AU2008323848B2 - Antibodies that bind human dendritic and epithelial cell 205 (DEC-205) - Google Patents

Antibodies that bind human dendritic and epithelial cell 205 (DEC-205) Download PDF

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Publication number
AU2008323848B2
AU2008323848B2 AU2008323848A AU2008323848A AU2008323848B2 AU 2008323848 B2 AU2008323848 B2 AU 2008323848B2 AU 2008323848 A AU2008323848 A AU 2008323848A AU 2008323848 A AU2008323848 A AU 2008323848A AU 2008323848 B2 AU2008323848 B2 AU 2008323848B2
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Australia
Prior art keywords
seq
chain variable
variable region
antibody
antigen
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Ceased
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AU2008323848A
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AU2008323848A1 (en
Inventor
Lizhen He
Tibor Keler
Venky Ramakrishna
Laura A. Vitale
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Celldex Therapeutics Inc
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Celldex Therapeutics Inc
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Application filed by Celldex Therapeutics Inc filed Critical Celldex Therapeutics Inc
Publication of AU2008323848A1 publication Critical patent/AU2008323848A1/en
Priority to AU2013201417A priority Critical patent/AU2013201417B2/en
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2851—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77—Internalization into the cell
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Reproductive Health (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
AU2008323848A 2007-11-07 2008-11-07 Antibodies that bind human dendritic and epithelial cell 205 (DEC-205) Ceased AU2008323848B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2013201417A AU2013201417B2 (en) 2007-11-07 2013-03-12 Antibodies that bind human dendritic and epithelial cell 205 (DEC-205)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US225307P 2007-11-07 2007-11-07
US61/002,253 2007-11-07
US19155108P 2008-09-10 2008-09-10
US61/191,551 2008-09-10
PCT/US2008/082745 WO2009061996A2 (en) 2007-11-07 2008-11-07 Antibodies that bind human dendritic and epithelial cell 205 (dec-205)

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2013201417A Division AU2013201417B2 (en) 2007-11-07 2013-03-12 Antibodies that bind human dendritic and epithelial cell 205 (DEC-205)

Publications (2)

Publication Number Publication Date
AU2008323848A1 AU2008323848A1 (en) 2009-05-14
AU2008323848B2 true AU2008323848B2 (en) 2014-09-25

Family

ID=40257038

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2008323848A Ceased AU2008323848B2 (en) 2007-11-07 2008-11-07 Antibodies that bind human dendritic and epithelial cell 205 (DEC-205)

Country Status (17)

Country Link
US (4) US8236318B2 (enExample)
EP (2) EP2224954B1 (enExample)
JP (3) JP5701606B2 (enExample)
KR (2) KR101811965B1 (enExample)
CN (1) CN101888856B (enExample)
AU (1) AU2008323848B2 (enExample)
BR (1) BRPI0820270A2 (enExample)
CA (1) CA2704583A1 (enExample)
DK (1) DK2224954T3 (enExample)
EA (2) EA201692127A1 (enExample)
ES (1) ES2445755T3 (enExample)
IL (1) IL205393A (enExample)
MX (1) MX2010005022A (enExample)
NZ (2) NZ599777A (enExample)
SG (2) SG10201605208QA (enExample)
WO (1) WO2009061996A2 (enExample)
ZA (1) ZA201003101B (enExample)

