EA200100205A1 - Способ получения 3,5-дифторанилина - Google Patents

Способ получения 3,5-дифторанилина

Info

Publication number
EA200100205A1
EA200100205A1 EA200100205A EA200100205A EA200100205A1 EA 200100205 A1 EA200100205 A1 EA 200100205A1 EA 200100205 A EA200100205 A EA 200100205A EA 200100205 A EA200100205 A EA 200100205A EA 200100205 A1 EA200100205 A1 EA 200100205A1
Authority
EA
Eurasian Patent Office
Prior art keywords
halo
diazonium salt
difluorobenzene
produce
difluoroaniline
Prior art date
Application number
EA200100205A
Other languages
English (en)
Other versions
EA006427B1 (ru
Inventor
Мартин Л. Бреммер
Уилльям Дж. Лайпа
Original Assignee
Басф Корпорейшн
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Басф Корпорейшн filed Critical Басф Корпорейшн
Publication of EA200100205A1 publication Critical patent/EA200100205A1/ru
Publication of EA006427B1 publication Critical patent/EA006427B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C245/00—Compounds containing chains of at least two nitrogen atoms with at least one nitrogen-to-nitrogen multiple bond
    • C07C245/20—Diazonium compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/35—Preparation of halogenated hydrocarbons by reactions not affecting the number of carbon or of halogen atoms in the reaction
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/04—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups
    • C07C209/06—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups by substitution of halogen atoms
    • C07C209/10—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups by substitution of halogen atoms with formation of amino groups bound to carbon atoms of six-membered aromatic rings or from amines having nitrogen atoms bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/68—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton
    • C07C209/74—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton by halogenation, hydrohalogenation, dehalogenation, or dehydrohalogenation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

В заявке описан новый способ получения 3,5-дифторанилинового соединения реакцией 2-гало-4,6-дифторанилина с диазотирующим агентом в присутствии восстановителя с получением диазониевой соли. Накопление потенциально опасной диазониевой соли предотвращают восстановлением диазониевой соли восстановителем с получением 1-гало-3,5-дифторбензола параллельно этой реакции диазотирования. Далее 1-гало-3,5-дифторбензол аминируют.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200100205A 1998-08-14 1999-08-07 Способ получения 3, 5-дифторанилина EA006427B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/134,620 US5977412A (en) 1998-08-14 1998-08-14 Process for preparing 3,5-difluoroaniline
PCT/EP1999/005729 WO2000009474A1 (en) 1998-08-14 1999-08-07 Process for preparing 3,5-difluoroaniline

Publications (2)

Publication Number Publication Date
EA200100205A1 true EA200100205A1 (ru) 2001-08-27
EA006427B1 EA006427B1 (ru) 2005-12-29

Family

ID=22464182

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200100205A EA006427B1 (ru) 1998-08-14 1999-08-07 Способ получения 3, 5-дифторанилина

Country Status (16)

Country Link
US (1) US5977412A (ru)
EP (1) EP1104399B1 (ru)
JP (1) JP4377065B2 (ru)
KR (1) KR100615505B1 (ru)
CN (1) CN1217916C (ru)
AR (1) AR020193A1 (ru)
AT (1) ATE241588T1 (ru)
AU (1) AU764560B2 (ru)
BR (1) BR9913027B1 (ru)
CA (1) CA2340442C (ru)
CZ (1) CZ301624B6 (ru)
DE (1) DE69908374T2 (ru)
EA (1) EA006427B1 (ru)
HU (1) HU225985B1 (ru)
IL (1) IL141048A0 (ru)
WO (1) WO2000009474A1 (ru)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103601613B (zh) * 2013-11-19 2015-07-08 浙江林江化工股份有限公司 一种3,4,5-三氟溴苯的制备方法
CN105348140A (zh) * 2015-12-18 2016-02-24 武汉武药制药有限公司 一种盐酸苯肼的合成方法
CN105949067A (zh) * 2016-05-06 2016-09-21 蚌埠中实化学技术有限公司 一种3,5-二氟苯胺的制备方法
CN108250051A (zh) * 2018-01-12 2018-07-06 浙江鼎龙科技有限公司 2,3-二氟苯乙醚的制备方法
CN112028736A (zh) * 2020-09-10 2020-12-04 内蒙古永太化学有限公司 一种3,5-二氯-4-氟溴苯化合物的制备方法
CN112110790B (zh) * 2020-09-28 2023-06-23 台州臻挚生物科技有限公司 一种3,5-二卤三氟甲苯及3`-氯-5`-(三氟甲基)苯基三氟乙酮的制备方法
CN112174770A (zh) * 2020-10-30 2021-01-05 德兴市德邦化工有限公司 一种3,4,5-三氟溴苯的生产工艺

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2241951A (en) * 1990-03-16 1991-09-18 Isc Chemicals Ltd Chloro-difluorobenzenes and diazonium fluoborates
EP0460639B1 (en) * 1990-06-06 1995-12-27 SDS Biotech K.K. Process for producing 3,5-difluoroaniline and derivative thereof
JPH0565250A (ja) * 1991-01-28 1993-03-19 Ishihara Sangyo Kaisha Ltd ３，５−ジフルオロアニリンの製造方法
US5204366A (en) * 1991-06-10 1993-04-20 American Cyanamid Company 2,5-dioxo-3-pyrroline-1-acetanilide fungicidal agents, compositions and method for use thereof
US5294742A (en) * 1992-03-21 1994-03-15 Hoechst Atkiengesellschaft Process for preparing 3,5-difluoroaniline
US5157169A (en) * 1992-03-26 1992-10-20 Mallinckrodt Specialty Chemicals Company Preparation of 3-halo-halobenzenes and 1-halo-3,5-dihalobenzenes
US5508892A (en) * 1993-06-22 1996-04-16 H Space Technologies, Inc. Light processing apparatus for creating visual effects
EP0667337B1 (de) * 1994-02-11 1998-01-21 Clariant GmbH Verfahren zur Herstellung von Fluoranilinen
FR2722785B1 (fr) * 1994-07-20 1996-10-25 Rhone Poulenc Chimie 1procede pour l'obtention de derives2substitue(s) en position meta.
DE19720341C1 (de) * 1997-05-15 1998-08-27 Clariant Gmbh Verfahren zur Herstellung von 3,5-Difluoranilin

Also Published As

Publication number Publication date
HUP0201110A2 (hu) 2002-07-29
JP4377065B2 (ja) 2009-12-02
AR020193A1 (es) 2002-05-02
WO2000009474A1 (en) 2000-02-24
KR20010072450A (ko) 2001-07-31
ATE241588T1 (de) 2003-06-15
BR9913027B1 (pt) 2009-08-11
CZ2001560A3 (en) 2001-06-13
CN1217916C (zh) 2005-09-07
EA006427B1 (ru) 2005-12-29
CA2340442A1 (en) 2000-02-24
BR9913027A (pt) 2001-05-08
DE69908374T2 (de) 2003-11-27
JP2002522522A (ja) 2002-07-23
CZ301624B6 (cs) 2010-05-05
IL141048A0 (en) 2002-02-10
DE69908374D1 (de) 2003-07-03
CN1312793A (zh) 2001-09-12
US5977412A (en) 1999-11-02
EP1104399A1 (en) 2001-06-06
HU225985B1 (en) 2008-02-28
EP1104399B1 (en) 2003-05-28
KR100615505B1 (ko) 2006-08-25
AU764560B2 (en) 2003-08-21
AU5731499A (en) 2000-03-06
HUP0201110A3 (en) 2004-04-28
CA2340442C (en) 2006-03-14

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ KG MD TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): BY KZ RU