KB4A Valid patent at the end of a year

Effective date: 20101231

MM4A Lapsed by not paying the annual fees

Effective date: 20120118