MXPA03006776A - Uso de inhibidores de interleucina-18 para el tratamiento y/o prevencion de enfermedad cardiaca. - Google Patents

Uso de inhibidores de interleucina-18 para el tratamiento y/o prevencion de enfermedad cardiaca.

Info

Publication number
MXPA03006776A
MXPA03006776A MXPA03006776A MXPA03006776A MXPA03006776A MX PA03006776 A MXPA03006776 A MX PA03006776A MX PA03006776 A MXPA03006776 A MX PA03006776A MX PA03006776 A MXPA03006776 A MX PA03006776A MX PA03006776 A MXPA03006776 A MX PA03006776A
Authority
MX
Mexico
Prior art keywords
inhibitors
prevention
treatment
heart disease
heart
Prior art date
Application number
MXPA03006776A
Other languages
English (en)
Spanish (es)
Inventor
Charles Dinarello
Original Assignee
Applied Research Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems filed Critical Applied Research Systems
Publication of MXPA03006776A publication Critical patent/MXPA03006776A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/40Immunoglobulins specific features characterized by post-translational modification
    • C07K2317/41Glycosylation, sialylation, or fucosylation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cell Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
MXPA03006776A 2001-01-29 2002-01-28 Uso de inhibidores de interleucina-18 para el tratamiento y/o prevencion de enfermedad cardiaca. MXPA03006776A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01101959 2001-01-29
PCT/EP2002/000844 WO2002060479A1 (en) 2001-01-29 2002-01-28 Use of il-18 inhibitors for the treatment and/or prevention of heart disease

Publications (1)

Publication Number Publication Date
MXPA03006776A true MXPA03006776A (es) 2003-10-24

Family

ID=8176323

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA03006776A MXPA03006776A (es) 2001-01-29 2002-01-28 Uso de inhibidores de interleucina-18 para el tratamiento y/o prevencion de enfermedad cardiaca.

Country Status (31)

Country Link
US (1) US20040234523A1 (https=)
EP (1) EP1355668B1 (https=)
JP (2) JP4860897B2 (https=)
KR (1) KR100857376B1 (https=)
CN (1) CN1326562C (https=)
AR (1) AR032422A1 (https=)
AT (1) ATE380558T1 (https=)
BG (1) BG66483B1 (https=)
BR (1) BR0206819A (https=)
CA (1) CA2435466C (https=)
CY (1) CY1107203T1 (https=)
CZ (1) CZ305653B6 (https=)
DE (1) DE60224004T2 (https=)
DK (1) DK1355668T3 (https=)
EA (2) EA006767B1 (https=)
EE (1) EE05534B1 (https=)
ES (1) ES2295332T3 (https=)
HR (1) HRP20030609A2 (https=)
HU (1) HU229164B1 (https=)
IL (2) IL157024A0 (https=)
ME (1) ME00549B (https=)
MX (1) MXPA03006776A (https=)
NO (1) NO331083B1 (https=)
PL (1) PL213568B1 (https=)
PT (1) PT1355668E (https=)
RS (1) RS51125B (https=)
SI (1) SI1355668T1 (https=)
SK (1) SK287620B6 (https=)
UA (1) UA80676C2 (https=)
WO (1) WO2002060479A1 (https=)
ZA (1) ZA200305439B (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2399148A1 (en) 2000-02-10 2001-08-16 Abbott Laboratories Antibodies that bind human interleukin-18 and methods of making and using
JP2004528010A (ja) 2000-10-11 2004-09-16 バイロン・セラピューティックス・インコーポレーテッド 免疫モジュレーションのための核酸およびポリペプチド
US7718368B2 (en) 2000-12-04 2010-05-18 Viron Therapeutics Inc. Immunomodulatory protein and useful embodiments thereof
US20080076708A1 (en) 2003-05-13 2008-03-27 Valter Altarocca Active Variants of the Il-18 Binding Protein and Medical Uses Thereof
US7968684B2 (en) 2003-11-12 2011-06-28 Abbott Laboratories IL-18 binding proteins
JP4961559B2 (ja) * 2004-03-11 2012-06-27 友昭 星野 インターロイキン18阻害剤を有効成分とする疾患の予防又は治療剤
AU2006254103B2 (en) 2005-06-03 2012-09-06 Ares Trading S.A. Production of recombinant IL-18 binding protein
AU2006256763B2 (en) 2005-06-10 2012-08-02 Ares Trading S.A. Process for the purification of IL-18 binding protein
WO2009061832A1 (en) * 2007-11-05 2009-05-14 Kci Licensing Inc. Identification of tissue for debridement
US9376489B2 (en) 2012-09-07 2016-06-28 Novartis Ag IL-18 binding molecules
UA125204C2 (uk) * 2013-09-05 2022-02-02 Аб2 Біо Са Застосування il-18-зв'язувального білка (il-18bp) при запальних захворюваннях
US10882905B2 (en) 2015-03-05 2021-01-05 Ab2 Bio Sa IL-18 binding protein (IL-18BP) and antibodies in inflammatory diseases
WO2018013509A1 (en) * 2016-07-11 2018-01-18 Arizona Board Of Regents On Behalf Of The University Of Arizona Compositions and methods for diagnosing and treating arrhythmias

