ATE473004T1 - Substituierte imidazol-4-carboxamide als cholecystokinin-1-rezeptor-modulatoren - Google Patents
Substituierte imidazol-4-carboxamide als cholecystokinin-1-rezeptor-modulatorenInfo
- Publication number
- ATE473004T1 ATE473004T1 AT07755283T AT07755283T ATE473004T1 AT E473004 T1 ATE473004 T1 AT E473004T1 AT 07755283 T AT07755283 T AT 07755283T AT 07755283 T AT07755283 T AT 07755283T AT E473004 T1 ATE473004 T1 AT E473004T1
- Authority
- AT
- Austria
- Prior art keywords
- cholecystokinin
- substituted imidazole
- carboxamide
- receptor modulators
- receptor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Luminescent Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US79213406P | 2006-04-14 | 2006-04-14 | |
PCT/US2007/008956 WO2007120718A2 (en) | 2006-04-14 | 2007-04-10 | Substituted imidazole 4-carboxamides as cholecystokinin-1 receptor modulators |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE473004T1 true ATE473004T1 (de) | 2010-07-15 |
Family
ID=38610151
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT07755283T ATE473004T1 (de) | 2006-04-14 | 2007-04-10 | Substituierte imidazol-4-carboxamide als cholecystokinin-1-rezeptor-modulatoren |
Country Status (8)
Country | Link |
---|---|
US (1) | US7759352B2 (de) |
EP (1) | EP2010179B1 (de) |
JP (1) | JP2009533449A (de) |
AT (1) | ATE473004T1 (de) |
AU (1) | AU2007238744A1 (de) |
CA (1) | CA2650401A1 (de) |
DE (1) | DE602007007594D1 (de) |
WO (1) | WO2007120718A2 (de) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101466698A (zh) | 2006-04-14 | 2009-06-24 | 默克公司 | 作为缩胆囊素-1受体调节剂的取代的咪唑4-甲酰胺类化合物 |
CA2649927A1 (en) | 2006-04-14 | 2007-10-25 | Merck & Co., Inc. | Substituted imidazole 4-carboxamides as cholecystokinin-1 receptor modulators |
WO2009001915A1 (ja) * | 2007-06-28 | 2008-12-31 | Takeda Pharmaceutical Company Limited | 置換イミダゾール化合物およびその用途 |
WO2010067233A1 (en) | 2008-12-08 | 2010-06-17 | Pfizer Inc. | 1,2,4 triazolo [4, 3 -a] [1,5] benzodiazepin-5 (6h) -ones as agonists of the cholecystokinin-1 receptor (cck-ir) |
US8871758B2 (en) | 2011-03-08 | 2014-10-28 | Sanofi | Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof |
WO2012120052A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
EP2683705B1 (de) | 2011-03-08 | 2015-04-22 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
WO2012120055A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
WO2012120053A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
EP2567959B1 (de) | 2011-09-12 | 2014-04-16 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridin-4-carbonsäureamid-derivate als kinaseinhibitoren |
JP7268049B2 (ja) | 2018-03-08 | 2023-05-02 | インサイト・コーポレイション | PI3K-γ阻害剤としてのアミノピラジンジオール化合物 |
US11046658B2 (en) | 2018-07-02 | 2021-06-29 | Incyte Corporation | Aminopyrazine derivatives as PI3K-γ inhibitors |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2133355A1 (en) | 1993-10-04 | 1995-04-05 | Itaru Nitta | Method for producing polypeptide |
GB0011089D0 (en) * | 2000-05-08 | 2000-06-28 | Black James Foundation | Gastrin and cholecystokinin receptor ligands (11) |
US20040072865A1 (en) | 2001-01-15 | 2004-04-15 | Bouillot Anne Marie Jeanne | Aryl piperidine derivatives as inducers of ldl-receptor expression |
WO2003007887A2 (en) | 2001-07-20 | 2003-01-30 | Merck & Co., Inc. | Substituted imidazoles as cannabinoid receptor modulators |
US7109216B2 (en) | 2001-09-21 | 2006-09-19 | Solvay Pharmaceuticals B.V. | 1H-imidazole derivatives having CB1 agonistic, CB1 partial agonistic or CB1-antagonistic activity |
AR036608A1 (es) | 2001-09-24 | 2004-09-22 | Bayer Corp | Derivados de imidazol, composiciones farmaceuticas y el uso de dichos derivados para la fabricacion de un medicamento para el tratamiento de la obesidad |
WO2003063781A2 (en) | 2002-01-29 | 2003-08-07 | Merck & Co., Inc. | Substituted imidazoles as cannabinoid receptor modulators |
UA79804C2 (en) | 2002-07-03 | 2007-07-25 | Janssen Pharmaceutica Nv | Cck-1 receptor modulators |
PL378841A1 (pl) | 2003-04-21 | 2006-05-29 | Daiichi Pharmaceutical Co., Ltd. | Pochodna pięcioczłonowego układu heterocyklicznego |
US20050026983A1 (en) | 2003-07-30 | 2005-02-03 | Pfizer Inc | Imidazole compounds and uses thereof |
DE602004031245D1 (de) | 2003-10-20 | 2011-03-10 | Abbott Healthcare Products Bv | 1h-imidazolderivate als modulatoren des cannabinoidrezeptors |
US20050124660A1 (en) | 2003-10-27 | 2005-06-09 | Jochen Antel | Novel medical uses of compounds showing CB1-antagonistic activity and combination treatment involving said compounds |
US7250434B2 (en) | 2003-12-22 | 2007-07-31 | Janssen Pharmaceutica N.V. | CCK-1 receptor modulators |
CA2560417C (en) | 2004-04-03 | 2011-04-19 | Astrazeneca Ab | 1,2-diarylimidazole-4-carboxamide derivatives |
CA2649927A1 (en) | 2006-04-14 | 2007-10-25 | Merck & Co., Inc. | Substituted imidazole 4-carboxamides as cholecystokinin-1 receptor modulators |
CN101466698A (zh) | 2006-04-14 | 2009-06-24 | 默克公司 | 作为缩胆囊素-1受体调节剂的取代的咪唑4-甲酰胺类化合物 |
-
2007
- 2007-04-10 JP JP2009505461A patent/JP2009533449A/ja not_active Withdrawn
- 2007-04-10 US US12/226,115 patent/US7759352B2/en not_active Expired - Fee Related
- 2007-04-10 WO PCT/US2007/008956 patent/WO2007120718A2/en active Application Filing
- 2007-04-10 AT AT07755283T patent/ATE473004T1/de not_active IP Right Cessation
- 2007-04-10 DE DE602007007594T patent/DE602007007594D1/de active Active
- 2007-04-10 EP EP07755283A patent/EP2010179B1/de not_active Not-in-force
- 2007-04-10 CA CA002650401A patent/CA2650401A1/en not_active Abandoned
- 2007-04-10 AU AU2007238744A patent/AU2007238744A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2007120718A3 (en) | 2008-07-24 |
US20090281117A1 (en) | 2009-11-12 |
WO2007120718A2 (en) | 2007-10-25 |
DE602007007594D1 (de) | 2010-08-19 |
EP2010179A4 (de) | 2009-05-06 |
EP2010179B1 (de) | 2010-07-07 |
CA2650401A1 (en) | 2007-10-25 |
AU2007238744A1 (en) | 2007-10-25 |
EP2010179A2 (de) | 2009-01-07 |
JP2009533449A (ja) | 2009-09-17 |
US7759352B2 (en) | 2010-07-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |