EA200500079A1 - Композиция таблетки прамипексола с замедленным высвобождением - Google Patents

Композиция таблетки прамипексола с замедленным высвобождением

Info

Publication number
EA200500079A1
EA200500079A1 EA200500079A EA200500079A EA200500079A1 EA 200500079 A1 EA200500079 A1 EA 200500079A1 EA 200500079 A EA200500079 A EA 200500079A EA 200500079 A EA200500079 A EA 200500079A EA 200500079 A1 EA200500079 A1 EA 200500079A1
Authority
EA
Eurasian Patent Office
Prior art keywords
tablet
pramipexol
composition
slow delayed
delayed
Prior art date
Application number
EA200500079A
Other languages
English (en)
Other versions
EA009663B1 (ru
Inventor
Грегори Э. Эмидон
Локсидх Д. Ганоркар
Джон М. Хаймлих
Эрнест Дж. Ли
Роберт М. Ноак
Джозеф П. Рео
Конни Дж. Скоуг
Original Assignee
Фармация Корпорейшн
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Фармация Корпорейшн filed Critical Фармация Корпорейшн
Publication of EA200500079A1 publication Critical patent/EA200500079A1/ru
Publication of EA009663B1 publication Critical patent/EA009663B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/428—Thiazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)

Abstract

Предложена фармацевтическая композиция с замедленным высвобождением в форме обеспечивающей пероральную доставку таблетки, содержащей растворимую в воде соль прамипексола, диспергированную в матрице, содержащей гидрофильный полимер и крахмал, имеющий предел прочности на разрыв по меньшей мере примерно 0,15 кН/смпри относительном содержании твердого вещества, типичном для таблетки.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200500079A 2002-07-25 2003-07-25 Лекарственная форма с замедленным высвобождением, содержащая прамипексол, и способ лечения субъекта EA009663B1 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US39842702P 2002-07-25 2002-07-25
US39844702P 2002-07-25 2002-07-25
US47951303P 2003-06-18 2003-06-18
PCT/US2003/023205 WO2004010997A1 (en) 2002-07-25 2003-07-25 Sustained-release tablet composition of pramipexole

Publications (2)

Publication Number Publication Date
EA200500079A1 true EA200500079A1 (ru) 2005-06-30
EA009663B1 EA009663B1 (ru) 2008-02-28

Family

ID=31192087

Family Applications (2)

Application Number Title Priority Date Filing Date
EA200500079A EA009663B1 (ru) 2002-07-25 2003-07-25 Лекарственная форма с замедленным высвобождением, содержащая прамипексол, и способ лечения субъекта
EA200702187A EA200702187A1 (ru) 2002-07-25 2003-07-25 Композиция таблетки прамипексола с замедленным высвобождением

Family Applications After (1)

Application Number Title Priority Date Filing Date
EA200702187A EA200702187A1 (ru) 2002-07-25 2003-07-25 Композиция таблетки прамипексола с замедленным высвобождением

Country Status (41)

Country Link
US (2) US20050226926A1 (ru)
EP (2) EP1987832A1 (ru)
JP (1) JP4700963B2 (ru)
KR (1) KR100712832B1 (ru)
CN (1) CN1313092C (ru)
AP (1) AP2201A (ru)
AR (1) AR040681A1 (ru)
AT (1) ATE406162T1 (ru)
AU (1) AU2003261241B2 (ru)
BR (1) BR0312960A (ru)
CA (1) CA2492854C (ru)
CR (1) CR7661A (ru)
CU (1) CU23440B7 (ru)
CY (1) CY1110408T1 (ru)
DE (1) DE60323235D1 (ru)
DK (1) DK1531814T3 (ru)
EA (2) EA009663B1 (ru)
EC (1) ECSP055568A (ru)
ES (1) ES2310673T3 (ru)
GE (1) GEP20074048B (ru)
HK (1) HK10777456A1 (ru)
HR (1) HRP20041235B1 (ru)
IL (1) IL166078A0 (ru)
IS (1) IS7623A (ru)
MA (1) MA27328A1 (ru)
ME (1) MEP52308A (ru)
MX (1) MXPA05001054A (ru)
MY (1) MY138846A (ru)
NO (1) NO334298B1 (ru)
NZ (1) NZ537790A (ru)
OA (1) OA13303A (ru)
PA (1) PA8578301A1 (ru)
PE (1) PE20040130A1 (ru)
PL (1) PL215587B1 (ru)
PT (1) PT1531814E (ru)
RS (1) RS51719B (ru)
SI (1) SI1531814T1 (ru)
TW (1) TWI347849B (ru)
UY (1) UY27912A1 (ru)
WO (1) WO2004010997A1 (ru)
ZA (1) ZA200500439B (ru)

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