SG11201809470RA - Substituted indazoles useful for treatment and prevention of allergic and/or inflammatory diseases in animals - Google Patents
Substituted indazoles useful for treatment and prevention of allergic and/or inflammatory diseases in animalsInfo
- Publication number
- SG11201809470RA SG11201809470RA SG11201809470RA SG11201809470RA SG11201809470RA SG 11201809470R A SG11201809470R A SG 11201809470RA SG 11201809470R A SG11201809470R A SG 11201809470RA SG 11201809470R A SG11201809470R A SG 11201809470RA SG 11201809470R A SG11201809470R A SG 11201809470RA
- Authority
- SG
- Singapore
- Prior art keywords
- international
- animals
- treatment
- allergic
- berlin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Dermatology (AREA)
- Otolaryngology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16172544 | 2016-06-01 | ||
| PCT/EP2017/062876 WO2017207481A1 (en) | 2016-06-01 | 2017-05-29 | Substituted indazoles ueful for treatment and prevention of allergic and/or inflammatory diseases in animals |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201809470RA true SG11201809470RA (en) | 2018-11-29 |
Family
ID=56097024
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201809470RA SG11201809470RA (en) | 2016-06-01 | 2017-05-29 | Substituted indazoles useful for treatment and prevention of allergic and/or inflammatory diseases in animals |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US20200216413A1 (es) |
| EP (1) | EP3464266B1 (es) |
| JP (1) | JP7004677B2 (es) |
| KR (1) | KR102547834B1 (es) |
| CN (1) | CN109219603A (es) |
| AU (1) | AU2017272505B9 (es) |
| BR (1) | BR112018074927A2 (es) |
| CA (1) | CA3025847A1 (es) |
| CL (1) | CL2018003432A1 (es) |
| CO (1) | CO2018013029A2 (es) |
| DK (1) | DK3464266T3 (es) |
| DO (1) | DOP2018000262A (es) |
| ES (1) | ES2898771T3 (es) |
| IL (1) | IL263132B (es) |
| MX (1) | MX2018014899A (es) |
| MY (1) | MY199070A (es) |
| PH (1) | PH12018502530A1 (es) |
| PL (1) | PL3464266T3 (es) |
| PT (1) | PT3464266T (es) |
| RU (1) | RU2743170C2 (es) |
| SG (1) | SG11201809470RA (es) |
| SI (1) | SI3464266T1 (es) |
| TW (1) | TWI781935B (es) |
| UA (1) | UA124237C2 (es) |
| WO (1) | WO2017207481A1 (es) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JO3705B1 (ar) | 2014-11-26 | 2021-01-31 | Bayer Pharma AG | إندازولات مستبدلة جديدة، عمليات لتحضيرها، مستحضرات دوائية تحتوي عليها واستخدامها في إنتاج أدوية |
| US10435396B2 (en) | 2016-03-03 | 2019-10-08 | Bayer Pharma Aktiegesellschaft | 2-substituted indazoles, methods for producing same, pharmaceutical preparations that contain same, and use of same to produce drugs |
| WO2017186689A1 (en) | 2016-04-29 | 2017-11-02 | Bayer Pharma Aktiengesellschaft | Synthesis of indazoles |
| AU2017256659B2 (en) | 2016-04-29 | 2021-05-27 | Bayer Pharma Aktiengesellschaft | Synthesis of indazoles |
| SG11201810769QA (en) * | 2016-06-01 | 2018-12-28 | Bayer Pharma AG | Use of 2-substituted indazoles for the treatment and prophylaxis of autoimmune diseases |
| MX2020004155A (es) | 2017-10-19 | 2020-08-03 | Bayer Animal Health Gmbh | Uso de pirrolidonas heteroaromaticas fusionadas para el tratamiento y prevencion de enfermedades en animales. |
