EA201490649A1 - Варианты глюкоамилазы и кодирующие их полинуклеотиды - Google Patents
Варианты глюкоамилазы и кодирующие их полинуклеотидыInfo
- Publication number
- EA201490649A1 EA201490649A1 EA201490649A EA201490649A EA201490649A1 EA 201490649 A1 EA201490649 A1 EA 201490649A1 EA 201490649 A EA201490649 A EA 201490649A EA 201490649 A EA201490649 A EA 201490649A EA 201490649 A1 EA201490649 A1 EA 201490649A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- glucoamylase variants
- polynucleotide code
- variants
- relates
- present
- Prior art date
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
- C12N9/2411—Amylases
- C12N9/2428—Glucan 1,4-alpha-glucosidase (3.2.1.3), i.e. glucoamylase
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
- C12N9/2411—Amylases
- C12N9/2414—Alpha-amylase (3.2.1.1.)
- C12N9/2417—Alpha-amylase (3.2.1.1.) from microbiological source
- C12N9/242—Fungal source
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/20—Aspartic acid; Asparagine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/20—Preparation of compounds containing saccharide radicals produced by the action of an exo-1,4 alpha-glucosidase, e.g. dextrose
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P37/00—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/002—Preparation of hydrocarbons or halogenated hydrocarbons cyclic
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/02—Preparation of hydrocarbons or halogenated hydrocarbons acyclic
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/06—Ethanol, i.e. non-beverage
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/44—Polycarboxylic acids
- C12P7/46—Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/44—Polycarboxylic acids
- C12P7/48—Tricarboxylic acids, e.g. citric acid
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/54—Acetic acid
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/56—Lactic acid
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01001—Alpha-amylase (3.2.1.1)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01003—Glucan 1,4-alpha-glucosidase (3.2.1.3), i.e. glucoamylase
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Mycology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
Настоящее изобретение относится к вариантам глюкоамилазы, характеризующихся улучшенной термостабильностью. Настоящее изобретение также относится к полинуклеотидам, кодирующим варианты; конструктам нуклеиновой кислоты, векторам и клеткам-хозяевам, содержащим полинуклеотиды; и к способам применения вариантов.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161545628P | 2011-10-11 | 2011-10-11 | |
PCT/EP2012/070127 WO2013053801A1 (en) | 2011-10-11 | 2012-10-11 | Glucoamylase variants and polynucleotides encoding same |
Publications (1)
Publication Number | Publication Date |
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EA201490649A1 true EA201490649A1 (ru) | 2014-07-30 |
Family
ID=47049149
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201490649A EA201490649A1 (ru) | 2011-10-11 | 2012-10-11 | Варианты глюкоамилазы и кодирующие их полинуклеотиды |
Country Status (10)
Country | Link |
---|---|
US (7) | US9353362B2 (ru) |
EP (1) | EP2766476B1 (ru) |
CN (1) | CN103946378B (ru) |
CA (1) | CA2853000C (ru) |
DK (1) | DK2766476T3 (ru) |
EA (1) | EA201490649A1 (ru) |
ES (1) | ES2638669T3 (ru) |
IN (1) | IN2014CN03468A (ru) |
MX (1) | MX351762B (ru) |
WO (1) | WO2013053801A1 (ru) |
Families Citing this family (46)
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JP5568307B2 (ja) * | 2006-10-10 | 2014-08-06 | ダニスコ・ユーエス・インク、ジェネンコー・ディビジョン | 修飾された性質を有するグルコアミラーゼ変異体 |
CA2903934A1 (en) * | 2013-03-07 | 2014-09-12 | Novozymes A/S | Glucoamylase variants and polynucleotides encoding same |
CA2915063C (en) | 2013-06-24 | 2023-08-15 | Novozymes A/S | Process of extracting oil from thin stillage |
WO2015007639A1 (en) | 2013-07-17 | 2015-01-22 | Novozymes A/S | Pullulanase chimeras and polynucleotides encoding same |
EP3063282B1 (en) | 2013-09-11 | 2020-03-25 | Novozymes A/S | Processes for producing fermentation products |
