EA200401621A1 - Модуляторы сск-1 рецепторов - Google Patents
Модуляторы сск-1 рецепторовInfo
- Publication number
- EA200401621A1 EA200401621A1 EA200401621A EA200401621A EA200401621A1 EA 200401621 A1 EA200401621 A1 EA 200401621A1 EA 200401621 A EA200401621 A EA 200401621A EA 200401621 A EA200401621 A EA 200401621A EA 200401621 A1 EA200401621 A1 EA 200401621A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- cck
- modulators
- receptors
- pyrazoles
- proposed
- Prior art date
Links
- 150000003217 pyrazoles Chemical class 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Diabetes (AREA)
- Addiction (AREA)
- Child & Adolescent Psychology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Nutrition Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pyridine Compounds (AREA)
Abstract
В настоящем изобретении предложены некоторые модуляторы ССК-1 рецепторов на основе пиразолов.Международная заявка была опубликована вместе с отчетом о международном поиске.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US39349302P | 2002-07-03 | 2002-07-03 | |
PCT/US2003/020787 WO2004007463A1 (en) | 2002-07-03 | 2003-07-02 | Cck-1 receptor modulators |
Publications (2)
Publication Number | Publication Date |
---|---|
EA200401621A1 true EA200401621A1 (ru) | 2005-06-30 |
EA009479B1 EA009479B1 (ru) | 2008-02-28 |
Family
ID=30115589
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA200401621A EA009479B1 (ru) | 2002-07-03 | 2003-07-02 | Модуляторы сск-1 рецепторов |
Country Status (22)
Country | Link |
---|---|
US (2) | US7037931B2 (ru) |
EP (1) | EP1525190A1 (ru) |
JP (1) | JP2006501194A (ru) |
KR (1) | KR20050042130A (ru) |
CN (1) | CN100522947C (ru) |
AR (1) | AR041183A1 (ru) |
AU (1) | AU2003253776A1 (ru) |
BR (1) | BR0312378A (ru) |
CA (1) | CA2491213A1 (ru) |
CL (1) | CL2003001360A1 (ru) |
CO (1) | CO5400148A1 (ru) |
EA (1) | EA009479B1 (ru) |
HR (1) | HRP20041224A2 (ru) |
IL (1) | IL166069A0 (ru) |
MX (1) | MXPA05000204A (ru) |
NO (1) | NO20050498L (ru) |
NZ (1) | NZ537899A (ru) |
PL (1) | PL374757A1 (ru) |
TW (1) | TW200418469A (ru) |
UA (1) | UA79804C2 (ru) |
WO (1) | WO2004007463A1 (ru) |
ZA (1) | ZA200500973B (ru) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UA79804C2 (en) * | 2002-07-03 | 2007-07-25 | Janssen Pharmaceutica Nv | Cck-1 receptor modulators |
JP2006523719A (ja) | 2003-04-18 | 2006-10-19 | メモリー・ファーマシューティカルズ・コーポレイション | ホスホジエステラーゼ4抑制剤としてのピラゾール誘導体 |
BRPI0412269A (pt) * | 2003-07-02 | 2006-09-05 | Janssen Pharmaceutica Nv | moduladores de receptor de cck-1 |
US20050020565A1 (en) * | 2003-07-02 | 2005-01-27 | Jones Todd K. | CCK-1 receptor modulators |
US7250434B2 (en) | 2003-12-22 | 2007-07-31 | Janssen Pharmaceutica N.V. | CCK-1 receptor modulators |
WO2006004742A2 (en) * | 2004-06-30 | 2006-01-12 | Janssen Pharamceutica N.V. | α, β-UNSATURATED ESTERS AND ACIDS BY STEREOSELECTIVE DEHYDRATION |
AU2005295753A1 (en) | 2004-10-15 | 2006-04-27 | Memory Pharmaceuticals Corporation | Pyrazole derivatives as phosphodiesterase 4 inhibitors |
US20060177438A1 (en) * | 2005-02-08 | 2006-08-10 | New England Medical Center | Methods of altering absorption of hydrophobic compounds |
ATE479435T1 (de) * | 2006-04-14 | 2010-09-15 | Merck Sharp & Dohme | Substituierte imidazol-4-carboxamide als cholecystokinin-1-rezeptor-modulatoren |
