CN105919827A - 一种具有保湿抗皱作用的护肤组合物 - Google Patents

一种具有保湿抗皱作用的护肤组合物 Download PDF

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CN105919827A
CN105919827A CN201610379474.0A CN201610379474A CN105919827A CN 105919827 A CN105919827 A CN 105919827A CN 201610379474 A CN201610379474 A CN 201610379474A CN 105919827 A CN105919827 A CN 105919827A
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skin care
vitamin
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杨振亚
韩之海
刘玢
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Beijing Sealop Purcell Health Technology Development Co Ltd
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    • A61K8/00Cosmetics or similar toiletry preparations
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    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
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    • A61K8/442Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof substituted by amido group(s)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A61K8/447Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof containing sulfur
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
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    • AHUMAN NECESSITIES
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Abstract

本发明公开了一种具有保湿抗皱作用的护肤组合物,该组合物以无菌去离子水为溶剂,溶质为包含甘氨酸、苯丙氨酸、丙氨酸、脯氨酸、谷氨酰胺、丝氨酸、精氨酸、苏氨酸、天冬酰胺、色氨酸、天冬氨酸、酪氨酸、半胱氨酸、缬氨酸、胱氨酸、维生素H、谷氨酸、烟酰胺、组氨酸、维生素B6、异亮氨酸、维生素B2、亮氨酸、维生素B1在内的氨基酸、维生素与微量元素。具有良好的保湿抗皱作用,且具有如下优点:安全无副作用、滋养肌肤、具有良好的透皮能力。

Description

一种具有保湿抗皱作用的护肤组合物
技术领域
本发明涉及护肤品领域,具体涉及一种具有保湿抗皱作用的护肤组合物。
背景技术
随着生活水平的不断提高,消费者对美容以及皮肤的护理和保养也越发的重视。但人体的皮肤与外界环境直接接触,由于辐射、空气污染、细胞代谢等原因,经常会出现皮肤老化加速、皱纹增多、皮肤失去弹性的现象,部分人缺乏护肤意识或使用不适合自己的护肤品,导致肌肤问题愈发严重。如对于皮肤敏感的人群,护肤品中的添加剂会刺激皮肤引起皮肤过敏。孕妇及婴儿用的护肤品很少含有刺激性的添加物,皮肤敏感的人群会选用孕妇及婴儿用的护肤品来代用,但这类护肤品通常只具有保湿作用,而不具有抗皱作用。
目前随着技术的进步,越来越多的人倾向于科学的使用护肤品,对于具有保湿抗皱作用的护肤品,不仅注重其保湿抗皱的效果,对安全性的要求越来越高。
本发明的目的在于提供一种能保证保湿抗皱效果,又不会对皮肤产生刺激的具有保湿抗皱作用的护肤组合物。
发明内容
为了实现上述目的,本发明的第一技术方案为一种具有保湿抗皱作用的护肤组合物,其特征在于:包括,溶质和溶剂,每100g溶剂中的溶质的添加量的中心值为:甘氨酸18.75mg;丙氨酸4.45mg;谷氨酰胺542mg;精氨酸147.5mg;天冬酰胺7.5mg;天冬氨酸6.65mg;半胱氨酸17.56mg;胱氨酸31.29mg;谷氨酸7.35mg;组氨酸31.48mg;异亮氨酸54.47mg;亮氨酸59.95mg;赖氨酸91.25mg;苯丙氨酸35.48mg;脯氨酸35.48mg;丝氨酸26.25mg;苏氨酸53.45mg;色氨酸9.02mg;酪氨酸55.79mg;缬氨酸52.85mg;维生素H0.0035mg;烟酰胺2.02mg;维生素B6 2.031mg;维生素B2 0.219mg;维生素B1 2.17mg;肌醇12.6mg。
第二技术方案基于第一技术方案,其特征在于:所述溶剂为无菌去离子水。
第三技术方案基于第二技术方案,其特征在于:将无菌去离子水投入带有搅拌装置的小型反应釜中,然后再分别将溶质按比例投入到反应釜中,在恒温的条件下,搅拌制成。
第四技术方案基于第三技术方案,其特征在于:在37°的恒温的条件下,搅拌1小时制成。
具体实施方式
为使本发明更加容易理解,下面结合具体实施方式,进一步阐述本发明的结构。这些实施例仅用于说明本发明而不用于限制本发明的范围。
本实施方式中,具有保湿抗皱作用的护肤组合物包括溶质和溶剂,溶剂选用无菌去离子水,并将溶质按下述配比添加到溶剂中:
该组合物充分利用各组分之间的相互作用,克服它们单独使用时效果不佳的缺点,提高了保湿抗皱的效果。由于利用保湿抗皱的效果是利用各组分之间的相互作用,而不是对皮肤有刺激性的添加剂,在保证保湿抗皱效果的同时也保证其对皮肤安全性。
与利用添加剂的组合物相比,本发明的组合物具有如下优点:
(1)该组分由氨基酸、维生素等组成,不含有任何带有肌肤刺激性的成分,不会使肌肤过敏,安全无副作用。
(2)保湿效果好。该组合物含多种氨基酸保湿成分,可以提高肌肤的保湿效果,肌肤不会因气候干燥而快速失水。
(3)滋养肌肤。该组合物能够修复被损伤的细胞,使细胞得到滋养,恢复皮肤光泽和弹性。
(4)对细胞膜具有亲和力,具有良好的透皮能力。该组合物接触皮肤后,能够快速穿过细胞膜,使有效成分进入细胞内部。
(5)抗皱效果好。该组合物能够促进胶原蛋白的合成,增加皮肤弹性。以下通过实施例对本发明的效果做进一步说明。
实施例
实施例:制取1千克护肤剂。
先取无菌去离子水1千克,投入带有搅拌装置的小型反应釜中,然后再分别将溶质按下表添加量投入到反应釜中。
甘氨酸 187.5mg 苯丙氨酸 354.8mg
丙氨酸 44.5mg 脯氨酸 172.5mg
谷氨酰胺 5420mg 丝氨酸 262.5mg
精氨酸 1475mg 苏氨酸 534.5mg
天冬酰胺 75mg 色氨酸 90.2mg
天冬氨酸 66.5mg 酪氨酸 557.9mg
半胱氨酸 175.6mg 缬氨酸 528.5mg
胱氨酸 312.9mg 维生素H 0.035mg
谷氨酸 73.5mg 烟酰胺 20.2mg
组氨酸 314.8mg 维生素B6 20.31mg
异亮氨酸 544.7mg 维生素B2 02.19mg
亮氨酸 599.5mg 维生素B1 21.7mg
赖氨酸 912.5mg 肌醇 126mg
而后在37摄氏度恒温下,搅拌1小时,最后通过罐装设备罐装即成产品。恒温的温度和搅拌的时间并不限于37摄氏度和1小时,可以根据需要改变。
以下通过实验例观察本发明所述组合物的保湿抗皱作用效果。
实验例
1、志愿者选择:选择200例肌肤干燥粗糙、出现皱纹的女性志愿者,分为实验组和对照组,每组100例。
2、实验方法:实验组涂抹本发明实施例的组合物,每天早晚各1次,每次于干燥及皱纹处涂抹2mL,连续使用28天,期间停止使用其他中西药及保健品。对照组涂抹成分为无菌去离子水的安慰剂,每天早晚各1次,每次于干燥及皱纹处涂抹2mL,连续使用28天,期间停止使用其他中西药及保健品。
3、主观统计结果:本发明具有良好的保湿抗皱作用,实验组明显感觉肌肤皱纹改善并且水润的人为88人,感觉不明显的为12人;对照组明显感觉肌肤皱纹改善并且水润的人为7人,感觉不明显的为93人,两组存在明显差异。
4、测试数据:利用德国Courage Khazaka公司MC760型皮肤测试仪分别对实验组和对照组志愿者的肌肤进行了实验前后的含水度及纹理度测试,平均数据如下。
上述数据表明,两组存在明显差异,本发明具有良好的保湿抗皱作用,并且对皮肤不具有刺激性,不会引发皮肤问题,在保证保湿抗皱效果的同时也保证其安全性和有效性。
上述实施例仅仅是为清楚地说明本发明所作的举例,本发明的实施方式并不受上述实施例的限制。对于本领域的技术人员而言,在上述说明基础上可以做出其它不同形式的变化。因此其它任何不背离本发明原理的改变、修饰、替代、组合均包含在本发明的保护范围之内,如本实施方式中的各组分的配比(添加量)只是中心值,本领域的技术人员可以根据其掌握的知识做出调整,使配比增加或减少。