| CN110835338A (zh) * | 2018-08-17 | 2020-02-25 | 浙江海正药业股份有限公司 | 咪唑并吡啶类衍生物及其制备方法和其在医药上的用途 |
| US20220241410A1 (en) | 2019-05-23 | 2022-08-04 | The University Of Montana | Vaccine adjuvants based on tlr receptor ligands |
| WO2021057785A1 (zh) * | 2019-09-24 | 2021-04-01 | 上海美悦生物科技发展有限公司 | 一种irak抑制剂及其制备方法和用途 |
| EP3800188A1 (en) | 2019-10-02 | 2021-04-07 | Bayer AG | Substituted pyrazolopyrimidines as irak4 inhibitors |
| JP7429032B2 (ja) * | 2019-12-24 | 2024-02-07 | 学校法人順天堂 | 間質性肺炎モデル非ヒト動物の作製方法 |
| CN113521079A (zh) * | 2020-04-20 | 2021-10-22 | 上海领泰生物医药科技有限公司 | Irak4抑制剂在治疗ali/ards中的应用 |
| CN115300627B (zh) * | 2021-05-08 | 2024-01-26 | 中南大学湘雅医院 | 钠-葡萄糖共转运蛋白2抑制剂的应用、一种药物组合物及其应用 |
| CN113402499B (zh) | 2021-06-21 | 2022-05-13 | 上海勋和医药科技有限公司 | 一种亚磺酰亚胺取代的吲唑类irak4激酶抑制剂、制备方法及用途 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0313122A (pt) * | 2002-07-31 | 2005-07-05 | Schering Ag | Antranilamidopiridinas inibidoras de vegfr-2 e vegfr-3 |
| EP1646608B1 (en) | 2003-06-25 | 2011-03-02 | JE IL Pharmaceutical Co., Ltd. | Tricyclic derivatives or pharmaceutically acceptable salts thereof, their preparations and pharmaceutical compositions containing them |
| WO2005082866A2 (en) | 2004-02-20 | 2005-09-09 | Pfizer Limited | Substituted 1, 2, 4- triazole derivatives as oxytocin antagonists |
| JP2008523046A (ja) | 2004-12-08 | 2008-07-03 | ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー | メチレン誘導体 |
| TWI370820B (en) | 2005-04-27 | 2012-08-21 | Takeda Pharmaceutical | Fused heterocyclic compounds |
| US7745477B2 (en) | 2006-02-07 | 2010-06-29 | Hoffman-La Roche Inc. | Heteroaryl and benzyl amide compounds |
| MX2008010193A (es) | 2006-02-10 | 2008-11-27 | Summit Corp Plc | Tratamiento de distrofia muscular de duchenne. |
| EP2045253A4 (en) | 2006-06-29 | 2013-01-23 | Nissan Chemical Ind Ltd | alpha-amino acid derivative and pharmaceutical agent containing it as an active ingredient |
| WO2008030584A2 (en) | 2006-09-07 | 2008-03-13 | Biogen Idec Ma Inc. | Indazole derivatives as modulators of interleukin- 1 receptor-associated kinase |
| WO2009117421A2 (en) | 2008-03-17 | 2009-09-24 | Kalypsys, Inc. | Heterocyclic modulators of gpr119 for treatment of disease |
| US20100094000A1 (en) | 2008-09-03 | 2010-04-15 | Takeda Pharmaceutical Company Limited | Pyrazole compounds |
| WO2011153588A1 (en) | 2010-06-10 | 2011-12-15 | Biota Scientific Management Pty Ltd | Viral polymerase inhibitors |
| US20140113898A1 (en) | 2010-11-08 | 2014-04-24 | Zalicus Pharmaceuticals Ltd. | Bisarylsulfone and dialkylarylsulfone compounds as calcium channel blockers |
| HUE029617T2 (en) | 2010-12-20 | 2017-03-28 | Merck Serono Sa | Indazolyl triazole derivatives as IRAK inhibitors |
| US8748432B2 (en) | 2011-02-10 | 2014-06-10 | Syngenta Participations Ag | Microbiocidal pyrazole derivatives |
| EP2489663A1 (en) | 2011-02-16 | 2012-08-22 | Almirall, S.A. | Compounds as syk kinase inhibitors |
| US10385070B2 (en) | 2011-02-18 | 2019-08-20 | Vertex Pharmaceuticals Incorporated | Chroman-spirocyclic piperidine amides as modulators of ion channels |
| US8575336B2 (en) * | 2011-07-27 | 2013-11-05 | Pfizer Limited | Indazoles |
