MX2018011249A - Composiciones topicas no acuosas que comprenden una salicilanilida halogenada. - Google Patents

Composiciones topicas no acuosas que comprenden una salicilanilida halogenada.

Info

Publication number
MX2018011249A
MX2018011249A MX2018011249A MX2018011249A MX2018011249A MX 2018011249 A MX2018011249 A MX 2018011249A MX 2018011249 A MX2018011249 A MX 2018011249A MX 2018011249 A MX2018011249 A MX 2018011249A MX 2018011249 A MX2018011249 A MX 2018011249A
Authority
MX
Mexico
Prior art keywords
halogenated salicylanilide
topical compositions
aqueous topical
compositions
prevention
Prior art date
Application number
MX2018011249A
Other languages
English (en)
Inventor
Li Ping
otto alexander sommer Morten
Hasling Frandsen Camilla
Mørck Nielsen Hanne
Alexandra Priemel Petra
Rades Thomas
Original Assignee
Antibiotx As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Antibiotx As filed Critical Antibiotx As
Publication of MX2018011249A publication Critical patent/MX2018011249A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203—Retinoic acids ; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/327—Peroxy compounds, e.g. hydroperoxides, peroxides, peroxyacids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/609—Amides, e.g. salicylamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invención se refiere a composiciones tópicas no acuosas que comprenden una salicilanilida halogenada y al uso de tales composiciones en el tratamiento tópico o prevención de enfermedades e infecciones, particularmente afecciones causadas por bacterias Grampositivas, por ejemplo, el tratamiento tópico o prevención de infecciones cutáneas como el acné, la dermatitis atópica y el impétigo; también se describen métodos para preparar la composición de gel.
MX2018011249A 2016-03-16 2017-03-15 Composiciones topicas no acuosas que comprenden una salicilanilida halogenada. MX2018011249A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1604484.4A GB201604484D0 (en) 2016-03-16 2016-03-16 Topical antibacterial compositions
PCT/EP2017/056083 WO2017157997A1 (en) 2016-03-16 2017-03-15 Non-aqueous topical compositions comprising a halogenated salicylanilide

Publications (1)

Publication Number Publication Date
MX2018011249A true MX2018011249A (es) 2019-09-16

Family

ID=55952410

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018011249A MX2018011249A (es) 2016-03-16 2017-03-15 Composiciones topicas no acuosas que comprenden una salicilanilida halogenada.

Country Status (13)

Country Link
US (1) US20190151231A1 (es)
EP (1) EP3429691B1 (es)
JP (1) JP2019508463A (es)
KR (1) KR20180123542A (es)
CN (1) CN108883309B (es)
AU (1) AU2017234199A1 (es)
BR (1) BR112018068593A2 (es)
CA (1) CA3013673A1 (es)
DK (1) DK3429691T3 (es)
ES (1) ES2848199T3 (es)
GB (1) GB201604484D0 (es)
MX (1) MX2018011249A (es)
WO (1) WO2017157997A1 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170258816A1 (en) 2014-09-12 2017-09-14 Antibiotx Aps Antibacterial Use of Halogenated Salicylanilides
GB201509326D0 (en) 2015-05-29 2015-07-15 Antibio Tx Aps Novel use
GB201615693D0 (en) 2016-09-15 2016-11-02 Combinatorx Infection Ltd Combinations
GB201713653D0 (en) * 2017-08-24 2017-10-11 Antibiotx As Dosage regimen
GB201813876D0 (en) 2018-08-24 2018-10-10 Antibiotx As Treatment
WO2020089467A1 (en) * 2018-11-02 2020-05-07 UNION therapeutics A/S Dosage regimen
CA3118172A1 (en) * 2018-11-02 2020-05-07 UNION therapeutics A/S Halogenated salicylanilides for treating the symptoms of dermatitis
CN109331025A (zh) * 2018-11-22 2019-02-15 华中农业大学 羟氯扎胺在制备抗猪链球菌的药物中的应用
US11419834B2 (en) 2019-02-25 2022-08-23 Rhode Island Hospital Methods for treating diseases or infections caused by or associated with H. pylori using a halogenated salicylanilide
EP4125804A1 (en) 2020-04-01 2023-02-08 UNION therapeutics A/S Treatment
US11045434B1 (en) 2020-04-01 2021-06-29 UNION therapeutics A/S Niclosamide formulations for treating disease
JP2023520229A (ja) 2020-04-01 2023-05-16 ユニオン・セラピューティクス・アー／エス 製剤
CN111821260B (zh) * 2020-06-30 2022-04-01 成都中牧生物药业有限公司 用于混悬液药物的生产方法
CN111743860B (zh) * 2020-06-30 2022-04-05 成都中牧生物药业有限公司 一种混悬液药物配方
AU2022217102A1 (en) * 2021-02-04 2023-08-31 Alan Moana Alexander Niclosamide compositions having improved bioavailability
GB202102488D0 (en) 2021-02-22 2021-04-07 Union Therapeutics As Treatment
CN113908121B (zh) * 2021-10-13 2023-03-28 中国农业科学院上海兽医研究所(中国动物卫生与流行病学中心上海分中心) 一种氯硝柳胺注射液及其制备和应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0487973B1 (en) * 1990-11-26 1996-03-27 Bayer Corporation Topical lotion containing Niclosamide
HUP0102782A3 (en) * 1998-06-19 2002-12-28 Smithkline Beecham Corp Salycilanilide as inhibitors of transcription factor nf-kb
GB2386066A (en) * 2002-02-28 2003-09-10 Norbrook Lab Ltd Long-acting parasiticidal composition with improved bioavailability comprising a salicylanilide, a further anti-parasitic compound & a polymeric species
US7666444B2 (en) * 2004-02-02 2010-02-23 Wyeth Antiparasitic composition
JP4920206B2 (ja) * 2005-06-30 2012-04-18 ライオン株式会社 外用剤組成物及び貼付剤、並びに薬物の経皮吸収組成物
GB0525093D0 (en) * 2005-12-09 2006-01-18 Norbrook Lab Ltd Veterinary composition
US20070254036A1 (en) * 2006-04-13 2007-11-01 Besins Healthcare Sa Treatment of menopause associated symptoms
WO2008006848A1 (en) * 2006-07-13 2008-01-17 Galderma Research & Development Composition comprising a retinoid and benzoyl peroxide
GB0711957D0 (en) * 2007-06-21 2007-08-01 Syntopix Ltd Formulations
EP2143421A1 (en) * 2008-07-07 2010-01-13 Almirall Hermal GmbH Topical composition for the treatment of actinic keratosis
GB2456376A (en) * 2008-12-22 2009-07-15 Syntopix Ltd Antibacterial/anti-acne formulations comprising a halogenated salicylanilide in combination with one or more anti-acne agents

Also Published As

Publication number Publication date
BR112018068593A2 (pt) 2019-04-16
EP3429691B1 (en) 2020-11-04
CA3013673A1 (en) 2017-09-21
KR20180123542A (ko) 2018-11-16
WO2017157997A1 (en) 2017-09-21
DK3429691T3 (da) 2021-02-08
GB201604484D0 (en) 2016-04-27
EP3429691A1 (en) 2019-01-23
ES2848199T3 (es) 2021-08-05
CN108883309B (zh) 2021-08-17
JP2019508463A (ja) 2019-03-28
US20190151231A1 (en) 2019-05-23
AU2017234199A1 (en) 2018-08-09
CN108883309A (zh) 2018-11-23

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