EA201170286A1 - Способ получения липосом и способ растворения холестерина - Google Patents

Способ получения липосом и способ растворения холестерина

Info

Publication number
EA201170286A1
EA201170286A1 EA201170286A EA201170286A EA201170286A1 EA 201170286 A1 EA201170286 A1 EA 201170286A1 EA 201170286 A EA201170286 A EA 201170286A EA 201170286 A EA201170286 A EA 201170286A EA 201170286 A1 EA201170286 A1 EA 201170286A1
Authority
EA
Eurasian Patent Office
Prior art keywords
liposom
cholesterin
dissolution
lipids
obtaining
Prior art date
Application number
EA201170286A
Other languages
English (en)
Inventor
Йоситака Симидзу
Ясухико Мибе
Original Assignee
Байомедкор Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Байомедкор Инк. filed Critical Байомедкор Инк.
Publication of EA201170286A1 publication Critical patent/EA201170286A1/ru

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/04—Making microcapsules or microballoons by physical processes, e.g. drying, spraying
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/14—Liposomes; Vesicles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55—Phosphorus compounds
    • A61K8/553—Phospholipids, e.g. lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63—Steroids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Cosmetics (AREA)

Abstract

Предложены способы получения липосом, включающие первую стадию смешивания одного или нескольких липидов и водного раствора, содержащего смешиваемый с водой органический растворитель; стадию нагревания смеси липидов и водного раствора до температуры, при которой липиды растворяются в органическом растворителе; и после стадии нагревания стадию охлаждения полученной смеси до температуры, при которой образуются липосомы. С помощью этого метода могут быть легко получены липосомы, однородные по диаметру частиц и имеющие высокий коэффициент инкапсуляции.
EA201170286A 2008-12-24 2009-12-24 Способ получения липосом и способ растворения холестерина EA201170286A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2008328724 2008-12-24
PCT/JP2009/071484 WO2010074172A1 (ja) 2008-12-24 2009-12-24 リポソームの製造方法ならびにコレステロール溶解方法

Publications (1)

Publication Number Publication Date
EA201170286A1 true EA201170286A1 (ru) 2011-10-31

Family

ID=42287779

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201170286A EA201170286A1 (ru) 2008-12-24 2009-12-24 Способ получения липосом и способ растворения холестерина

Country Status (9)

Country Link
US (1) US20110250262A1 (ru)
EP (1) EP2368627A4 (ru)
JP (2) JP4857392B2 (ru)
KR (1) KR20110110086A (ru)
CN (1) CN102137713A (ru)
AU (1) AU2009331158A1 (ru)
CA (1) CA2735968A1 (ru)
EA (1) EA201170286A1 (ru)
WO (1) WO2010074172A1 (ru)

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JP5771366B2 (ja) 2009-09-02 2015-08-26 株式会社バイオメッドコア リポソーム製造装置及び方法
JP6062360B2 (ja) * 2011-05-02 2017-01-18 株式会社バイオメッドコア 改良された糖被覆リポソーム組成物
CN102397168B (zh) * 2011-11-23 2013-10-02 苏州瑞纳生化技术有限公司 用于化妆品的带电荷柔性纳米脂质体及其制备方法
ES2923757T3 (es) * 2011-12-16 2022-09-30 Modernatx Inc Composiciones de ARNm modificado
KR102205278B1 (ko) * 2013-03-14 2021-01-22 다이서나 파마수이티컬, 인크. 음이온성 약제를 제형화하는 방법
CN105101938A (zh) * 2013-04-02 2015-11-25 气体产品与化学公司 用于个人护理产品的递送系统的组合物
EP3302435B1 (en) 2015-05-26 2023-03-08 Plumb Pharmaceuticals, Inc. Liposome loading
JP6242422B2 (ja) * 2016-03-25 2017-12-06 新日本製薬株式会社 化粧品原料の製造方法
JP6837234B2 (ja) * 2017-01-13 2021-03-03 国立大学法人東海国立大学機構 脂質二重膜構造体とその製造方法
CN111132753B (zh) * 2017-09-04 2022-05-27 一丸自然美健有限公司 pH敏感性脂质体及其制造方法
JP2022092968A (ja) * 2020-12-11 2022-06-23 株式会社東芝 脂質粒子の製造方法
PL244203B1 (pl) * 2021-07-22 2023-12-18 Syvento Spolka Z Ograniczona Odpowiedzialnoscia Ciekła proliposomowa kompozycja środków ochrony roślin oraz sposób wytwarzania kompozycji

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Also Published As

Publication number Publication date
CN102137713A (zh) 2011-07-27
EP2368627A4 (en) 2015-01-14
JP4857392B2 (ja) 2012-01-18
JPWO2010074172A1 (ja) 2012-06-21
KR20110110086A (ko) 2011-10-06
WO2010074172A1 (ja) 2010-07-01
CA2735968A1 (en) 2010-07-01
AU2009331158A1 (en) 2010-07-01
US20110250262A1 (en) 2011-10-13
JP2011256199A (ja) 2011-12-22
EP2368627A1 (en) 2011-09-28

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