EA006767B1 - Применение ингибитора il-18 для приготовления лекарственного средства для лечения и/или профилактики заболевания сердца - Google Patents
Применение ингибитора il-18 для приготовления лекарственного средства для лечения и/или профилактики заболевания сердца Download PDFInfo
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- EA006767B1 EA006767B1 EA200300844A EA200300844A EA006767B1 EA 006767 B1 EA006767 B1 EA 006767B1 EA 200300844 A EA200300844 A EA 200300844A EA 200300844 A EA200300844 A EA 200300844A EA 006767 B1 EA006767 B1 EA 006767B1
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Classifications
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
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- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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Landscapes
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- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01101959 | 2001-01-29 | ||
| PCT/EP2002/000844 WO2002060479A1 (en) | 2001-01-29 | 2002-01-28 | Use of il-18 inhibitors for the treatment and/or prevention of heart disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA200300844A1 EA200300844A1 (ru) | 2003-12-25 |
| EA006767B1 true EA006767B1 (ru) | 2006-04-28 |
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200300844A EA006767B1 (ru) | 2001-01-29 | 2002-01-28 | Применение ингибитора il-18 для приготовления лекарственного средства для лечения и/или профилактики заболевания сердца |
| EA200501549A EA010180B1 (ru) | 2001-01-29 | 2002-01-28 | Применение ингибитора il-18 для приготовления лекарственного средства для лечения и/или профилактики кардиомиопатии |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200501549A EA010180B1 (ru) | 2001-01-29 | 2002-01-28 | Применение ингибитора il-18 для приготовления лекарственного средства для лечения и/или профилактики кардиомиопатии |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US20040234523A1 (https=) |
| EP (1) | EP1355668B1 (https=) |
| JP (2) | JP4860897B2 (https=) |
| KR (1) | KR100857376B1 (https=) |
| CN (1) | CN1326562C (https=) |
| AR (1) | AR032422A1 (https=) |
| AT (1) | ATE380558T1 (https=) |
| BG (1) | BG66483B1 (https=) |
| BR (1) | BR0206819A (https=) |
| CA (1) | CA2435466C (https=) |
| CY (1) | CY1107203T1 (https=) |
| CZ (1) | CZ305653B6 (https=) |
| DE (1) | DE60224004T2 (https=) |
| DK (1) | DK1355668T3 (https=) |
| EA (2) | EA006767B1 (https=) |
| EE (1) | EE05534B1 (https=) |
| ES (1) | ES2295332T3 (https=) |
| HR (1) | HRP20030609A2 (https=) |
| HU (1) | HU229164B1 (https=) |
| IL (2) | IL157024A0 (https=) |
| ME (1) | ME00549B (https=) |
| MX (1) | MXPA03006776A (https=) |
| NO (1) | NO331083B1 (https=) |
| PL (1) | PL213568B1 (https=) |
| PT (1) | PT1355668E (https=) |
| RS (1) | RS51125B (https=) |
| SI (1) | SI1355668T1 (https=) |
| SK (1) | SK287620B6 (https=) |
| UA (1) | UA80676C2 (https=) |
| WO (1) | WO2002060479A1 (https=) |
| ZA (1) | ZA200305439B (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2399148A1 (en) | 2000-02-10 | 2001-08-16 | Abbott Laboratories | Antibodies that bind human interleukin-18 and methods of making and using |
| JP2004528010A (ja) | 2000-10-11 | 2004-09-16 | バイロン・セラピューティックス・インコーポレーテッド | 免疫モジュレーションのための核酸およびポリペプチド |
| US7718368B2 (en) | 2000-12-04 | 2010-05-18 | Viron Therapeutics Inc. | Immunomodulatory protein and useful embodiments thereof |
| US20080076708A1 (en) | 2003-05-13 | 2008-03-27 | Valter Altarocca | Active Variants of the Il-18 Binding Protein and Medical Uses Thereof |
| US7968684B2 (en) | 2003-11-12 | 2011-06-28 | Abbott Laboratories | IL-18 binding proteins |
