AU2008323848B2 - Antibodies that bind human dendritic and epithelial cell 205 (DEC-205) - Google Patents

Antibodies that bind human dendritic and epithelial cell 205 (DEC-205) Download PDF

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Publication number
AU2008323848B2
AU2008323848B2 AU2008323848A AU2008323848A AU2008323848B2 AU 2008323848 B2 AU2008323848 B2 AU 2008323848B2 AU 2008323848 A AU2008323848 A AU 2008323848A AU 2008323848 A AU2008323848 A AU 2008323848A AU 2008323848 B2 AU2008323848 B2 AU 2008323848B2
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Australia
Prior art keywords
seq
chain variable
variable region
antibody
antigen
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Ceased
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AU2008323848A
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AU2008323848A1 (en
Inventor
Lizhen He
Tibor Keler
Venky Ramakrishna
Laura A. Vitale
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Celldex Therapeutics Inc
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Celldex Therapeutics Inc
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Application filed by Celldex Therapeutics Inc filed Critical Celldex Therapeutics Inc
Publication of AU2008323848A1 publication Critical patent/AU2008323848A1/en
Priority to AU2013201417A priority Critical patent/AU2013201417B2/en
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Publication of AU2008323848B2 publication Critical patent/AU2008323848B2/en
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2851Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77Internalization into the cell
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

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  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Pulmonology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Emergency Medicine (AREA)
AU2008323848A 2007-11-07 2008-11-07 Antibodies that bind human dendritic and epithelial cell 205 (DEC-205) Ceased AU2008323848B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2013201417A AU2013201417B2 (en) 2007-11-07 2013-03-12 Antibodies that bind human dendritic and epithelial cell 205 (DEC-205)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US225307P 2007-11-07 2007-11-07
US61/002,253 2007-11-07
US19155108P 2008-09-10 2008-09-10
US61/191,551 2008-09-10
PCT/US2008/082745 WO2009061996A2 (en) 2007-11-07 2008-11-07 Antibodies that bind human dendritic and epithelial cell 205 (dec-205)

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2013201417A Division AU2013201417B2 (en) 2007-11-07 2013-03-12 Antibodies that bind human dendritic and epithelial cell 205 (DEC-205)

Publications (2)

Publication Number Publication Date
AU2008323848A1 AU2008323848A1 (en) 2009-05-14
AU2008323848B2 true AU2008323848B2 (en) 2014-09-25

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ID=40257038

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2008323848A Ceased AU2008323848B2 (en) 2007-11-07 2008-11-07 Antibodies that bind human dendritic and epithelial cell 205 (DEC-205)

Country Status (17)

Country Link
US (4) US8236318B2 (enExample)
EP (2) EP2224954B1 (enExample)
JP (3) JP5701606B2 (enExample)
KR (2) KR101811965B1 (enExample)
CN (1) CN101888856B (enExample)
AU (1) AU2008323848B2 (enExample)
BR (1) BRPI0820270A2 (enExample)
CA (1) CA2704583A1 (enExample)
DK (1) DK2224954T3 (enExample)
EA (2) EA026990B1 (enExample)
ES (1) ES2445755T3 (enExample)
IL (1) IL205393A (enExample)
MX (1) MX2010005022A (enExample)
NZ (2) NZ585556A (enExample)
SG (2) SG187482A1 (enExample)
WO (1) WO2009061996A2 (enExample)
ZA (1) ZA201003101B (enExample)

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JP6041444B2 (ja) 2011-01-10 2016-12-07 クリーブランド バイオラブズ,インコーポレイテッド 癌を治療するためのToll様受容体アゴニストの使用
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