ECSP024342A - Nuevos derivados d e fenilpropargileter - Google Patents

Nuevos derivados d e fenilpropargileter

Info

Publication number
ECSP024342A
ECSP024342A EC2002004342A ECSP024342A ECSP024342A EC SP024342 A ECSP024342 A EC SP024342A EC 2002004342 A EC2002004342 A EC 2002004342A EC SP024342 A ECSP024342 A EC SP024342A EC SP024342 A ECSP024342 A EC SP024342A
Authority
EC
Ecuador
Prior art keywords
optionally substituted
alkyl
hydrogen
alkynyl
alkenyl
Prior art date
Application number
EC2002004342A
Other languages
English (en)
Inventor
Jurgen Dederichs
Thomas Rigassi
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9924043&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP024342(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of ECSP024342A publication Critical patent/ECSP024342A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Furan Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

La invención se refiere a derivados de fenilpropargiléter de la fórmula genera 1 que incluye los isómeros ópticos de los mismos y las mezclas de tales isómeros, EN DONDE r1 ES Hidrógeno, alquilo, cicloalquilo a arilo opcionalmente sustituido, R2 y R3 son independientemente entre sí hidrógeno o alquilo, R4 es alquilo, alquenilo o alquinilo, R5, R6, R7 y R8 son independientemente entre sí, hidrógeno o alquilo, R9 es hidrógeno, alquilo opcionalmente sustituido, alquenilo opcionalmente sustituido o alquinilo opcionalmente sustituido, R10 o es arilo opcionalmente sustituido o heteroarilo opcionalmente sustituido, y Z es halógeno, ariloxilo opcionalmente sustituido, alcoxilo opcionalmente sustituido, alqueniloxilo opcionalmente sustituido, alquiniloxilo opcionalmente sustituido, ariltio opcionalmente sustituido, alquiltio opcionalmente sustituido, alqueniltio opcionlmente sustituido, alquiniltio opcionalmente sustuido, alquilsulfinilo opcionalmente sustituido, alquenilsulfinilo opcionalmente sustituido, alquinilsufinilo opcionalmente sustituido, alquilsulfonilo opcionalmente sustituido, alquenilsufonilo opcionalmente sustituido o alquinilsulfonilo opcionanalmente sustituido. Estos compuestos poseen propiedades protectoras útiles para plantas y pueden ser convenientemente empleados en la práctica de la agricultura, para el control y la prevención de la infección de plantas por microorganismos fitopatogenicos, especialmente hongos.
EC2002004342A 2001-10-17 2002-11-19 Nuevos derivados d e fenilpropargileter ECSP024342A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0124953.1A GB0124953D0 (en) 2001-10-17 2001-10-17 Organic Compounds

Publications (1)

Publication Number Publication Date
ECSP024342A true ECSP024342A (es) 2003-03-10

Family

ID=9924043

Family Applications (2)

Application Number Title Priority Date Filing Date
EC2002004342A ECSP024342A (es) 2001-10-17 2002-11-19 Nuevos derivados d e fenilpropargileter
EC2002004341A ECSP024341A (es) 2001-10-17 2002-11-19 Composiciones farmaceuticas

Family Applications After (1)

Application Number Title Priority Date Filing Date
EC2002004341A ECSP024341A (es) 2001-10-17 2002-11-19 Composiciones farmaceuticas

Country Status (31)

Country Link
US (3) US20050013859A1 (es)
EP (1) EP1438040B2 (es)
JP (2) JP2005508959A (es)
KR (1) KR100671367B1 (es)
CN (1) CN1310640C (es)
AR (2) AR036813A1 (es)
AT (1) ATE374023T1 (es)
AU (1) AU2002338897B2 (es)
BR (1) BR0213355A (es)
CA (1) CA2460574A1 (es)
CO (1) CO5390076A1 (es)
CY (1) CY1107841T1 (es)
DE (1) DE60222687T3 (es)
DK (1) DK1438040T4 (es)
EC (2) ECSP024342A (es)
ES (1) ES2292819T5 (es)
GB (1) GB0124953D0 (es)
HU (1) HU231114B1 (es)
IL (2) IL160968A0 (es)
MX (1) MXPA04003636A (es)
MY (1) MY139206A (es)
NO (1) NO341804B1 (es)
NZ (1) NZ532280A (es)
PE (1) PE20030476A1 (es)
PL (2) PL415001A1 (es)
PT (1) PT1438040E (es)
RU (2) RU2338528C2 (es)
SI (1) SI1438040T2 (es)
TW (1) TWI333861B (es)
WO (1) WO2003032978A1 (es)
ZA (1) ZA200401977B (es)

