MXPA04011459A - Preparaciones de una sulfinilacetamida. - Google Patents

Preparaciones de una sulfinilacetamida.

Info

Publication number
MXPA04011459A
MXPA04011459A MXPA04011459A MXPA04011459A MXPA04011459A MX PA04011459 A MXPA04011459 A MX PA04011459A MX PA04011459 A MXPA04011459 A MX PA04011459A MX PA04011459 A MXPA04011459 A MX PA04011459A MX PA04011459 A MXPA04011459 A MX PA04011459A
Authority
MX
Mexico
Prior art keywords
preparations
sulfinyl acetamide
sulfinyl
acetamide
modafinil
Prior art date
Application number
MXPA04011459A
Other languages
English (en)
Inventor
Oddon Gilles
Original Assignee
Cephalon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cephalon Inc filed Critical Cephalon Inc
Publication of MXPA04011459A publication Critical patent/MXPA04011459A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C07C315/02—Preparation of sulfones; Preparation of sulfoxides by formation of sulfone or sulfoxide groups by oxidation of sulfides, or by formation of sulfone groups by oxidation of sulfoxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10—Sulfides; Sulfoxides; Sulfones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides

Abstract

La presente invencion proporciona procedimientos para la preparacion de modafinilo, que incluye la etapa de la reaccion de benzhidriltiol y cloroacetamida.
MXPA04011459A 2002-05-23 2003-05-23 Preparaciones de una sulfinilacetamida. MXPA04011459A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US38317302P 2002-05-23 2002-05-23
US10/443,327 US6875893B2 (en) 2002-05-23 2003-05-22 Preparations of a sulfinyl acetamide
PCT/US2003/016379 WO2003099774A1 (en) 2002-05-23 2003-05-23 Preparations of a sulfinyl acetamide

Publications (1)

Publication Number Publication Date
MXPA04011459A true MXPA04011459A (es) 2005-02-14

Family

ID=29586987

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA04011459A MXPA04011459A (es) 2002-05-23 2003-05-23 Preparaciones de una sulfinilacetamida.

Country Status (29)

Country Link
US (2) US6875893B2 (es)
EP (1) EP1506171B1 (es)
JP (1) JP4351627B2 (es)
KR (1) KR100984571B1 (es)
CN (1) CN100379721C (es)
AR (1) AR039857A1 (es)
AT (1) ATE414058T1 (es)
BR (1) BR0311242A (es)
CA (1) CA2486533C (es)
CY (1) CY1108747T1 (es)
DE (1) DE60324671D1 (es)
DK (1) DK1506171T3 (es)
EA (1) EA007561B1 (es)
EG (1) EG23693A (es)
ES (1) ES2316755T3 (es)
HK (1) HK1072596A1 (es)
IL (2) IL165095A0 (es)
IS (1) IS2650B (es)
MX (1) MXPA04011459A (es)
MY (1) MY129141A (es)
NO (1) NO329559B1 (es)
NZ (1) NZ536747A (es)
PL (1) PL211695B1 (es)
PT (1) PT1506171E (es)
SI (1) SI1506171T1 (es)
TW (1) TWI317733B (es)
UA (1) UA79790C2 (es)
WO (1) WO2003099774A1 (es)
ZA (1) ZA200409400B (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002010125A1 (en) * 2000-07-27 2002-02-07 Teva Pharmaceutical Industries Ltd. Crystalline and pure modafinil, and process of preparing the same
US6875893B2 (en) * 2002-05-23 2005-04-05 Cephalon, Inc. Preparations of a sulfinyl acetamide
US6992219B2 (en) * 2002-08-09 2006-01-31 Cephalon France Modafinil polymorphic forms
FR2849029B1 (fr) * 2002-12-20 2005-03-18 Lafon Labor Procede de preparation et formes cristallines des enantiomeres optiques du modafinil.
CN1753867A (zh) * 2003-02-24 2006-03-29 马林克罗特公司 制备二苯甲基硫代乙酰胺的方法
US20040253308A1 (en) * 2003-04-29 2004-12-16 Barr Laboratories, Inc. Surface-treated modafinil particles
US7368591B2 (en) 2003-09-19 2008-05-06 Cephalon France Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation
ATE410410T1 (de) * 2003-10-23 2008-10-15 Mallinckrodt Inc Verbessertes verfahren zur herstellung von benzhydrylthioacetamid.
US20060086667A1 (en) * 2004-09-13 2006-04-27 Cephalon, Inc., U.S. Corporation Methods for the separation of enantiomeric sulfinylacetamides
CN101094867B (zh) 2004-10-19 2011-08-24 隆萨股份公司 用于固相肽合成的方法
CA2614777C (en) * 2005-07-21 2012-04-17 Neurohealing Pharmaceuticals, Inc. Rapid onset and short term modafinil compositions and methods of use thereof
US7553646B2 (en) * 2005-07-28 2009-06-30 University Of Iowa Research Foundation Microbial sulfoxidation and amidation of benzhdrylsulfanyl carboxylic acids and uses thereof
JP2008543884A (ja) * 2005-09-14 2008-12-04 ノベタイド，リミティド ビバリルジンの生成方法
CN101326159A (zh) * 2005-12-09 2008-12-17 马林克罗特公司 制备莫达非尼及其类似物的方法
CN100343228C (zh) * 2006-02-17 2007-10-17 中国科学院上海有机化学研究所 高对映体选择性制备 2－二苯甲基亚磺酰基－乙酰胺单一对映体的方法
EP1986994A2 (en) * 2006-02-21 2008-11-05 Teva Pharmaceutical Industries Ltd Novel crystalline forms of armodafinil and preparation thereof
EP2159219A3 (en) * 2006-03-01 2010-12-15 Teva Pharmaceutical Industries Ltd. An improved process for the preparation of armodafinil
GB0604233D0 (en) * 2006-03-02 2006-04-12 Syngenta Participations Ag Process
KR20090031618A (ko) * 2006-07-12 2009-03-26 엘란 코포레이션, 피엘씨 나노입자형 모다피닐 제제
US7884135B2 (en) * 2006-08-14 2011-02-08 Neurohealing Pharmaceuticals, Inc. Modafinil-based treatment for premature ejaculation
WO2009025791A2 (en) * 2007-08-16 2009-02-26 Teva Pharmaceutical Industries Ltd. Purification of armodafinil
US20100036164A1 (en) * 2008-08-06 2010-02-11 Srinivas Areveli Preparation of armodafinil form i
CN102976985A (zh) * 2011-09-07 2013-03-20 大连大学 一锅法合成二苯甲基亚磺酰基乙酰胺及其类似物的方法
CN105992734A (zh) * 2014-02-06 2016-10-05 比勒鲁迪克斯那斯公司 由可拉伸的纸构成的直立袋

