PE20030476A1 - Composiciones farmaceuticas de acido micofenolico - Google Patents
Composiciones farmaceuticas de acido micofenolicoInfo
- Publication number
- PE20030476A1 PE20030476A1 PE2002001013A PE2002001013A PE20030476A1 PE 20030476 A1 PE20030476 A1 PE 20030476A1 PE 2002001013 A PE2002001013 A PE 2002001013A PE 2002001013 A PE2002001013 A PE 2002001013A PE 20030476 A1 PE20030476 A1 PE 20030476A1
- Authority
- PE
- Peru
- Prior art keywords
- mycophenolic acid
- refers
- tablet
- preparation
- treatment
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Transplantation (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Furan Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
SE REFIERE A UNA FORMA DE DOSIS SOLIDA ORAL DE ACIDO MICOFENOLICO (EN FORMA DE SAL DE MICOFENOLATO DE SODIO CRISTALINA O ANHIDRA) PRESENTE DESDE 20% HASTA ALREDEDOR DEL 95% EN PESO, CON BASE EN EL PESO TOTAL DE LA FORMA DE DOSIS SOLIDA COMO UNA TABLETA, QUE COMPRENDE ADICIONALMENTE ADITIVOS PARA LA PREPARACION DE TABLETAS POR METODOS DE COMPRENSION, QUE SE RECUBRE ADEMAS DE FORMA ENTERICA; LAS TABLETAS PRESENTAN UNA FORMA ESTABLE MECANICA Y FAVORABLEMENTE CON UNA ELEVADA CARGA DE FARMACO. TAMBIEN SE REFIERE A UN PROCESO PARA LA PREPARACION QUE COMPRENDE: MEZCLA ACIDO O SAL DEL ACIDO MICOFENOLICO Y ADITIVOS; SOMETE A GRANULACION; COMPRIME LOS GRANULADOS PARA OBTENER LA TABLETA. TAMBIEN SE REFIERE AL USO CON OTRO INMUNOSUPRESOR. EL ACIDO MICOFENOLICO PUEDE SER UTIL PARA EL TRATAMIENTO DE RECHAZO A UN ORGANO TRANSGENICO O NATURAL, DE TRASPLANTE DE ALOINJERTO CELULAR O DE TEJIDO PARA EL TRATAMIENTO DE UNA ENFERMEDAD INMUNE INFLAMATORIA
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0124953.1A GB0124953D0 (en) | 2001-10-17 | 2001-10-17 | Organic Compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20030476A1 true PE20030476A1 (es) | 2003-07-30 |
Family
ID=9924043
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2002001013A PE20030476A1 (es) | 2001-10-17 | 2002-10-15 | Composiciones farmaceuticas de acido micofenolico |
Country Status (32)
Country | Link |
---|---|
US (3) | US20050013859A1 (es) |
EP (1) | EP1438040B2 (es) |
JP (2) | JP2005508959A (es) |
KR (1) | KR100671367B1 (es) |
CN (1) | CN1310640C (es) |
AR (2) | AR036813A1 (es) |
AT (1) | ATE374023T1 (es) |
AU (1) | AU2002338897B2 (es) |
BR (1) | BR0213355A (es) |
CA (1) | CA2460574A1 (es) |
CO (1) | CO5390076A1 (es) |
CY (1) | CY1107841T1 (es) |
DE (1) | DE60222687T3 (es) |
DK (1) | DK1438040T4 (es) |
EC (2) | ECSP024342A (es) |
ES (1) | ES2292819T5 (es) |
GB (1) | GB0124953D0 (es) |
HK (1) | HK1067861A1 (es) |
HU (1) | HU231114B1 (es) |
IL (2) | IL160968A0 (es) |
MX (1) | MXPA04003636A (es) |
MY (1) | MY139206A (es) |
NO (1) | NO341804B1 (es) |
NZ (1) | NZ532280A (es) |
PE (1) | PE20030476A1 (es) |
PL (2) | PL234541B1 (es) |
PT (1) | PT1438040E (es) |
RU (2) | RU2338528C2 (es) |
SI (1) | SI1438040T2 (es) |
TW (1) | TWI333861B (es) |
WO (1) | WO2003032978A1 (es) |
ZA (1) | ZA200401977B (es) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0124953D0 (en) | 2001-10-17 | 2001-12-05 | Novartis Ag | Organic Compounds |
AR045957A1 (es) * | 2003-10-03 | 2005-11-16 | Novartis Ag | Composicion farmaceutica y combinacion |
