EA202092461A1 - Наноэмульсии и способ их получения - Google Patents

Наноэмульсии и способ их получения

Info

Publication number
EA202092461A1
EA202092461A1 EA202092461A EA202092461A EA202092461A1 EA 202092461 A1 EA202092461 A1 EA 202092461A1 EA 202092461 A EA202092461 A EA 202092461A EA 202092461 A EA202092461 A EA 202092461A EA 202092461 A1 EA202092461 A1 EA 202092461A1
Authority
EA
Eurasian Patent Office
Prior art keywords
nanoemulsions
production
macroemulsions
values
preparation
Prior art date
Application number
EA202092461A
Other languages
English (en)
Inventor
Аньцзин Лоу
Цунлин Цюань
Тинуш Моаддел
Мария Бучалова
Original Assignee
Юнилевер Н.В.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Юнилевер Н.В. filed Critical Юнилевер Н.В.
Publication of EA202092461A1 publication Critical patent/EA202092461A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/06—Emulsions
    • A61K8/068—Microemulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/06—Emulsions
    • A61K8/064—Water-in-oil emulsions, e.g. Water-in-silicone emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A61K8/447—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof containing sulfur
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
    • A61K8/492—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid having condensed rings, e.g. indol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/673—Vitamin B group
    • A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/676—Ascorbic acid, i.e. vitamin C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/21—Emulsions characterized by droplet sizes below 1 micron
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95

Abstract

Описаны наноэмульсии и способ их получения. Наноэмульсии содержат агент для ухода за кожей в водной фазе, они получены из двух макроэмульсий, которые имеют различные значения pH.
EA202092461A 2018-05-23 2019-05-14 Наноэмульсии и способ их получения EA202092461A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18173916 2018-05-23
PCT/EP2019/062300 WO2019224048A1 (en) 2018-05-23 2019-05-14 Nanoemulsions and a method for making the same

Publications (1)

Publication Number Publication Date
EA202092461A1 true EA202092461A1 (ru) 2021-02-20

Family

ID=62567224

Family Applications (1)

Application Number Title Priority Date Filing Date
EA202092461A EA202092461A1 (ru) 2018-05-23 2019-05-14 Наноэмульсии и способ их получения

Country Status (9)

Country Link
US (1) US11540984B2 (ru)
EP (1) EP3773422B1 (ru)
JP (1) JP2021526127A (ru)
CN (1) CN112165927B (ru)
CA (1) CA3098981A1 (ru)
EA (1) EA202092461A1 (ru)
MX (1) MX2020012410A (ru)
WO (1) WO2019224048A1 (ru)
ZA (1) ZA202006323B (ru)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112021016260A2 (pt) * 2019-04-01 2021-10-13 Unilever Ip Holdings B.V. Composição cosmética e uso da composição

