EA026990B1 - Антитела, связывающиеся с человеческой клеткой dec-205 - Google Patents

Антитела, связывающиеся с человеческой клеткой dec-205 Download PDF

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Publication number
EA026990B1
EA026990B1 EA201000770A EA201000770A EA026990B1 EA 026990 B1 EA026990 B1 EA 026990B1 EA 201000770 A EA201000770 A EA 201000770A EA 201000770 A EA201000770 A EA 201000770A EA 026990 B1 EA026990 B1 EA 026990B1
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EA
Eurasian Patent Office
Prior art keywords
sequence
variable region
chain containing
antigen
heavy chain
Prior art date
Application number
EA201000770A
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English (en)
Russian (ru)
Other versions
EA201000770A1 (ru
Inventor
Тибор Келер
Личжэнь Хе
Венки Рамакришна
Лаура А. Витейл
Original Assignee
Селлдекс Терапьютикс Инк.
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40257038&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA026990(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Селлдекс Терапьютикс Инк. filed Critical Селлдекс Терапьютикс Инк.
Publication of EA201000770A1 publication Critical patent/EA201000770A1/ru
Publication of EA026990B1 publication Critical patent/EA026990B1/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2851—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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    • A—HUMAN NECESSITIES
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    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77—Internalization into the cell
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • AIDS & HIV (AREA)
  • Reproductive Health (AREA)
EA201000770A 2007-11-07 2008-11-07 Антитела, связывающиеся с человеческой клеткой dec-205 EA026990B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US225307P 2007-11-07 2007-11-07
US19155108P 2008-09-10 2008-09-10
PCT/US2008/082745 WO2009061996A2 (en) 2007-11-07 2008-11-07 Antibodies that bind human dendritic and epithelial cell 205 (dec-205)

Publications (2)

Publication Number Publication Date
EA201000770A1 EA201000770A1 (ru) 2010-12-30
EA026990B1 true EA026990B1 (ru) 2017-06-30

Family

ID=40257038

Family Applications (2)

Application Number Title Priority Date Filing Date
EA201000770A EA026990B1 (ru) 2007-11-07 2008-11-07 Антитела, связывающиеся с человеческой клеткой dec-205
EA201692127A EA201692127A1 (ru) 2007-11-07 2008-11-07 Антитела, связывающиеся с человеческим dec-205

Family Applications After (1)

Application Number Title Priority Date Filing Date
EA201692127A EA201692127A1 (ru) 2007-11-07 2008-11-07 Антитела, связывающиеся с человеческим dec-205

Country Status (17)

Country Link
US (4) US8236318B2 (enExample)
EP (2) EP2224954B1 (enExample)
JP (3) JP5701606B2 (enExample)
KR (2) KR101624751B1 (enExample)
CN (1) CN101888856B (enExample)
AU (1) AU2008323848B2 (enExample)
BR (1) BRPI0820270A2 (enExample)
CA (1) CA2704583A1 (enExample)
DK (1) DK2224954T3 (enExample)
EA (2) EA026990B1 (enExample)
ES (1) ES2445755T3 (enExample)
IL (1) IL205393A (enExample)
MX (1) MX2010005022A (enExample)
NZ (2) NZ585556A (enExample)
SG (2) SG187482A1 (enExample)
WO (1) WO2009061996A2 (enExample)
ZA (1) ZA201003101B (enExample)

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WO2006069198A1 (en) 2004-12-22 2006-06-29 Cleveland Clinic Foundation Flagellin related polypeptides and uses thereof
CA3058450A1 (en) * 2006-10-19 2008-04-24 Baylor College Of Medicine Generating an immune response by inducing cd40 and pattern recognition receptors
KR20090114430A (ko) * 2007-02-02 2009-11-03 베일러 리서치 인스티튜트 항원-제시 세포 상에서 발현된 ｄｃｉｒ에 대한 항원 표적화에 기초한 백신
WO2008104803A2 (en) * 2007-02-26 2008-09-04 Oxford Genome Sciences (Uk) Limited Proteins
SG187482A1 (en) 2007-11-07 2013-02-28 Celldex Therapeutics Inc Antibodies that bind human dendritic and epithelial cell 205 (dec-205)
US8324163B2 (en) 2008-08-01 2012-12-04 Cleveland Biolabs, Inc. Methods for treating reperfusion injuries using flagellin
WO2010033949A1 (en) 2008-09-22 2010-03-25 Baylor College Of Medicine Methods and compositions for generating an immune response by inducing cd40 and pattern recognition receptor adapters
SG178930A1 (en) 2009-08-29 2012-04-27 Abbott Lab Therapeutic dll4 binding proteins
AU2010291939B2 (en) 2009-09-14 2012-11-15 Baylor Research Institute Vaccines directed to Langerhans cells
AU2010303304A1 (en) * 2009-10-08 2012-05-17 President And Fellows Of Harvard College Methods and compositions for amelioration of autoimmune disease using fusion proteins of anti-dendritic cell receptor antibody to peptide sequences
EP3018146A1 (en) * 2009-11-18 2016-05-11 MannKind Corporation Monoclonal antibodies and diagnostic uses thereof
RU2605928C2 (ru) * 2010-03-02 2016-12-27 Эббви Инк. Терапевтические dll4-связывающие белки
ES2608475T3 (es) 2010-04-13 2017-04-11 Celldex Therapeutics, Inc. Anticuerpos que se unen a cd27 humana y usos de los mismos
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US9089520B2 (en) 2010-05-21 2015-07-28 Baylor College Of Medicine Methods for inducing selective apoptosis
DE102010039019B4 (de) 2010-08-06 2014-08-07 Technische Universität Dresden Antikörper gegen 6-sulfo LacNAc positive humane dendritische Zellen und deren Verwendung
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US11484627B2 (en) 2010-10-20 2022-11-01 206 Ortho, Inc. Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications
US11207109B2 (en) 2010-10-20 2021-12-28 206 Ortho, Inc. Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications
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MX361355B (es) * 2011-01-10 2018-12-04 Cleveland Biolabs Inc Uso del agonista del receptor tipo toll para el tratamiento del cáncer.
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AR087380A1 (es) * 2011-07-27 2014-03-19 Baylor Res Inst Vacunas de celulas dendriticas (cd) para la terapia del cancer de pancreas
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CN103044552B (zh) * 2012-12-11 2019-01-29 中国医学科学院病原生物学研究所 人源化的抗树突状细胞表面dec-205分子的单克隆抗体
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US20130101593A1 (en) 2013-04-25
EP2570137A3 (en) 2013-08-21
EA201692127A1 (ru) 2017-08-31
JP2017014218A (ja) 2017-01-19
CN101888856A (zh) 2010-11-17
WO2009061996A2 (en) 2009-05-14
CA2704583A1 (en) 2009-05-14
KR101811965B1 (ko) 2017-12-22
SG187482A1 (en) 2013-02-28
US20100098704A1 (en) 2010-04-22
NZ585556A (en) 2012-07-27
MX2010005022A (es) 2010-06-02
BRPI0820270A2 (pt) 2015-06-16
SG10201605208QA (en) 2016-08-30
US9624300B2 (en) 2017-04-18
WO2009061996A3 (en) 2009-09-03
AU2008323848B2 (en) 2014-09-25
KR20100100857A (ko) 2010-09-15
EP2224954B1 (en) 2014-01-08
HK1146898A1 (en) 2011-07-22
KR20160017128A (ko) 2016-02-15
KR101624751B1 (ko) 2016-05-27
JP5701606B2 (ja) 2015-04-15
US8586720B2 (en) 2013-11-19
JP2015083010A (ja) 2015-04-30

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