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EP2460534A1 (en) 2004-12-22 2012-06-06 Cleveland Clinic Foundation Flagellin related polypeptides and uses thereof
CA3058450A1 (en) * 2006-10-19 2008-04-24 Baylor College Of Medicine Generating an immune response by inducing cd40 and pattern recognition receptors
KR20090114430A (ko) * 2007-02-02 2009-11-03 베일러 리서치 인스티튜트 항원-제시 세포 상에서 발현된 ｄｃｉｒ에 대한 항원 표적화에 기초한 백신
WO2008104803A2 (en) * 2007-02-26 2008-09-04 Oxford Genome Sciences (Uk) Limited Proteins
CN101888856B (zh) 2007-11-07 2014-08-27 塞尔德克斯医疗公司 结合人树突和上皮细胞205(dec-205)的抗体
CN102170911B (zh) 2008-08-01 2014-07-02 克里夫兰生物实验室公司 用于治疗再灌注损伤的方法
CA2738031C (en) * 2008-09-22 2022-11-29 Baylor College Of Medicine Methods and compositions for generating an immune response by inducing cd40 and pattern recognition receptor adapters
BR112012004546A8 (pt) 2009-08-29 2017-12-05 Abbott Lab Terapêutica por proteínas ligantes dll4-ligantes
EP2477655A4 (en) 2009-09-14 2014-02-12 Baylor Res Inst VACCINES TREATED ON LANGERHANS CELLS
AU2010303304A1 (en) * 2009-10-08 2012-05-17 President And Fellows Of Harvard College Methods and compositions for amelioration of autoimmune disease using fusion proteins of anti-dendritic cell receptor antibody to peptide sequences
CN102869682B (zh) 2009-11-18 2016-10-19 曼康公司 单克隆抗体及其诊断用途
KR101853278B1 (ko) * 2010-03-02 2018-05-02 애브비 인코포레이티드 치료학적 ｄｌｌ４ 결합 단백질
EA201690310A1 (ru) 2010-04-13 2016-12-30 Селлдекс Терапьютикс Инк. Антитела, связывающие cd27 человека, и их применение
US20110287038A1 (en) * 2010-04-16 2011-11-24 Kevin Slawin Method for treating solid tumors
US9089520B2 (en) 2010-05-21 2015-07-28 Baylor College Of Medicine Methods for inducing selective apoptosis
DE102010039019B4 (de) 2010-08-06 2014-08-07 Technische Universität Dresden Antikörper gegen 6-sulfo LacNAc positive humane dendritische Zellen und deren Verwendung
KR20130108295A (ko) * 2010-08-13 2013-10-02 베일러 리서치 인스티튜트 항원-제시 세포에 항체에 대한 보조제를 직접 표적화함을 기초로 하는 신규 백신 보조제
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US11291483B2 (en) 2010-10-20 2022-04-05 206 Ortho, Inc. Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants
US11207109B2 (en) 2010-10-20 2021-12-28 206 Ortho, Inc. Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications
US11484627B2 (en) 2010-10-20 2022-11-01 206 Ortho, Inc. Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications
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CN101888856A (zh) 2010-11-17
ZA201003101B (en) 2014-10-29
NZ599777A (en) 2013-09-27
EA201692127A1 (ru) 2017-08-31
CA2704583A1 (en) 2009-05-14
EP2570137A2 (en) 2013-03-20
KR20160017128A (ko) 2016-02-15
US9624300B2 (en) 2017-04-18
HK1146898A1 (en) 2011-07-22
DK2224954T3 (en) 2014-03-03
US8586720B2 (en) 2013-11-19
US20130101593A1 (en) 2013-04-25
BRPI0820270A2 (pt) 2015-06-16
US20120309031A1 (en) 2012-12-06
EA026990B1 (ru) 2017-06-30
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JP2015083010A (ja) 2015-04-30
JP6067667B2 (ja) 2017-01-25
KR20100100857A (ko) 2010-09-15
US8362214B2 (en) 2013-01-29
MX2010005022A (es) 2010-06-02
AU2008323848A1 (en) 2009-05-14
SG187482A1 (en) 2013-02-28
WO2009061996A2 (en) 2009-05-14
US20100098704A1 (en) 2010-04-22
JP2017014218A (ja) 2017-01-19
KR101811965B1 (ko) 2017-12-22
IL205393A (en) 2015-04-30
KR101624751B1 (ko) 2016-05-27
EP2570137A3 (en) 2013-08-21
JP5701606B2 (ja) 2015-04-15
US8236318B2 (en) 2012-08-07
JP2011503014A (ja) 2011-01-27
US20090175880A1 (en) 2009-07-09
NZ585556A (en) 2012-07-27
EA201000770A1 (ru) 2010-12-30
EP2224954B1 (en) 2014-01-08
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CN101888856B (zh) 2014-08-27

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