EA201070036A1 - Наноразмерные молочно-кислые бактерии - Google Patents

Наноразмерные молочно-кислые бактерии

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Publication number
EA201070036A1
EA201070036A1 EA201070036A EA201070036A EA201070036A1 EA 201070036 A1 EA201070036 A1 EA 201070036A1 EA 201070036 A EA201070036 A EA 201070036A EA 201070036 A EA201070036 A EA 201070036A EA 201070036 A1 EA201070036 A1 EA 201070036A1
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EA
Eurasian Patent Office
Prior art keywords
acid bacteria
nanosized
cells
lactic acid
particle size
Prior art date
Application number
EA201070036A
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English (en)
Other versions
EA020627B1 (ru
Inventor
Хидео Хасегава
Тацухико Кан
Original Assignee
Синва Фармасьютикал Ко., Лтд.
Био-Лаб Лтд.
Дзе Джапаниз Ассосиэйшн Оф Клиникал Рисерч Он Саплиментс
Космо Фудз Ко., Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Синва Фармасьютикал Ко., Лтд., Био-Лаб Лтд., Дзе Джапаниз Ассосиэйшн Оф Клиникал Рисерч Он Саплиментс, Космо Фудз Ко., Лтд. filed Critical Синва Фармасьютикал Ко., Лтд.
Publication of EA201070036A1 publication Critical patent/EA201070036A1/ru
Publication of EA020627B1 publication Critical patent/EA020627B1/ru

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A23K10/18—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00—Lactic or propionic acid bacteria
    • A23V2400/11—Lactobacillus
    • A23V2400/121—Brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/225—Lactobacillus
    • C12R2001/24—Lactobacillus brevis

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Food Science & Technology (AREA)
  • Nanotechnology (AREA)
  • Immunology (AREA)
  • Animal Husbandry (AREA)
  • Biophysics (AREA)
  • Physiology (AREA)
  • Medical Informatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Birds (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)

Abstract

Клетки молочно-кислых бактерий, полученных посредством регулирования рН среды на стадии культивирования и стадиях обработки до нейтрального диапазона, равного, например, от 5 до 8 или около того, при распределении размеров частиц имеют значение параметра (размер частиц), равное 1,0 мкм или меньше. Клетки наноразмерных молочно-кислых бактерий, имеющих такой небольшой размер частиц, обладают замечательной способностью продуцировать IFN-α, а также превосходны для диспергирования в воде.
EA201070036A 2008-06-26 2008-06-26 Способ получения клеток наноразмерных молочно-кислых бактерий и композиции на их основе EA020627B1 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP2008/061612 WO2009157073A1 (ja) 2008-06-26 2008-06-26 ナノ型乳酸菌

Publications (2)

Publication Number Publication Date
EA201070036A1 true EA201070036A1 (ru) 2010-04-30
EA020627B1 EA020627B1 (ru) 2014-12-30

Family

ID=41444150

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201070036A EA020627B1 (ru) 2008-06-26 2008-06-26 Способ получения клеток наноразмерных молочно-кислых бактерий и композиции на их основе

Country Status (7)

Country Link
US (1) US20110189343A1 (ru)
EP (1) EP2206505B1 (ru)
JP (1) JP5257363B2 (ru)
KR (1) KR101580678B1 (ru)
CN (1) CN101686998A (ru)
EA (1) EA020627B1 (ru)
WO (1) WO2009157073A1 (ru)

