DK456389A - Broforbundne bicycliske imider med en 4-oe4-(3-benzisothiazolyl)-1-piperazinylaabutylgruppe knyttet til imidnitrogenatomer og antipsykotisk farmaceutiske praeparater indeholdende disse - Google Patents

Broforbundne bicycliske imider med en 4-oe4-(3-benzisothiazolyl)-1-piperazinylaabutylgruppe knyttet til imidnitrogenatomer og antipsykotisk farmaceutiske praeparater indeholdende disse Download PDF

Info

Publication number
DK456389A
DK456389A DK456389A DK456389A DK456389A DK 456389 A DK456389 A DK 456389A DK 456389 A DK456389 A DK 456389A DK 456389 A DK456389 A DK 456389A DK 456389 A DK456389 A DK 456389A
Authority
DK
Denmark
Prior art keywords
benzisothiazolyl
piperazinylaabutyl
imidnitrogen
antipsycotic
atoms
Prior art date
Application number
DK456389A
Other languages
English (en)
Other versions
DK456389D0 (da
DK175200B1 (da
Inventor
Gene Michael Bright
Iii John Adams Lowe
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of DK456389D0 publication Critical patent/DK456389D0/da
Publication of DK456389A publication Critical patent/DK456389A/da
Application granted granted Critical
Publication of DK175200B1 publication Critical patent/DK175200B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK198904563A 1988-09-16 1989-09-15 Broforbundne bicycliske imider med en 4-[4-(3-benzisothiazolyl)-1-piperazinyl]butylgruppe knyttet til imidnitrogenatomer og antipsykotisk farmaceutiske præparater indeholdende disse DK175200B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/US1988/003230 WO1990002552A1 (en) 1988-09-16 1988-09-16 Antipsychotic 4-[4-(3-benzisothiazolyl)-1-piperazinyl]butyl bridged bicyclic imides
US8803230 1988-09-16

Publications (3)

Publication Number Publication Date
DK456389D0 DK456389D0 (da) 1989-09-15
DK456389A true DK456389A (da) 1990-03-17
DK175200B1 DK175200B1 (da) 2004-07-05

Family

ID=22208913

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198904563A DK175200B1 (da) 1988-09-16 1989-09-15 Broforbundne bicycliske imider med en 4-[4-(3-benzisothiazolyl)-1-piperazinyl]butylgruppe knyttet til imidnitrogenatomer og antipsykotisk farmaceutiske præparater indeholdende disse

Country Status (20)

Country Link
US (1) US5077295A (da)
EP (1) EP0364091B1 (da)
JP (1) JPH0631231B2 (da)
KR (1) KR930002568B1 (da)
AT (1) ATE92063T1 (da)
AU (1) AU607354B2 (da)
CA (1) CA1339314C (da)
DE (1) DE68907845T2 (da)
DK (1) DK175200B1 (da)
ES (1) ES2058542T3 (da)
FI (1) FI911285A0 (da)
HU (1) HUT61760A (da)
IE (1) IE61413B1 (da)
IL (1) IL91552A (da)
MY (1) MY104207A (da)
NO (1) NO911042L (da)
NZ (1) NZ230672A (da)
PT (1) PT91703B (da)
WO (1) WO1990002552A1 (da)
ZA (1) ZA897049B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5235283A (en) * 1991-02-07 1993-08-10 Siemens Aktiengesellschaft Gradient coil system for a nuclear magnetic resonance tomography apparatus which reduces acoustic noise
PT790236E (pt) * 1996-02-13 2004-04-30 Pfizer Pro-farmacos de 5-(2-(4-(1,2-benzisotiazol-3-il)-1-piperazinil)-etil-6-cloro-1,3-di-hidro-2h-indol-2-ona
US6084097A (en) * 1997-10-20 2000-07-04 Council Of Scientific & Industrial Research Methods for preparing 1-[4-arylpiperazin-1-yl]-3-[2-oxopyrrolidin/piperidin-1-yl] propanes
JP6440625B2 (ja) 2012-11-14 2018-12-19 ザ・ジョンズ・ホプキンス・ユニバーシティー 精神分裂病を処置するための方法および組成物