Family Cites Families (114)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB720561A (en) 1952-04-17 1954-12-22 Frederick Victor Wells Improvements in preparations for application to the hair and scalp
GB874368A (en) 1957-12-09 1961-08-02 Irwin Irville Lubowe Improvements in anti-seborrheic and scalp preparations
NL120093C (ru) 1958-07-24
GB987800A (en) 1962-02-13 1965-03-31 Shiseido Co Ltd Improvements in or relating to toilet preparations containing amino acids
GB1050756A (ru) 1964-09-10 1900-01-01
US3786076A (en) 1966-10-13 1974-01-15 J Morelle Lipoaminoacids
GB1235667A (en) 1967-07-19 1971-06-16 Nat Res Dev Improvements in or relating to sustained release preparations
JPS5032533B1 (ru) 1969-02-27 1975-10-22
BE793930A (fr) 1972-01-12 1973-05-02 Athlon Corp Composition pour le conditionnement de la peau
US4201235A (en) 1978-01-03 1980-05-06 Mare Corporation Amino acid-vitamin formulations for skin, hair and scalp conditioners
JPS61227515A (ja) 1985-04-01 1986-10-09 Shiseido Co Ltd 皮膚外用剤
US4826828A (en) 1985-04-22 1989-05-02 Avon Products, Inc. Composition and method for reducing wrinkles
US4707354A (en) 1985-06-17 1987-11-17 Alpen Tau, Inc. Mature skin treatment and protectant compositions and methods of using same
FR2608424B1 (fr) 1986-12-17 1989-06-16 Cazacou Cecilia Accelerateur de bronzage sans ecran solaire utilisant un complexe naturel favorisant la melanogenese
US4885157A (en) 1987-02-13 1989-12-05 Fiaschetti Mary G Dermal cosmetic composition and applications therefor
GB2212722B (en) 1987-11-25 1991-12-11 Theravit Limited Vitamin compositions
US5133958A (en) 1989-04-20 1992-07-28 Erwin Stuckler Agent for nail, skin and hair care
FR2660196A1 (fr) 1990-03-28 1991-10-04 Courmontagne Albert Procede de fabrication d'extrait cellulaire hydrosoluble d'embryons d'óoeuf et produit obtenu.
US5198465A (en) 1991-06-19 1993-03-30 Dioguardi Francesco S Compositions based on amino acids for preventing and treating precursor deficiencies in the synthesis of collagen
WO1993000156A1 (en) 1991-06-29 1993-01-07 Miyazaki-Ken Monodisperse single and double emulsions and production thereof
US5254331A (en) 1991-09-12 1993-10-19 Chanel, Inc. Skin cream composition
TW233264B (ru) 1992-02-03 1994-11-01 Otsuka Pharma Co Ltd
IL101007A (en) 1992-02-18 1997-08-14 Pharmos Ltd Dry stable compositions prepared by lyophilization
DE4328871A1 (de) 1993-08-27 1995-03-02 Beiersdorf Ag Mittel gegen empfindliche, hyperreaktive Hautzustände, atopische Dermatiden, Pruritus, Psoriasis Prurigo, Photodermatosen und Ichthyosis
US5416075A (en) 1993-11-30 1995-05-16 Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. Biospecific emulsions
FR2718637A1 (fr) 1994-04-15 1995-10-20 Oreal Composition cosmétique à appliquer sur l'ongle.
DE19509354A1 (de) 1994-12-08 1996-06-13 Klett Loch Lore M Kombinationspräparat zur Förderung des Haarwachstums und ggf. des Haut- und Nagelwachstums sowie zur Verhinderung bzw. zur Beseitigung von Haarausfall
DE19510732C1 (de) 1995-03-24 1996-05-23 Tscheulin Rothal Gmbh Verfahren zum Verschließen einer Behälteröffnung, Behälter mit einem Behälterverschluß sowie Deckelmaterial zur Herstellung eines solchen Behälterverschlusses
US5738051A (en) 1996-03-06 1998-04-14 Outboard Marine Corporation Four-cycle marine engine
TW592713B (en) 1998-05-11 2004-06-21 Ciba Sc Holding Ag Use of nanodispersions in cosmetic end formulations
US7381423B2 (en) 1998-05-11 2008-06-03 Ciba Specialty Chemicals Corp. Use of nanodispersions in cosmetic end formulations
DE19831798A1 (de) 1998-07-15 2000-01-27 Mandorlo Investment Gmbh Luxem Mittel zur Pflege und/oder Behandlung von Haut und Gewebe
US6703031B1 (en) 1998-10-09 2004-03-09 Ajinomoto Co., Inc. Cysteine derivatives
US6149925A (en) 1998-11-05 2000-11-21 Color Access, Inc. Topical compositions for enhancing glutathione production
CA2388161A1 (en) 1999-10-22 2001-04-26 Unilever Plc Stable multiple emulsion cosmetic composition comprising high levels of surfactant
AU2001265151A1 (en) 2000-05-31 2001-12-11 Encelle, Inc. Method of stimulating hair growth
