EA200971133A1 - Производство фармацевтических композиций с быстрым высвобождением на основе водонерастворимых лекарственных средств и фармацевтические композиции, получаемые способом по изобретению - Google Patents

Производство фармацевтических композиций с быстрым высвобождением на основе водонерастворимых лекарственных средств и фармацевтические композиции, получаемые способом по изобретению

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Publication number
EA200971133A1
EA200971133A1 EA200971133A EA200971133A EA200971133A1 EA 200971133 A1 EA200971133 A1 EA 200971133A1 EA 200971133 A EA200971133 A EA 200971133A EA 200971133 A EA200971133 A EA 200971133A EA 200971133 A1 EA200971133 A1 EA 200971133A1
Authority
EA
Eurasian Patent Office
Prior art keywords
pharmaceutical compositions
based water
quickly frozen
soluble medicines
manufacturing
Prior art date
Application number
EA200971133A
Other languages
English (en)
Inventor
Поул Бертелсен
Original Assignee
Никомед Данмарк Апс
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Никомед Данмарк Апс filed Critical Никомед Данмарк Апс
Publication of EA200971133A1 publication Critical patent/EA200971133A1/ru

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Обнаружено, что фармацевтические композиции, включающие водонерастворимые лекарственные средства, могут быть произведены и составлены способом, обеспечивающим быстрое растворение в желудочной жидкости. Преимущество этого способа производства заключается в том, что он обеспечивает существенно улучшенную стабильность, благодаря чему могут быть получены композиции, имеющие более длительный срок хранения, чем лекарственные средства, составленные и переработанные традиционным способом.
EA200971133A 2004-06-29 2005-06-28 Производство фармацевтических композиций с быстрым высвобождением на основе водонерастворимых лекарственных средств и фармацевтические композиции, получаемые способом по изобретению EA200971133A1 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA200401021 2004-06-29

Publications (1)

Publication Number Publication Date
EA200971133A1 true EA200971133A1 (ru) 2010-10-29

Family

ID=34973654

Family Applications (2)

Application Number Title Priority Date Filing Date
EA200700078A EA014443B1 (ru) 2004-06-29 2005-06-28 Фармацевтическая композиция (варианты) и способ ее производства
EA200971133A EA200971133A1 (ru) 2004-06-29 2005-06-28 Производство фармацевтических композиций с быстрым высвобождением на основе водонерастворимых лекарственных средств и фармацевтические композиции, получаемые способом по изобретению

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EA200700078A EA014443B1 (ru) 2004-06-29 2005-06-28 Фармацевтическая композиция (варианты) и способ ее производства

Country Status (23)

Country Link
US (2) US20070218128A1 (ru)
EP (1) EP1916994B1 (ru)
JP (2) JP5438898B2 (ru)
KR (1) KR100875299B1 (ru)
CN (2) CN1976678B (ru)
AU (1) AU2005256321B2 (ru)
BR (1) BRPI0508063A (ru)
CA (1) CA2572359C (ru)
EA (2) EA014443B1 (ru)
ES (1) ES2450648T3 (ru)
GE (1) GEP20094671B (ru)
IL (1) IL180071A0 (ru)
MA (1) MA28754B1 (ru)
MX (1) MXPA06015131A (ru)
NO (1) NO20065763L (ru)
NZ (1) NZ552208A (ru)
PL (1) PL1916994T3 (ru)
SA (2) SA108290833B1 (ru)
TN (1) TNSN06434A1 (ru)
TW (1) TWI376242B (ru)
UA (1) UA93353C2 (ru)
WO (1) WO2006000228A2 (ru)
ZA (1) ZA200700531B (ru)

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Also Published As

Publication number Publication date
US20130059842A1 (en) 2013-03-07
MXPA06015131A (es) 2007-03-26
CA2572359C (en) 2010-08-03
MA28754B1 (fr) 2007-07-02
TWI376242B (en) 2012-11-11
ZA200700531B (en) 2009-09-30
GEP20094671B (en) 2009-04-27
UA93353C2 (ru) 2011-02-10
WO2006000228A2 (en) 2006-01-05
SA108290833B1 (ar) 2012-03-24
IL180071A0 (en) 2007-05-15
WO2006000228A3 (en) 2006-08-31
NO20065763L (no) 2007-01-29
US20070218128A1 (en) 2007-09-20
AU2005256321B2 (en) 2008-11-20
CN1976678B (zh) 2010-06-02
JP5438898B2 (ja) 2014-03-12
KR20070032035A (ko) 2007-03-20
EP1916994B1 (en) 2013-12-11
KR100875299B1 (ko) 2008-12-23
EP1916994A2 (en) 2008-05-07
PL1916994T3 (pl) 2014-05-30
SA05260191B1 (ar) 2009-09-02
CA2572359A1 (en) 2006-01-05
CN1976678A (zh) 2007-06-06
CN101513391A (zh) 2009-08-26
TNSN06434A1 (en) 2008-02-22
EA014443B1 (ru) 2010-12-30
JP2011213730A (ja) 2011-10-27
JP2008504307A (ja) 2008-02-14
CN101513391B (zh) 2013-03-13
WO2006000228B1 (en) 2006-11-09
EA200700078A1 (ru) 2007-06-29
BRPI0508063A (pt) 2007-07-17
TW200605919A (en) 2006-02-16
AU2005256321A1 (en) 2006-01-05
NZ552208A (en) 2008-11-28
ES2450648T3 (es) 2014-03-25

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