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6204261B1 (en) * 1995-12-20 2001-03-20 Vertex Pharmaceuticals Incorporated Inhibitors of interleukin-1β Converting enzyme inhibitors
US5605690A (en) * 1989-09-05 1997-02-25 Immunex Corporation Methods of lowering active TNF-α levels in mammals using tumor necrosis factor receptor
NZ322197A (en) * 1995-11-21 1999-02-25 Yamanouchi Pharma Co Ltd Pyrido[2,3-d] pyrimidine derivatives and pharmaceutical compositions thereof
AU738048B2 (en) * 1996-09-12 2001-09-06 Idun Pharmaceuticals, Inc. Inhibition of apoptosis using interleukin-1beta-converting enzyme (ICE)/CED-3 family inhibitors
ATE346085T1 (de) * 1996-12-06 2006-12-15 Vertex Pharma Inhibitoren des interleukin-1-beta konvertierenden enzyms
SK122199A3 (en) * 1997-03-18 2000-12-11 Basf Ag Methods and compositions for modulating responsiveness to corticosteroids
IL121860A0 (en) * 1997-08-14 1998-02-22 Yeda Res & Dev Interleukin-18 binding proteins their preparation and use
DE19743687C1 (de) * 1997-10-06 1998-11-26 Henkel Kgaa Detergensgemische und deren Verwendung
WO2000000490A2 (en) * 1998-06-26 2000-01-06 Eli Lilly And Company 5-ht1f agonists
KR100537558B1 (ko) * 1998-09-01 2005-12-19 가부시끼가이샤 하야시바라 세이부쓰 가가꾸 겐꾸조 인터류킨-18 결합 단백질
EP1022027A1 (en) * 1999-01-22 2000-07-26 Applied Research Systems ARS Holding N.V. Tumor necrosis factor antagonists and their use in endometriosis
AU3876600A (en) * 1999-03-16 2000-10-04 Cytovia, Inc. Substituted 2-aminobenzamide caspase inhibitors and the use thereof
US6355618B1 (en) * 1999-04-09 2002-03-12 Cytovia, Inc. Caspase inhibitors and the use thereof
AU6078500A (en) * 1999-07-09 2001-01-30 Amgen, Inc. Combination therapy for conditions leading to bone loss
CA2399148A1 (en) * 2000-02-10 2001-08-16 Abbott Laboratories Antibodies that bind human interleukin-18 and methods of making and using
CZ300792B6 (cs) * 2000-05-05 2009-08-12 Applied Research Systems Ars Holding N. V. Farmaceutický prostredek
WO2002032374A2 (en) * 2000-10-18 2002-04-25 Immunex Corporation Methods for treating il-18 mediated disorders

