DE602007007594D1 - Substituierte imidazol-4-carboxamide als cholecystokinin-1-rezeptor-modulatoren - Google Patents
Substituierte imidazol-4-carboxamide als cholecystokinin-1-rezeptor-modulatorenInfo
- Publication number
- DE602007007594D1 DE602007007594D1 DE602007007594T DE602007007594T DE602007007594D1 DE 602007007594 D1 DE602007007594 D1 DE 602007007594D1 DE 602007007594 T DE602007007594 T DE 602007007594T DE 602007007594 T DE602007007594 T DE 602007007594T DE 602007007594 D1 DE602007007594 D1 DE 602007007594D1
- Authority
- DE
- Germany
- Prior art keywords
- carboxamides
- cholecystokinin
- substituted imidazole
- receptor modulators
- receptor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US79213406P | 2006-04-14 | 2006-04-14 | |
PCT/US2007/008956 WO2007120718A2 (en) | 2006-04-14 | 2007-04-10 | Substituted imidazole 4-carboxamides as cholecystokinin-1 receptor modulators |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602007007594D1 true DE602007007594D1 (de) | 2010-08-19 |
Family
ID=38610151
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602007007594T Active DE602007007594D1 (de) | 2006-04-14 | 2007-04-10 | Substituierte imidazol-4-carboxamide als cholecystokinin-1-rezeptor-modulatoren |
Country Status (8)
Country | Link |
---|---|
US (1) | US7759352B2 (de) |
EP (1) | EP2010179B1 (de) |
JP (1) | JP2009533449A (de) |
AT (1) | ATE473004T1 (de) |
AU (1) | AU2007238744A1 (de) |
CA (1) | CA2650401A1 (de) |
DE (1) | DE602007007594D1 (de) |
WO (1) | WO2007120718A2 (de) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2007238804A1 (en) | 2006-04-14 | 2007-10-25 | Merck Sharp & Dohme Corp. | Substituted imidazole 4-carboxamides as cholecystokinin-1 receptor modulators |
BRPI0709972A2 (pt) | 2006-04-14 | 2011-08-02 | Merck & Co Inc | composto, composição farmacêutica, e, uso de um composto |
WO2009001915A1 (ja) * | 2007-06-28 | 2008-12-31 | Takeda Pharmaceutical Company Limited | 置換イミダゾール化合物およびその用途 |
WO2010067233A1 (en) | 2008-12-08 | 2010-06-17 | Pfizer Inc. | 1,2,4 triazolo [4, 3 -a] [1,5] benzodiazepin-5 (6h) -ones as agonists of the cholecystokinin-1 receptor (cck-ir) |
WO2012120052A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
US8828995B2 (en) | 2011-03-08 | 2014-09-09 | Sanofi | Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
EP2683700B1 (de) | 2011-03-08 | 2015-02-18 | Sanofi | Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
WO2012120054A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
WO2012120055A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
EP2567959B1 (de) | 2011-09-12 | 2014-04-16 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridin-4-carbonsäureamid-derivate als kinaseinhibitoren |
PL3762368T3 (pl) | 2018-03-08 | 2022-06-06 | Incyte Corporation | ZWIĄZKI AMINOPIRAZYNODIOLOWE JAKO INHIBITORY PI3K-γ |
US11046658B2 (en) | 2018-07-02 | 2021-06-29 | Incyte Corporation | Aminopyrazine derivatives as PI3K-γ inhibitors |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2133355A1 (en) | 1993-10-04 | 1995-04-05 | Itaru Nitta | Method for producing polypeptide |
GB0011089D0 (en) * | 2000-05-08 | 2000-06-28 | Black James Foundation | Gastrin and cholecystokinin receptor ligands (11) |
US20040072865A1 (en) | 2001-01-15 | 2004-04-15 | Bouillot Anne Marie Jeanne | Aryl piperidine derivatives as inducers of ldl-receptor expression |
WO2003007887A2 (en) | 2001-07-20 | 2003-01-30 | Merck & Co., Inc. | Substituted imidazoles as cannabinoid receptor modulators |
US7109216B2 (en) | 2001-09-21 | 2006-09-19 | Solvay Pharmaceuticals B.V. | 1H-imidazole derivatives having CB1 agonistic, CB1 partial agonistic or CB1-antagonistic activity |
GT200200188A (es) | 2001-09-24 | 2003-06-25 | Preparacion y uso de derivados de imidazol para el tratamiento de la obesidad | |
AU2003209388A1 (en) | 2002-01-29 | 2003-09-02 | Merck And Co., Inc. | Substituted imidazoles as cannabinoid receptor modulators |
UA79804C2 (en) | 2002-07-03 | 2007-07-25 | Janssen Pharmaceutica Nv | Cck-1 receptor modulators |
EP1621537A4 (de) | 2003-04-21 | 2008-12-31 | Daiichi Seiyaku Co | Fünfgliedriges heterocyclisches derivat |
US20050026983A1 (en) | 2003-07-30 | 2005-02-03 | Pfizer Inc | Imidazole compounds and uses thereof |
ATE496896T1 (de) | 2003-10-20 | 2011-02-15 | Abbott Healthcare Products Bv | 1h-imidazolderivate als modulatoren des cannabinoidrezeptors |
