EA200401551A1 - Получение сульфинилацетамида - Google Patents

Получение сульфинилацетамида

Info

Publication number
EA200401551A1
EA200401551A1 EA200401551A EA200401551A EA200401551A1 EA 200401551 A1 EA200401551 A1 EA 200401551A1 EA 200401551 A EA200401551 A EA 200401551A EA 200401551 A EA200401551 A EA 200401551A EA 200401551 A1 EA200401551 A1 EA 200401551A1
Authority
EA
Eurasian Patent Office
Prior art keywords
sulphinylacetamide
obtaining
chloroacetamide
provides methods
present
Prior art date
Application number
EA200401551A
Other languages
English (en)
Other versions
EA007561B1 (ru
Inventor
Дени Ларжо
Жилль Оддон
Original Assignee
Сефалон, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Сефалон, Инк. filed Critical Сефалон, Инк.
Publication of EA200401551A1 publication Critical patent/EA200401551A1/ru
Publication of EA007561B1 publication Critical patent/EA007561B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C07C315/02—Preparation of sulfones; Preparation of sulfoxides by formation of sulfone or sulfoxide groups by oxidation of sulfides, or by formation of sulfone groups by oxidation of sulfoxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10—Sulfides; Sulfoxides; Sulfones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Данное изобретение предоставляет способы получения модафинила, которые включают стадию взаимодействия бензгидрилтиола с хлорацетамидом.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200401551A 2002-05-23 2003-05-23 Получение сульфинилацетамида EA007561B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US38317302P 2002-05-23 2002-05-23
US10/443,327 US6875893B2 (en) 2002-05-23 2003-05-22 Preparations of a sulfinyl acetamide
PCT/US2003/016379 WO2003099774A1 (en) 2002-05-23 2003-05-23 Preparations of a sulfinyl acetamide

Publications (2)

Publication Number Publication Date
EA200401551A1 true EA200401551A1 (ru) 2005-04-28
EA007561B1 EA007561B1 (ru) 2006-12-29

Family

ID=29586987

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200401551A EA007561B1 (ru) 2002-05-23 2003-05-23 Получение сульфинилацетамида

Country Status (29)

Country Link
US (2) US6875893B2 (ru)
EP (1) EP1506171B1 (ru)
JP (1) JP4351627B2 (ru)
KR (1) KR100984571B1 (ru)
CN (1) CN100379721C (ru)
AR (1) AR039857A1 (ru)
AT (1) ATE414058T1 (ru)
BR (1) BR0311242A (ru)
CA (1) CA2486533C (ru)
CY (1) CY1108747T1 (ru)
DE (1) DE60324671D1 (ru)
DK (1) DK1506171T3 (ru)
EA (1) EA007561B1 (ru)
EG (1) EG23693A (ru)
ES (1) ES2316755T3 (ru)
HK (1) HK1072596A1 (ru)
IL (2) IL165095A0 (ru)
IS (1) IS2650B (ru)
MX (1) MXPA04011459A (ru)
MY (1) MY129141A (ru)
NO (1) NO329559B1 (ru)
NZ (1) NZ536747A (ru)
PL (1) PL211695B1 (ru)
PT (1) PT1506171E (ru)
SI (1) SI1506171T1 (ru)
TW (1) TWI317733B (ru)
UA (1) UA79790C2 (ru)
WO (1) WO2003099774A1 (ru)
ZA (1) ZA200409400B (ru)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1309547E (pt) 2000-07-27 2007-03-30 Teva Pharma Modafinil cristalino e puro, e processo para a sua preparação
US6875893B2 (en) * 2002-05-23 2005-04-05 Cephalon, Inc. Preparations of a sulfinyl acetamide
US6992219B2 (en) * 2002-08-09 2006-01-31 Cephalon France Modafinil polymorphic forms
FR2849029B1 (fr) * 2002-12-20 2005-03-18 Lafon Labor Procede de preparation et formes cristallines des enantiomeres optiques du modafinil.
EP1603867A2 (en) * 2003-02-24 2005-12-14 Mallinckrodt Inc. Process for preparing benzhydrylthioacetamide
US20040253308A1 (en) * 2003-04-29 2004-12-16 Barr Laboratories, Inc. Surface-treated modafinil particles
US7368591B2 (en) 2003-09-19 2008-05-06 Cephalon France Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation
CA2543326A1 (en) * 2003-10-23 2005-05-12 Mallinckrodt Inc. Improved process for preparing benzhydrylthioacetamide
US20060086667A1 (en) * 2004-09-13 2006-04-27 Cephalon, Inc., U.S. Corporation Methods for the separation of enantiomeric sulfinylacetamides
PT1737889E (pt) 2004-10-19 2010-12-13 Lonza Ag Método para síntese de péptidos em fase sólida
AU2006272874B2 (en) * 2005-07-21 2010-03-11 Neurohealing Pharmaceuticals, Inc. Rapid onset and short term modafinil compositions and methods of use thereof
US7553646B2 (en) * 2005-07-28 2009-06-30 University Of Iowa Research Foundation Microbial sulfoxidation and amidation of benzhdrylsulfanyl carboxylic acids and uses thereof
CA2618494A1 (en) * 2005-09-14 2007-03-22 Novetide, Ltd. Process for production of bivalirudin
CA2632722A1 (en) * 2005-12-09 2007-06-21 Mallinckrodt Inc. Processes for the preparation of modafinil and analogs thereof
CN100343228C (zh) * 2006-02-17 2007-10-17 中国科学院上海有机化学研究所 高对映体选择性制备 2－二苯甲基亚磺酰基－乙酰胺单一对映体的方法
WO2007098273A2 (en) * 2006-02-21 2007-08-30 Teva Pharmaceutical Industries Ltd. Novel crystalline forms of armodafinil and preparation thereof
US20080031939A1 (en) * 2006-03-01 2008-02-07 Viviana Braude Process for the preparation of armodafinil
GB0604233D0 (en) * 2006-03-02 2006-04-12 Syngenta Participations Ag Process
CA2657409A1 (en) * 2006-07-12 2008-01-17 Elan Corporation, Plc Nanoparticulate formulations of modafinil
CA2660565C (en) * 2006-08-14 2012-10-09 Neurohealing Pharmaceuticals, Inc. Modafinil-based treatment for premature ejaculation
WO2009025791A2 (en) * 2007-08-16 2009-02-26 Teva Pharmaceutical Industries Ltd. Purification of armodafinil
US20100036164A1 (en) * 2008-08-06 2010-02-11 Srinivas Areveli Preparation of armodafinil form i
CN102976985A (zh) * 2011-09-07 2013-03-20 大连大学 一锅法合成二苯甲基亚磺酰基乙酰胺及其类似物的方法
EP3102492B1 (en) * 2014-02-06 2020-04-15 BillerudKorsnäs AB A method for producing stand-up pouches of stretchable paper

