EA200300079A1 - Кристаллический терапевтический агент - Google Patents

Кристаллический терапевтический агент

Info

Publication number
EA200300079A1
EA200300079A1 EA200300079A EA200300079A EA200300079A1 EA 200300079 A1 EA200300079 A1 EA 200300079A1 EA 200300079 A EA200300079 A EA 200300079A EA 200300079 A EA200300079 A EA 200300079A EA 200300079 A1 EA200300079 A1 EA 200300079A1
Authority
EA
Eurasian Patent Office
Prior art keywords
therapeutic agent
crystalline therapeutic
crystalline
pyridylsulfonyl
ethylpiperazine
Prior art date
Application number
EA200300079A
Other languages
English (en)
Other versions
EA004681B1 (ru
Inventor
Лоренс Джеймс Харрис
Ричард Энтони Стори
Альберт Шо Вуд
Original Assignee
Пфайзер Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0018656A external-priority patent/GB0018656D0/en
Priority claimed from GB0106464A external-priority patent/GB0106464D0/en
Application filed by Пфайзер Инк. filed Critical Пфайзер Инк.
Publication of EA200300079A1 publication Critical patent/EA200300079A1/ru
Publication of EA004681B1 publication Critical patent/EA004681B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

Полиморф 1-{6-этокси-5-[3-этил-6,7-дигидро-2-(2-метоксиэтил)-7-оксо-2H-пиразоло[4,3-d]пиримидин-5-ил]-3-пиридилсульфонил}-4-этилпиперазина.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200300079A 2000-07-28 2001-07-18 Кристаллический терапевтический агент EA004681B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0018656A GB0018656D0 (en) 2000-07-28 2000-07-28 Pharmaceutically active compounds
GB0106464A GB0106464D0 (en) 2001-03-15 2001-03-15 Crystalline therapeutic agent
PCT/IB2001/001280 WO2002010171A1 (en) 2000-07-28 2001-07-18 Crystalline therapeutic agent

Publications (2)

Publication Number Publication Date
EA200300079A1 true EA200300079A1 (ru) 2003-06-26
EA004681B1 EA004681B1 (ru) 2004-06-24

Family

ID=26244756

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200300079A EA004681B1 (ru) 2000-07-28 2001-07-18 Кристаллический терапевтический агент

Country Status (46)

Country Link
EP (1) EP1305314B1 (ru)
JP (1) JP2004505087A (ru)
KR (1) KR100457937B1 (ru)
CN (1) CN1207297C (ru)
AP (1) AP1400A (ru)
AR (1) AR032628A1 (ru)
AT (1) ATE286901T1 (ru)
AU (2) AU7269001A (ru)
BG (1) BG107266A (ru)
BR (1) BR0112734A (ru)
CA (1) CA2417264C (ru)
CZ (1) CZ2003126A3 (ru)
DE (1) DE60108398T2 (ru)
DO (1) DOP2001000217A (ru)
DZ (1) DZ3364A1 (ru)
EA (1) EA004681B1 (ru)
EC (1) ECSP034454A (ru)
EE (1) EE200300045A (ru)
ES (1) ES2231521T3 (ru)
GE (1) GEP20053494B (ru)
HK (1) HK1055954A1 (ru)
HR (1) HRP20030061A2 (ru)
HU (1) HUP0302982A3 (ru)
IL (1) IL153226A0 (ru)
IN (1) IN2002MU01649A (ru)
IS (1) IS6626A (ru)
MA (1) MA26931A1 (ru)
MX (1) MX233602B (ru)
MY (1) MY117831A (ru)
NO (1) NO324220B1 (ru)
NZ (1) NZ523226A (ru)
OA (1) OA12337A (ru)
PA (1) PA8523501A1 (ru)
PE (1) PE20020277A1 (ru)
PH (1) PH12001001922B1 (ru)
PL (1) PL365133A1 (ru)
PT (1) PT1305314E (ru)
SK (1) SK572003A3 (ru)
SV (1) SV2001000570A (ru)
TN (1) TNSN01112A1 (ru)
TW (1) TWI285643B (ru)
UA (1) UA72631C2 (ru)
UY (1) UY26854A1 (ru)
WO (1) WO2002010171A1 (ru)
YU (1) YU4703A (ru)
ZA (1) ZA200301457B (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004072079A1 (en) * 2003-02-11 2004-08-26 Pfizer Limited Hydrated and anhydrous sildenafil hemi-citrate compound
RS20050810A (en) 2003-04-29 2007-08-03 Pfizer Inc., 5,7-diaminopyrazolo(4,3-d)pyrimidines useful in the treatment of hypertension
US7572799B2 (en) 2003-11-24 2009-08-11 Pfizer Inc Pyrazolo[4,3-d]pyrimidines as Phosphodiesterase Inhibitors
WO2005097799A1 (en) 2004-04-07 2005-10-20 Pfizer Limited Pyrazolo`4,3-d! pyrimidines
AU2006245416B2 (en) 2005-05-12 2012-02-23 Pfizer Inc. Anhydrous crystalline forms of N-[1-(2-ethoxyethyl)-5-(N-ethyl-N-methylamino)-7-(4-methylpyridin-2-yl-amino)-1H-pyrazolo[4,3-d]pyrimidine-3-carbonyl]methanesulfonamide