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GB0419355D0 (en) * 2004-08-31 2004-09-29 Novartis Ag Organic compounds
WO2006086498A2 (en) * 2005-02-08 2006-08-17 Aspreva Pharmaceuticals Sa Treatment of vascular, autoimmune and inflammatory diseases using low dosages of impdh inhibitors
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JP5394746B2 (ja) 2005-12-21 2014-01-22 ビーエーエスエフ ソシエタス・ヨーロピア 錠剤崩壊剤としての微粒子状架橋ポリビニルピロリドン
CA2640283A1 (en) * 2006-02-13 2007-08-23 Novartis Ag High dosage of mycophenolic acid (mpa)
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BRPI0812064B8 (pt) 2007-06-06 2021-05-25 Basf Se formulação farmacêutica na forma de aglomerados, comprimidos, e, processo para a produção de uma formulação farmacêutica
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CN106727403A (zh) * 2017-01-03 2017-05-31 无锡福祈制药有限公司 一种麦考酚钠肠溶片及其制备方法
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WO2019236844A1 (en) 2018-06-06 2019-12-12 Metavant Sciences Gmbh Methods of treating subjects having diabetes with chronic kidney disease
MX2020013567A (es) 2018-06-14 2021-05-27 Poxel Tableta recubierta con pelicula que comprende un derivado de triazina para su uso en el tratamiento de la diabetes.
RU2723255C2 (ru) * 2018-11-14 2020-06-09 Общество с ограниченной ответственностью "Изварино Фарма" Экструдат с микофенолятом натрия для получения пероральной твердой лекарственной формы
WO2022162088A2 (en) * 2021-01-28 2022-08-04 Priothera Sas Methods of treatment with s1p receptor modulators
US20240261218A1 (en) * 2021-05-26 2024-08-08 The Texas A&M University System Biodegradable mucoadhesive pharmaceutical formulations and methods thereof
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Also Published As

Publication number Publication date
CN1310640C (zh) 2007-04-18
KR100671367B1 (ko) 2007-01-19
KR20050037409A (ko) 2005-04-21
PE20030476A1 (es) 2003-07-30
EP1438040B1 (en) 2007-09-26
EP1438040A1 (en) 2004-07-21
SI1438040T2 (sl) 2020-02-28
CA2460574A1 (en) 2003-04-24
PL367738A1 (en) 2005-03-07
NO341804B1 (no) 2018-01-22
ES2292819T5 (es) 2020-05-29
RU2381026C2 (ru) 2010-02-10
DE60222687D1 (de) 2007-11-08
RU2338528C2 (ru) 2008-11-20
PL415001A1 (pl) 2016-02-29
AR036813A1 (es) 2004-10-06
CO5390076A1 (es) 2004-04-30
DK1438040T4 (da) 2020-01-27
HK1067861A1 (en) 2005-04-22
DE60222687T2 (de) 2008-07-17
JP2005508959A (ja) 2005-04-07
PL234541B1 (pl) 2020-03-31
TWI333861B (en) 2010-12-01
ES2292819T3 (es) 2008-03-16
IL160968A0 (en) 2004-08-31
AU2002338897B2 (en) 2006-10-19
DK1438040T3 (da) 2008-02-04
PT1438040E (pt) 2008-01-02
US20100210717A1 (en) 2010-08-19
ATE374023T1 (de) 2007-10-15
US20050013859A1 (en) 2005-01-20
EP1438040B2 (en) 2019-10-16
RU2004115332A (ru) 2005-04-20
ZA200401977B (en) 2006-05-31
MY139206A (en) 2009-08-28
AR085778A2 (es) 2013-10-30
JP2009137996A (ja) 2009-06-25
NO20041785L (no) 2004-05-03
HUP0600451A2 (en) 2006-09-28
US20120237601A1 (en) 2012-09-20
GB0124953D0 (en) 2001-12-05
ECSP024341A (es) 2003-12-01
HU231114B1 (hu) 2020-09-28
MXPA04003636A (es) 2004-07-27
RU2007130786A (ru) 2009-02-20
NZ532280A (en) 2007-05-31
DE60222687T3 (de) 2020-03-05
CY1107841T1 (el) 2013-06-19
WO2003032978A1 (en) 2003-04-24
CN1564684A (zh) 2005-01-12
SI1438040T1 (sl) 2008-04-30
BR0213355A (pt) 2006-05-23
IL160968A (en) 2016-04-21

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