CN101014584A (zh) * | 2004-07-20 | 2007-08-08 | 特瓦药厂私人有限公司 | 结晶霉酚酸钠的制备方法 |
GB0419355D0 (en) * | 2004-08-31 | 2004-09-29 | Novartis Ag | Organic compounds |
US20060235009A1 (en) * | 2005-02-08 | 2006-10-19 | Richard Glickman | Treatment of vascular, autoimmune and inflammatory diseases using low dosages of IMPDH inhibitors |
EP1917010A2 (en) * | 2005-02-08 | 2008-05-07 | Aspreva Pharmaceuticals SA | Compositions and methods for treating vascular, autoimmune and inflammatory diseases |
BRPI0616640A2 (pt) * | 2005-09-30 | 2011-06-28 | Novartis Ag | combinação de compostos orgánicos |
US8597679B2 (en) | 2005-12-21 | 2013-12-03 | Basf Se | Fine-particle crosslinked polyvinylpyrrolidone as tablet disintegrant |
CN101378749A (zh) * | 2006-02-13 | 2009-03-04 | 诺瓦提斯公司 | 高剂量的麦考酚酸(mpa) |
WO2008148731A1 (de) | 2007-06-06 | 2008-12-11 | Basf Se | Pharmazeutische formulierung für die herstellung von schnell zerfallenden tabletten |
CN101707930B (zh) | 2007-06-06 | 2013-10-30 | 巴斯夫欧洲公司 | 用于制备快速崩解的片剂的药物配制剂 |
KR20100063059A (ko) * | 2007-08-13 | 2010-06-10 | 파나세아 바이오테크 리미티드 | 마이폴틱 장용정을 함유하는 서방출형 조성물 및 이의 조제방법 |
AU2009220779A1 (en) * | 2008-03-05 | 2009-09-11 | Panacea Biotec Limited | Modified release pharmaceutical compositions comprising mycophenolate and processes thereof |
CN102099029A (zh) * | 2008-07-09 | 2011-06-15 | 阿斯普瑞瓦国际公司 | 治疗眼部病症的霉酚酸钠的pH值特定溶液 |
WO2011046546A1 (en) * | 2009-10-13 | 2011-04-21 | Teva Pharmaceutical Industries Ltd. | Delayed release compositions |
US20110086102A1 (en) * | 2009-10-13 | 2011-04-14 | Teva Pharmaceutical Industries Ltd. | Delayed release compositions |
WO2011051967A2 (en) * | 2009-10-23 | 2011-05-05 | Alkem Laboratories Ltd | Pharmaceutical compositions comprising mycophenolate and processes for preparing thereof |
GB201100786D0 (en) | 2011-01-18 | 2011-03-02 | Ems Sa | Pharmaceutical compositions of immunosuppressants |
CN102793658A (zh) * | 2012-08-23 | 2012-11-28 | 无锡福祈制药有限公司 | 一种含有麦考酚酸或麦考酚酸盐的骨架型制剂及其包衣片 |
CN103845323B (zh) * | 2012-11-30 | 2018-02-02 | 重庆华邦制药有限公司 | 麦考酚酸及其盐肠溶制剂和制备方法 |
WO2014167442A1 (en) | 2013-03-26 | 2014-10-16 | Wockhardt Limited | Pharmaceutical compositions comprising mycophenolic acid or salts thereof |
CN106727403A (zh) * | 2017-01-03 | 2017-05-31 | 无锡福祈制药有限公司 | 一种麦考酚钠肠溶片及其制备方法 |
KR20190131036A (ko) * | 2017-03-13 | 2019-11-25 | 오카바 파마슈티컬즈 인코포레이티드 | 비-사람 포유동물에게 마이코페놀산 활성제를 전달하기 위한 방법 및 조성물 |
SG11202010322XA (en) * | 2018-06-14 | 2020-11-27 | Poxel | Film-coated tablet comprising a triazine derivative for use in the treatment of diabetes |
RU2723255C2 (ru) * | 2018-11-14 | 2020-06-09 | Общество с ограниченной ответственностью "Изварино Фарма" | Экструдат с микофенолятом натрия для получения пероральной твердой лекарственной формы |
JP2024506825A (ja) * | 2021-01-28 | 2024-02-15 | プリオセラ エスエーエス | S1p受容体調節剤による処置の方法 |
WO2022250977A1 (en) * | 2021-05-26 | 2022-12-01 | The Texas A&M University System | Biodegradable mucoadhesive pharmaceutical formulations and methods thereof |
CN117442580B (zh) * | 2023-12-21 | 2024-04-05 | 泊诺(天津)创新医药研究有限公司 | 一种高生物利用度麦考酚钠肠溶片及其制备方法 |
Family Cites Families (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1157099A (en) * | 1966-09-27 | 1969-07-02 | Ici Ltd | Fermentation Process |
