DOP2012000089A - Anticuerpos monoclonales - Google Patents

Anticuerpos monoclonales

Info

Publication number
DOP2012000089A
DOP2012000089A DO2012000089A DO2012000089A DOP2012000089A DO P2012000089 A DOP2012000089 A DO P2012000089A DO 2012000089 A DO2012000089 A DO 2012000089A DO 2012000089 A DO2012000089 A DO 2012000089A DO P2012000089 A DOP2012000089 A DO P2012000089A
Authority
DO
Dominican Republic
Prior art keywords
fibrinogen
fibrin
domain
vectors
monoclonal antibodies
Prior art date
Application number
DO2012000089A
Other languages
English (en)
Spanish (es)
Inventor
Katerina Akassoglou
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Publication of DOP2012000089A publication Critical patent/DOP2012000089A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Transplantation (AREA)
  • Psychiatry (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DO2012000089A 2009-10-02 2012-03-29 Anticuerpos monoclonales DOP2012000089A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24801409P 2009-10-02 2009-10-02

Publications (1)

Publication Number Publication Date
DOP2012000089A true DOP2012000089A (es) 2012-06-30

Family

ID=43826649

Family Applications (1)

Application Number Title Priority Date Filing Date
DO2012000089A DOP2012000089A (es) 2009-10-02 2012-03-29 Anticuerpos monoclonales

Country Status (38)

Country Link
US (1) US8877195B2 (https=)
EP (1) EP2483416B1 (https=)
JP (1) JP5883389B2 (https=)
KR (1) KR101793221B1 (https=)
CN (1) CN102575277B (https=)
AR (1) AR078490A1 (https=)
AU (1) AU2010300559B2 (https=)
BR (1) BR112012008370B8 (https=)
CA (1) CA2774256C (https=)
CL (1) CL2012000788A1 (https=)
CO (1) CO6440561A2 (https=)
CR (1) CR20120127A (https=)
CY (1) CY1118540T1 (https=)
DK (1) DK2483416T3 (https=)
DO (1) DOP2012000089A (https=)
EA (1) EA023477B1 (https=)
ES (1) ES2614939T3 (https=)
GE (2) GEP20156214B (https=)
GT (1) GT201200096A (https=)
HR (1) HRP20170110T1 (https=)
HU (1) HUE031571T2 (https=)
IL (1) IL218621B (https=)
IN (1) IN2012DN03154A (https=)
LT (1) LT2483416T (https=)
MA (1) MA33704B1 (https=)
MX (1) MX2012003811A (https=)
MY (1) MY159359A (https=)
NZ (1) NZ598770A (https=)
PH (1) PH12012500551A1 (https=)
PL (1) PL2483416T3 (https=)
PT (1) PT2483416T (https=)
SI (1) SI2483416T1 (https=)
SM (2) SMT201700083T1 (https=)
TN (1) TN2012000149A1 (https=)
TW (1) TWI511741B (https=)
UA (1) UA108860C2 (https=)
WO (1) WO2011041518A1 (https=)
ZA (1) ZA201202227B (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011056561A1 (en) 2009-10-27 2011-05-12 Beth Israel Deaconess Medical Center Methods and compositions for the generation and use of conformation-specific antibodies
WO2012125724A1 (en) 2011-03-14 2012-09-20 Beth Israel Deaconess Medical Center Methods and compositions for the treatment of proliferative disorders
US10487114B2 (en) 2011-04-27 2019-11-26 Beth Israel Deaconess Medical Center, Inc. Methods for administering peptides for the generation of effective c/s conformation-specific antibodies to a human subject in need thereof
WO2012162698A1 (en) 2011-05-26 2012-11-29 Beth Israel Deaconess Medical Center, Inc. Methods and compositions for the treatment of immune disorders
WO2013185055A1 (en) 2012-06-07 2013-12-12 Beth Israel Deaconess Medical Center, Inc. Methods and compositions for the inhibition of pin1
EP2968548B1 (en) * 2013-03-15 2020-09-09 Beth Israel Deaconess Medical Center, Inc. Methods and compositions for the generation and use of conformation-specific antibodies
EP3091996B1 (en) * 2014-01-11 2024-04-10 The J. David Gladstone Institutes, A Testamentary Trust Established under The Will of J. David Gladstone Compositions and methods for in vitro assays of fibrin activity
WO2016011268A1 (en) 2014-07-17 2016-01-21 Beth Israel Deaconess Medical Center, Inc. Atra for modulating pin1 activity and stability
WO2016011265A2 (en) 2014-07-17 2016-01-21 Beth Israel Deaconess Medical Center, Inc. Biomarkers for pin1-associated disorders
US10548864B2 (en) 2015-03-12 2020-02-04 Beth Israel Deaconess Medical Center, Inc. Enhanced ATRA-related compounds for the treatment of proliferative diseases, autoimmune diseases, and addiction conditions
SG11201910113PA (en) * 2017-05-02 2019-11-28 Nat Cancer Center Japan Plasmin-cleavable anti-insoluble fibrin antibody-drug conjugate
CA3178880A1 (en) 2020-03-31 2021-10-07 National Cancer Center Fibrin-binding antibody and pharmaceutical composition containing antibody
WO2022133028A1 (en) * 2020-12-16 2022-06-23 The J. David Gladstone Institutes, A Testamentary Trust Established Under The Will Of J. David Gladstone Use of fibrin-targeting immunotherapy to reduce coronavirus pathogenesis
WO2022159776A1 (en) * 2021-01-21 2022-07-28 Therini Bio, Inc. Antibodies which bind human fibrin and methods of use
US20240279321A1 (en) * 2021-06-18 2024-08-22 Therini Bio, Inc. ANTIBODIES WHICH BIND HUMAN FIBRIN OR FIBRINOGEN yC DOMAIN AND METHODS OF USE
WO2022266539A2 (en) * 2021-06-18 2022-12-22 Therini Bio, Inc. ANTIBODIES WHICH BIND HUMAN FIBRIN OR FIBRINOGEN γC DOMAIN AND METHODS OF USE
WO2024044583A1 (en) * 2022-08-22 2024-02-29 The J. David Gladstone Institutes, A Testamentary Trust Established Under The Will Of J. David Gladstone Human anti-fibrin antibodies and uses thereof
EP4676499A2 (en) * 2023-03-10 2026-01-14 The J. David Gladstone Institutes, A Testamentary Trust Established under The Will of J. David Gladstone Methods and compositions for cellular immunotherapy- fib4

