LT2483416T - Monokloniniai antikūnai - Google Patents

Monokloniniai antikūnai

Info

Publication number
LT2483416T
LT2483416T LTEP10821238.2T LT10821238T LT2483416T LT 2483416 T LT2483416 T LT 2483416T LT 10821238 T LT10821238 T LT 10821238T LT 2483416 T LT2483416 T LT 2483416T
Authority
LT
Lithuania
Prior art keywords
monoclonal antibodies
monoclonal
antibodies
Prior art date
Application number
LTEP10821238.2T
Other languages
English (en)
Inventor
Katerina Akassoglou
Original Assignee
The Regents Of The University Of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Regents Of The University Of California filed Critical The Regents Of The University Of California
Publication of LT2483416T publication Critical patent/LT2483416T/lt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rheumatology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Transplantation (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Vascular Medicine (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
LTEP10821238.2T 2009-10-02 2010-09-30 Monokloniniai antikūnai LT2483416T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24801409P 2009-10-02 2009-10-02
PCT/US2010/050873 WO2011041518A1 (en) 2009-10-02 2010-09-30 Monoclonal antibodies

Publications (1)

Publication Number Publication Date
LT2483416T true LT2483416T (lt) 2017-04-25

Family

ID=43826649

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP10821238.2T LT2483416T (lt) 2009-10-02 2010-09-30 Monokloniniai antikūnai

Country Status (38)

Country Link
US (1) US8877195B2 (lt)
EP (1) EP2483416B1 (lt)
JP (1) JP5883389B2 (lt)
KR (1) KR101793221B1 (lt)
CN (1) CN102575277B (lt)
AR (1) AR078490A1 (lt)
AU (1) AU2010300559B2 (lt)
BR (1) BR112012008370B8 (lt)
CA (1) CA2774256C (lt)
CL (1) CL2012000788A1 (lt)
CO (1) CO6440561A2 (lt)
CR (1) CR20120127A (lt)
CY (1) CY1118540T1 (lt)
DK (1) DK2483416T3 (lt)
DO (1) DOP2012000089A (lt)
EA (1) EA023477B1 (lt)
ES (1) ES2614939T3 (lt)
GE (2) GEP20156214B (lt)
GT (1) GT201200096A (lt)
HK (1) HK1168871A1 (lt)
HR (1) HRP20170110T1 (lt)
HU (1) HUE031571T2 (lt)
IL (1) IL218621B (lt)
IN (1) IN2012DN03154A (lt)
LT (1) LT2483416T (lt)
MA (1) MA33704B1 (lt)
MX (1) MX2012003811A (lt)
MY (1) MY159359A (lt)
NZ (1) NZ598770A (lt)
PL (1) PL2483416T3 (lt)
PT (1) PT2483416T (lt)
SI (1) SI2483416T1 (lt)
SM (1) SMT201700083B (lt)
TN (1) TN2012000149A1 (lt)
TW (1) TWI511741B (lt)
UA (1) UA108860C2 (lt)
WO (1) WO2011041518A1 (lt)
ZA (1) ZA201202227B (lt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8771693B2 (en) 2009-10-27 2014-07-08 Beth Israel Deaconess Medical Center, Inc. Methods and compositions for the generation and use of conformation-specific antibodies
US10485780B2 (en) 2011-03-14 2019-11-26 Beth Israel Deaconess Medical Center, Inc. Methods and compositions for the treatment of proliferative disorders
US10487114B2 (en) 2011-04-27 2019-11-26 Beth Israel Deaconess Medical Center, Inc. Methods for administering peptides for the generation of effective c/s conformation-specific antibodies to a human subject in need thereof
US9439884B2 (en) 2011-05-26 2016-09-13 Beth Israel Deaconess Medical Center, Inc. Methods for the treatment of immune disorders
EP2858648B1 (en) 2012-06-07 2018-08-22 Beth Israel Deaconess Medical Center, Inc. Methods and compositions for the inhibition of pin1
EP2968548B1 (en) * 2013-03-15 2020-09-09 Beth Israel Deaconess Medical Center, Inc. Methods and compositions for the generation and use of conformation-specific antibodies
WO2015106072A1 (en) 2014-01-11 2015-07-16 The J. David Gladstone Institutes Compositions and methods for in vitro assays of fibrin activity
WO2016011268A1 (en) 2014-07-17 2016-01-21 Beth Israel Deaconess Medical Center, Inc. Atra for modulating pin1 activity and stability
WO2016011265A2 (en) 2014-07-17 2016-01-21 Beth Israel Deaconess Medical Center, Inc. Biomarkers for pin1-associated disorders
WO2016145186A1 (en) 2015-03-12 2016-09-15 Beth Israel Deaconess Medical Center, Inc. Enhanced atra-related compounds for the treatment of proliferative diseases, autoimmune diseases, and addiction conditions
SG11201910113PA (en) * 2017-05-02 2019-11-28 Nat Cancer Center Japan Plasmin-cleavable anti-insoluble fibrin antibody-drug conjugate
WO2021200932A1 (ja) * 2020-03-31 2021-10-07 国立研究開発法人国立がん研究センター フィブリンに結合する抗体および当該抗体を含む医薬組成物
EP4262870A1 (en) * 2020-12-16 2023-10-25 The J. David Gladstone Institutes, A Testamentary Trust Established under The Will of J. David Gladstone Use of fibrin-targeting immunotherapy to reduce coronavirus pathogenesis
WO2022159776A1 (en) * 2021-01-21 2022-07-28 Therini Bio, Inc. Antibodies which bind human fibrin and methods of use
EP4355772A2 (en) * 2021-06-18 2024-04-24 Therini Bio, Inc. Antibodies which bind human fibrin or fibrinogen ?c domain and methods of use
KR20240049265A (ko) * 2021-06-18 2024-04-16 테리니 바이오, 인코포레이티드 인간 피브린 또는 피브리노겐 γC 도메인에 결합하는 항체 및 사용 방법
WO2024044583A1 (en) * 2022-08-22 2024-02-29 The J. David Gladstone Institutes, A Testamentary Trust Established Under The Will Of J. David Gladstone Human anti-fibrin antibodies and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030031675A1 (en) * 2000-06-06 2003-02-13 Mikesell Glen E. B7-related nucleic acids and polypeptides useful for immunomodulation
ES2468021T3 (es) * 2004-05-27 2014-06-13 Crucell Holland B.V. Moléculas de unión que pueden neutralizar el virus de la rabia y usos de las mismas
US7807645B2 (en) * 2005-09-23 2010-10-05 The Regents Of The University Of California Method of treating degenerative disorders of the nervous system by administration of fibrinogen fragment

