BRPI0820270A2 - Anticorpo monoclonal, vetor de expressão, célula, conjugado molecular, composição, uso da composição, método para detectar a presença ou ausência de dec-205 em uma amostra biológica, e, uso de um conjugado molecular. - Google Patents
Anticorpo monoclonal, vetor de expressão, célula, conjugado molecular, composição, uso da composição, método para detectar a presença ou ausência de dec-205 em uma amostra biológica, e, uso de um conjugado molecular.Info
- Publication number
- BRPI0820270A2 BRPI0820270A2 BRPI0820270-2A BRPI0820270A BRPI0820270A2 BR PI0820270 A2 BRPI0820270 A2 BR PI0820270A2 BR PI0820270 A BRPI0820270 A BR PI0820270A BR PI0820270 A2 BRPI0820270 A2 BR PI0820270A2
- Authority
- BR
- Brazil
- Prior art keywords
- composition
- molecular conjugate
- dec
- absence
- cell
- Prior art date
Links
- 239000012472 biological sample Substances 0.000 title 1
- 239000013604 expression vector Substances 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2851—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/77—Internalization into the cell
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- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
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- Orthopedic Medicine & Surgery (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Transplantation (AREA)
- Cardiology (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US225307P | 2007-11-07 | 2007-11-07 | |
| US19155108P | 2008-09-10 | 2008-09-10 | |
| PCT/US2008/082745 WO2009061996A2 (en) | 2007-11-07 | 2008-11-07 | Antibodies that bind human dendritic and epithelial cell 205 (dec-205) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0820270A2 true BRPI0820270A2 (pt) | 2015-06-16 |
Family
ID=40257038
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0820270-2A BRPI0820270A2 (pt) | 2007-11-07 | 2008-11-07 | Anticorpo monoclonal, vetor de expressão, célula, conjugado molecular, composição, uso da composição, método para detectar a presença ou ausência de dec-205 em uma amostra biológica, e, uso de um conjugado molecular. |
Country Status (17)
| Country | Link |
|---|---|
| US (4) | US8236318B2 (enExample) |
| EP (2) | EP2570137A3 (enExample) |
| JP (3) | JP5701606B2 (enExample) |
| KR (2) | KR101811965B1 (enExample) |
| CN (1) | CN101888856B (enExample) |
| AU (1) | AU2008323848B2 (enExample) |
| BR (1) | BRPI0820270A2 (enExample) |
| CA (1) | CA2704583A1 (enExample) |
| DK (1) | DK2224954T3 (enExample) |
| EA (2) | EA201692127A1 (enExample) |
| ES (1) | ES2445755T3 (enExample) |
| IL (1) | IL205393A (enExample) |
| MX (1) | MX2010005022A (enExample) |
| NZ (2) | NZ599777A (enExample) |
| SG (2) | SG10201605208QA (enExample) |
| WO (1) | WO2009061996A2 (enExample) |
| ZA (1) | ZA201003101B (enExample) |
Families Citing this family (73)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1641927B1 (en) | 2003-02-18 | 2015-07-08 | Baylor College of Medicine | Induced activation in dendritic cells |
| EP2460534A1 (en) | 2004-12-22 | 2012-06-06 | Cleveland Clinic Foundation | Flagellin related polypeptides and uses thereof |
| US8691210B2 (en) * | 2006-10-19 | 2014-04-08 | David M Spencer | Methods and compositions for generating an immune response by inducing CD40 and pattern recognition receptors and adaptors thereof |
| CA2715044A1 (en) * | 2007-02-02 | 2008-08-14 | Baylor Research Institute | Vaccines based on targeting antigen to dcir expressed an antigen-presenting cells |
| WO2008104803A2 (en) | 2007-02-26 | 2008-09-04 | Oxford Genome Sciences (Uk) Limited | Proteins |
| EA201692127A1 (ru) | 2007-11-07 | 2017-08-31 | Селлдекс Терапьютикс Инк. | Антитела, связывающиеся с человеческим dec-205 |
| EP2320948B1 (en) | 2008-08-01 | 2013-03-06 | Cleveland Biolabs, Inc. | Methods for treating reperfusion injuries |
| WO2010033949A1 (en) | 2008-09-22 | 2010-03-25 | Baylor College Of Medicine | Methods and compositions for generating an immune response by inducing cd40 and pattern recognition receptor adapters |
| CN105131112A (zh) | 2009-08-29 | 2015-12-09 | Abbvie公司 | 治疗用dll4结合蛋白 |
| BR112012005713A2 (pt) | 2009-09-14 | 2019-09-24 | Baylor Res Institute | vacinas direcionadas a célula langerhans. |
| CA2813494A1 (en) * | 2009-10-08 | 2011-04-14 | President And Fellows Of Harvard College | Methods and compositions for amelioration of autoimmune disease using fusion proteins of anti-dendritic cell receptor antibody to peptide sequences |
| US8846872B2 (en) | 2009-11-18 | 2014-09-30 | Mannkind Corporation | Monoclonal antibodies and diagnostic uses thereof |
| AU2011223919B2 (en) | 2010-03-02 | 2015-03-19 | Abbvie Inc. | Therapeutic DLL4 binding proteins |
| EA201690310A1 (ru) | 2010-04-13 | 2016-12-30 | Селлдекс Терапьютикс Инк. | Антитела, связывающие cd27 человека, и их применение |
| AU2011239569B2 (en) * | 2010-04-16 | 2014-07-24 | Baylor College Of Medicine | Method for treating solid tumors |
| US9089520B2 (en) | 2010-05-21 | 2015-07-28 | Baylor College Of Medicine | Methods for inducing selective apoptosis |
| DE102010039019B4 (de) | 2010-08-06 | 2014-08-07 | Technische Universität Dresden | Antikörper gegen 6-sulfo LacNAc positive humane dendritische Zellen und deren Verwendung |
| WO2012021834A1 (en) * | 2010-08-13 | 2012-02-16 | Baylor Research Institute | Novel vaccine adjuvants based on targeting adjuvants to antibodies directly to antigen-presenting cells |
| US11291483B2 (en) | 2010-10-20 | 2022-04-05 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants |
| WO2015095745A1 (en) | 2010-10-20 | 2015-06-25 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications |
| US11207109B2 (en) | 2010-10-20 | 2021-12-28 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications |
| US11484627B2 (en) | 2010-10-20 | 2022-11-01 | 206 Ortho, Inc. | Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications |
| WO2012097012A1 (en) | 2011-01-10 | 2012-07-19 | Cleveland Biolabs, Inc. | Use of toll-like receptor agonist for treating cancer |
| JP5828909B2 (ja) * | 2011-01-10 | 2015-12-09 | シーティー アトランティック リミテッド | 腫瘍関連抗原結合抗体を含む併用療法 |
| WO2013009841A1 (en) * | 2011-07-11 | 2013-01-17 | Baylor Research Institute | Subsets of antigen-presenting cells (apc's) in the human vagina and their distinct functions |
| US20130028915A1 (en) * | 2011-07-27 | 2013-01-31 | Baylor Research Institute | Dendritic cell (dc)-vaccine therapy for pancreatic cancer |
| KR102367723B1 (ko) * | 2012-03-28 | 2022-02-28 | 사노피 | 브라디키닌 b1 수용체 리간드에 대한 항체 |
| GB201220010D0 (en) * | 2012-11-07 | 2012-12-19 | Oxford Biotherapeutics Ltd | Therapeutic amd diagnostic target |
| CN103044552B (zh) * | 2012-12-11 | 2019-01-29 | 中国医学科学院病原生物学研究所 | 人源化的抗树突状细胞表面dec-205分子的单克隆抗体 |
| US9434935B2 (en) | 2013-03-10 | 2016-09-06 | Bellicum Pharmaceuticals, Inc. | Modified caspase polypeptides and uses thereof |
| WO2014151960A2 (en) | 2013-03-14 | 2014-09-25 | Bellicum Pharmaceuticals, Inc. | Methods for controlling t cell proliferation |
| US20140302037A1 (en) * | 2013-03-15 | 2014-10-09 | Amgen Inc. | BISPECIFIC-Fc MOLECULES |
| WO2014197638A2 (en) | 2013-06-05 | 2014-12-11 | Bellicum Pharmaceuticals, Inc. | Methods for inducing partial apoptosis using caspase polypeptides |
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2008
- 2008-11-07 EA EA201692127A patent/EA201692127A1/ru unknown
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2010
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2012
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2016
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