DE10130963A1 (de) 2001-06-27 2003-01-16 Beiersdorf Ag Verwendung von Bis-Resorcinyltriazinderivaten zur Verbesserung der Wirksamkeit von lipophilen Wirkstoffen in kosmetischen oder dermatologischen Zubereitungen
KR100941662B1 (ko) 2001-10-09 2010-02-11 가부시키가이샤환케루 글루타티온 증강용 조성물
FR2832074B1 (fr) 2001-11-09 2004-08-27 Rhodia Chimie Sa Emulsions multiples comprenant des particules de dimensions nanometriques de surface modifie a titre d'agents stabilisants
US6858217B2 (en) 2002-03-22 2005-02-22 Unilever Home & Personal Care Usa Division Of Conopco, Inc. Stabilization of terpenoids in cosmetic compositions
US6869598B2 (en) 2002-03-22 2005-03-22 Unilever Home & Personal Care Usa Division Of Conopco, Inc. Stabilization of sunscreens in cosmetic compositions
US6863897B2 (en) 2002-03-22 2005-03-08 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Stabilization of resorcinol derivatives in cosmetic compositions
US20030232091A1 (en) 2002-06-17 2003-12-18 Adi Shefer Stabilized retinol for cosmetic dermatological, and pharmaceutical compositions, and use thereof
US6592908B1 (en) 2002-09-23 2003-07-15 Albert Crum Nutritional or therapeutic compositions
WO2004100904A1 (en) 2003-05-07 2004-11-25 The Lubrizol Corporation Emulsifiers for multiple emulsions
KR101002433B1 (ko) 2003-09-19 2010-12-17 주식회사 엘지생활건강 비타민 ａ 및 그의 유도체, 및 펩타이드를 포함하는 나노에멀젼, 및 이를 포함하는 주름 개선용 화장료 조성물
DE10351644A1 (de) 2003-11-05 2005-06-09 Bayer Technology Services Gmbh Verfahren zur Herstellung von lagerstabilen multiplen Emulsionen
JP4099716B2 (ja) 2004-02-09 2008-06-11 住友電装株式会社 高圧コネクタ
US20050192229A1 (en) 2004-02-27 2005-09-01 Perricone Nicholas V. Topical glutathione treatments
EP1598060A1 (en) 2004-05-18 2005-11-23 Nestec S.A. Oil-in-water emulsion for delivery
US20050271726A1 (en) 2004-06-02 2005-12-08 Albert Crum Immune enhancing compositions and methods of use thereof
KR100623013B1 (ko) 2004-09-04 2006-09-19 김영대 나노에멀션, 그의 용도 및 제조방법
KR100638602B1 (ko) 2004-09-16 2006-10-26 한국콜마 주식회사 친유형으로 변형된 폴리프록토스계 고분자 유화제를이용한 수중유중수형 다중에멀젼 상의 화장료 및 그제조방법
US7300649B2 (en) 2005-02-11 2007-11-27 Genepharm, Inc. Cosmetic and cosmeceutical compositions for restoration of skin barrier function
EP1861194A2 (en) 2005-03-04 2007-12-05 The President and Fellows of Harvard College Method and apparatus for forming multiple emulsions
EP1888020B1 (en) 2005-04-28 2009-12-16 Basf Se Use of benzotriazole derivatives for photostabilisation
EP1937366B1 (en) 2005-10-14 2011-12-14 Symrise AG Synergistic mixtures of bisabolol and ginger extract
CN101360481A (zh) 2005-11-22 2009-02-04 雀巢技术公司 水包油乳液及其用于功能性输送的用途
CN101360424B (zh) 2005-11-22 2013-05-15 雀巢技术公司 易分散的油脂相
US8147815B2 (en) 2005-12-16 2012-04-03 Celmatrix Corporation Topical administration carrier composition and therapeutic formulations comprising same
ITMI20060618A1 (it) 2006-03-31 2007-10-01 Enitecnologie Spa Procedimento per la preparazione di nanoemulsioni acqua ion olio e olio in acqua
AU2007353340A1 (en) * 2006-12-01 2008-11-20 Anterios, Inc. Peptide nanoparticles and uses therefor
US20120034183A1 (en) 2006-12-19 2012-02-09 Michael Cohen Compositions and methods for growing embryonic stem cells
US20080311058A1 (en) 2007-06-18 2008-12-18 Connopco, Inc., D/B/A Unilever Stable high internal phase emulsions and compositions comprising the same
US8440172B2 (en) 2007-07-09 2013-05-14 Symrise Ag Stable soluble salts of phenylbenzimidazole sulfonic acid at PHS at or below 7.0
BRPI0814745A2 (pt) 2007-08-03 2014-10-07 Aminotech As Composição de produto.
US20100322876A1 (en) 2007-09-14 2010-12-23 L'oreal Compositions and methods for treating keratinous substrates
ES2389749T3 (es) 2007-09-28 2012-10-31 Unilever N.V. Composición de emulsión estabilizada con partículas
FR2924033B1 (fr) 2007-11-22 2013-07-05 Nat Inov Procede d'obtention d'une dispersion d'au moins une huile essentielle dans l'eau.
DK2222340T3 (da) 2007-11-28 2014-04-14 Commw Scient Ind Res Org Nanoemulsioner
CN101214199B (zh) 2007-12-29 2010-06-16 广东拉芳日化有限公司 纳米活性祛痘化妆品组合物
JP2009242321A (ja) 2008-03-31 2009-10-22 Shiseido Co Ltd 皮膚外用剤
US8425882B2 (en) 2008-04-01 2013-04-23 Conopco, Inc. In-shower and bath compositions
US20090263513A1 (en) 2008-04-18 2009-10-22 Jan Marini Cosmetic skin lightening formulation
DK2337627T3 (da) 2008-09-18 2013-09-08 Univ Eindhoven Tech Fremgangsmåde til fremstilling af monodispergerede emulsioner
NL2002046C (en) 2008-10-01 2010-04-02 Friesland Brands Bv Double emulsion and method to produce such.
CN101401775B (zh) 2008-11-18 2010-08-25 董萍 被动靶向夜用和日用皮肤美白功效纳米乳及其制备方法
CN101530377B (zh) 2009-03-11 2011-04-20 董萍 皮肤外用祛斑功效纳米乳组合产品及其制备方法
US8299127B2 (en) 2009-03-11 2012-10-30 Conopco, Inc. Method and composition for evenly applying water soluble actives
US20100305169A1 (en) 2009-03-23 2010-12-02 Larry Rich Robinson Personal-care composition comprising a cationic active
JP5032533B2 (ja) 2009-06-09 2012-09-26 富士通テレコムネットワークス株式会社 フレーム伝送装置及びフレーム廃棄数測定方法
CA2778251C (en) 2009-11-06 2015-12-22 The Procter & Gamble Company High efficiency capsules comprising benefit agent
CN101721930B (zh) 2009-12-15 2011-11-30 山东大学 一种正电纳米乳液的低能制备方法
BRPI0905347C1 (pt) 2009-12-15 2021-05-25 Univ Federal Rio Grande Sul nanocápsulas poliméricas deformáveis no encapsulamento de bioativos
CN102150866B (zh) 2010-02-12 2014-10-15 悠哈味觉糖有限公司 含胱氨酸复合体及其制造方法
CN201799243U (zh) 2010-06-13 2011-04-20 中国人民解放军第三军医大学 一种用一步法和低能乳化法制备纳米乳的搅拌机
US8895628B2 (en) 2010-10-25 2014-11-25 Johnson & Johnson Consumer Companies, Inc. Compositions comprising a retinoid and an NFkB-inhibitor and their methods of use
JP6378878B2 (ja) 2011-01-07 2018-08-22 アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ メラニン改変組成物および使用方法
HUE042252T2 (hu) 2011-03-21 2019-06-28 Broda Tech Co Ltd Fordítottan hõ-reverzibilis hidrogél kompozíciók
US8795643B1 (en) 2011-04-29 2014-08-05 Michael Mark Anthony Method of preparing a hair treatment formulation comprising nanoparticles in solution and method of hair treatment utilizing a treatment formulation comprising nanoparticles in solution
US9345773B2 (en) 2011-06-23 2016-05-24 Indian Institute Of Technology Kanpur PVA-boronic acid containing copolymer compositions for protein delivery
US10639252B2 (en) 2011-09-23 2020-05-05 Allergan, Inc. Compositions for skin exfoliation and use thereof
BR112014012753A8 (pt) 2011-12-20 2017-06-20 Unilever Nv composição para pele e método de hidratação da pele
CN102755847B (zh) 2012-07-17 2014-08-06 山东大学 一种油包水型纳米乳液的低能耗制备方法
JP6115086B2 (ja) 2012-11-13 2017-04-19 味の素株式会社 アミノ酸化合物の酢酸塩を含有する化粧料組成物
WO2014131871A2 (en) 2013-02-28 2014-09-04 L'oreal Cosmetic composition in the form of an oil-in-water nanoemulsion for the oxidation dyeing of keratin fibres, and process for the same
CA3167320A1 (en) 2013-03-08 2014-09-12 Unilever Global Ip Limited Resorcinol compounds for dermatological use
JP6039484B2 (ja) 2013-03-29 2016-12-07 富士フイルム株式会社 組成物及び化粧料
US9833403B2 (en) 2013-06-03 2017-12-05 Huiwen Liu Nanoparticles and nanoemulsions
US20140375562A1 (en) 2013-06-21 2014-12-25 Daniel Robert Pereira System and Process for Human-Computer Interaction Using a Ballistic Projectile as an Input Indicator
JP6212320B2 (ja) 2013-08-01 2017-10-11 ポーラ化成工業株式会社 皮膚外用剤
WO2015066777A1 (en) 2013-11-08 2015-05-14 L'oreal Cosmetic compositions in the form of oil-in-water nanoemulsions, comprising solid fatty alcohol(s), liquid fatty ester(s), other oil(s) and non-ionic surfactant(s)
JP6510177B2 (ja) 2014-04-01 2019-05-08 ロレアル ナノ又はマイクロエマルションの形態の組成物
JP2016056111A (ja) 2014-09-05 2016-04-21 ロレアル ナノエマルションを調製するための方法
CN107407079A (zh) 2014-11-24 2017-11-28 哈佛学院院长及董事 含硬化部分的多重乳液
US9506019B2 (en) 2015-01-28 2016-11-29 The Procter & Gamble Company Silicone nanoemulsion comprising alkylene glycol alkyl ether
KR20160123753A (ko) 2015-04-17 2016-10-26 (주)제이준코스메틱 피부미백용 조성물
CN104874305A (zh) 2015-04-28 2015-09-02 扬州大学 一种o/w纳米乳液及其低能制备方法
CN105148758B (zh) 2015-08-20 2017-11-14 扬州大学 一种快速制备纳米乳液的方法
US9872832B2 (en) 2015-10-23 2018-01-23 LG Bionano, LLC Nanoemulsions having reversible continuous and dispersed phases
CN105919827A (zh) 2016-06-01 2016-09-07 北京希诺赛尔健康科技推广有限公司 一种具有保湿抗皱作用的护肤组合物
EP3558245B1 (en) * 2016-12-21 2024-02-07 Unilever IP Holdings B.V. Topical skin lightening additive and composition with amino acids and ppar activating fatty acids
CN109199878A (zh) 2018-09-26 2019-01-15 华南理工大学 一种美白防晒w/o/w多重乳液及其制备方法
CN109276515B (zh) 2018-10-30 2021-07-06 广州瑾洋化妆品有限公司 一种含有生物活性胶原肽的组合物及其制备方法与应用