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE759371A (fr) * 1969-11-24 1971-05-24 Bristol Myers Co Azaspirodecanediones heterocycliques et procedes pour leur preparation
US4411901A (en) * 1981-12-23 1983-10-25 Mead Johnson & Company Benzisothiazole and benzisoxazole piperazine derivatives
US4507303A (en) * 1981-12-22 1985-03-26 Sumitomo Chemical Company, Limited Succinimide derivatives, compositions and method of use
US4452799A (en) * 1981-12-23 1984-06-05 Mead Johnson & Company Benzisothiazole and benzisoxazole piperazine derivatives
US4423049A (en) * 1981-12-28 1983-12-27 Mead Johnson & Company 2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyrimidines
JPS5995267A (ja) * 1982-11-25 1984-06-01 Eisai Co Ltd カルボン酸イミド誘導体およびその製造方法
US4524206A (en) * 1983-09-12 1985-06-18 Mead Johnson & Company 1-Heteroaryl-4-(2,5-pyrrolidinedion-1-yl)alkyl)piperazine derivatives
US4562255A (en) * 1984-03-30 1985-12-31 American Home Products Corporation Substituted bi-alicyclic imides
US4585773A (en) * 1984-07-11 1986-04-29 Bristol-Myers Company Isoindolinyl-alkyl-piperazines
US4590196A (en) * 1984-08-23 1986-05-20 Bristol-Myers Company Analgesic 1,2-benzisothiazol-3-ylpiperazine derivatives
JPH0625181B2 (ja) * 1985-03-27 1994-04-06 住友製薬株式会社 新規なイミド誘導体
US4656173A (en) * 1985-04-24 1987-04-07 Bristol-Myers Company Antipsychotic benzisothiazole S-oxide compound
NL8601494A (nl) * 1985-06-22 1987-01-16 Sandoz Ag Thiazolen, hun bereiding en farmaceutische preparaten die ze bevatten.
US4732984A (en) * 1985-10-17 1988-03-22 American Home Products Corporation Piperazinoisothiazolones with psychotropic activity
JPS6310786A (ja) * 1986-07-01 1988-01-18 Sumitomo Pharmaceut Co Ltd 新規イミド誘導体およびその製造法
JPS6310760A (ja) * 1986-07-01 1988-01-18 Sumitomo Pharmaceut Co Ltd イミド誘導体の新規製造法
DD263531A5 (de) * 1986-10-21 1989-01-04 ������@���Kk�� Verfahren zur herstellung von verbrueckten bicyclischen imidverbindungen
US4748240A (en) * 1987-04-03 1988-05-31 American Home Products Corporation Psychotropic bicyclic imides
US4883795A (en) * 1988-01-22 1989-11-28 Pfizer Inc. Piperazinyl-heterocyclic compounds
JPH0310760A (ja) * 1989-06-09 1991-01-18 Nippon Spindle Mfg Co Ltd 結晶質脆性材料切断用ワイヤソー