HUE056192T2 (hu) | 2014-01-22 | 2022-01-28 | Novozymes As | Pullulanázvariánsok és azokat kódoló polinukleotidok |
EP3209788B1 (en) * | 2014-10-23 | 2019-06-05 | Novozymes A/S | Glucoamylase variants and polynucleotides encoding same |
CN104480127B (zh) * | 2014-12-14 | 2017-04-05 | 长春中医药大学 | 超嗜热糖苷酶突变体及其在人参皂苷ck制备中的应用 |
WO2016196202A1 (en) | 2015-05-29 | 2016-12-08 | Novozymes A/S | Polypeptides having protease activity and polynucleotides encoding same |
WO2016205127A1 (en) | 2015-06-18 | 2016-12-22 | Novozymes A/S | Polypeptides having trehalase activity and the use thereof in process of producing fermentation products |
US20180208916A1 (en) | 2015-07-23 | 2018-07-26 | Novozymes A/S | Alpha-amylase variants and polynucleotides encoding same |
CA2999534A1 (en) | 2015-10-14 | 2017-04-20 | Novozymes A/S | Glucoamylase variants and polynucleotides encoding same |
EP3394275A1 (en) | 2015-12-22 | 2018-10-31 | Novozymes A/S | Process of extracting oil from thin stillage |
WO2018098381A1 (en) | 2016-11-23 | 2018-05-31 | Novozymes A/S | Improved yeast for ethanol production |
CN110072997A (zh) | 2016-11-23 | 2019-07-30 | 诺维信公司 | 具有蛋白酶活性的多肽和编码其的多核苷酸 |
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EP4015524A1 (en) | 2017-06-28 | 2022-06-22 | Novozymes A/S | Polypeptides having trehalase activity and polynucleotides encoding same |
CN111094562A (zh) | 2017-08-08 | 2020-05-01 | 诺维信公司 | 具有海藻糖酶活性的多肽及其在产生发酵产物的方法中的用途 |
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BR112020006356A2 (pt) | 2017-10-04 | 2020-09-29 | Novozymes A/S | polipeptídeo com atividade de protease, polinucleotídeo, construto de ácido nucleico, ou vetor de expressão recombinante, célula hospedeira recombinante, método para a produção de um polipeptídeo com atividade de protease, processos para liquefazer material contendo amido, para produzir produtos de fermentação a partir de material contendo amido e para recuperação de óleo de uma produção de produto de fermentação, composição enzimática, e, uso de uma protease s8a de palaeococcus ferrophilus. |
EP3701037A1 (en) | 2017-10-23 | 2020-09-02 | Novozymes A/S | Processes for reducing lactic acid in a biofuel fermentation system |
CN107828855B (zh) * | 2017-10-31 | 2020-08-21 | 南京欣迪生物药业工程有限责任公司 | 一种精浆中性α-葡糖苷酶检测试剂盒及其应用 |
CA3081096A1 (en) | 2017-12-08 | 2019-06-13 | Novozymes A/S | Alpha-amylase variants and polynucleotides encoding same |
ES2955269T3 (es) | 2017-12-08 | 2023-11-29 | Novozymes As | Variantes de alfa-amilasa y polinucleótidos que codifican las mismas |
CN113286871A (zh) | 2018-01-29 | 2021-08-20 | 诺维信公司 | 用于乙醇生产的氮利用提高的微生物 |
CA3107124A1 (en) | 2018-02-15 | 2019-08-22 | Novozymes A/S | Improved yeast for ethanol production |
WO2019197318A1 (en) | 2018-04-09 | 2019-10-17 | Novozymes A/S | Polypeptides having alpha-amylase activity and polynucleotides encoding same |
BR112020024347A2 (pt) | 2018-05-31 | 2021-02-23 | Novozymes A/S | processos para aumentar o crescimento e a produtividade de levedura |
BR112021000369A2 (pt) | 2018-07-11 | 2021-04-13 | Novozymes A/S | Processos para produção de produtos de fermentação |
CN112601818A (zh) * | 2018-07-25 | 2021-04-02 | 诺维信公司 | 用于生产乙醇的表达酶的酵母 |
US11807889B2 (en) | 2018-10-08 | 2023-11-07 | Novozymes A/S | Yeast expressing a heterologous phospholipase for ethanol production |
BR112021014873A2 (pt) | 2019-01-31 | 2021-10-05 | Novozymes A/S | Polipeptídeo, combinação de enzimas, polinucleotídeo, construto de ácido nucleico ou vetor de expressão recombinante, célula hospedeira recombinante, método de produção de um polipeptídeo, e, processo de produção de um produto de fermentação |
BR112021017085A2 (pt) | 2019-04-02 | 2022-02-08 | Novozymes As | Processo de produção de um produto de fermentação |
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CA3144423A1 (en) | 2019-08-05 | 2021-02-11 | Kurt Creamer | Enzyme blends and processes for producing a high protein feed ingredient from a whole stillage byproduct |
