MX2007002583A - Metodos y composiciones para realzar la degradacion de factores de transcripcion del receptor nuclear y sus usos. - Google Patents

Metodos y composiciones para realzar la degradacion de factores de transcripcion del receptor nuclear y sus usos.

Info

Publication number
MX2007002583A
MX2007002583A MX2007002583A MX2007002583A MX2007002583A MX 2007002583 A MX2007002583 A MX 2007002583A MX 2007002583 A MX2007002583 A MX 2007002583A MX 2007002583 A MX2007002583 A MX 2007002583A MX 2007002583 A MX2007002583 A MX 2007002583A
Authority
MX
Mexico
Prior art keywords
compositions
nuclear receptor
methods
transcription factors
receptor transcription
Prior art date
Application number
MX2007002583A
Other languages
English (en)
Inventor
Charles C Y Shih
Ching-Yuan Su
Original Assignee
Androscience Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/045,181 external-priority patent/US20050209205A1/en
Application filed by Androscience Corp filed Critical Androscience Corp
Publication of MX2007002583A publication Critical patent/MX2007002583A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28—Antiandrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Dermatology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invencion incluye metodos, composiciones, composiciones cosmeticas y farmaceuticas para mejorar la degradacion del receptor nuclear (NR) o un factor de transcripcion de proteina STAT. Los metodos, composiciones, cosmeticas y farmaceuticas pueden ser utilizadas para prevenir o tratar desordenes o condiciones medicas que son al menos en parte afectada por el camino de activacion del receptor nuclear o el camino de activacion de STAT.
MX2007002583A 2004-09-02 2005-09-02 Metodos y composiciones para realzar la degradacion de factores de transcripcion del receptor nuclear y sus usos. MX2007002583A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US60667804P 2004-09-02 2004-09-02
US11/045,181 US20050209205A1 (en) 2004-01-28 2005-01-27 Enhancement of anti-androgenic activity by a combination of inhibitors targeting different steps of a steroid-dependent gene activation pathway and uses thereof
PCT/US2005/031447 WO2006029040A2 (en) 2004-09-02 2005-09-02 Methods and compositions for enhancing degradation of nuclear receptor transcription factors and uses thereof

Publications (1)

Publication Number Publication Date
MX2007002583A true MX2007002583A (es) 2007-09-14

Family

ID=36036907

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007002583A MX2007002583A (es) 2004-09-02 2005-09-02 Metodos y composiciones para realzar la degradacion de factores de transcripcion del receptor nuclear y sus usos.

Country Status (6)

Country Link
EP (1) EP1804806A2 (es)
JP (1) JP2008540327A (es)
AU (1) AU2005282624A1 (es)
CA (1) CA2578159A1 (es)
MX (1) MX2007002583A (es)
WO (1) WO2006029040A2 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5292569B2 (ja) * 2006-11-10 2013-09-18 国立大学法人名古屋大学 抗老化転写因子活性化剤及びその利用
US9000222B2 (en) 2007-01-08 2015-04-07 Androscience Corporation Compounds with (1E, 6E)-1,7-bis-(3,4-dimethoxyphenyl)-4,4-disubstituted-hepta-1,6-diene-3,5-dione structural scaffold, their biological activity, and uses thereof
KR101563370B1 (ko) 2007-01-08 2015-10-26 앤드로사이언스 코포레이션 (치환된 페닐)-프로페날 잔기를 갖는 화합물, 이의 유도체, 생물학적 활성, 및 이의 용도
US8710272B2 (en) 2007-01-08 2014-04-29 Androscience Corporation Compounds with (1 E, 6E)-1,7-bis-(3,4-dimethoxyphenyl)-4,4-disubstituted-hepta-1,6-diene-3,5-dione structural scaffold, their biological activity, and uses thereof
WO2009017815A1 (en) 2007-07-31 2009-02-05 Androscience Corporation Compositions including androgen receptor degradation (ard) enhancers and methods of prophylactic or therapeutic treatment of skin disorders and hair loss

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2770842B1 (fr) * 1997-11-13 1999-12-17 Oreal Nouveaux composes derives de n-aryl 2-hydroxy alkylamides
US6790979B2 (en) * 2002-04-17 2004-09-14 University Of North Carolina At Chapel Hill Curcumin analogues and uses thereof
CA2515589A1 (en) * 2003-02-11 2004-08-26 Warner-Lambert Company Llc Urea and thiourea derivatives

Also Published As

Publication number Publication date
WO2006029040A3 (en) 2008-12-04
AU2005282624A1 (en) 2006-03-16
EP1804806A2 (en) 2007-07-11
WO2006029040A2 (en) 2006-03-16
JP2008540327A (ja) 2008-11-20
CA2578159A1 (en) 2006-03-16

Similar Documents

Publication Publication Date Title
CY1119766T1 (el) Νεοι ρυθμιστες κινασης βενζοπυρανιου
MX2009006339A (es) Compuestos y composiciones como inhibidores de actividad de receptor 1 de cannabinoide.
TN2010000122A1 (en) Compounds and compositions as modulators of gpr119 activity
MX2009009491A (es) Compuestos y composiciones como moduladores de la actividad del gpr119.
MX2007009356A (es) Compuestos y composiciones como moduladores de ppar.
TW200611695A (en) Pyrrolopyridine derivatives
TNSN07161A1 (en) Compounds and compositions as inhibitors of cannabinoid receptor 1 activity
NO20065984L (no) Forbindelser og sammensetninger som PPAR modulatorer
MX2008012400A (es) Azolopirimidinas como inhibidores de actividad de cannabinoide 1.
PL1979355T3 (pl) Pochodne spiro imidazoli jako modulatory PPAR
UA83194C2 (ru) Производные пиримидина и их применение как модуляторов св2
TW200602330A (en) Compounds and compositions as PPAR modulators
NO20065983L (no) Forbindelser og sammensetninger som PPAR modulatorer
MX2009008159A (es) Compuestos y composiciones como moduladores de la actividad de gpr119.
BRPI0918868B8 (pt) compostos moduladores do receptor de nmda e composições compreendendo os mesmos
NO20070081L (no) Sulfamat og sulfamidderivater for behandling av epilepsi og relaterte sykdommer
WO2009076454A3 (en) Compounds that modulate intracellular calcium
GB0222495D0 (en) Compounds
MY149855A (en) Benzimidazole derivatives and their use for modulating the gaba? receptor complex
PL1910338T3 (pl) Związki heterotetracykliczne jako mimetyki TPO
MX2022007155A (es) Derivados de cromano novedosos que tienen actividad de degradacion de receptor de estrogeno y usos de los mismos.
JO2645B1 (en) Vehicles
NO20084792L (no) Substituerte imidazol-4-karboksamider som kolecystokinin-1-reseptormodulatorer
MX2008002166A (es) Compuestos y composiciones como mimeticos de trombopoietina (tpo).
MX2010006206A (es) Derivados de oxindol substituidos por 5-halogeno y el uso de los mismos para el tratamiento de enfermedades dependientes de la vasopresina.

Legal Events

Date Code Title Description
FA Abandonment or withdrawal