Also Published As

Publication number Publication date
EP3773422B1 (en) 2021-11-10
MX2020012410A (es) 2022-03-29
CN112165927A (zh) 2021-01-01
ZA202006323B (en) 2022-01-26
EP3773422A1 (en) 2021-02-17
JP2021526127A (ja) 2021-09-30
US20210205186A1 (en) 2021-07-08
CA3098981A1 (en) 2019-11-28
WO2019224048A1 (en) 2019-11-28
US11540984B2 (en) 2023-01-03
CN112165927B (zh) 2024-01-30

Similar Documents

Publication Publication Date Title
MD3443009T2 (ro) Anticorpi anti-TIM-3 și compoziții
PH12020500231A1 (en) Interleukin-21 muteins and methods of treatment
ECSP18095014A (es) Proteínas de unión biespecíficas que se unen a una proteína inmunomoduladora y a un antígeno tumoral
EA201891339A1 (ru) Водный фармацевтический препарат, который содержит антитело к pd-l1 авелумаб
MD3273992T2 (ro) Anticorpi pentru ICOS
MD3370768T2 (ro) Anticorpi care se leagă specific la PD-1 și utilizări ale lor
EP4219724A3 (en) Compositions and methods for treating non-age-associated hearing impairment in a human subject
CL2019002626A1 (es) Anticuerpos anti-par2 y usos de los mismos.
EA201890630A1 (ru) Антитела против pd-1 и способы их применения
EA202092435A3 (ru) Моноклональные антитела против bcma
EA201692502A1 (ru) Лечение миелом
MX2020000713A (es) Metodos de aferesis y sus usos.
EA201891342A1 (ru) Изоиндольные соединения
EA201892287A1 (ru) Фармацевтические комбинации для лечения рака
MX2019010367A (es) Formulacion acuosa de anticuerpo anti ligando 1 de muerte programada (pd-l1).
MD3522880T2 (ro) Metode de tratare a leziunilor renale acute
EA202091366A1 (ru) Обесцвеченный изолят рапсового белка
EA201791992A1 (ru) Ингибиторы грелин-o-ацилтрансферазы
CR20170040A (es) Anticuerpos anti proteína similar a angiopoyetina 4 y métodos de uso
BR112018015343A2 (pt) oxidação de amido
EA201891610A1 (ru) Производные 3-(карбоксиэтил)-8-амино-2-оксо-1,3-диазаспиро[4.5]декана
EA202092461A1 (ru) Наноэмульсии и способ их получения
CO2018003684A2 (es) Redispersión de esquizofilán
JOP20190164B1 (ar) تركيبات وطرق لعلاج داء فاربر
EA201892641A1 (ru) Эмульсия масло-в-воде, содержащая пшеничную муку и физически модифицированный крахмал