BR112021026477A2 (pt) | 2019-08-06 | 2022-02-08 | Novozymes As | Célula hospedeira recombinante, métodos de produção de um produto de fermentação a partir de um material contendo amido ou contendo celulose, de produção do polipeptídeo maduro, de produção de um derivado de uma célula hospedeira recombinante e de produção de etanol, construto de ácido nucleico ou vetor de expressão, composição, e, uso de uma célula hospedeira recombinante |
AU2020402990A1 (en) | 2019-12-10 | 2022-06-09 | Novozymes A/S | Microorganism for improved pentose fermentation |
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EP4103703A2 (en) | 2020-02-10 | 2022-12-21 | Novozymes A/S | Alpha-amylase variants and polynucleotides encoding same |
US20230399632A1 (en) * | 2020-11-02 | 2023-12-14 | Novozymes A/S | Glucoamylase Variants and Polynucleotides Encoding Same |
CN112359027B (zh) * | 2021-01-13 | 2021-04-13 | 凯莱英生命科学技术(天津)有限公司 | 细胞色素p450酶突变体及其应用 |
CN115386506A (zh) * | 2021-04-16 | 2022-11-25 | 中国科学院亚热带农业生态研究所 | 促进畜禽粪便和秸秆快速堆肥的微生物复合菌剂及其生产生物有机肥的方法 |
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CN113881654B (zh) * | 2021-09-08 | 2023-06-09 | 暨南大学 | 一种对胃蛋白酶抗性提高的α-淀粉酶 |
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DK2316929T3 (en) | 1998-02-27 | 2016-07-25 | Novozymes As | Maltogenic alpha-amylase variants |
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US6352851B1 (en) * | 1998-07-15 | 2002-03-05 | Novozymes A/S | Glucoamylase variants |
DE69932345T2 (de) | 1998-10-26 | 2007-07-19 | Novozymes A/S | Erstellung und durchmusterung von interessierenden dna-banken in zellen von filamentösen pilzen |
CN1329665A (zh) | 1998-12-07 | 2002-01-02 | 诺维信公司 | 具有n末端延伸的葡糖淀粉酶 |
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WO2003048353A1 (en) | 2001-12-07 | 2003-06-12 | Novozymes A/S | Polypeptides having protease activity and nucleic acids encoding same |
DE602004024964D1 (de) | 2003-03-10 | 2010-02-25 | Novozymes As | Verfahren zur herstellung von alkohol |
DK2336308T3 (da) | 2003-06-25 | 2014-11-10 | Novozymes As | Enzymer til forarbejdning af stivelse |
WO2005003311A2 (en) | 2003-06-25 | 2005-01-13 | Novozymes A/S | Enzymes for starch processing |
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JP5452869B2 (ja) | 2004-12-22 | 2014-03-26 | ノボザイムス アクティーゼルスカブ | デンプン加工法 |
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MX338068B (es) | 2010-04-14 | 2016-04-01 | Novozymes As | Polipeptidos que tienen actividad de glucoamilasa y polinucleotidos que codifican los mismos. |
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2012
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- 2012-10-11 DK DK12775472.9T patent/DK2766476T3/en active
- 2012-10-11 US US14/351,469 patent/US9353362B2/en active Active
- 2012-10-11 WO PCT/EP2012/070127 patent/WO2013053801A1/en active Application Filing
- 2012-10-11 EA EA201490649A patent/EA201490649A1/ru unknown
- 2012-10-11 ES ES12775472.9T patent/ES2638669T3/es active Active
- 2012-10-11 CN CN201280050093.8A patent/CN103946378B/zh active Active
- 2012-10-11 CA CA2853000A patent/CA2853000C/en active Active
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- 2012-10-11 IN IN3468CHN2014 patent/IN2014CN03468A/en unknown
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2016
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2017
- 2017-08-15 US US15/677,604 patent/US10113158B2/en active Active
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EP2766476B1 (en) | 2017-05-31 |
US9353362B2 (en) | 2016-05-31 |
CA2853000C (en) | 2022-03-15 |
EP2766476A1 (en) | 2014-08-20 |
IN2014CN03468A (ru) | 2015-07-03 |
US20140255997A1 (en) | 2014-09-11 |
MX351762B (es) | 2017-10-26 |
CN103946378B (zh) | 2018-04-24 |
CA2853000A1 (en) | 2013-04-18 |
US20190002856A1 (en) | 2019-01-03 |
WO2013053801A1 (en) | 2013-04-18 |
US11840713B2 (en) | 2023-12-12 |
MX2014004292A (es) | 2014-07-24 |
CN103946378A (zh) | 2014-07-23 |
US10865399B2 (en) | 2020-12-15 |
US20210062172A1 (en) | 2021-03-04 |
US10113158B2 (en) | 2018-10-30 |
US20170073655A1 (en) | 2017-03-16 |
US20170342393A1 (en) | 2017-11-30 |
US20240084277A1 (en) | 2024-03-14 |
US9540624B2 (en) | 2017-01-10 |
DK2766476T3 (en) | 2017-08-28 |
US20160230157A1 (en) | 2016-08-11 |
ES2638669T3 (es) | 2017-10-23 |
US9765318B2 (en) | 2017-09-19 |
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