Also Published As

Publication number Publication date
MX2012003811A (es) 2012-05-08
EA201270416A1 (ru) 2012-08-30
CR20120127A (es) 2012-05-28
DOP2012000089A (es) 2012-06-30
CY1118540T1 (el) 2017-07-12
BR112012008370A2 (pt) 2016-11-29
KR101793221B1 (ko) 2017-11-02
GT201200096A (es) 2014-12-23
IL218621B (en) 2018-07-31
US20120183560A1 (en) 2012-07-19
UA108860C2 (xx) 2015-06-25
NZ598770A (en) 2014-01-31
JP2013506425A (ja) 2013-02-28
PT2483416T (pt) 2017-02-14
HUE031571T2 (en) 2017-07-28
TW201116298A (en) 2011-05-16
EP2483416A1 (en) 2012-08-08
CL2012000788A1 (es) 2012-09-14
IN2012DN03154A (lt) 2015-09-18
SMT201700083B (it) 2017-03-08
CA2774256C (en) 2019-02-19
MY159359A (en) 2016-12-30
BR112012008370B8 (pt) 2021-05-25
TN2012000149A1 (en) 2013-09-19
ZA201202227B (en) 2014-11-26
BR112012008370B1 (pt) 2020-12-22
CA2774256A1 (en) 2011-04-07
EP2483416B1 (en) 2016-11-23
HRP20170110T1 (hr) 2017-03-24
HK1168871A1 (zh) 2013-01-11
EA023477B1 (ru) 2016-06-30
TWI511741B (zh) 2015-12-11
PL2483416T3 (pl) 2017-05-31
SI2483416T1 (sl) 2017-06-30
US8877195B2 (en) 2014-11-04
JP5883389B2 (ja) 2016-03-15
CN102575277B (zh) 2015-07-29
GEP20156214B (en) 2015-01-12
AR078490A1 (es) 2011-11-09
EP2483416A4 (en) 2013-06-26
ES2614939T3 (es) 2017-06-02
CN102575277A (zh) 2012-07-11
MA33704B1 (fr) 2012-10-01
AU2010300559A1 (en) 2012-04-05
CO6440561A2 (es) 2012-05-15
IL218621A0 (en) 2012-05-31
WO2011041518A1 (en) 2011-04-07
KR20120094924A (ko) 2012-08-27
GEP20166458B (en) 2016-04-11
AU2010300559B2 (en) 2014-11-27
DK2483416T3 (en) 2017-02-20

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