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1520812A (en) 1975-10-02 1978-08-09 Lafon Labor Benzhydrylsulphinyl derivatives
GB1584462A (en) * 1977-03-31 1981-02-11 Lafon Labor N-diaryl-malonamide and diarylmethyl-sulphinyl-acetamide derivatives and pharmaceutical compositions containing them
FR2593809B1 (fr) 1986-01-31 1988-07-22 Lafon Labor Benzhydrylsulfinylacetamide, procede de preparation et utilisation en therapeutique
US20030187023A1 (en) * 2000-07-17 2003-10-02 Keiji Kubo Sulfone derivatives, process for their production and use thereof
WO2002010125A1 (en) 2000-07-27 2002-02-07 Teva Pharmaceutical Industries Ltd. Crystalline and pure modafinil, and process of preparing the same
IL143106A (en) 2001-05-13 2005-11-20 Chemagis Ltd Process for the preparation of diphenylmethylthioacetamide
US6875893B2 (en) * 2002-05-23 2005-04-05 Cephalon, Inc. Preparations of a sulfinyl acetamide
DE10245546B3 (de) * 2002-09-30 2004-05-13 Infineon Technologies Ag Pseudostatische Speicherschaltung
JP3838972B2 (ja) * 2002-12-25 2006-10-25 Ｎｅｃエレクトロニクス株式会社 周波数検出回路及びデータ処理装置

Also Published As

Publication number Publication date
JP4351627B2 (ja) 2009-10-28
DK1506171T3 (da) 2009-01-19
KR100984571B1 (ko) 2010-09-30
US20040002547A1 (en) 2004-01-01
JP2005527623A (ja) 2005-09-15
HK1072596A1 (en) 2005-09-02
PL211695B1 (pl) 2012-06-29
NO329559B1 (no) 2010-11-15
ES2316755T3 (es) 2009-04-16
UA79790C2 (en) 2007-07-25
US20050171209A1 (en) 2005-08-04
PL373792A1 (en) 2005-09-19
KR20050016421A (ko) 2005-02-21
WO2003099774A1 (en) 2003-12-04
DE60324671D1 (de) 2008-12-24
IS7523A (is) 2004-11-09
CN100379721C (zh) 2008-04-09
EA200401551A1 (ru) 2005-04-28
NO20044916L (no) 2004-12-16
IL165095A (en) 2010-11-30
EP1506171B1 (en) 2008-11-12
US7057069B2 (en) 2006-06-06
CN1656064A (zh) 2005-08-17
EP1506171A1 (en) 2005-02-16
TWI317733B (en) 2009-12-01
CY1108747T1 (el) 2014-04-09
MY129141A (en) 2007-03-30
IS2650B (is) 2010-08-15
PT1506171E (pt) 2009-01-02
ATE414058T1 (de) 2008-11-15
AU2003233668A1 (en) 2003-12-12
TW200406196A (en) 2004-05-01
EA007561B1 (ru) 2006-12-29
NZ536747A (en) 2006-11-30
US6875893B2 (en) 2005-04-05
BR0311242A (pt) 2005-03-15
CA2486533C (en) 2011-01-04
CA2486533A1 (en) 2003-12-04
AR039857A1 (es) 2005-03-02
IL165095A0 (en) 2005-12-18
SI1506171T1 (sl) 2009-06-30
ZA200409400B (en) 2005-12-28
EG23693A (en) 2007-05-15

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