| WO2013042137A1 (en) * | 2011-09-19 | 2013-03-28 | Aurigene Discovery Technologies Limited | Bicyclic heterocycles as irak4 inhibitors |
| WO2013106254A1 (en) | 2012-01-11 | 2013-07-18 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
| JP6234444B2 (ja) | 2012-05-21 | 2017-11-22 | バイエル ファーマ アクチエンゲゼルシャフト | チエノピリミジン類 |
| WO2015017336A1 (en) * | 2013-07-29 | 2015-02-05 | OmniGen Research, L.L.C. | Combination and method for administration to an animal |
| TWI667233B (zh) | 2013-12-19 | 2019-08-01 | 德商拜耳製藥公司 | 新穎吲唑羧醯胺，其製備方法、含彼等之醫藥製劑及其製造醫藥之用途 |
| AU2015205348A1 (en) | 2014-01-10 | 2016-07-28 | Aurigene Discovery Technologies Limited | Indazole compounds as IRAK4 inhibitors |
| CN104093061B (zh) * | 2014-07-18 | 2020-06-02 | 北京智谷睿拓技术服务有限公司 | 内容分享方法和装置 |
| JO3705B1 (ar) * | 2014-11-26 | 2021-01-31 | Bayer Pharma AG | إندازولات مستبدلة جديدة، عمليات لتحضيرها، مستحضرات دوائية تحتوي عليها واستخدامها في إنتاج أدوية |
| UY36660A (es) * | 2015-04-30 | 2016-11-30 | Bayer Pharma AG | Combinaciones de inhibidores de irak4 |
| AU2017256659B2 (en) * | 2016-04-29 | 2021-05-27 | Bayer Pharma Aktiengesellschaft | Synthesis of indazoles |
| WO2017186689A1 (en) * | 2016-04-29 | 2017-11-02 | Bayer Pharma Aktiengesellschaft | Synthesis of indazoles |
| SG11201810769QA (en) * | 2016-06-01 | 2018-12-28 | Bayer Pharma AG | Use of 2-substituted indazoles for the treatment and prophylaxis of autoimmune diseases |
-
2017
- 2017-05-29 JP JP2018563160A patent/JP7004677B2/ja active Active
- 2017-05-29 MY MYPI2018002212A patent/MY199070A/en unknown
- 2017-05-29 BR BR112018074927-3A patent/BR112018074927A2/pt not_active Application Discontinuation
- 2017-05-29 CA CA3025847A patent/CA3025847A1/en active Pending
- 2017-05-29 SG SG11201809470RA patent/SG11201809470RA/en unknown
- 2017-05-29 AU AU2017272505A patent/AU2017272505B9/en active Active
- 2017-05-29 WO PCT/EP2017/062876 patent/WO2017207481A1/en unknown
- 2017-05-29 UA UAA201812729A patent/UA124237C2/uk unknown
- 2017-05-29 RU RU2018145860A patent/RU2743170C2/ru active
- 2017-05-29 EP EP17725976.9A patent/EP3464266B1/en active Active
- 2017-05-29 MX MX2018014899A patent/MX2018014899A/es unknown
- 2017-05-29 KR KR1020187034447A patent/KR102547834B1/ko active IP Right Grant
- 2017-05-29 DK DK17725976.9T patent/DK3464266T3/da active
- 2017-05-29 PT PT177259769T patent/PT3464266T/pt unknown
- 2017-05-29 ES ES17725976T patent/ES2898771T3/es active Active
- 2017-05-29 SI SI201730981T patent/SI3464266T1/sl unknown
- 2017-05-29 CN CN201780034405.9A patent/CN109219603A/zh active Pending
- 2017-05-29 PL PL17725976T patent/PL3464266T3/pl unknown
- 2017-05-29 US US16/306,235 patent/US20200216413A1/en not_active Abandoned
- 2017-06-01 TW TW106118035A patent/TWI781935B/zh active
-
2018
- 2018-11-19 IL IL263132A patent/IL263132B/en unknown
- 2018-11-29 PH PH12018502530A patent/PH12018502530A1/en unknown
- 2018-11-30 DO DO2018000262A patent/DOP2018000262A/es unknown
- 2018-11-30 CL CL2018003432A patent/CL2018003432A1/es unknown
- 2018-11-30 CO CONC2018/0013029A patent/CO2018013029A2/es unknown
-
2022
- 2022-01-07 US US17/570,550 patent/US20220204474A1/en active Pending
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