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US20110189343A1 (en) * 2008-06-26 2011-08-04 Hideo Hasegawa Nano-sized lactic acid bacteria
JP2012136450A (ja) * 2010-12-24 2012-07-19 Nitto Yakuhin Kogyo Kk インフルエンザウイルス感染予防用組成物
JP5950827B2 (ja) 2010-12-28 2016-07-13 キリンホールディングス株式会社 乳酸菌を含むインターフェロン産生誘導剤
WO2012168468A1 (de) * 2011-06-08 2012-12-13 Organobalance Gmbh Sprühgetrocknete lactobacillus stämme / zellen und deren verwendung gegen helicobacter pylori
JP6351985B2 (ja) * 2013-01-30 2018-07-04 株式会社 ソーシン 口腔用組成物
KR101638984B1 (ko) * 2013-05-29 2016-07-13 바이오제닉스코리아 주식회사 나노형 김치 유산균
JP6325828B2 (ja) * 2014-02-04 2018-05-16 小林　孝 微粒子化した乳酸菌（ラクトコッカス・ラクティス・サブスピーシーズ クレモリスＨ−６１株（ＮＩＴＥ ＢＰ−０１７８７））を有効成分として含有するＴＧＦ−β２抑制剤並びにこれを含有するＴＧＦ−β２低下用薬剤及びＴＧＦ−β２低下用食品
JP6325829B2 (ja) * 2014-02-04 2018-05-16 小林　孝 微粒子化した乳酸菌（ラクトコッカス・ラクティス・サブスピーシーズクレモリスｈ−６１株）を有効成分として含有する降圧剤並びにこれを含有する高血圧症の改善用薬剤及び高血圧症の改善用食品
JP6463939B2 (ja) * 2014-10-14 2019-02-06 株式会社ブロマ研究所 免疫機能調整口腔剤
US20170333494A1 (en) * 2014-11-10 2017-11-23 Glaxosmithkline Intellectual Property Development Limited Probiotic therapeutic applications
JP2019510036A (ja) 2016-03-31 2019-04-11 ゴジョ・インダストリーズ・インコーポレイテッド プロバイオティクス／プレバイオティクス有効成分を含む清浄剤組成物
US10806769B2 (en) 2016-03-31 2020-10-20 Gojo Industries, Inc. Antimicrobial peptide stimulating cleansing composition
KR101792780B1 (ko) 2016-04-18 2017-11-02 바이오제닉스코리아 주식회사 나노화된 김치 유산균을 이용한 다이어트 건강기능성 식품
AU2017365019A1 (en) 2016-11-23 2019-07-11 Gojo Industries, Inc. Sanitizer composition with probiotic/prebiotic active ingredient
JP6298912B1 (ja) * 2017-04-10 2018-03-20 有限会社バイオ研 乳酸菌の製造方法、及び免疫調節用組成物
JP6377872B1 (ja) * 2018-03-06 2018-08-22 株式会社いわかつ 健康包皮食品
JP7466166B2 (ja) * 2018-08-08 2024-04-12 有限会社バイオ研 乳酸菌含有ウイルス感染防御剤及びその製造方法
JP7263678B2 (ja) * 2018-11-06 2023-04-25 ハウスウェルネスフーズ株式会社 凝集又は沈殿が抑制された乳酸菌含有飲料の製造方法
US20210401914A1 (en) 2019-07-04 2021-12-30 Sosin Co., Ltd. Oral composition for animal and periodontal disease preventive, infection disease preventive, and mouth odor preventive using the oral composition
CN112931317B (zh) * 2021-03-23 2022-04-12 浙江省海洋水产研究所 一种提高刀鲚育苗成活率的方法

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US20110189343A1 (en) * 2008-06-26 2011-08-04 Hideo Hasegawa Nano-sized lactic acid bacteria
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Also Published As

Publication number Publication date
EP2206505A4 (en) 2011-06-22
CN101686998A (zh) 2010-03-31
KR101580678B1 (ko) 2015-12-28
JP5257363B2 (ja) 2013-08-07
KR20110033893A (ko) 2011-04-01
WO2009157073A1 (ja) 2009-12-30
EP2206505B1 (en) 2013-07-31
EA020627B1 (ru) 2014-12-30
US20110189343A1 (en) 2011-08-04
JPWO2009157073A1 (ja) 2011-12-01
EP2206505A1 (en) 2010-07-14

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