GB1157100A (en) † | 1966-09-27 | 1969-07-02 | Ici Ltd | Pharmaceutical Compositions |
GB1203328A (en) * | 1968-06-04 | 1970-08-26 | Ici Ltd | Pharmaceutical compositions |
US3880995A (en) * | 1973-05-14 | 1975-04-29 | Lilly Co Eli | Treatment of arthritis with mycophenolic acid and derivatives |
JPS56127093A (en) * | 1980-03-10 | 1981-10-05 | Ajinomoto Co Inc | Preparation of mycophenolic acid |
US4959387A (en) * | 1986-01-23 | 1990-09-25 | Syntex (U.S.A.) Inc. | Mycophenolic acid derivatives in the treatment of rheumatoid arthritis |
US4725622A (en) * | 1986-01-23 | 1988-02-16 | Syntex (U.S.A.) Inc. | Mycophenolic acid derivatives in the treatment of rheumatoid arthritis |
US4753935A (en) * | 1987-01-30 | 1988-06-28 | Syntex (U.S.A.) Inc. | Morpholinoethylesters of mycophenolic acid and pharmaceutical compositions |
US4748173A (en) * | 1987-01-30 | 1988-05-31 | Syntex (U.S.A.) Inc. | Heterocyclic aminoalkyl esters of mycophenolic acid and derivatives thereof and pharmaceutical compositions |
US5177072A (en) * | 1987-01-30 | 1993-01-05 | Syntex (U.S.A.) Inc. | Treatment of autoimmune inflammatory, and psoriatic diseases with heterocyclic aminoalkyl esters of mycophenolic acid and derivatives |
WO1994012184A1 (en) * | 1992-11-24 | 1994-06-09 | Syntex (U.S.A.) Inc. | Use of mycophenolic acid, mycophenolate mofetil or derivate thereof to inhibit stenosis |
EP0670724A1 (en) * | 1992-11-24 | 1995-09-13 | Syntex (U.S.A.) Inc. | Use of mycophenolic acid, mycophenolate mofetil or derivate thereof to inhibit stenosis |
US5843479A (en) * | 1993-02-26 | 1998-12-01 | The Procter & Gamble Company | Bisacodyl dosage form with multiple enteric polymer coatings for colonic delivery |
US5656290A (en) * | 1993-02-26 | 1997-08-12 | The Procter & Gamble Company | Bisacodyl dosage form with multiple enteric polymer coatings for colonic delivery |
US5651983A (en) * | 1993-02-26 | 1997-07-29 | The Procter & Gamble Company | Bisacodyl dosage form for colonic delivery |
DK0686034T3 (da) * | 1993-02-26 | 2001-08-27 | Procter & Gamble | Bisacodyl-doseringsform |
US5455045A (en) * | 1993-05-13 | 1995-10-03 | Syntex (U.S.A.) Inc. | High dose formulations |
EP0721335B1 (en) * | 1993-10-01 | 2005-08-31 | Roche Palo Alto LLC | Mycophenolate mofetil high dose oral suspensions |
US5514663A (en) * | 1993-10-19 | 1996-05-07 | The Procter & Gamble Company | Senna dosage form |
AU7961094A (en) * | 1993-10-19 | 1995-05-08 | Procter & Gamble Company, The | Picosulphate dosage form |
US5482718A (en) * | 1994-03-23 | 1996-01-09 | Hoffmann-La Roche Inc. | Colon-targeted delivery system |
US5686106A (en) * | 1995-05-17 | 1997-11-11 | The Procter & Gamble Company | Pharmaceutical dosage form for colonic delivery |
ID18663A (id) * | 1996-04-12 | 1998-04-30 | Novartis Ag | Komposisi farmasi berlapis enterik |
DE60044717D1 (de) * | 1999-05-10 | 2010-09-02 | Paolo Brenner | Kombination von immunsuppressiven substanzen zur behandlung oder vorbeugung von transplantat abstossungen |
HUP9903226A2 (en) * | 1999-09-23 | 2002-08-28 | Gyogyszerki | Process for producing mycophenolic acid and derivatives thereof |
EP1259631B1 (en) * | 2000-02-29 | 2005-10-12 | Biocon Limited | Manufacture and purification of mycophenolic acid |
