DK248886A - Spiro-imidazolidin-forbindelser og farmaceutiske praeparater indeholdende disse - Google Patents

Spiro-imidazolidin-forbindelser og farmaceutiske praeparater indeholdende disse Download PDF

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Publication number
DK248886A
DK248886A DK248886A DK248886A DK248886A DK 248886 A DK248886 A DK 248886A DK 248886 A DK248886 A DK 248886A DK 248886 A DK248886 A DK 248886A DK 248886 A DK248886 A DK 248886A
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DK
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Prior art keywords
spiro
pharmaceutical preparations
preparations containing
imidazolidine compounds
compounds
Prior art date
Application number
DK248886A
Other languages
English (en)
Other versions
DK248886D0 (da
Inventor
Christopher Andrew Lipinski
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of DK248886D0 publication Critical patent/DK248886D0/da
Publication of DK248886A publication Critical patent/DK248886A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/12—Ophthalmic agents for cataracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK248886A 1985-05-29 1986-05-28 Spiro-imidazolidin-forbindelser og farmaceutiske praeparater indeholdende disse DK248886A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/738,924 US4575507A (en) 1985-05-29 1985-05-29 Spiro-imidazolidines as aldose reductase inhibitors and their pharmaceutical use

Publications (2)

Publication Number Publication Date
DK248886D0 DK248886D0 (da) 1986-05-28
DK248886A true DK248886A (da) 1986-11-30

Family

ID=24970055

Family Applications (1)

Application Number Title Priority Date Filing Date
DK248886A DK248886A (da) 1985-05-29 1986-05-28 Spiro-imidazolidin-forbindelser og farmaceutiske praeparater indeholdende disse

Country Status (21)

Country Link
US (1) US4575507A (da)
EP (1) EP0203791B1 (da)
JP (1) JPS61277671A (da)
KR (1) KR890001548B1 (da)
AT (1) ATE46332T1 (da)
AU (1) AU560429B2 (da)
DD (5) DD264215A5 (da)
DE (1) DE3665584D1 (da)
DK (1) DK248886A (da)
EG (1) EG17859A (da)
ES (2) ES8800228A1 (da)
FI (1) FI862251A (da)
GR (1) GR861388B (da)
HU (4) HUT49879A (da)
IL (1) IL78954A (da)
NO (1) NO862123L (da)
NZ (1) NZ216334A (da)
PH (1) PH22213A (da)
PL (5) PL147397B1 (da)
PT (1) PT82650B (da)
ZA (1) ZA863934B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4680306A (en) * 1984-07-20 1987-07-14 Pfizer Inc. Sprio-imidazolones for treatment of diabetes complications
US4762839A (en) * 1985-06-06 1988-08-09 Tanabe Seiyaku Co., Ltd. Quinazolinone copmpounds useful for the prophyloxis and treatment of diabetic complications
JPS63132889A (ja) * 1986-11-21 1988-06-04 Tanabe Seiyaku Co Ltd キナゾリノン誘導体
JPH01503460A (ja) * 1987-03-20 1989-11-22 アルコン　ラボラトリーズ、インコーポレイテツド 糖尿病における、インシュリン感受性を増強させるためのアルドース還元酵素阻害剤の使用
US5004751A (en) * 1987-08-28 1991-04-02 Mochida Pharmaceutical Co., Ltd. Hydantoin derivatives
US5202339A (en) * 1987-08-28 1993-04-13 Mochida Pharmaceutical Co., Ltd. Hydantoin derivatives
AU623676B2 (en) * 1988-08-24 1992-05-21 Mochida Pharmaceutical Co., Ltd. Hydantoin derivatives
US5068332A (en) * 1990-10-12 1991-11-26 American Home Products Corporation Alkylidene analogs of 1'-aminospiro[isoquinoline-4(1H),3'-pyrrolidine]-1,2',3,5'(2H)-tetrones useful as aldose reductase inhibitors
US8326636B2 (en) * 2008-01-16 2012-12-04 Canyon Ip Holdings Llc Using a physical phenomenon detector to control operation of a speech recognition engine
MX2014009033A (es) * 2012-02-09 2014-10-17 Boehringer Ingelheim Int Metodo para la sintesis estereoselectiva de 9-hidroxi-5-oxo-1,4-di aza-espiro[5,5]undecanos 1,4-protegidos.