| JP4961559B2 (ja) * | 2004-03-11 | 2012-06-27 | 友昭 星野 | インターロイキン１８阻害剤を有効成分とする疾患の予防又は治療剤 |
| AU2006254103B2 (en) | 2005-06-03 | 2012-09-06 | Ares Trading S.A. | Production of recombinant IL-18 binding protein |
| AU2006256763B2 (en) | 2005-06-10 | 2012-08-02 | Ares Trading S.A. | Process for the purification of IL-18 binding protein |
| WO2009061832A1 (en) * | 2007-11-05 | 2009-05-14 | Kci Licensing Inc. | Identification of tissue for debridement |
| US9376489B2 (en) | 2012-09-07 | 2016-06-28 | Novartis Ag | IL-18 binding molecules |
| UA125204C2 (uk) * | 2013-09-05 | 2022-02-02 | Аб2 Біо Са | Застосування il-18-зв'язувального білка (il-18bp) при запальних захворюваннях |
| US10882905B2 (en) | 2015-03-05 | 2021-01-05 | Ab2 Bio Sa | IL-18 binding protein (IL-18BP) and antibodies in inflammatory diseases |
| WO2018013509A1 (en) * | 2016-07-11 | 2018-01-18 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Compositions and methods for diagnosing and treating arrhythmias |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6204261B1 (en) * | 1995-12-20 | 2001-03-20 | Vertex Pharmaceuticals Incorporated | Inhibitors of interleukin-1β Converting enzyme inhibitors |
| US5605690A (en) * | 1989-09-05 | 1997-02-25 | Immunex Corporation | Methods of lowering active TNF-α levels in mammals using tumor necrosis factor receptor |
| NZ322197A (en) * | 1995-11-21 | 1999-02-25 | Yamanouchi Pharma Co Ltd | Pyrido[2,3-d] pyrimidine derivatives and pharmaceutical compositions thereof |
| AU738048B2 (en) * | 1996-09-12 | 2001-09-06 | Idun Pharmaceuticals, Inc. | Inhibition of apoptosis using interleukin-1beta-converting enzyme (ICE)/CED-3 family inhibitors |
| ATE346085T1 (de) * | 1996-12-06 | 2006-12-15 | Vertex Pharma | Inhibitoren des interleukin-1-beta konvertierenden enzyms |
| SK122199A3 (en) * | 1997-03-18 | 2000-12-11 | Basf Ag | Methods and compositions for modulating responsiveness to corticosteroids |
| IL121860A0 (en) * | 1997-08-14 | 1998-02-22 | Yeda Res & Dev | Interleukin-18 binding proteins their preparation and use |
| DE19743687C1 (de) * | 1997-10-06 | 1998-11-26 | Henkel Kgaa | Detergensgemische und deren Verwendung |
| WO2000000490A2 (en) * | 1998-06-26 | 2000-01-06 | Eli Lilly And Company | 5-ht1f agonists |
| KR100537558B1 (ko) * | 1998-09-01 | 2005-12-19 | 가부시끼가이샤 하야시바라 세이부쓰 가가꾸 겐꾸조 | 인터류킨-18 결합 단백질 |
| EP1022027A1 (en) * | 1999-01-22 | 2000-07-26 | Applied Research Systems ARS Holding N.V. | Tumor necrosis factor antagonists and their use in endometriosis |
| AU3876600A (en) * | 1999-03-16 | 2000-10-04 | Cytovia, Inc. | Substituted 2-aminobenzamide caspase inhibitors and the use thereof |
| US6355618B1 (en) * | 1999-04-09 | 2002-03-12 | Cytovia, Inc. | Caspase inhibitors and the use thereof |
| AU6078500A (en) * | 1999-07-09 | 2001-01-30 | Amgen, Inc. | Combination therapy for conditions leading to bone loss |
| CA2399148A1 (en) * | 2000-02-10 | 2001-08-16 | Abbott Laboratories | Antibodies that bind human interleukin-18 and methods of making and using |
| CZ300792B6 (cs) * | 2000-05-05 | 2009-08-12 | Applied Research Systems Ars Holding N. V. | Farmaceutický prostredek |
| WO2002032374A2 (en) * | 2000-10-18 | 2002-04-25 | Immunex Corporation | Methods for treating il-18 mediated disorders |
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- 2002-01-28 HR HR20030609A patent/HRP20030609A2/xx not_active Application Discontinuation
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- 2002-01-28 AT AT02718052T patent/ATE380558T1/de active
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- 2002-01-28 KR KR1020037009941A patent/KR100857376B1/ko not_active Expired - Lifetime
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