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3721077B2 (ja) * 1998-04-20 2005-11-30 ファイザー・インク 性的不全を治療するためのピラゾロピリミジノンｃＧＭＰＰＤＥ５阻害剤
TWI265925B (en) * 1999-10-11 2006-11-11 Pfizer Pyrazolo[4,3-d]pyrimidin-7-ones useful in inhibiting type 5 cyclic guanosine 3',5'-monophosphate phosphodiesterases(cGMP PDE5), process and intermediates for their preparation, their uses and composition comprising them

Also Published As

Publication number Publication date
NO20030416D0 (no) 2003-01-27
ATE286901T1 (de) 2005-01-15
WO2002010171A1 (en) 2002-02-07
AP2001002234A0 (en) 2001-09-30
MX233602B (es) 2006-01-10
KR100457937B1 (ko) 2004-11-20
UY26854A1 (es) 2002-02-28
YU4703A (sh) 2006-01-16
BR0112734A (pt) 2004-08-10
CN1444585A (zh) 2003-09-24
DZ3364A1 (fr) 2002-02-07
DE60108398D1 (de) 2005-02-17
ZA200301457B (en) 2004-04-28
IL153226A0 (en) 2003-07-06
DE60108398T2 (de) 2005-12-22
EP1305314B1 (en) 2005-01-12
AR032628A1 (es) 2003-11-19
NO20030416L (no) 2003-02-05
GEP20053494B (en) 2005-04-25
MXPA03000856A (es) 2003-06-06
AU7269001A (en) 2002-02-13
ECSP034454A (es) 2003-03-10
TWI285643B (en) 2007-08-21
MY117831A (en) 2004-08-30
JP2004505087A (ja) 2004-02-19
IN2002MU01649A (ru) 2004-12-11
HUP0302982A3 (en) 2005-01-28
CA2417264C (en) 2007-06-12
HRP20030061A2 (en) 2003-04-30
CN1207297C (zh) 2005-06-22
DOP2001000217A (es) 2002-10-30
PT1305314E (pt) 2005-04-29
EA004681B1 (ru) 2004-06-24
SK572003A3 (en) 2004-05-04
CZ2003126A3 (cs) 2004-02-18
PH12001001922B1 (en) 2006-11-21
PL365133A1 (en) 2004-12-27
PA8523501A1 (es) 2002-10-24
TNSN01112A1 (fr) 2005-11-10
AP1400A (en) 2005-04-28
ES2231521T3 (es) 2005-05-16
PE20020277A1 (es) 2002-05-11
UA72631C2 (ru) 2005-03-15
EP1305314A1 (en) 2003-05-02
MA26931A1 (fr) 2004-12-20
HUP0302982A2 (hu) 2003-12-29
NZ523226A (en) 2003-07-25
EE200300045A (et) 2004-12-15
CA2417264A1 (en) 2002-02-07
KR20030016430A (ko) 2003-02-26
NO324220B1 (no) 2007-09-10
BG107266A (bg) 2003-07-31
OA12337A (en) 2006-05-15
AU2001272690B2 (en) 2005-12-08
SV2001000570A (es) 2002-09-03
HK1055954A1 (en) 2004-01-30
IS6626A (is) 2002-11-18

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): KZ

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KG MD TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): RU