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1088945A (en) * 1976-10-18 1980-11-04 Pfizer Limited Hydantoin derivatives as therapeutic agents
US4117230A (en) 1976-10-18 1978-09-26 Pfizer Inc. Hydantoin derivatives as therapeutic agents
US4235911A (en) * 1979-06-13 1980-11-25 Pfizer Inc. Hydantoin derivatives
US4248882A (en) * 1980-02-12 1981-02-03 Pfizer Inc. Treating diabetes-associated complications with hydantoin amines
JPS5745185A (en) * 1980-07-21 1982-03-13 Eisai Co Ltd Hydantoin derivative and its preparation
EP0109231B1 (en) * 1982-11-10 1986-10-22 Pfizer Inc. Sorbinil by optical resolution with aminopinane derivatives
US4556670A (en) 1982-12-06 1985-12-03 Pfizer Inc. Spiro-3-hetero-azolones for treatment of diabetic complications
HU193191B (en) * 1982-12-06 1987-08-28 Pfizer Process for preparing spiro-hetero-azolones
DE3561198D1 (en) * 1984-03-23 1988-01-28 Pfizer Spiro-indenes and spiro-1,2-dihydro-naphthalenes for treatment of diabetic complications
US4762838A (en) 1985-08-30 1988-08-09 Pfizer Inc. Quinazolin-4(3H)-one derivatives as anticoccidial agents

Also Published As

Publication number Publication date
DD251972A5 (de) 1987-12-02
ES555375A0 (es) 1987-11-01
EP0203791B1 (en) 1989-09-13
DE3665584D1 (de) 1989-10-19
DD264215A5 (de) 1989-01-25
JPS61277671A (ja) 1986-12-08
IL78954A (en) 1989-09-28
IL78954A0 (en) 1986-09-30
PL146020B1 (en) 1988-12-31
HU893127D0 (en) 1990-01-28
DD264214A5 (de) 1989-01-25
PL147398B1 (en) 1989-05-31
ES8801830A1 (es) 1988-02-16
ES557391A0 (es) 1988-02-16
DK248886D0 (da) 1986-05-28
HU196060B (en) 1988-09-28
HUT49879A (en) 1989-11-28
PT82650B (pt) 1988-11-30
PT82650A (en) 1986-06-01
NZ216334A (en) 1988-08-30
ATE46332T1 (de) 1989-09-15
KR860008984A (ko) 1986-12-19
DD273258A5 (de) 1989-11-08
FI862251A (fi) 1986-11-30
HUT49882A (en) 1989-11-28
HUT44767A (en) 1988-04-28
PL266363A1 (en) 1988-03-03
PL266364A1 (en) 1988-03-03
KR890001548B1 (en) 1989-05-08
PL147397B1 (en) 1989-05-31
EG17859A (en) 1991-11-30
US4575507A (en) 1986-03-11
AU560429B2 (en) 1987-04-09
AU5801286A (en) 1987-01-08
DD264213A5 (de) 1989-01-25
ZA863934B (en) 1988-01-27
PL147400B1 (en) 1989-05-31
PL266365A1 (en) 1988-03-03
NO862123L (no) 1986-12-01
PL147399B1 (en) 1989-05-31
GR861388B (en) 1986-09-17
PL266366A1 (en) 1988-03-03
FI862251A0 (fi) 1986-05-28
EP0203791A1 (en) 1986-12-03
ES8800228A1 (es) 1987-11-01
PH22213A (en) 1988-06-28
HU199845B (en) 1990-03-28

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