Claims (4)

1.一种具有保湿抗皱作用的护肤组合物,其特征在于:包括,溶质和溶剂,每100g溶剂中的溶质的添加量的中心值为:甘氨酸18.75mg;丙氨酸4.45mg;谷氨酰胺542mg;精氨酸147.5mg;天冬酰胺7.5mg;天冬氨酸6.65mg;半胱氨酸17.56mg;胱氨酸31.29mg;谷氨酸7.35mg;组氨酸31.48mg;异亮氨酸54.47mg;亮氨酸59.95mg;赖氨酸91.25mg;苯丙氨酸35.48mg;脯氨酸35.48mg;丝氨酸26.25mg;苏氨酸53.45mg;色氨酸9.02mg;酪氨酸55.79mg;缬氨酸52.85mg;维生素H0.0035mg;烟酰胺2.02mg;维生素B6 2.031mg;维生素B2 0.219mg;维生素B12.17mg;肌醇12.6mg。
2.根据权利要求1记载的一种具有保湿抗皱作用的护肤组合物,其特征在于:所述溶剂为无菌去离子水。
3.根据权利要求2记载的一种具有保湿抗皱作用的护肤组合物,其特征在于:将无菌去离子水投入带有搅拌装置的小型反应釜中,然后再分别将溶质按比例投入到反应釜中,在恒温的条件下,搅拌制成。
4.根据权利要求3记载的一种具有保湿抗皱作用的护肤组合物,其特征在于:在37°的恒温的条件下,搅拌1小时制成。
CN201610379474.0A 2016-06-01 2016-06-01 一种具有保湿抗皱作用的护肤组合物 Pending CN105919827A (zh)

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Application publication date: 20160907