GB0124953D0 (en) | 2001-10-17 | 2001-12-05 | Novartis Ag | Organic Compounds |
GB0301259D0 (en) | 2003-01-20 | 2003-02-19 | Novartis Ag | Organic compounds |
-
2001
- 2001-10-17 GB GBGB0124953.1A patent/GB0124953D0/en not_active Ceased
-
2002
- 2002-10-15 TW TW091123694A patent/TWI333861B/zh not_active IP Right Cessation
- 2002-10-15 PE PE2002001013A patent/PE20030476A1/es not_active Application Discontinuation
- 2002-10-15 CO CO02092380A patent/CO5390076A1/es not_active Application Discontinuation
- 2002-10-15 AR ARP020103852A patent/AR036813A1/es not_active Application Discontinuation
- 2002-10-16 AU AU2002338897A patent/AU2002338897B2/en not_active Expired
- 2002-10-16 CA CA002460574A patent/CA2460574A1/en not_active Abandoned
- 2002-10-16 MY MYPI20023865A patent/MY139206A/en unknown
- 2002-10-16 HU HU0600451A patent/HU231114B1/hu unknown
- 2002-10-16 JP JP2003535782A patent/JP2005508959A/ja active Pending
- 2002-10-16 PT PT02777314T patent/PT1438040E/pt unknown
- 2002-10-16 SI SI200230646T patent/SI1438040T2/sl unknown
- 2002-10-16 AT AT02777314T patent/ATE374023T1/de active
- 2002-10-16 PL PL367738A patent/PL234541B1/pl unknown
- 2002-10-16 WO PCT/EP2002/011589 patent/WO2003032978A1/en active IP Right Grant
- 2002-10-16 IL IL16096802A patent/IL160968A0/xx unknown
- 2002-10-16 CN CNB028198611A patent/CN1310640C/zh not_active Expired - Fee Related
- 2002-10-16 PL PL415001A patent/PL415001A1/pl unknown
- 2002-10-16 RU RU2004115332/15A patent/RU2338528C2/ru not_active IP Right Cessation
- 2002-10-16 US US10/492,289 patent/US20050013859A1/en not_active Abandoned
- 2002-10-16 DE DE60222687.2T patent/DE60222687T3/de not_active Expired - Lifetime
- 2002-10-16 KR KR1020047005588A patent/KR100671367B1/ko active IP Right Review Request
- 2002-10-16 NZ NZ532280A patent/NZ532280A/en not_active IP Right Cessation
- 2002-10-16 MX MXPA04003636A patent/MXPA04003636A/es active IP Right Grant
- 2002-10-16 EP EP02777314.2A patent/EP1438040B2/en not_active Expired - Lifetime
- 2002-10-16 ES ES02777314T patent/ES2292819T5/es not_active Expired - Lifetime
- 2002-10-16 DK DK02777314.2T patent/DK1438040T4/da active
- 2002-10-16 BR BRPI0213355-5A patent/BR0213355A/pt active Search and Examination
- 2002-11-19 EC EC2002004342A patent/ECSP024342A/es unknown
- 2002-11-19 EC EC2002004341A patent/ECSP024341A/es unknown
-
2004
- 2004-03-11 ZA ZA200401977A patent/ZA200401977B/en unknown
- 2004-03-18 IL IL160968A patent/IL160968A/en active IP Right Grant
- 2004-05-03 NO NO20041785A patent/NO341804B1/no not_active IP Right Cessation
-
2005
- 2005-01-07 HK HK05100153A patent/HK1067861A1/xx not_active IP Right Cessation
-
2007
- 2007-08-13 RU RU2007130786/15A patent/RU2381026C2/ru not_active IP Right Cessation
- 2007-12-19 CY CY20071101618T patent/CY1107841T1/el unknown
-
2009
- 2009-01-23 JP JP2009012781A patent/JP2009137996A/ja active Pending
-
2010
- 2010-05-03 US US12/772,608 patent/US20100210717A1/en not_active Abandoned
-
2012
- 2012-05-04 AR ARP120101574A patent/AR085778A2/es not_active Application Discontinuation
- 2012-05-29 US US13/482,003 patent/US20120237601A1/en not_active Abandoned
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