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1520812A (en) * 1975-10-02 1978-08-09 Lafon Labor Benzhydrylsulphinyl derivatives
GB1584462A (en) * 1977-03-31 1981-02-11 Lafon Labor N-diaryl-malonamide and diarylmethyl-sulphinyl-acetamide derivatives and pharmaceutical compositions containing them
FR2593809B1 (fr) * 1986-01-31 1988-07-22 Lafon Labor Benzhydrylsulfinylacetamide, procede de preparation et utilisation en therapeutique
CA2416384A1 (en) * 2000-07-17 2003-01-16 Takeda Chemical Industries, Ltd. Sulfone derivatives, their production and use
PT1309547E (pt) 2000-07-27 2007-03-30 Teva Pharma Modafinil cristalino e puro, e processo para a sua preparação
IL143106A (en) 2001-05-13 2005-11-20 Chemagis Ltd Process for the preparation of diphenylmethylthioacetamide
US6875893B2 (en) * 2002-05-23 2005-04-05 Cephalon, Inc. Preparations of a sulfinyl acetamide
DE10245546B3 (de) * 2002-09-30 2004-05-13 Infineon Technologies Ag Pseudostatische Speicherschaltung
JP3838972B2 (ja) * 2002-12-25 2006-10-25 Ｎｅｃエレクトロニクス株式会社 周波数検出回路及びデータ処理装置

Also Published As

Publication number Publication date
UA79790C2 (en) 2007-07-25
ES2316755T3 (es) 2009-04-16
CY1108747T1 (el) 2014-04-09
KR20050016421A (ko) 2005-02-21
AR039857A1 (es) 2005-03-02
WO2003099774A1 (en) 2003-12-04
NZ536747A (en) 2006-11-30
EG23693A (en) 2007-05-15
EA007561B1 (ru) 2006-12-29
JP4351627B2 (ja) 2009-10-28
ZA200409400B (en) 2005-12-28
BR0311242A (pt) 2005-03-15
NO20044916L (no) 2004-12-16
US20050171209A1 (en) 2005-08-04
US7057069B2 (en) 2006-06-06
TW200406196A (en) 2004-05-01
AU2003233668A1 (en) 2003-12-12
HK1072596A1 (en) 2005-09-02
SI1506171T1 (sl) 2009-06-30
EP1506171A1 (en) 2005-02-16
CN1656064A (zh) 2005-08-17
JP2005527623A (ja) 2005-09-15
ATE414058T1 (de) 2008-11-15
IL165095A (en) 2010-11-30
US6875893B2 (en) 2005-04-05
MXPA04011459A (es) 2005-02-14
PT1506171E (pt) 2009-01-02
CN100379721C (zh) 2008-04-09
IS2650B (is) 2010-08-15
DE60324671D1 (de) 2008-12-24
DK1506171T3 (da) 2009-01-19
TWI317733B (en) 2009-12-01
US20040002547A1 (en) 2004-01-01
PL211695B1 (pl) 2012-06-29
NO329559B1 (no) 2010-11-15
PL373792A1 (en) 2005-09-19
EP1506171B1 (en) 2008-11-12
KR100984571B1 (ko) 2010-09-30
MY129141A (en) 2007-03-30
IL165095A0 (en) 2005-12-18
IS7523A (is) 2004-11-09
CA2486533A1 (en) 2003-12-04
CA2486533C (en) 2011-01-04

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): RU