Also Published As

Publication number Publication date
ATE92063T1 (de) 1993-08-15
NO911042L (no) 1991-05-15
MY104207A (en) 1994-02-28
IE61413B1 (en) 1994-11-02
FI911285A0 (fi) 1991-03-15
KR930002568B1 (ko) 1993-04-03
NZ230672A (en) 1990-12-21
DK456389D0 (da) 1989-09-15
DE68907845D1 (de) 1993-09-02
EP0364091A1 (en) 1990-04-18
IL91552A0 (en) 1990-04-29
KR900004730A (ko) 1990-04-12
WO1990002552A1 (en) 1990-03-22
ES2058542T3 (es) 1994-11-01
PT91703B (pt) 1995-07-18
AU607354B2 (en) 1991-02-28
ZA897049B (en) 1991-04-24
JPH02121986A (ja) 1990-05-09
US5077295A (en) 1991-12-31
CA1339314C (en) 1997-08-19
IL91552A (en) 1994-02-27
JPH0631231B2 (ja) 1994-04-27
HUT61760A (en) 1993-03-01
NO911042D0 (no) 1991-03-15
DK175200B1 (da) 2004-07-05
EP0364091B1 (en) 1993-07-28
IE892949L (en) 1990-03-16
AU4150689A (en) 1990-03-22
PT91703A (pt) 1990-03-30
DE68907845T2 (de) 1993-11-11

Similar Documents

Publication Publication Date Title
IS3156A7 (is) Aðferð við framleiðslu á N1-súbstitúeruðum bensimidasólafleiðum til að nota við lækningar
DK233586A (da) 5-substituerede 1,3-thiazolidon-2,4-dion forbindelser og farmaceutiske praeparater indeholdende disse
MY102016A (en) Thiazolidinedione derivatives, their production and use.
DK158838C (da) Quinazolinderivater, en fremgangsmaade til fremstilling deraf, farmaceutiske praeparater indeholdende derivater samt anvendelse af derivaterne til fremstilling af medikamenter
NO163569C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 6-thioxanthinderivater.
DK499088A (da) 1-oe(2-pyrimidinyl)-aminoalkylaapiperidinderivater, fremgangsmaade til fremstilling deraf og laegemiddel indeholdende saadanne derivater
ATE56211T1 (de) 2-phenylbenzoxepin-derivat.
DK53285D0 (da) (-)-trans-4(4-fluorphenyl)-3-(4-methoxyphenoxy)-methylpiperidin, farmaceutisk acceptable syreadditionssalte heraf og farmaceutisk praeparat indeholdende samme
DE3688087T2 (de) Cephemverbindungen, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate.
DK456389A (da) Broforbundne bicycliske imider med en 4-oe4-(3-benzisothiazolyl)-1-piperazinylaabutylgruppe knyttet til imidnitrogenatomer og antipsykotisk farmaceutiske praeparater indeholdende disse
DK156474C (da) S-(carbamoylphenylselenyl)-derivater af mercaptaner, fremgangsmaade til fremstilling deraf samt farmaceutiske praeparater indeholdende samme
DK591488D0 (da) 1-acyl-3-oe4-(2-pyrimidinyl)-1-piperazinylaapropan-forbindelser, deres anvendelse til fremstilling af et angstdaempende laegemiddel og farmaceutiske praeparater indeholdende disse forbindelser
DK248886A (da) Spiro-imidazolidin-forbindelser og farmaceutiske praeparater indeholdende disse
ATE21101T1 (de) N-iminopyridinium-betain-derivate, ihre herstellung und ihre verwendung als arzneimittel.
FI864970A (fi) Nya kristallina salter av aryloxi-propanolaminer, foerfarande foer deras framstaellning och deras anvaendning.
DE3751597D1 (de) Verwendung von 15-Deoxyspergualin als Arzneimittel.
DK614989A (da) Indolderivater, fremgangsmaade til deres fremstilling og farmaceutiske midler indeholdende dem
NO164170C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 1-benzhydryl-4-cinnamyl-piperazinderivater.
DK592988D0 (da) Laegemiddel, deri indeholdende phosphorholdige 2-isoxazoliner og isoxazoler, samt fremstilling af disse heterocycliske forbindelser
DK400385A (da) Arphameninderivater, fremgangsmaade til deres fremstilling samt anvendelse heraf som laegemiddel
MY105044A (en) Thieno (3', 4' -4, 5)imidazo(2,1-b)thiazole derivatives, a process for their preparation and their use in medicaments.

Legal Events

Date Code Title Description
PBP Patent lapsed

Country of ref document: DK