US20050124660A1 (en) | 2003-10-27 | 2005-06-09 | Jochen Antel | Novel medical uses of compounds showing CB1-antagonistic activity and combination treatment involving said compounds |
WO2005063716A1 (en) * | 2003-12-22 | 2005-07-14 | Janssen Pharmaceutica, N.V. | Imidazoles and their use cck-1 receptor modulators |
US7799804B2 (en) | 2004-04-03 | 2010-09-21 | Astrazeneca Ab | Therapeutic agents |
AU2007238804A1 (en) | 2006-04-14 | 2007-10-25 | Merck Sharp & Dohme Corp. | Substituted imidazole 4-carboxamides as cholecystokinin-1 receptor modulators |
BRPI0709972A2 (pt) | 2006-04-14 | 2011-08-02 | Merck & Co Inc | composto, composição farmacêutica, e, uso de um composto |
-
2007
- 2007-04-10 AT AT07755283T patent/ATE473004T1/de not_active IP Right Cessation
- 2007-04-10 AU AU2007238744A patent/AU2007238744A1/en not_active Abandoned
- 2007-04-10 EP EP07755283A patent/EP2010179B1/de not_active Not-in-force
- 2007-04-10 WO PCT/US2007/008956 patent/WO2007120718A2/en active Application Filing
- 2007-04-10 DE DE602007007594T patent/DE602007007594D1/de active Active
- 2007-04-10 JP JP2009505461A patent/JP2009533449A/ja not_active Withdrawn
- 2007-04-10 CA CA002650401A patent/CA2650401A1/en not_active Abandoned
- 2007-04-10 US US12/226,115 patent/US7759352B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US7759352B2 (en) | 2010-07-20 |
ATE473004T1 (de) | 2010-07-15 |
EP2010179A2 (de) | 2009-01-07 |
AU2007238744A1 (en) | 2007-10-25 |
WO2007120718A2 (en) | 2007-10-25 |
US20090281117A1 (en) | 2009-11-12 |
JP2009533449A (ja) | 2009-09-17 |
EP2010179A4 (de) | 2009-05-06 |
WO2007120718A3 (en) | 2008-07-24 |
EP2010179B1 (de) | 2010-07-07 |
CA2650401A1 (en) | 2007-10-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE515504T1 (de) | Substituierte imidazol-4-carboxamide als cholecystokinin-1-rezeptor-modulatoren | |
DE602007007594D1 (de) | Substituierte imidazol-4-carboxamide als cholecystokinin-1-rezeptor-modulatoren | |
DE602007008868D1 (de) | Substituierte imidazol-4-carboxamide als cholecystokinin-1-rezeptor-modulatoren | |
WO2008008286A3 (en) | Substituted pyrazoles as ghrelin receptor antagonists | |
NO20084374L (no) | Imidazoltiazolforbindelser for behandling av sykdom | |
EP2217596B8 (de) | Bicyclische heterocyclische derivate und ihre verwendung als modulatoren der aktivität von gpr 119 | |
ATE516300T1 (de) | Neuromedin-u-rezeptoragonisten und ihre verwendung | |
DE60309739D1 (de) | Pyridinderivate als modulatoren des cb2-rezeptors | |
EA201001329A1 (ru) | Соединения и композиции в качестве модуляторов активности gpr119 | |
TW200745126A (en) | Bicyclic heteroaryl derivatives as cannabinoid receptor modulators | |
EA200700262A1 (ru) | Арилидены для лечения заболеваний, опосредуемых эстроген-родственным рецепторам альфа | |
EA200800835A1 (ru) | Циклопропиламины в качестве модуляторов рецептора гистамина н | |
EA201001332A1 (ru) | Соединения и композиции в качестве модуляторов активности gpr119 | |
MY149855A (en) | Benzimidazole derivatives and their use for modulating the gaba? receptor complex | |
MX2010006206A (es) | Derivados de oxindol substituidos por 5-halogeno y el uso de los mismos para el tratamiento de enfermedades dependientes de la vasopresina. | |
EA201001330A1 (ru) | Соединения и композиции в качестве модуляторов активности gpr119 | |
MY146506A (en) | Substituted pyridyl amide compounds as modulators of the histamine h3 receptor | |
DE602007009873D1 (de) | Substituierte diazepin-sulfonamide als bombesin-rezeptor-subtyp-3-modulatoren | |
MX2009004112A (es) | Imidazoles sustituidos como moduladores del receptor de bombesina subtipo-3. | |
EA201070637A1 (ru) | Соединения циклоалкилокси- и гетероциклоалкилоксипиридина как модуляторы гистаминового рецептора н | |
NO20083045L (no) | Benzimidazolderivater og deres anvendelse til modulering av GABAA-reseptorkomplekset | |
ATE473741T1 (de) | Neue imidazolopyrazolderivate als selektive androgen-rezeptor-modulatoren | |
MX2009009364A (es) | Compuestos de indol y benzotiofeno como moduladores del receptor de histamina h3. | |
ATE528006T1 (de) | Substituierte aminopyrimidine als cholecystokinin-1-rezeptormodulatoren | |
MX2007002583A (es) | Metodos y composiciones para realzar la degradacion de factores de transcripcion del receptor nuclear y sus usos. |