ATE479435T1 - Substituierte imidazol-4-carboxamide als cholecystokinin-1-rezeptor-modulatoren - Google Patents
Substituierte imidazol-4-carboxamide als cholecystokinin-1-rezeptor-modulatorenInfo
- Publication number
- ATE479435T1 ATE479435T1 AT07755237T AT07755237T ATE479435T1 AT E479435 T1 ATE479435 T1 AT E479435T1 AT 07755237 T AT07755237 T AT 07755237T AT 07755237 T AT07755237 T AT 07755237T AT E479435 T1 ATE479435 T1 AT E479435T1
- Authority
- AT
- Austria
- Prior art keywords
- cholecystokinin
- substituted imidazole
- carboxamide
- receptor modulators
- receptor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Luminescent Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79196206P | 2006-04-14 | 2006-04-14 | |
| PCT/US2007/008901 WO2007120688A2 (en) | 2006-04-14 | 2007-04-10 | Substituted imidazole 4-carboxamides as cholecystokinin-1 receptor modulators |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE479435T1 true ATE479435T1 (de) | 2010-09-15 |
Family
ID=38610143
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07755237T ATE479435T1 (de) | 2006-04-14 | 2007-04-10 | Substituierte imidazol-4-carboxamide als cholecystokinin-1-rezeptor-modulatoren |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7858629B2 (de) |
| EP (1) | EP2010178B1 (de) |
| JP (1) | JP2009533445A (de) |
| AT (1) | ATE479435T1 (de) |
| AU (1) | AU2007238804A1 (de) |
| CA (1) | CA2649927A1 (de) |
| DE (1) | DE602007008868D1 (de) |
| WO (1) | WO2007120688A2 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2008013237A (es) | 2006-04-14 | 2009-03-06 | Merck & Co Inc | Imidazol 4-caroxamidas sustituidas como moduladores del receptor colecistoquinina-1. |
| US7759352B2 (en) | 2006-04-14 | 2010-07-20 | Merck Sharp & Dohme Corp. | Substituted imidazole-4-carboxamides as cholecystokinin-1 receptor modulators |
| EP2044055A4 (de) * | 2006-07-21 | 2011-03-23 | Takeda Pharmaceutical | Amidverbindungen |
| WO2010067233A1 (en) | 2008-12-08 | 2010-06-17 | Pfizer Inc. | 1,2,4 triazolo [4, 3 -a] [1,5] benzodiazepin-5 (6h) -ones as agonists of the cholecystokinin-1 receptor (cck-ir) |
| EP2683699B1 (de) | 2011-03-08 | 2015-06-24 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| US8871758B2 (en) | 2011-03-08 | 2014-10-28 | Sanofi | Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof |
| US8828995B2 (en) | 2011-03-08 | 2014-09-09 | Sanofi | Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
| WO2012120052A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
| WO2012120054A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| EP2567959B1 (de) | 2011-09-12 | 2014-04-16 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridin-4-carbonsäureamid-derivate als kinaseinhibitoren |
| BR112022006546A2 (pt) | 2019-10-07 | 2022-08-30 | Kallyope Inc | Agonistas de gpr119 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2133355A1 (en) | 1993-10-04 | 1995-04-05 | Itaru Nitta | Method for producing polypeptide |
| GB0011089D0 (en) * | 2000-05-08 | 2000-06-28 | Black James Foundation | Gastrin and cholecystokinin receptor ligands (11) |
| WO2002055495A1 (en) | 2001-01-15 | 2002-07-18 | Glaxo Group Limited | Aryl piperidine derivatives as inducers of ldl-receptor expression |
| AU2002319627A1 (en) | 2001-07-20 | 2003-03-03 | Merck And Co., Inc. | Substituted imidazoles as cannabinoid receptor modulators |
| US7109216B2 (en) | 2001-09-21 | 2006-09-19 | Solvay Pharmaceuticals B.V. | 1H-imidazole derivatives having CB1 agonistic, CB1 partial agonistic or CB1-antagonistic activity |
| GT200200188A (es) | 2001-09-24 | 2003-06-25 | Preparacion y uso de derivados de imidazol para el tratamiento de la obesidad | |
| US20040248956A1 (en) | 2002-01-29 | 2004-12-09 | Hagmann William K | Substituted imidazoles as cannabinoid receptor modulators |
| UA79804C2 (en) | 2002-07-03 | 2007-07-25 | Janssen Pharmaceutica Nv | Cck-1 receptor modulators |
| US20060189591A1 (en) | 2003-04-21 | 2006-08-24 | Daiichi Pharmaceutical Co., Ltd. | Five-membered heterocyclic derivative |
| US20050026983A1 (en) | 2003-07-30 | 2005-02-03 | Pfizer Inc | Imidazole compounds and uses thereof |
| AU2004283903B2 (en) | 2003-10-20 | 2010-12-02 | Solvay Pharmaceuticals B.V. | 1H-imidazole derivatives as cannabinoid receptor modulators |