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030031675A1 (en) * 2000-06-06 2003-02-13 Mikesell Glen E. B7-related nucleic acids and polypeptides useful for immunomodulation
EP2314620B1 (en) * 2004-05-27 2013-06-05 Crucell Holland B.V. Method of identifying binding molecules capable of neutralizing rabies virus
WO2007038407A2 (en) * 2005-09-23 2007-04-05 The Regents Of The University Of California Compositions and methods for treating nervous system disorders

Also Published As

Publication number Publication date
HK1168871A1 (zh) 2013-01-11
EP2483416B1 (en) 2016-11-23
MY159359A (en) 2016-12-30
ZA201202227B (en) 2014-11-26
JP5883389B2 (ja) 2016-03-15
AR078490A1 (es) 2011-11-09
CL2012000788A1 (es) 2012-09-14
TN2012000149A1 (en) 2013-09-19
JP2013506425A (ja) 2013-02-28
IL218621B (en) 2018-07-31
BR112012008370A2 (pt) 2016-11-29
MX2012003811A (es) 2012-05-08
SI2483416T1 (sl) 2017-06-30
BR112012008370B8 (pt) 2021-05-25
NZ598770A (en) 2014-01-31
CY1118540T1 (el) 2017-07-12
GT201200096A (es) 2014-12-23
CO6440561A2 (es) 2012-05-15
SMT201700083B (it) 2017-03-08
UA108860C2 (xx) 2015-06-25
HUE031571T2 (en) 2017-07-28
PH12012500551A1 (en) 2016-03-11
ES2614939T3 (es) 2017-06-02
LT2483416T (lt) 2017-04-25
HRP20170110T1 (hr) 2017-03-24
CR20120127A (es) 2012-05-28
IN2012DN03154A (https=) 2015-09-18
EP2483416A1 (en) 2012-08-08
AU2010300559A1 (en) 2012-04-05
MA33704B1 (fr) 2012-10-01
CN102575277B (zh) 2015-07-29
US8877195B2 (en) 2014-11-04
BR112012008370B1 (pt) 2020-12-22
GEP20166458B (en) 2016-04-11
CN102575277A (zh) 2012-07-11
GEP20156214B (en) 2015-01-12
TWI511741B (zh) 2015-12-11
PL2483416T3 (pl) 2017-05-31
EP2483416A4 (en) 2013-06-26
DK2483416T3 (en) 2017-02-20
SMT201700083T1 (it) 2017-03-08
PT2483416T (pt) 2017-02-14
WO2011041518A1 (en) 2011-04-07
AU2010300559B2 (en) 2014-11-27
KR20120094924A (ko) 2012-08-27
CA2774256C (en) 2019-02-19
EA023477B1 (ru) 2016-06-30
IL218621A0 (en) 2012-05-31
CA2774256A1 (en) 2011-04-07
TW201116298A (en) 2011-05-16
US20120183560A1 (en) 2012-07-19
EA201270416A1 (ru) 2012-08-30
KR101793221B1 (ko) 2017-11-02

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