EA201590309A1 - Антибактериальная композиция для местного применения - Google Patents

Антибактериальная композиция для местного применения

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Publication number
EA201590309A1
EA201590309A1 EA201590309A EA201590309A EA201590309A1 EA 201590309 A1 EA201590309 A1 EA 201590309A1 EA 201590309 A EA201590309 A EA 201590309A EA 201590309 A EA201590309 A EA 201590309A EA 201590309 A1 EA201590309 A1 EA 201590309A1
Authority
EA
Eurasian Patent Office
Prior art keywords
antibacterial composition
infections
local application
purulent
fakalkallkalkal
Prior art date
Application number
EA201590309A
Other languages
English (en)
Other versions
EA029484B1 (ru
Inventor
Джанфранко Де Паоли Амбрози
Original Assignee
Дженераль Топикс С.Р.Л.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Дженераль Топикс С.Р.Л. filed Critical Дженераль Топикс С.Р.Л.
Publication of EA201590309A1 publication Critical patent/EA201590309A1/ru
Publication of EA029484B1 publication Critical patent/EA029484B1/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/225—Polycarboxylic acids
    • A—HUMAN NECESSITIES
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    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/231—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having one or two double bonds
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    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/232—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
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    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
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    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
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    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
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    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Birds (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Zoology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Настоящее изобретение относится к антибактериальной композиции, преимущественно для местного применения, содержащей триэтилцитрат и пептид, состоящий из последовательности 15 аминокислот FAKALKALLKALKAL-NH2, где F представляет собой фенилаланин, А представляет собой аланин, K представляет собой лизин и L представляет собой лейцин, в частности для лечения угрей, гнойного или негнойного гидраденита, атопического дерматита, характеризующегося колонизацией Staphylococcus aureus, импетиго, межпальцевых инфекций, фолликулита, фурункулов, посттравматических инфекций и кожных инфекций после ожогов.
EA201590309A 2012-08-01 2013-07-29 Антибактериальная композиция для местного применения EA029484B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000126A ITBS20120126A1 (it) 2012-08-01 2012-08-01 Composizione antibatterica per uso topico
PCT/IB2013/056199 WO2014020516A1 (en) 2012-08-01 2013-07-29 Antibacterial composition for topical use

Publications (2)

Publication Number Publication Date
EA201590309A1 true EA201590309A1 (ru) 2015-06-30
EA029484B1 EA029484B1 (ru) 2018-04-30

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EA201590309A EA029484B1 (ru) 2012-08-01 2013-07-29 Антибактериальная композиция для местного применения

Country Status (19)

Country Link
US (1) US9511112B2 (ru)
EP (1) EP2922537B1 (ru)
JP (1) JP2015525778A (ru)
KR (1) KR20150040972A (ru)
CN (1) CN104822375A (ru)
AU (1) AU2013298182B2 (ru)
CA (1) CA2880778C (ru)
EA (1) EA029484B1 (ru)
ES (1) ES2685972T3 (ru)
IL (1) IL237035B (ru)
IN (1) IN2015MN00433A (ru)
IT (1) ITBS20120126A1 (ru)
MA (1) MA37869B1 (ru)
MX (1) MX347281B (ru)
MY (1) MY167610A (ru)
PL (1) PL2922537T3 (ru)
SG (1) SG11201500806RA (ru)
UA (1) UA113015C2 (ru)
WO (1) WO2014020516A1 (ru)

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US11174288B2 (en) 2016-12-06 2021-11-16 Northeastern University Heparin-binding cationic peptide self-assembling peptide amphiphiles useful against drug-resistant bacteria
CN107383166B (zh) * 2017-08-07 2020-10-23 温州千瑞生物科技有限公司 对痤疮杆菌敏感的肽
CN108553411B (zh) * 2018-07-25 2020-05-12 成都卓阳生物科技有限公司 壬二酸凝胶剂及其制备方法和应用
CN109776573A (zh) * 2018-08-16 2019-05-21 上海金城药业有限公司 头孢羟氨苄制剂治疗女性生殖系统感染的新适应症
CN109122687B (zh) * 2018-08-25 2022-01-18 浙江工业大学 乙醇酸盐配合物杀菌剂及其应用
US20200345611A1 (en) * 2019-04-30 2020-11-05 Evonik Operations Gmbh Composition comprising at least one ceramide, at least one sphingoid base and triethyl citrate
CN110614080A (zh) * 2019-09-30 2019-12-27 重庆大学 一种双金属氮掺杂磁性多孔碳材料在吸附环丙沙星中的应用
CN115778949A (zh) * 2022-12-15 2023-03-14 复旦大学附属华山医院 用于抑制产kpc酶肺炎克雷伯菌的组合物、药物及其应用

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IL237035A0 (en) 2015-03-31
EA029484B1 (ru) 2018-04-30
ES2685972T3 (es) 2018-10-15
MY167610A (en) 2018-09-20
AU2013298182A1 (en) 2015-03-12
EP2922537A1 (en) 2015-09-30
MA37869B1 (fr) 2016-10-31
MX2015001451A (es) 2015-06-05
AU2013298182B2 (en) 2017-11-23
JP2015525778A (ja) 2015-09-07
CA2880778C (en) 2020-01-07
KR20150040972A (ko) 2015-04-15
IN2015MN00433A (ru) 2015-09-11
CN104822375A (zh) 2015-08-05
WO2014020516A1 (en) 2014-02-06
EP2922537B1 (en) 2018-06-13
PL2922537T3 (pl) 2018-11-30
MX347281B (es) 2017-04-21
UA113015C2 (uk) 2016-11-25
IL237035B (en) 2019-05-30
US20150209405A1 (en) 2015-07-30
US9511112B2 (en) 2016-12-06
SG11201500806RA (en) 2015-05-28
CA2880778A1 (en) 2014-02-06

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