| US20050124660A1 (en) | 2003-10-27 | 2005-06-09 | Jochen Antel | Novel medical uses of compounds showing CB1-antagonistic activity and combination treatment involving said compounds |
| WO2005063716A1 (en) | 2003-12-22 | 2005-07-14 | Janssen Pharmaceutica, N.V. | Imidazoles and their use cck-1 receptor modulators |
| EP1735287A1 (de) | 2004-04-03 | 2006-12-27 | Astrazeneca AB | Therapeutische mittel |
| US7759352B2 (en) | 2006-04-14 | 2010-07-20 | Merck Sharp & Dohme Corp. | Substituted imidazole-4-carboxamides as cholecystokinin-1 receptor modulators |
| MX2008013237A (es) | 2006-04-14 | 2009-03-06 | Merck & Co Inc | Imidazol 4-caroxamidas sustituidas como moduladores del receptor colecistoquinina-1. |
-
2007
- 2007-04-10 DE DE602007008868T patent/DE602007008868D1/de active Active
- 2007-04-10 CA CA002649927A patent/CA2649927A1/en not_active Abandoned
- 2007-04-10 US US12/226,048 patent/US7858629B2/en not_active Expired - Fee Related
- 2007-04-10 AU AU2007238804A patent/AU2007238804A1/en not_active Abandoned
- 2007-04-10 AT AT07755237T patent/ATE479435T1/de not_active IP Right Cessation
- 2007-04-10 EP EP07755237A patent/EP2010178B1/de not_active Not-in-force
- 2007-04-10 JP JP2009505444A patent/JP2009533445A/ja not_active Withdrawn
- 2007-04-10 WO PCT/US2007/008901 patent/WO2007120688A2/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| US7858629B2 (en) | 2010-12-28 |
| CA2649927A1 (en) | 2007-10-25 |
| WO2007120688A2 (en) | 2007-10-25 |
| WO2007120688A3 (en) | 2008-07-17 |
| US20090239862A1 (en) | 2009-09-24 |
| AU2007238804A1 (en) | 2007-10-25 |
| EP2010178B1 (de) | 2010-09-01 |
| DE602007008868D1 (de) | 2010-10-14 |
| EP2010178A2 (de) | 2009-01-07 |
| JP2009533445A (ja) | 2009-09-17 |
| EP2010178A4 (de) | 2009-04-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE515504T1 (de) | Substituierte imidazol-4-carboxamide als cholecystokinin-1-rezeptor-modulatoren | |
| ATE473004T1 (de) | Substituierte imidazol-4-carboxamide als cholecystokinin-1-rezeptor-modulatoren | |
| ATE479435T1 (de) | Substituierte imidazol-4-carboxamide als cholecystokinin-1-rezeptor-modulatoren | |
| WO2008008286A3 (en) | Substituted pyrazoles as ghrelin receptor antagonists | |
| NO20084374L (no) | Imidazoltiazolforbindelser for behandling av sykdom | |
| EP2217596B8 (de) | Bicyclische heterocyclische derivate und ihre verwendung als modulatoren der aktivität von gpr 119 | |
| EA200700262A1 (ru) | Арилидены для лечения заболеваний, опосредуемых эстроген-родственным рецепторам альфа | |
| ATE516300T1 (de) | Neuromedin-u-rezeptoragonisten und ihre verwendung | |
| TW200745126A (en) | Bicyclic heteroaryl derivatives as cannabinoid receptor modulators | |
| EA200800835A1 (ru) | Циклопропиламины в качестве модуляторов рецептора гистамина н | |
| ATE345329T1 (de) | Pyridinderivate als modulatoren des cb2-rezeptors | |
| MY149855A (en) | Benzimidazole derivatives and their use for modulating the gaba? receptor complex | |
| MX2009009415A (es) | Compuestos de tetrahidroisoquinolina como moduladores del receptor h3 de la histamina. | |
| MY146506A (en) | Substituted pyridyl amide compounds as modulators of the histamine h3 receptor | |
| IL193479A0 (en) | Modulators of muscarinic receptors | |
| MX2010006206A (es) | Derivados de oxindol substituidos por 5-halogeno y el uso de los mismos para el tratamiento de enfermedades dependientes de la vasopresina. | |
| DE602007009873D1 (de) | Substituierte diazepin-sulfonamide als bombesin-rezeptor-subtyp-3-modulatoren | |
| MX2009004112A (es) | Imidazoles sustituidos como moduladores del receptor de bombesina subtipo-3. | |
| EA201070637A1 (ru) | Соединения циклоалкилокси- и гетероциклоалкилоксипиридина как модуляторы гистаминового рецептора н | |
| IL189974A0 (en) | Benzimidazole derivatives and their use for modulating the gabaa receptor complex | |
| MX2009013197A (es) | Derivados terapeuticos de pirazolonaftiridina. | |
| MX2009009364A (es) | Compuestos de indol y benzotiofeno como moduladores del receptor de histamina h3. | |
| ATE528006T1 (de) | Substituierte aminopyrimidine als cholecystokinin-1-rezeptormodulatoren | |
| WO2008051404A3 (en) | Substituted imidazoles as bombesin receptor subtype-3 modulators | |
| ATE540953T1 (de) | Bizyklische imidazol- oder thiadiazol- heterozyklen als selektive androgen-rezeptor- modulatoren |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |