EA020470B1 - 3-аминоциклопентанкарбоксамиды в качестве модуляторов рецептора хемокина - Google Patents

3-аминоциклопентанкарбоксамиды в качестве модуляторов рецептора хемокина Download PDF

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Publication number
EA020470B1
EA020470B1 EA201170721A EA201170721A EA020470B1 EA 020470 B1 EA020470 B1 EA 020470B1 EA 201170721 A EA201170721 A EA 201170721A EA 201170721 A EA201170721 A EA 201170721A EA 020470 B1 EA020470 B1 EA 020470B1
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EA
Eurasian Patent Office
Prior art keywords
amino
trifluoromethyl
diazabicyclo
carbonyl
anhydro
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EA201170721A
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English (en)
Russian (ru)
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EA201170721A1 (ru
Inventor
Раджеш Венкатесваран Деврадж
Вей Хуанг
Роберт Оуэн Хьюгес
Дональд Джозеф Роджиер Дж.
Джон Исидро Труджилло
Стив Рональд Тёрнер
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Пфайзер Инк.
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Publication of EA201170721A1 publication Critical patent/EA201170721A1/ru
Publication of EA020470B1 publication Critical patent/EA020470B1/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
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    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

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EA201170721A 2008-11-26 2009-11-20 3-аминоциклопентанкарбоксамиды в качестве модуляторов рецептора хемокина EA020470B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11805308P 2008-11-26 2008-11-26
PCT/IB2009/055232 WO2010061329A1 (en) 2008-11-26 2009-11-20 3-aminocyclopentanecarboxamides as chemokine receptor modulators

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EA201170721A1 EA201170721A1 (ru) 2011-12-30
EA020470B1 true EA020470B1 (ru) 2014-11-28

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EA201170721A EA020470B1 (ru) 2008-11-26 2009-11-20 3-аминоциклопентанкарбоксамиды в качестве модуляторов рецептора хемокина

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US (2) US8293903B2 (OSRAM)
EP (1) EP2370442B9 (OSRAM)
JP (1) JP5108153B2 (OSRAM)
KR (1) KR101374412B1 (OSRAM)
CN (1) CN102227429B (OSRAM)
AP (1) AP3113A (OSRAM)
AU (1) AU2009321221B2 (OSRAM)
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CA (1) CA2743030C (OSRAM)
CL (1) CL2011001223A1 (OSRAM)
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DO (1) DOP2011000154A (OSRAM)
EA (1) EA020470B1 (OSRAM)
EC (1) ECSP11011081A (OSRAM)
ES (1) ES2415430T3 (OSRAM)
GE (1) GEP20146064B (OSRAM)
HR (1) HRP20130409T2 (OSRAM)
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PT2370442E (pt) * 2008-11-26 2013-06-27 Pfizer 3-aminociclopentanocarboxamidas como moduladores de receptor de quimiocina
KR101303963B1 (ko) * 2011-04-08 2013-09-05 재단법인 경기과학기술진흥원 (1ｒ,2ｒ,3ｒ)-3-아미노사이클로펜탄-1,2-디올을 포함하는 항알러지용 조성물
CA2946538A1 (en) 2014-04-04 2015-10-08 Del Mar Pharmaceuticals Use of dianhydrogalactitol and analogs or derivatives thereof to treat non-small-cell carcinoma of the lung and ovarian cancer
JP2016029038A (ja) * 2014-07-17 2016-03-03 参天製薬株式会社 加齢黄斑変性の予防または治療剤
JOP20190040A1 (ar) * 2016-09-14 2019-03-10 Novartis Ag توليفة من ناهضات fxr
TWI830733B (zh) * 2018-05-11 2024-02-01 中國大陸商迪哲（江蘇）醫藥有限公司 環戊烷化合物

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EP2370442B9 (en) 2013-09-04
SI2370442T1 (sl) 2013-06-28
EA201170721A1 (ru) 2011-12-30
CN102227429B (zh) 2014-05-28
US8293903B2 (en) 2012-10-23
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CA2743030A1 (en) 2010-06-03
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AP3113A (en) 2015-01-31
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ZA201104069B (en) 2012-02-29
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UA99978C2 (en) 2012-10-25
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ME01144B (me) 2013-03-20
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KR101374412B1 (ko) 2014-03-17
RS52810B (sr) 2013-10-31
HK1161261A1 (en) 2012-08-24
HRP20130409T2 (hr) 2013-11-22

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