US7759352B2 (en) | 2006-04-14 | 2010-07-20 | Merck Sharp & Dohme Corp. | Substituted imidazole-4-carboxamides as cholecystokinin-1 receptor modulators |
EP2642856B1 (en) * | 2010-11-24 | 2017-07-19 | The Ohio State University Research Foundation | Integrin-linked kinase inhibitors |
WO2015077572A1 (en) | 2013-11-22 | 2015-05-28 | CL BioSciences LLC | Gastrin antagonists (eg yf476, netazepide) for treatment and prevention of osteoporosis |
CN105722834B (zh) | 2013-12-13 | 2017-12-22 | 豪夫迈·罗氏有限公司 | 酪氨酸蛋白激酶抑制剂 |
CN105793252B (zh) | 2013-12-13 | 2018-01-30 | 豪夫迈·罗氏有限公司 | 布鲁顿氏酪氨酸激酶抑制剂 |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5164381A (en) | 1986-05-29 | 1992-11-17 | Ortho Pharmaceutical Corporation | Pharmacologically active 1,5-diaryl-3-substituted pyrazoles and method for synthesizing the same |
US4826868A (en) | 1986-05-29 | 1989-05-02 | Ortho Pharmaceutical Corporation | 1,5-Diaryl-3-substituted pyrazoles pharmaceutical compositions and use |
AU611437B2 (en) | 1987-05-29 | 1991-06-13 | Ortho Pharmaceutical Corporation | Pharmacologically active 2- and 3-substituted (1',5'-diaryl-3-pyrazolyl)-n-hydroxypropanamides and method for synthesizing the same |
US5051518A (en) | 1987-05-29 | 1991-09-24 | Ortho Pharmaceutical Corporation | Pharmacologically active 2- and 3-substituted (1',5'-diaryl-3-pyrazolyl)-N-hydroxypropanamides |
IL98785A (en) * | 1990-07-17 | 1995-11-27 | Lilly Co Eli | Pyrazolidinones and derivatives of pyrazoline-3 competitors of KCC and gastrin and pharmaceutical preparations containing them |
PT720601E (pt) * | 1993-08-10 | 2001-02-28 | Black James Foundation | Ligandos de receptores de gastrina e cck |
US5756529A (en) | 1995-09-29 | 1998-05-26 | G.D. Searle & Co. | Substituted pyrazolyl benzenesulfonamides for use in veterinary therapies |
JPH09151183A (ja) * | 1995-12-01 | 1997-06-10 | Yoshitomi Pharmaceut Ind Ltd | チエニルアミド化合物 |
DE19621687A1 (de) | 1996-05-30 | 1997-12-04 | Bayer Ag | Verfahren zur Herstellung von substituierten Arylpyrazolen |
ATE266022T1 (de) | 2000-03-06 | 2004-05-15 | Smithkline Beecham Plc | Imidazol derivate als raf kinase inhibitoren |
GB0011089D0 (en) | 2000-05-08 | 2000-06-28 | Black James Foundation | Gastrin and cholecystokinin receptor ligands (11) |
GB0011092D0 (en) | 2000-05-08 | 2000-06-28 | Black James Foundation | Gastrin and cholecystokinin receptor ligands (III) |
GB0011095D0 (en) | 2000-05-08 | 2000-06-28 | Black James Foundation | astrin and cholecystokinin receptor ligands (III) |
GB0016787D0 (en) * | 2000-07-07 | 2000-08-30 | Pfizer Ltd | Compounds useful in therapy |
ES2337127T3 (es) * | 2000-11-02 | 2010-04-21 | Ajinomoto Co., Inc. | Nuevos derivados de pirazol y remedios contra la diabetes que los contienen. |
US6784185B2 (en) * | 2001-03-16 | 2004-08-31 | Pfizer Inc. | Pharmaceutically active compounds |
CA2445003A1 (en) * | 2001-05-16 | 2002-11-21 | Boehringer Ingelheim Pharmaceuticals, Inc. | Diarylurea derivatives useful as anti-inflammatory agents |
JP4342939B2 (ja) * | 2001-08-03 | 2009-10-14 | バーテックス ファーマシューティカルズ インコーポレイテッド | ピラゾール誘導キナーゼインヒビターおよびその使用 |
MXPA04001087A (es) * | 2001-08-03 | 2004-07-08 | Vertex Pharma | Derivados de pirazol como inhibidores de cinasa y uso de los mismos. |
JP2005508320A (ja) | 2001-09-18 | 2005-03-31 | オンコノバ・セラピューティックス・インコーポレーテッド | 1,5−ジアリール−3−置換ピラゾールの調製方法 |
