DOP2018000262A - Uso de indazoles sustituidos para el tratamiento y la prevención de enfermedades en animales - Google Patents

Uso de indazoles sustituidos para el tratamiento y la prevención de enfermedades en animales

Info

Publication number
DOP2018000262A
DOP2018000262A DO2018000262A DO2018000262A DOP2018000262A DO P2018000262 A DOP2018000262 A DO P2018000262A DO 2018000262 A DO2018000262 A DO 2018000262A DO 2018000262 A DO2018000262 A DO 2018000262A DO P2018000262 A DOP2018000262 A DO P2018000262A
Authority
DO
Dominican Republic
Prior art keywords
animals
treatment
diseases
indazols
prevention
Prior art date
Application number
DO2018000262A
Other languages
English (en)
Inventor
Bothe Ulrich
Bömer Ulf
Beddies Gerald
Foster Adrian
Schmidt Nicole
Nubbemeyer Reinhard
De Lourdes Mottier María
Original Assignee
Bayer Animal Health Gmbh
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Animal Health Gmbh, Bayer Pharma AG filed Critical Bayer Animal Health Gmbh
Publication of DOP2018000262A publication Critical patent/DOP2018000262A/es

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/04Drugs for disorders of the respiratory system for throat disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Otolaryngology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invención se refiere al uso de indazoles sustituidos en el tratamiento y/o profilaxis de enfermedades alérgicas y/o inflamatorias en animales, especialmente para el tratamiento y/o profilaxis de la dermatitis atópica, Dermatitis Alérgica por pulgas, enfermedad intestinal inflamatoria, osteoartritis y dolor inflamatorio, enfermedad de las vías respiratorias recurrente no infecciosa, hipersensibilidad a los insectos, asma, enfermedad respiratoria, mastitis y endometritis en animales.
DO2018000262A 2016-06-01 2018-11-30 Uso de indazoles sustituidos para el tratamiento y la prevención de enfermedades en animales DOP2018000262A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP16172544 2016-06-01

Publications (1)

Publication Number Publication Date
DOP2018000262A true DOP2018000262A (es) 2019-02-28

Family

ID=56097024

Family Applications (1)

Application Number Title Priority Date Filing Date
DO2018000262A DOP2018000262A (es) 2016-06-01 2018-11-30 Uso de indazoles sustituidos para el tratamiento y la prevención de enfermedades en animales

Country Status (25)

Country Link
US (2) US20200216413A1 (es)
EP (1) EP3464266B1 (es)
JP (1) JP7004677B2 (es)
KR (1) KR102547834B1 (es)
CN (1) CN109219603A (es)
AU (1) AU2017272505B9 (es)
BR (1) BR112018074927A2 (es)
CA (1) CA3025847A1 (es)
CL (1) CL2018003432A1 (es)
CO (1) CO2018013029A2 (es)
DK (1) DK3464266T3 (es)
DO (1) DOP2018000262A (es)
ES (1) ES2898771T3 (es)
IL (1) IL263132B (es)
MX (1) MX2018014899A (es)
MY (1) MY199070A (es)
PH (1) PH12018502530A1 (es)
PL (1) PL3464266T3 (es)
PT (1) PT3464266T (es)
RU (1) RU2743170C2 (es)
SG (1) SG11201809470RA (es)
SI (1) SI3464266T1 (es)
TW (1) TWI781935B (es)
UA (1) UA124237C2 (es)
WO (1) WO2017207481A1 (es)

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JO3705B1 (ar) 2014-11-26 2021-01-31 Bayer Pharma AG إندازولات مستبدلة جديدة، عمليات لتحضيرها، مستحضرات دوائية تحتوي عليها واستخدامها في إنتاج أدوية
CA3016364A1 (en) 2016-03-03 2017-09-08 Bayer Pharma Aktiengesellschaft New 2-substituted indazoles, methods for producing same, pharmaceutical preparations that contain same, and use of same to produce drugs
SI3448846T1 (sl) 2016-04-29 2021-09-30 Bayer Pharma Aktiengesellschaft Sinteza indazolov
CU24593B1 (es) 2016-04-29 2022-05-11 Bayer Pharma AG Formas cristalinas de n-[2-(3-hidroxi-3-metilbutil)-6-(2-hidroxipropan-2-il)-2h-indazol-5-il]-6-(trifluorometil)- piridin-2-carboxamida
SG11201810769QA (en) 2016-06-01 2018-12-28 Bayer Pharma AG Use of 2-substituted indazoles for the treatment and prophylaxis of autoimmune diseases
BR112020007679A2 (pt) 2017-10-19 2020-10-20 Bayer Animal Health Gmbh uso de pirrolidonas heteroaromáticas fundidas para tratamento e prevenção de doenças em animais.
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EP3800188A1 (en) 2019-10-02 2021-04-07 Bayer AG Substituted pyrazolopyrimidines as irak4 inhibitors
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CN113402499B (zh) 2021-06-21 2022-05-13 上海勋和医药科技有限公司 一种亚磺酰亚胺取代的吲唑类irak4激酶抑制剂、制备方法及用途

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SI3448846T1 (sl) * 2016-04-29 2021-09-30 Bayer Pharma Aktiengesellschaft Sinteza indazolov
CU24593B1 (es) * 2016-04-29 2022-05-11 Bayer Pharma AG Formas cristalinas de n-[2-(3-hidroxi-3-metilbutil)-6-(2-hidroxipropan-2-il)-2h-indazol-5-il]-6-(trifluorometil)- piridin-2-carboxamida
SG11201810769QA (en) * 2016-06-01 2018-12-28 Bayer Pharma AG Use of 2-substituted indazoles for the treatment and prophylaxis of autoimmune diseases

Also Published As

Publication number Publication date
PH12018502530A1 (en) 2019-10-21
MX2018014899A (es) 2019-04-24
WO2017207481A8 (en) 2018-11-22
US20220204474A1 (en) 2022-06-30
AU2017272505A8 (en) 2018-11-29
JP7004677B2 (ja) 2022-01-21
AU2017272505A1 (en) 2018-11-15
AU2017272505B2 (en) 2021-10-07
IL263132B (en) 2022-04-01
BR112018074927A2 (pt) 2019-03-12
TW201808933A (zh) 2018-03-16
RU2018145860A3 (es) 2020-07-09
CO2018013029A2 (es) 2018-12-28
CN109219603A (zh) 2019-01-15
UA124237C2 (uk) 2021-08-11
IL263132A (en) 2018-12-31
ES2898771T3 (es) 2022-03-08
CA3025847A1 (en) 2017-12-07
US20200216413A1 (en) 2020-07-09
SG11201809470RA (en) 2018-11-29
EP3464266A1 (en) 2019-04-10
JP2019520348A (ja) 2019-07-18
WO2017207481A1 (en) 2017-12-07
AU2017272505B9 (en) 2021-10-28
EP3464266B1 (en) 2021-10-20
SI3464266T1 (sl) 2021-12-31
RU2018145860A (ru) 2020-07-09
TWI781935B (zh) 2022-11-01
MY199070A (en) 2023-10-12
KR20190015252A (ko) 2019-02-13
RU2743170C2 (ru) 2021-02-15
PL3464266T3 (pl) 2022-01-24
PT3464266T (pt) 2021-11-23
CL2018003432A1 (es) 2019-03-22
DK3464266T3 (da) 2021-11-22
KR102547834B1 (ko) 2023-06-26

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