Also Published As

Publication number Publication date
CZ305653B6 (cs) 2016-01-27
DE60224004D1 (de) 2008-01-24
CA2435466C (en) 2012-04-03
WO2002060479A1 (en) 2002-08-08
CA2435466A1 (en) 2002-08-08
JP2009102354A (ja) 2009-05-14
ES2295332T3 (es) 2008-04-16
PL213568B1 (pl) 2013-03-29
JP4860897B2 (ja) 2012-01-25
EE200300328A (et) 2003-10-15
KR20030070143A (ko) 2003-08-27
SK287620B6 (sk) 2011-04-05
HK1062810A1 (en) 2004-11-26
HUP0303306A3 (en) 2005-12-28
AR032422A1 (es) 2003-11-05
ATE380558T1 (de) 2007-12-15
EA200300844A1 (ru) 2003-12-25
HUP0303306A2 (hu) 2004-01-28
ZA200305439B (en) 2004-07-15
PT1355668E (pt) 2008-01-04
EP1355668A1 (en) 2003-10-29
SI1355668T1 (sl) 2008-06-30
HRP20030609A2 (en) 2005-06-30
JP2004522748A (ja) 2004-07-29
KR100857376B1 (ko) 2008-09-05
CY1107203T1 (el) 2012-11-21
RS51125B (sr) 2010-10-31
US20040234523A1 (en) 2004-11-25
DE60224004T2 (de) 2009-07-23
CZ20032335A3 (en) 2004-07-14
CN1326562C (zh) 2007-07-18
YU57803A (sh) 2006-05-25
SK10892003A3 (sk) 2004-02-03
EA200501549A1 (ru) 2006-04-28
PL366802A1 (en) 2005-02-07
IL157024A0 (en) 2004-02-08
HU229164B1 (en) 2013-09-30
IL157024A (en) 2014-02-27
BG108128A (bg) 2004-11-30
ME00549B (me) 2011-10-10
EA010180B1 (ru) 2008-06-30
EA006767B1 (ru) 2006-04-28
EE05534B1 (et) 2012-04-16
UA80676C2 (en) 2007-10-25
NO331083B1 (no) 2011-10-03
EP1355668B1 (en) 2007-12-12
NO20033228L (no) 2003-09-26
BG66483B1 (bg) 2015-03-31
DK1355668T3 (da) 2008-05-05
NO20033228D0 (no) 2003-07-16
BR0206819A (pt) 2004-02-03
CN1499982A (zh) 2004-05-26

Similar Documents

Publication Publication Date Title
SI1487541T1 (sl) Uporaba inhibitorjev il-18 za zdravljenje in /alipreventivo bolezni perifernega oĺ˝ilja
AP2004003002A0 (en) azabicyclic-substituted fused-heteroaryl compoundsfor the treatment of disease.
IL159344A0 (en) Quinuclidines-substituted-multicyclic-heteroaryls for the treatment of disease
HUP0401127A3 (en) Treatment and diagnosis of macrophage disease
IL160389A0 (en) Use of flibanserin for the treatment of sexual disorders
AU2003290548A1 (en) Prevention and treatment of synucleinopathic disease
IL196301A0 (en) Medicament for the treatment of hapatitis c
ZA200409492B (en) Compositions and methods for the diagnosis and treatment of tumor.
AU2002367535A8 (en) Diagnosis and treatment of vascular disease
EP1392292A4 (en) PYRANOINDAZOLES AND THEIR USE IN GLAUCOMA TREATMENT
PL372928A1 (en) Use of osteoprotegerin for the treatment and/or prevention of fibrotic disease
ZA200208228B (en) Use of il-18 inhibitors for the treatment and/or prevention of athesclerosis
MXPA03006776A (es) Uso de inhibidores de interleucina-18 para el tratamiento y/o prevencion de enfermedad cardiaca.
AU2003291536A8 (en) Method for the diagnosis and treatment of vascular disease
ZA200307475B (en) Carbamate compounds for use in the treatment of pain.
GB0213869D0 (en) The treatment of pain
ZA200501288B (en) Substituted 5-chroman-5-yl-ethylamine compounds and their use for the treatment of glaucoma.
MXPA03003032A (es) Terapia de combinacion para el tratamiento de una enfermedad sensible a los estrogenos.
AU2002330724A1 (en) Diagnosis, prevention and treatment of cancer
AU2002366195A8 (en) Use of bisindolmaleimide and gemcitabine for the treatment of cancer
ZA200103250B (en) The treatment of immunomodulatory related and other diseases or conditions.
AU2002365654A8 (en) Treatment of diseases via the skin
AU2003287513A8 (en) Inhibitors of beta-secretase, and their use for the prevention or treatment of alzheimer's disease or mild cognitive impairment
ZA200308844B (en) Quinuclidines-substituted-multi-cyclic-heteroaryls for the treatment of disease.
GB0121046D0 (en) The diagnosis and treatment of airways disease

Legal Events

Date Code Title Description
GB Transfer or rights
FG Grant or registration