BR0212661A (pt) * | 2001-09-19 | 2004-08-24 | Pharmacia Corp | Compostos de pirazolil benzenossulfamida substituìdos para o tratamento de inflamação |
WO2003037336A1 (en) * | 2001-11-02 | 2003-05-08 | Pfizer Products Inc. | 1-(5-sulfonyl-pyridin-2-yl)-5-(methylidene-cycloalkylmethoxy)-1h-pyrazole-4-carbonitrile derivatives and other compounds as cyclooxygenase inhibitors for the treatment of arthritis, neurodegeneration and colon cancer |
WO2004000788A1 (en) * | 2002-06-19 | 2003-12-31 | Bristol-Myers Squibb Company | Ureido-substituted aniline compounds useful as serine protease inhibitors |
UA79804C2 (en) * | 2002-07-03 | 2007-07-25 | Janssen Pharmaceutica Nv | Cck-1 receptor modulators |
-
2003
- 2003-02-07 UA UAA200500955A patent/UA79804C2/uk unknown
- 2003-07-02 EA EA200401621A patent/EA009479B1/ru not_active IP Right Cessation
- 2003-07-02 AU AU2003253776A patent/AU2003253776A1/en not_active Abandoned
- 2003-07-02 BR BR0312378-2A patent/BR0312378A/pt not_active IP Right Cessation
- 2003-07-02 CN CNB038207613A patent/CN100522947C/zh not_active Expired - Fee Related
- 2003-07-02 JP JP2004521518A patent/JP2006501194A/ja active Pending
- 2003-07-02 PL PL03374757A patent/PL374757A1/xx not_active Application Discontinuation
- 2003-07-02 MX MXPA05000204A patent/MXPA05000204A/es active IP Right Grant
- 2003-07-02 CA CA002491213A patent/CA2491213A1/en not_active Abandoned
- 2003-07-02 EP EP03764341A patent/EP1525190A1/en not_active Withdrawn
- 2003-07-02 US US10/612,150 patent/US7037931B2/en not_active Expired - Lifetime
- 2003-07-02 KR KR1020057000056A patent/KR20050042130A/ko not_active Application Discontinuation
- 2003-07-02 WO PCT/US2003/020787 patent/WO2004007463A1/en active Application Filing
- 2003-07-02 NZ NZ537899A patent/NZ537899A/en unknown
- 2003-07-03 CO CO03056084A patent/CO5400148A1/es not_active Application Discontinuation
- 2003-07-03 CL CL200301360A patent/CL2003001360A1/es unknown
- 2003-07-03 TW TW092118137A patent/TW200418469A/zh unknown
- 2003-07-03 AR ARP030102418A patent/AR041183A1/es unknown
-
2004
- 2004-12-29 HR HR20041224A patent/HRP20041224A2/xx not_active Application Discontinuation
- 2004-12-30 IL IL16606904A patent/IL166069A0/xx unknown
-
2005
- 2005-01-28 NO NO20050498A patent/NO20050498L/no not_active Application Discontinuation
- 2005-02-02 ZA ZA200500973A patent/ZA200500973B/en unknown
- 2005-09-19 US US11/230,200 patent/US7465808B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
NZ537899A (en) | 2007-04-27 |
UA79804C2 (en) | 2007-07-25 |
HRP20041224A2 (en) | 2007-03-31 |
US20060014817A1 (en) | 2006-01-19 |
MXPA05000204A (es) | 2005-09-30 |
CA2491213A1 (en) | 2004-01-22 |
WO2004007463A1 (en) | 2004-01-22 |
CN1678587A (zh) | 2005-10-05 |
BR0312378A (pt) | 2005-04-26 |
TW200418469A (en) | 2004-10-01 |
US20040067983A1 (en) | 2004-04-08 |
IL166069A0 (en) | 2006-01-15 |
KR20050042130A (ko) | 2005-05-04 |
CN100522947C (zh) | 2009-08-05 |
CO5400148A1 (es) | 2004-05-31 |
CL2003001360A1 (es) | 2005-06-03 |
AR041183A1 (es) | 2005-05-04 |
US7037931B2 (en) | 2006-05-02 |
AU2003253776A1 (en) | 2004-02-02 |
ZA200500973B (en) | 2006-04-26 |
NO20050498L (no) | 2005-03-16 |
US7465808B2 (en) | 2008-12-16 |
PL374757A1 (en) | 2005-10-31 |
EP1525190A1 (en) | 2005-04-27 |
JP2006501194A (ja) | 2006-01-12 |
EA009479B1 (ru) | 2008-02-28 |
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